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RAYVOW 100 mg FILM-COATED TABLETS

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Doctor

Maria Martelli

Anaesthesiology 12 years exp.

Dr Maria Martelli is a medical doctor specialising in anaesthesiology and pain medicine. She provides online consultations for adults, focusing on the assessment and management of acute, chronic, and complex pain conditions, as well as supportive care in serious illness. She graduated from the Medical University of Silesia in Katowice and completed her specialisation in Anaesthesiology and Intensive Care. Alongside hospital work, she has extensive experience in home and inpatient hospice care, supporting patients with severe pain and advanced disease. Since 2021, she has been a certified specialist and continues to work in anaesthesiology, intensive care, and pain treatment. Patients consult her for: 

  • Chronic pain lasting more than 3 months (musculoskeletal, neuropathic, mixed pain).
  • Acute pain requiring medical assessment and treatment planning.
  • Post-operative pain and recovery support.
  • Cancer-related pain and symptom relief.
  • Palliative care support and quality-of-life improvement.
  • Adjustment and optimisation of pain medication.
  • Second opinions for complex or treatment-resistant pain.

Dr Martelli takes a structured, evidence-based approach, carefully analysing symptoms, previous treatments, and overall health status. Her consultations focus on realistic pain control goals, safety of therapy, and improving daily functioning. She is especially attentive to patients living with long-term pain or serious illness, providing clear explanations, compassionate guidance, and medically sound recommendations adapted to each individual situation.

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€99
This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use RAYVOW 100 mg FILM-COATED TABLETS

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

Show original

Introduction

Package Leaflet: Information for the Patient

RAYVOW 50 mg film-coated tablets

RAYVOW 100 mg film-coated tablets

RAYVOW 200 mg film-coated tablets

lasmiditan

This medicine is subject to additional monitoring, which will allow for quick identification of new safety information. You can help by reporting any side effects you may get. The last section of section 4 will tell you how to report side effects.

Read all of this leaflet carefully before you start taking this medicine, because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack

  1. What is RAYVOW and what is it used for
  2. What you need to know before you take RAYVOW
  3. How to take RAYVOW
  4. Possible side effects
  5. Storage of RAYVOW
  6. Contents of the pack and other information

1. What is RAYVOW and what is it used for

RAYVOW contains the active substance lasmiditan, which is used to treat the headache phase of migraine attacks with or without aura in adults.

RAYVOW helps to reduce or eliminate the pain and other symptoms associated with migraine. Pain relief can be felt even 30 minutes after taking RAYVOW.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you take RAYVOW

Do not take RAYVOW

  • if you are allergic to lasmiditan or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions

Do not engage in activities that require your full attention, such as driving or operating machinery, within 8 hours after taking each dose of RAYVOW, even if you feel well enough to do so, because it may affect your ability to drive or operate machinery safely. If you cannot do so, you should not take RAYVOW.

Consult your doctor or pharmacist before starting to take RAYVOW if:

  • you are taking medicines that increase serotonin levels (see “Other medicines and RAYVOW”). These medicines increase the risk of side effects such as serotonin syndrome (a rare reaction that can cause mental changes, such as seeing things that do not exist (hallucinations), agitation or coma; rapid heartbeat; changes in blood pressure; high body temperature; muscle stiffness; difficulty walking; nausea, vomiting or diarrhea).
  • you are taking other medicines or substances that cause drowsiness, such as sleeping pills, medicines for psychiatric disorders or alcohol.
  • you have ever been addicted to prescription medicines, alcohol or other drugs.

If you repeatedly use any medicine for the treatment of migraine for several days or weeks, this may cause you to have daily headaches in the long term. Tell your doctor if you experience this, as it may be necessary to interrupt treatment for a while.

Children and adolescents

RAYVOW should not be given to patients under 18 years of age because there is not enough information on how it works in this age group.

Other medicines and RAYVOW

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.

In particular, tell your doctor or pharmacist before taking RAYVOW if you are taking:

  • medicines that reduce heart rate, such as propranolol
  • medicines that increase serotonin levels (including SSRIs, SNRIs, tricyclic antidepressants, monoamine oxidase inhibitors (MAOIs) or triptans)
  • digoxin (used to treat heart disorders)

Taking RAYVOW with alcohol

Caution should be exercised if you drink alcohol while taking RAYVOW.

Pregnancy, breastfeeding and fertility

If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine. It is not known if RAYVOW will harm your unborn baby. RAYVOW is not recommended during pregnancy.

If you are breastfeeding, ask your doctor for advice before taking this medicine. It is not known if lasmiditan passes into breast milk. Breastfeeding should be avoided for 24 hours after treatment to minimize the amount of lasmiditan that is passed to your baby.

