Bg pattern

OPTALIDON 500 mg/75 mg SUPPOSITORIES

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use OPTALIDON 500 mg/75 mg SUPPOSITORIES

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

Show original

Introduction

Patient Information Leaflet

Optalidon 500 mg/75mg suppositories Propyphenazone, anhydrous caffeine

Read this leaflet carefully before starting to use this medicine, as it contains important information for you.

Follow the administration instructions for the medicine contained in this leaflet or as indicated by your doctor or pharmacist exactly.

  • Keep this leaflet, as you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience side effects, consult your doctor or pharmacist, even if they are not listed in this leaflet. See section 4.
  • You should consult a doctor if it worsens or does not improve after 10 days.

Contents of the Leaflet

  1. What Optalidon is and what it is used for
  2. What you need to know before taking Optalidon
  3. How to take Optalidon
  4. Possible side effects
  5. Storage of Optalidon
  6. Package contents and additional information

1. What Optalidon is and what it is used for

Optalidon is a medicine that contains two active ingredients in combination: propyphenazone for pain, and caffeine, which has a stimulating effect on the nervous system, for somnolence.

It is indicated for adults and children over 12 years old, for the relief of mild or moderate pain, such as headache, toothache, and menstrual pain.

You should consult a doctor if it worsens or does not improve after 10 days.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before taking Optalidon

Do not useOptalidon

  • If you are allergic to propyphenazone or caffeine, or to any of the other components of this medicine (listed in section 6).
  • If you are allergic to medicines that contain metamizole, phenylbutazone, or other components of the pyrazolone group.
  • If you are allergic to medicines that contain aminophylline, dyphylline, oxtriphylline, theobromine, theophylline, or other components of the xanthine group.
  • If you have experienced allergic reactions of an asthmatic type (difficulty breathing, shortness of breath, bronchospasm, and in some cases cough or wheezing) when taking acetylsalicylic acid or other non-steroidal anti-inflammatory drugs.
  • If you have blood disorders (granulocytopenia, agranulocytosis).
  • If you have any metabolic disease such as porphyria (a rare, usually hereditary disorder in which a large amount of porphyrin is eliminated in feces and urine) or congenital glucose-6-phosphate dehydrogenase deficiency.
  • If you have severe liver, kidney, or heart disease (renal, hepatic, or cardiac insufficiency).
  • If you have an anxiety disorder.
  • If you have an active gastroduodenal ulcer.

Warnings and precautions

Consult your doctor or pharmacist before starting to use Optalidon.

Do not exceed the recommended dose in the Posology section, nor use it for more than 10 days. Consult your doctor or pharmacist before starting to use Optalidon if:

  • you have hypertension,
  • you have a gastroduodenal ulcer,
  • you have asthma or severe respiratory diseases (chronic obstructive pulmonary disease, emphysema, chronic bronchitis).

If the pain persists, worsens, or other symptoms appear, especially fever or mouth ulcers, treatment should be discontinued immediately and your doctor consulted.

Caffeine may increase blood glucose levels.

In people with sleep disorders, it is recommended not to take this medicine in the hours before bedtime to avoid possible insomnia.

Athletes should be informed that this medicine contains a component that may result in a positive doping test.

Children and adolescents

It should not be administered to children under 12 years old.

Other medicines and Optalidon

Taking Optalidon with other medicines.

Inform your doctor or pharmacist if you are taking or using, have taken or used recently, or may need to take or use any other medicine. In particular, if you are taking any of the following medicines, it may be necessary to modify the dose of one of them or interrupt treatment:

  • oral anticoagulants (medicines used to "thin" the blood and prevent clot formation) such as warfarin,
  • barbiturics (medicines used to treat seizures),
  • antihistamines (used to reduce the symptoms of allergic reactions),
  • lithium (reducing its therapeutic effect).

Using Optalidon with food and beverages and alcohol

It is recommended to limit the use of products that contain caffeine when being treated with this medicine.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine. This medicine should not be taken during pregnancy or breastfeeding without consulting a doctor.

