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HBVAXPRO 10 micrograms INJECTABLE SUSPENSION

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use HBVAXPRO 10 micrograms INJECTABLE SUSPENSION

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

HBVAXPRO 10 micrograms, suspension for injection

Hepatitis B vaccine (rDNA)

Read all of this leaflet carefully before you are vaccinated because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor, pharmacist or nurse.
  • If you experience any side effects, talk to your doctor, pharmacist or nurse, even if they are not listed in this leaflet. See section 4.

Contents of the pack

  1. What HBVAXPRO 10 micrograms is and what it is used for
  2. What you need to know before you are given HBVAXPRO 10 micrograms
  3. How HBVAXPRO 10 micrograms is given
  4. Possible side effects
  5. Storage of HBVAXPRO 10 micrograms
  6. Contents of the pack and other information

1. What HBVAXPRO 10 micrograms is and what it is used for

This vaccine is indicated for active immunization against hepatitis B virus infection caused by all known subtypes, in individuals from 16 years of age considered at risk of exposure to hepatitis B virus.

It can be expected that immunization with HBVAXPRO will also prevent hepatitis D, since hepatitis D does not occur in the absence of hepatitis B infection.

The vaccine does not prevent infections caused by other agents such as hepatitis A, hepatitis C, and hepatitis E, or by other pathogens known to infect the liver.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you are given HBVAXPRO 10 micrograms

Do not use HBVAXPRO 10 micrograms

  • if you are allergic to hepatitis B surface antigen or to any of the other components of HBVAXPRO (see section 6).
  • if you have a severe illness with fever.

Warnings and precautions

It can cause severe allergic reactions because it contains latex in the packaging. Consult your doctor, pharmacist or nurse before receiving HBVAXPRO 10 micrograms.

Other vaccines and HBVAXPRO 10 micrograms

HBVAXPRO can be given at the same time as hepatitis B immunoglobulin, in different injection sites.

HBVAXPRO can be used to complete a primary immunization cycle or as a booster dose in individuals who have previously received another hepatitis B vaccine.

HBVAXPRO can be given at the same time as other vaccines, using different injection sites and syringes.

Tell your doctor, pharmacist or nurse if you are taking or have recently taken any other medicines, including those obtained without a prescription.

Pregnancy and lactation

Caution should be exercised when prescribing the vaccine to pregnant or breastfeeding women.

Consult your doctor, pharmacist or nurse before using any medicine.

Driving and using machines

HBVAXPRO is not expected to have a significant effect on the ability to drive and use machines.

HBVAXPRO 10 micrograms contains sodium: this medicine contains less than 23 mg of sodium (1 mmol) per dose; it is essentially "sodium-free".

3. How HBVAXPRO 10 micrograms is given

Dose

The recommended dose per injection (1 ml) is 10 micrograms in individuals from 16 years of age.

A vaccination cycle should include at least three injections.

Two vaccination schedules can be recommended:

  • two injections with a one-month interval followed by a third injection six months after the first administration (0, 1, 6 months).
  • if rapid immunity is required: three injections with a one-month interval and a fourth dose one year later (0, 1, 2, 12 months).

In the event of recent exposure to hepatitis B virus, the first dose of HBVAXPRO can be given along with the appropriate dose of immunoglobulin.

Some local vaccination schedules currently recommend a booster dose. Your doctor, pharmacist or nurse will inform you if you need a booster dose.

HBVAXPRO 10 micrograms is not indicated in individuals under 16 years of age.

The appropriate dose for administration to individuals from birth to 15 years of age is HBVAXPRO 5 micrograms.

Method of administration

The vial should be shaken well until a slightly opaque white suspension is obtained. The doctor or nurse will administer the vaccine by injection into the muscle. The preferred injection site in adults and adolescents is the muscle of the upper arm.

This vaccine should never be administered into a blood vessel.

Exceptionally, the vaccine can be administered subcutaneously in patients with thrombocytopenia (decreased blood platelets) or in individuals at risk of bleeding.

If you miss a dose of HBVAXPRO 10 micrograms

If you miss a scheduled injection, consult your doctor, pharmacist or nurse. Your doctor or nurse will decide when to administer the missed dose.