It is not known if RAYVOW affects fertility.

Driving and using machines

RAYVOW affects your ability to drive and use machines. Do not engage in activities that require your full attention, such as driving or operating machinery, for at least 8 hours after taking each dose of lasmiditan, even if you feel well enough to do so. If you cannot do so, you should not take RAYVOW.

RAYVOW contains sodium

This medicine contains less than 1 mmol of sodium (23 mg) per tablet; this is essentially “sodium-free”.

3. How to take RAYVOW

Follow exactly the administration instructions of this medicine given by your doctor or pharmacist. In case of doubt, consult your doctor or pharmacist again.

  • The recommended initial dose is 100 mg of lasmiditan. Your doctor will decide which dose of lasmiditan is suitable for you.
  • If you do not stop feeling pain after the first tablet, do not take a second tablet for the same attack as it is unlikely to be effective.
  • If after a first tablet of 50 mg or 100 mg your migraine is completely resolved and then recurs, you can take a second tablet of the same dose no earlier than 2 hours after the first dose.
  • Do not take more than 200 mg in 24 hours.
  • If your dose of 100 mg does not relieve your migraine or causes side effects, talk to your doctor, who may recommend a higher dose (200 mg) or a lower dose (50 mg).

Use in children and adolescents and patients with hepatic impairment

RAYVOW is not recommended in children and adolescents (under 18 years of age) or in patients with severe liver problems.

Method of administration

RAYVOW is for oral use. You should swallow your tablet with a little water during the headache phase of your migraine attack. You can take the tablet with or without food.

If you take more RAYVOW than you should

If you take more RAYVOW than you should, contact your doctor immediately. You may develop some of the side effects described in section 4.

If you forget to take RAYVOW

RAYVOW is indicated for the acute treatment of migraines and should only be taken when needed.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Tell your doctor immediatelyif you experience any of the following serious side effects after taking this medicine:

  • allergic reactions including rash and swelling of the eyelids, face or lips (uncommon)
  • signs and symptoms of serotonin syndrome, a rare reaction that can cause mental changes, such as seeing things that do not exist (hallucinations), agitation or coma; rapid heartbeat; changes in blood pressure; high body temperature; muscle stiffness; difficulty walking; gastrointestinal symptoms such as nausea, vomiting or diarrhea.

Other side effects may include:

Very common(may affect more than 1 in 10 people):

  • Dizziness

Common(may affect up to 1 in 10 people):

  • Feeling of sleepiness
  • Feeling of tiredness
  • Pins and needles or tingling in the skin
  • Feeling of nausea
  • Numbness
  • General feeling of being unwell
  • Feeling of spinning or loss of balance
  • Muscle weakness
  • Difficulty controlling movement, e.g. lack of coordination
  • Abnormal sensation
  • Vomiting
  • Poor quality sleep
  • Feeling your heart beating in your chest, e.g. palpitations
  • Vision problems, e.g. blurred vision

Uncommon(may affect up to 1 in 100 people):

  • Feeling of restlessness or inability to sit or stand still
  • Agitation or tremors
  • Feeling anxious
  • Feeling hot or cold
  • Muscle cramp
  • Slowing down
  • Discomfort in arms or legs
  • Difficulty concentrating
  • Changes in thinking, such as memory loss or confused thinking
  • Feeling that your head is not working properly
  • Speech problems, e.g. stuttering
  • Feeling confused
  • Chest discomfort
  • Feeling extremely happy or excited
  • Seeing or hearing things that do not exist
  • Shortness of breath or difficulty breathing

In the hours following administration, lasmiditan has been associated with a decrease in heart rate (an average of around 5 to 10 beats per minute) and a small increase in blood pressure.

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the national reporting system listed in Appendix V. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of RAYVOW

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the blister and carton after “EXP”. The expiry date refers to the last day of the month shown.

This medicine does not require any special storage conditions.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help protect the environment.

6. Contents of the pack and other information

Composition of RAYVOW

  • The active substanceis lasmiditan.
  • RAYVOW 50 mg film-coated tablets

Each film-coated tablet contains 50 mg of lasmiditan (as succinate).

  • RAYVOW 100 mg film-coated tablets

Each film-coated tablet contains 100 mg of lasmiditan (as succinate).

  • RAYVOW 200 mg film-coated tablets

Each film-coated tablet contains 200 mg of lasmiditan (as succinate).