Do not take Optalidon if you are in the last 3 months of pregnancy, as it may harm the fetus or cause problems during delivery. It may cause kidney and heart problems in the fetus. It may affect your tendency and that of the fetus to bleed and make labor longer than expected. You should not take Optalidon during the first 6 months of pregnancy unless it is absolutely necessary and indicated by your doctor. If you need treatment during this period or while trying to become pregnant, you should use the lowest dose for the shortest possible time. If you take it for more than a few days from the 20th week of pregnancy, Optalidon may cause kidney problems in the fetus, which can lead to low levels of amniotic fluid surrounding the fetus (oligohydramnios) or narrowing of a blood vessel (ductus arteriosus) in the baby's heart. If you need treatment for more days, your doctor may recommend additional monitoring.

Driving and using machines

Do not drive or operate hazardous machinery, as this medicine can cause drowsiness or decreased reaction time at the recommended doses.

3. How to take Optalidon

Follow the administration instructions for this medicine indicated by your doctor or pharmacist exactly. If in doubt, consult your doctor or pharmacist again.

Rectal route.

The recommended dose is 1 suppository per day. The maximum dose will be 2 suppositories per day.

Always use the lowest effective dose. Administration of the preparation is subject to the appearance of pain. As it disappears, this medication should be discontinued.

Instructions for correct administration of the preparation

If the suppository is too soft to insert, cool it in the refrigerator for 30 minutes or put it under cold running water before removing the plastic wrapper or after if necessary to prevent it from softening.

Use in children and adolescents

It should not be used in children under 12 years old.

If you use more Optalidon than you should

Symptoms of overdose are: abdominal pain, nausea, vomiting, drowsiness, excitement, convulsions, and coma.

In case of overdose or accidental ingestion, go immediately to a medical center or call the Toxicology Information Service (Telephone: (91)-562.04.20), indicating the medicine and the amount ingested.

If you forget to use Optalidon

Do not use a double dose to make up for forgotten doses.

If you stop treatment with Optalidon

If you have any other doubts about the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everyone gets them.

They are not usually observed at the recommended doses. In hypersensitive subjects, very rare cutaneous allergic reactions have been observed: redness or itching, skin alterations with blister formation, urticaria, or shock. In this case, treatment should be discontinued and a doctor consulted. Occasionally, dizziness, nausea, nervousness, difficulty sleeping, rapid heartbeats, or gastrointestinal irritation may appear.

Reporting side effects

If you experience any type of side effect, consult your doctor or pharmacist, even if it is a possible side effect not listed in this leaflet. You can also report them directly through the Spanish Medicines and Health Products Agency's website: www.notificaram.es.

By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Optalidon

Keep this medicine out of the sight and reach of children. No special storage conditions are required.

Do not use this medicine after the expiration date shown on the label and carton after CAD. The expiration date is the last day of the month indicated.

Medicines should not be disposed of through wastewater or household waste. Deposit the packaging and medicines you no longer need at the pharmacy's SIGRE point. Ask your pharmacist how to dispose of the packaging and medicines you no longer need. This will help protect the environment.

6. Package contents and additional information

Composition of Optalidon

Per suppository:

The active ingredients are propyphenazone (DCI) 500 mg, anhydrous caffeine 75 mg.

The other components (excipients) are yellow iron oxide, red iron oxide, Sorbitan laurate (Span 20), and suppository mass.

Appearance of the product and package contents

Package with 6 suppositories.

Marketing authorization holder

Perrigo España S.A.

Pza de Xavier Cugat 2 Edificio D planta 1 08174 Sant Cugat del Valles

Barcelona, Spain

Manufacturer

MIPHARM S.P.A.,

Via B. Quaranta, 12, 1-201 40, Italy

Date of the last revision of this leaflet: 12/2022

Other sources of information

Detailed information about this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es.

Online doctors for OPTALIDON 500 mg/75 mg SUPPOSITORIES

Discuss questions about OPTALIDON 500 mg/75 mg SUPPOSITORIES, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

0.0 (0)
Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
Camera Book a video appointment
€58
0.0 (0)
Doctor

Chikeluo Okeke

General medicine 4 years exp.

Dr Chikeluo Okeke is an internal medicine doctor with extensive international clinical experience. Originally from Nigeria, he has worked across multiple European healthcare systems and currently practises in Sweden. This professional path has given him a strong understanding of different medical approaches and the ability to work effectively with patients from diverse cultural and linguistic backgrounds.