If you have any further questions about the use of this product, consult your doctor, pharmacist or nurse.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this vaccine can cause side effects, although not everybody gets them.

As with other hepatitis B vaccines, in many cases, a causal relationship between the side effects and the vaccine has not been established.

The most frequently observed side effects are reactions at the injection site: discomfort, redness, and induration.

Other side effects reported very rarely are:

  • Low platelet count, Lymph node disease
  • Allergic reactions
  • Nervous system disorders such as Tingling, Facial paralysis, Inflammations of the nerves including Guillain-Barré syndrome, Optic neuritis causing vision disturbances, Brain inflammation, Exacerbation of multiple sclerosis, Multiple sclerosis, Seizures, Headache, Dizziness, and Fainting
  • Low blood pressure, Inflammation of blood vessels
  • Symptoms similar to asthma
  • Vomiting, Nausea, Diarrhea, Abdominal pain
  • Skin reactions such as Eczema, Rash, Itching, Hives, and Blistering of the skin, Hair loss
  • Joint pain, Arthritis, Muscle pain, Pain in a limb
  • Fatigue, Fever, Undiagnosed illness, Flu-like symptoms
  • Elevation of liver enzymes
  • Inflammation of the eyes causing pain and redness

Reporting of side effects

If you experience any side effects, talk to your doctor, pharmacist or nurse, even if they are not listed in this leaflet. You can also report side effects directly through the national reporting system listed in Appendix V. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of HBVAXPRO 10 micrograms

Keep this vaccine out of the sight and reach of children.

Do not use this vaccine after the expiry date which is stated on the label.

Store in a refrigerator (between 2°C and 8°C).

Do not freeze.

Store in the original packaging to protect from light.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and other information

Composition of HBVAXPRO 10 micrograms

The active substance is:

Recombinant hepatitis B surface antigen (HBsAg)*……..10 micrograms

Adsorbed on amorphous aluminum hydroxyphosphate sulfate (0.50 milligrams Al+)

  • produced in yeast Saccharomyces cerevisiae (strain 2150-2-3) using recombinant DNA technology.

The adjuvant is included in this vaccine to accelerate, enhance, and/or prolong the protective effects of the vaccine.

The other ingredients are sodium chloride (NaCl), sodium borate, and water for injections.

Appearance and packaging of HBVAXPRO 10 micrograms

HBVAXPRO 10 micrograms is a suspension for injection in a vial. Pack sizes of 1 and 10 vials.

Not all pack sizes may be marketed.

Marketing Authorisation Holder and Manufacturer

Merck Sharp & Dohme B.V., Waarderweg 39, 2031 BN Haarlem, Netherlands

For further information about this vaccine, please contact the local representative of the Marketing Authorisation Holder.

België/Belgique/Belgien

MSD Belgium

Tél/Tel: +32(0)27766211

[email protected]

Lietuva

UAB Merck Sharp & Dohme

Tel.: +370.5.2780.247

[email protected]

Text in Bulgarian language with company name Мерк Шарп и Доум България ЕООД and phone number +359 2 819 3737

[email protected]

Luxembourg/Luxemburg

MSD Belgium

Tél/Tel: +32(0)27766211

[email protected]

Ceská republika

Merck Sharp & Dohme s.r.o.

Tel.: +420 233 010 111

[email protected]

Magyarország

MSD Pharma Hungary Kft.

Tel.: + 36.1.888.5300

[email protected]

Danmark

MSD Danmark ApS

Tlf: + 45 4482 4000

[email protected]

Malta

Merck Sharp & Dohme Cyprus Limited.

Tel: 8007 4433 (+356 99917558)

[email protected]

Deutschland

MSD Sharp & Dohme GmbH

Tel: 0800 673 673 673 (+49 (0) 89 4561 0)

[email protected]

Nederland

Merck Sharp & Dohme B.V.

Tel: 0800 9999000 (+31 23 5153153)

[email protected]

Eesti

Merck Sharp & Dohme OÜ,

Tel: +372.614.4200

[email protected]

Norge

MSD (Norge) AS

Tlf: +47 32 20 73 00

[email protected]

Ελλáδα

MSD Α.Φ.Β.Ε.Ε.

Τηλ: +30 210 98 97 300

[email protected]

Österreich

Merck Sharp & Dohme Ges.m.b.H.