  • The otheringredients are: croscarmellose sodium, magnesium stearate, microcrystalline cellulose, sodium lauryl sulfate, pregelatinized starch
  • For the grey color mixture of 50 mg and 200 mg: polyvinyl alcohol, titanium dioxide (E171), macrogol 3350, talc, iron oxide black (E172)
  • For the purple color mixture of 100 mg: polyvinyl alcohol, titanium dioxide (E171), macrogol 3350, talc, iron oxide black (E172), iron oxide red (E172)

Appearance and packaging

RAYVOW is available in 3 doses: 50 mg, 100 mg and 200 mg

  • The 50 mg film-coated tablets are oval, light grey, with “4312” on one side and “L-50” on the other.
  • The 100 mg film-coated tablets are oval, light purple, with “4491” on one side and “L-100” on the other.
  • The 200 mg film-coated tablets are oval, grey, with “4736” on one side and “L-200” on the other.

RAYVOW is available in precut unit dose blisters of polychlorotrifluoroethylene/polyvinyl chloride (PCTFE/PVC) and polyvinyl chloride (PVC) sealed with an aluminum foil in packs of 2 x 1, 4 x 1, 6 x 1, 12 x 1 and 16 x 1 film-coated tablets. Not all pack sizes may be marketed.

Marketing authorisation holder

Eli Lilly Nederland B.V.,

Papendorpseweg 83,

3528 BJ Utrecht,

Netherlands

Manufacturer

Lilly S.A.,

Avda. de la Industria, 30,

28108 Alcobendas,

Madrid,

Spain

You can request more information about this medicine from the local representative of the marketing authorisation holder:

Belgium/Belgique/Belgien

Eli Lilly Benelux S.A./N.V.

Tel: + 32-(0)2 548 84 84

Lithuania

Eli Lilly Lietuva

Tel: +370 (5) 2649600

Text in Bulgarian language with contact information of a pharmaceutical company and phone number

Luxembourg/Luxemburg

Eli Lilly Benelux S.A./N.V.

Tel: + 32-(0)2 548 84 84

Czech Republic

ELI LILLY CR, s.r.o.

Tel: + 420 234 664 111

Hungary

Lilly Hungária Kft.

Tel: + 36 1 328 5100

Denmark

Eli Lilly Danmark A/S

Tel: +45 45 26 60 00

Malta

Charles de Giorgio Ltd.

Tel: + 356 25600 500

Germany

Lilly Deutschland GmbH

Tel: + 49-(0) 6172 273 2222

Netherlands

Eli Lilly Nederland B.V.

Tel: + 31-(0) 30 60 25 800

Estonia

Eli Lilly Nederland B.V.

Tel: +372 6 817 280

Norway

Eli Lilly Norge A.S.

Tel: + 47 22 88 18 00

Greece

ΦΑΡΜΑΣΕΡΒ-ΛΙΛΛΥ Α.Ε.Β.Ε.

Tel: +30 210 629 4600

Austria

Eli Lilly Ges.m.b.H.

Tel: + 43-(0) 1 711 780

Spain

Organon Salud, S.L.

Tel: +34 91 591 12 79

Poland

Eli Lilly Polska Sp. z o.o.

Tel: +48 22 440 33 00

France

Organon France

Tel: +33-(0) 1 57 77 32 00

Portugal

Lilly Portugal Produtos Farmacêuticos, Lda

Tel: + 351-21-4126600

Croatia

Eli Lilly Hrvatska d.o.o.

Tel: +385 1 2350 999

Romania

Eli Lilly România S.R.L.

Tel: + 40 21 4023000

Ireland

Eli Lilly and Company (Ireland) Limited

Tel: + 353-(0) 1 661 4377

Slovenia

Eli Lilly farmacevtska družba, d.o.o.

Tel: +386 (0)1 580 00 10

Iceland

Icepharma hf.

Tel: + 354 540 8000

Slovakia

Eli Lilly Slovakia s.r.o.

Tel: + 421 220 663 111

Italy

Eli Lilly Italia S.p.A.

Tel: + 39- 055 42571

Finland

Oy Eli Lilly Finland Ab

Tel: + 358-(0) 9 85 45 250

Cyprus

Phadisco Ltd

Tel: +357 22 715000

Sweden

Eli Lilly Sweden AB

Tel: + 46-(0) 8 7378800

Latvia

Eli Lilly (Suisse) S.A Parstavnieciba Latvija

Tel: +371 67364000

United Kingdom (Northern Ireland)

Eli Lilly and Company (Ireland) Limited

Tel: + 353-(0) 1 661 4377

Date of last revision of this leaflet:

Other sources of information

Detailed information on this medicine is available on the European Medicines Agency website: http://www.ema.europa.eu, and on the website of the Spanish Agency for Medicines and Health Products (AEMPS) (http://www.aemps.gob.es/).