Dr Okeke focuses on general internal medicine and adult primary care, combining clinical accuracy with careful attention to lifestyle, personal context, and everyday health concerns. His consultations are particularly well suited for people who seek medical advice online, live abroad, or need clear guidance without unnecessary complexity.

He provides online consultations covering symptom assessment, prevention, and long-term management of chronic conditions, helping patients understand what is happening and decide on appropriate next steps.

Common reasons for consultation:

  • General internal medicine concerns and initial health assessment.
  • Acute symptoms such as fever, cough, infections, pain, or weakness.
  • Chronic conditions and treatment adjustment.
  • Blood pressure issues, fatigue, metabolic concerns.
  • Preventive consultations and routine check-ups.
  • Interpretation of laboratory results and medical reports.
  • Medical advice for patients receiving care online.

Dr Okeke is known for his clear communication, calm approach, and cultural awareness. He listens carefully, explains medical decisions in a structured way, and supports patients in making informed choices about their health.

Online consultations with Dr Chikeluo Okeke offer reliable internal medicine care without geographic limitations, focused on medical relevance, clarity, and patient comfort.

Camera Book a video appointment
€60
5.0 (1061)
Doctor

Andrei Popov

General medicine 7 years exp.

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

Camera Book a video appointment
€80
5.0 (184)
Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Camera Book a video appointment
€50
0.0 (0)
Doctor

Joao Silva

General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

Camera Book a video appointment
€55
0.0 (0)
Doctor

Bulat Garipov

General medicine 15 years exp.

Dr. Bulat Garipov is a radiologist with more than 15 years of experience, specializing in magnetic resonance imaging (MRI). Throughout his professional career, he has worked in leading diagnostic imaging centers, both in on-site practice and teleradiology, which has allowed him to develop a broad and versatile approach to radiology.

Over the years, he has gained solid experience in interpreting MRI studies in various areas, including:

  •  Neuroimaging
  •  Musculoskeletal system (MSK)
  •  Angiography
  •  Abdomen and pelvis
  •  Soft tissues

Additionally, Dr. Garipov is open to new collaboration opportunities in radiology and teleradiology projects. He offers his expertise in MRI, providing both first and second readings of studies, as well as advanced image interpretation, ensuring accurate and high-quality diagnostics.

You could consult Dr. Bulat Garipov in cases where accurate interpretation of MRI studies or a second expert opinion is required. His expertise is especially valuable in cases of suspected neurological conditions, back and joint pain, vascular disorders, as well as in the diagnosis of abdominal and pelvic diseases. The doctor also provides support in complex or unclear clinical situations, including the review of previously performed studies, which helps improve diagnostic accuracy and determine the optimal treatment strategy. A teleradiology format is available, allowing you to receive a professional opinion remotely.

Camera Book a video appointment
€60

Frequently Asked Questions

Is a prescription required for OPTALIDON 500 mg/75 mg SUPPOSITORIES?
OPTALIDON 500 mg/75 mg SUPPOSITORIES does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in OPTALIDON 500 mg/75 mg SUPPOSITORIES?
The active ingredient in OPTALIDON 500 mg/75 mg SUPPOSITORIES is propyphenazone, combinations excl. psycholeptics. This information helps identify medicines with the same composition but different brand names.
Who manufactures OPTALIDON 500 mg/75 mg SUPPOSITORIES?
OPTALIDON 500 mg/75 mg SUPPOSITORIES is manufactured by Perrigo Espana S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of OPTALIDON 500 mg/75 mg SUPPOSITORIES online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether OPTALIDON 500 mg/75 mg SUPPOSITORIES is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to OPTALIDON 500 mg/75 mg SUPPOSITORIES?
Other medicines with the same active substance (propyphenazone, combinations excl. psycholeptics) include METALGIAL 500 MG/ML ORAL DROPS IN SOLUTION, METAMIZOLE ABABOR 575 mg HARD CAPSULES, METAMIZOL AIKO FARMACEUTICA 575 mg HARD CAPSULES. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
bg-pattern-dark

Stay informed about Oladoctor

News about new services, product updates and useful information for patients.

Follow us on social media