Tel: +43 (0) 1 26 044

[email protected]

España

Merck Sharp & Dohme de España, S.A.

Tel: +34 91 321 06 00

[email protected]

Polska

MSD Polska Sp. z o.o.

Tel.: +48.22.549.51.00

[email protected]

France

MSD France

Tél: +33 (0)1 80 46 40 40

Portugal

Merck Sharp & Dohme, Lda

Tel: +351 21 4465700

[email protected]

Hrvatska

Merck Sharp & Dohme d.o.o.

Tel: +385 1 66 11 333

[email protected]

România

Merck Sharp & Dohme Romania S.R.L

Tel: + 4021 529 29 00

[email protected]

Ireland

Merck Sharp & Dohme Ireland (Human Health)

Limited

Tel: +353 (0)1 2998700

[email protected]

Slovenija

Merck Sharp & Dohme, inovativna zdravila

d.o.o.

Tel: +386.1.520.4201

[email protected]

Ísland

Vistor hf.

Sími: + 354 535 7000

Slovenská republika

Merck Sharp & Dohme, s. r. o

Tel: +421 2 58282010

[email protected]

Italia

MSD Italia S.r.l.

Tel: 800 23 99 89 (+39 06 361911)

[email protected]

Suomi/Finland

MSD Finland Oy

Puh/Tel: +358 (0)9 804 650

[email protected]

Κ?προς

Merck Sharp & Dohme Cyprus Limited

Τηλ: 800 00 673 (+357 22866700)

[email protected]

Sverige

Merck Sharp & Dohme (Sweden) AB

Tel: +46 77 5700488

[email protected]

Latvija

SIA Merck Sharp & Dohme Latvija

Tel: +371.67364.224

[email protected]

United Kingdom (Northern Ireland)

Merck Sharp & Dohme Ireland (Human Health)

Limited

Tel: +353 (0)1 2998700

[email protected]

This leaflet was approved on

Detailed information on this medicine is available on the European Medicines Agency website: http://www.ema.europa.eu.

This information is intended for healthcare professionals only:

Instructions

A visual inspection of the vaccine should be performed to detect any foreign particles and/or unusual physical appearance of the contents before administration. The vial should be shaken well until a slightly opaque white suspension is obtained.

Online doctors for HBVAXPRO 10 micrograms INJECTABLE SUSPENSION

Discuss questions about HBVAXPRO 10 micrograms INJECTABLE SUSPENSION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (90)
Doctor

Jorge Correa Bellido

General medicine 7 years exp.

Dr. Jorge Correa Bellido is a Spanish physician who offers online consultations in Spanish and English. He graduated from the University of La Laguna and has a solid background in clinical practice and international research.

Throughout his career, he has participated in various medical and academic projects, including a research fellowship in Spain, where he contributed to evidence-based studies in the field of family medicine. This experience allowed him to broaden his global perspective on healthcare and comprehensive patient care.

Dr. Correa Bellido has worked with several healthcare providers in Spain, focusing particularly on patient-centered care and public health initiatives aimed at communities with limited access to healthcare services.

In addition, he actively participates in international medical conferences and workshops, which allows him to stay up to date with the latest medical advances and collaborate with healthcare professionals from different countries.

Dr. Correa Bellido provides comprehensive care for a wide variety of medical conditions, including:

  • respiratory infections
  • gastrointestinal disorders
  • cardiovascular problems
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  • musculoskeletal and dermatological conditions
  • as well as mental health conditions such as anxiety and depression.

He also treats infectious and allergic diseases, general health concerns, and provides guidance on prevention and healthy lifestyle habits.

His services include virtual consultations, diagnosis and management of acute and chronic diseases, prescription renewals, and personalized medical advice.

With a patient-centered approach and a strong commitment to continuous learning, Dr. Correa Bellido provides accessible and high-quality healthcare to patients both in Spain and around the world.

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Dr. Lizaveta Trafimchuk Takhvaniuk graduated in Medicine and subsequently specialized in Dermatology and Venereology. She has more than 10 years of clinical experience and is licensed to practice in Spain, where she focuses on the comprehensive diagnosis and treatment of dermatological conditions.