Online doctors for RAYVOW 100 mg FILM-COATED TABLETS

Discuss questions about RAYVOW 100 mg FILM-COATED TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (2)
Doctor

Alexander Nazarchuk

Allergology 7 years exp.

Dr. Alexander Nazarchuk is a physician specialising in allergology and internal medicine. He provides online consultations for adults, following the principles of evidence-based medicine — no outdated treatments or unnecessary tests, with clear explanations and a personalised approach. He helps patients with a wide range of allergic and therapeutic conditions, from common day-to-day complaints to complex cases involving allergies, gastrointestinal issues, cardiovascular concerns, respiratory symptoms, and more.

You can consult Dr. Nazarchuk for:

  • Test interpretation and guidance on diagnostic plans.
  • Allergic rhinitis, hay fever, bronchial asthma (including severe cases).
  • Food and drug allergies, skin rashes, angioedema.
  • Atopic dermatitis, urticaria, contact allergies.
  • Allergen-specific immunotherapy (AIT) – initiation and ongoing management.
  • Abdominal pain, bloating, changes in bowel habits, nausea, heartburn.
  • High blood pressure and adjustment of baseline antihypertensive therapy.
  • Hyperlipidaemia and elevated cholesterol.
  • Cough, nasal congestion, fever, sore throat.
  • Anaemia, including iron deficiency and related conditions.
  • Other issues related to allergology and internal medicine.

During consultations, Dr. Nazarchuk takes a thorough, structured approach — analysing symptoms, identifying potential causes, and helping patients make informed decisions. Whether treatment, further investigation, or monitoring is needed, he explains each step clearly so you understand your health and how best to manage it.

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5.0 (5)
Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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0.0 (0)
Doctor

Maria Martelli

Anaesthesiology 12 years exp.

Dr Maria Martelli is a medical doctor specialising in anaesthesiology and pain medicine. She provides online consultations for adults, focusing on the assessment and management of acute, chronic, and complex pain conditions, as well as supportive care in serious illness. She graduated from the Medical University of Silesia in Katowice and completed her specialisation in Anaesthesiology and Intensive Care. Alongside hospital work, she has extensive experience in home and inpatient hospice care, supporting patients with severe pain and advanced disease. Since 2021, she has been a certified specialist and continues to work in anaesthesiology, intensive care, and pain treatment. Patients consult her for: 

  • Chronic pain lasting more than 3 months (musculoskeletal, neuropathic, mixed pain).
  • Acute pain requiring medical assessment and treatment planning.
  • Post-operative pain and recovery support.
  • Cancer-related pain and symptom relief.
  • Palliative care support and quality-of-life improvement.
  • Adjustment and optimisation of pain medication.
  • Second opinions for complex or treatment-resistant pain.

Dr Martelli takes a structured, evidence-based approach, carefully analysing symptoms, previous treatments, and overall health status. Her consultations focus on realistic pain control goals, safety of therapy, and improving daily functioning. She is especially attentive to patients living with long-term pain or serious illness, providing clear explanations, compassionate guidance, and medically sound recommendations adapted to each individual situation.

Camera Book a video appointment
€99
0.0 (0)
Doctor

Joao Silva

General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

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€55

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Frequently Asked Questions

Is a prescription required for RAYVOW 100 mg FILM-COATED TABLETS?

RAYVOW 100 mg FILM-COATED TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in RAYVOW 100 mg FILM-COATED TABLETS?

The active ingredient in RAYVOW 100 mg FILM-COATED TABLETS is lasmiditan. This information helps identify medicines with the same composition but different brand names.

How much does RAYVOW 100 mg FILM-COATED TABLETS cost in pharmacies?

The average pharmacy price for RAYVOW 100 mg FILM-COATED TABLETS is around 15.61 EUR. Prices may vary depending on the manufacturer and dosage form.

Who manufactures RAYVOW 100 mg FILM-COATED TABLETS?

RAYVOW 100 mg FILM-COATED TABLETS is manufactured by Eli Lilly Nederland B.V.. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of RAYVOW 100 mg FILM-COATED TABLETS online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether RAYVOW 100 mg FILM-COATED TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy RAYVOW 100 mg FILM-COATED TABLETS in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy RAYVOW 100 mg FILM-COATED TABLETS in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to RAYVOW 100 mg FILM-COATED TABLETS?

Other medicines with the same active substance (lasmiditan) include RAYVOW 50 mg FILM-COATED TABLETS, ALMOGRAN 12.5 mg FILM-COATED TABLETS, ALMOTRIPTAN CINFA 12.5 mg FILM-COATED TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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