Throughout her education and professional career, Dr. Trafimchuk has gained extensive experience in managing diseases of the skin, hair, and nails, as well as in the diagnosis, treatment, and prevention of sexually transmitted infections (STIs). Her clinical approach is based on evidence-based medicine, combined with personalized care tailored to each patient’s needs.

In her daily practice, she treats a wide range of dermatological conditions, including chronic inflammatory dermatoses such as acne, rosacea, atopic dermatitis, psoriasis, and eczema. She also has experience in treating pigmentation disorders, including melasma, post-inflammatory hyperpigmentation, and dyschromia.

She has developed a particular interest in trichology, treating various types of alopecia, chronic hair loss, and scalp disorders. In addition, she has experience in managing infectious dermatoses of fungal, viral, and bacterial origin, as well as in evaluating benign and suspicious skin lesions, with referral to specialized care when necessary.

With a strong interest in a comprehensive approach to skin health, she also treats scars, post-procedural skin changes, and conditions related to hormonal factors and aging, including those associated with pregnancy, menopause, and age-related skin changes.

Thanks to her experience and continuous professional development, Dr. Trafimchuk provides high-quality medical care that is professional, confidential, and aligned with modern dermatology standards.

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Andrei Popov

General medicine 7 years exp.

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

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Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

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Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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Antonio Cayatte

General medicine 44 years exp.

Dr Antonio Cayatte is a physician in General and Acute Medicine with over 30 years of experience across clinical care, medical research, and education. He offers online consultations for adults with a wide range of symptoms, both acute and chronic. His clinical background includes: 

  • assessment of sudden or unclear symptoms
  • ongoing care for chronic conditions
  • follow-up after hospital discharge
  • interpretation of test results
  • medical support while abroad

Dr Cayatte earned his degree from the University of Lisbon and taught internal medicine at Boston University School of Medicine. He holds active medical registrations in both Portugal and the UK and is a Fellow of the American Heart Association. Consultations are available in English and Portuguese. Patients value his clarity, professionalism, and balanced approach to evidence-based care.

Dr. Antonio Cayatte provides comprehensive care for a broad spectrum of common health concerns, including:

  • Respiratory & ENT: acute bronchitis, concerns related to pneumonia, sinusitis, tonsillitis, ear infections, sore throat conditions, and allergic rhinitis
  • Eye Health: allergic and infectious conjunctivitis, as well as red or irritated eyes
  • Digestive & Urinary: gastroesophageal reflux disease (GERD), gastritis, urinary tract infections, and cystitis
  • Chronic Conditions: hypertension, elevated cholesterol, and structured weight management planning

Get HBVAXPRO 10 micrograms INJECTABLE SUSPENSION Prescription Online

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Electronic prescription sent to your email — valid across Spain.

Frequently Asked Questions

Is a prescription required for HBVAXPRO 10 micrograms INJECTABLE SUSPENSION?

HBVAXPRO 10 micrograms INJECTABLE SUSPENSION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in HBVAXPRO 10 micrograms INJECTABLE SUSPENSION?

The active ingredient in HBVAXPRO 10 micrograms INJECTABLE SUSPENSION is hepatitis B, purified antigen. This information helps identify medicines with the same composition but different brand names.

Who manufactures HBVAXPRO 10 micrograms INJECTABLE SUSPENSION?

HBVAXPRO 10 micrograms INJECTABLE SUSPENSION is manufactured by Merck Sharp & Dohme B.V.. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of HBVAXPRO 10 micrograms INJECTABLE SUSPENSION online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether HBVAXPRO 10 micrograms INJECTABLE SUSPENSION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy HBVAXPRO 10 micrograms INJECTABLE SUSPENSION in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy HBVAXPRO 10 micrograms INJECTABLE SUSPENSION in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to HBVAXPRO 10 micrograms INJECTABLE SUSPENSION?

Other medicines with the same active substance (hepatitis B, purified antigen) include ENGERIX-B 20 micrograms/1 ml, PRE-FILLED SYRINGE SUSPENSION FOR INJECTION, ENGERIX-B JUNIOR 10 micrograms/0.5 ml, PRE-FILLED SYRINGE SUSPENSION, FENDRIX, INJECTABLE SUSPENSION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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