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EPISTAXOL 300 mg/5 mg /2 Mg/5 Mg Cutaneous Solution

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Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Epistaxol solución cutánea

Contents of the leaflet

  1. Introduction
  2. What is Epistaxol and what is it used for
  3. What you need to know before starting to use Epistaxol
  4. How to use Epistaxol
  5. Possible Adverse Effects
  6. Conservation of Epistaxol
  7. Contents of the packaging and additional information

Introduction

Prospect: information for the user

Epistaxol topical solution

Epinephrine hydrochloride / Rutoside / Naphazoline hydrochloride / Phenazone

Read this prospect carefully before starting to use this medication, as it contains important information for you.

Follow exactly the medication administration instructions contained in this prospect or those indicated by your doctor, pharmacist, or nurse.

  • Keep this prospect, as you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience adverse effects, consult your doctor, pharmacist, or nurse, even if they do not appear in this prospect.
  • You should consult a doctor if it worsens or does not improve after 2 applications.

1. What is Epistaxol and what is it used for

Epistaxol is a solution applied superficially (topical administration) that facilitates blood coagulation (hemostasis). It causes a rapid contraction of blood vessels (vasoconstriction) and strengthens the walls of blood vessels.

Epistaxol is indicated in cases of mild bleeding in the mucosa (such as in the nasal, oral, genital, or rectal mucosa).

You should consult a doctor if it worsens or does not improve after 2 applications.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before starting to use Epistaxol

No use Epistaxol

  • If you are allergic to adrenaline (epinephrine), naphazoline, phenazone, ritodrine, sympathomimetics (medicines that stimulate the nervous system), flavonoids (components of some plants), or any of the other components of this medication (listed in section 6).
  • If you have heart problems such as heart dilation, coronary insufficiency, cardiac arrhythmias, or heart failure.
  • If you have brain organic injuries such as cerebral arteriosclerosis (chronic inflammation of the brain's arteries with a tendency to obstruct them).
  • If you have closed-angle glaucoma (eye condition characterized by increased intraocular pressure).
  • If you have high blood pressure, hyperthyroidism (thyroid gland alteration), or pheochromocytoma (adrenal gland tumor).
  • During childbirth.

Warnings and Precautions

If after two applications of the product the bleeding does not stop, consult your doctor.

Consult your doctor, pharmacist, or nurse before starting to take Epistaxol:

  • If you have or have had cerebrovascular insufficiency (condition affecting the brain's blood vessels),
  • Heart disease (such as angina or myocardial infarction), chronic lung disease, or urinary difficulties due to prostate hypertrophy,
  • If you have pheochromocytoma, elevated intraocular pressure, and renal damage, high blood pressure, hyperthyroidism, arteriosclerosis,
  • If you are diabetic.

Also, pay attention if you have hypercalcemia or hypocalcemia (blood calcium alteration), elderly patients, and pregnant women.

Children and Adolescents

It is not recommended for use in children under 7 years old.

Use of Epistaxol with other medications

Inform your doctor or pharmacist if you are using, have used recently, or may need to use any other medication.

This is especially important in the case of:

  • Adrenergic blockers (medicines that act on neurons and modify the physiology of organs and tissues),
  • Digitalis glycosides (heart medications),
  • Quinidine, insulin, beta-blockers,
  • Certain antidepressants or guanidine (anti-hypertensive agent),
  • COMT or MAO inhibitors (medicines that act on the metabolic systems responsible for eliminating adrenaline),
  • Thyroid hormones, oxytocin, and certain antihistamines (such as chlorpheniramine), levodopa, and alcohol,
  • Medications that may cause potassium loss, such as diuretics (facilitate urination), aminophylline (medication used to facilitate breathing) or theophylline (antiasmatic, facilitates urination),
  • Hypoglycemic agents (medicines that decrease blood sugar),
  • Use with other sympathomimetics such as isoproterenol, amphetamines, ephedrine, phenylephrine, phenylpropanolamine, as they may increase the effect on the heart and central nervous system.

Laboratory Test Interference

It should be noted that adrenaline (epinephrine) may alter the values of the following blood determinations: increased glucose, false increase in bilirubin values, increased cholesterol, increased lactate and urate, and decreased insulin. An increase in urine vanillylmandelic acid and catecholamines may also be observed.

Pregnancy and Lactation

If you are pregnant or breastfeeding, or think you may be pregnant, consult your doctor or pharmacist before using this medication.

If you are pregnant, do not use Epistaxol unless your doctor considers it absolutely necessary for your treatment.

This medication is excreted in breast milk, so it is recommended to suspend breastfeeding or avoid administering this medication.

Driving and Operating Machines

No problems have been described with the use of this medication.

Epistaxol contains Sodium Metabisulfite (E-223).

This medication may cause severe allergic reactions and bronchospasm (sudden feeling of suffocation) due to the presence of sodium metabisulfite (E-223)

3. How to use Epistaxol

Follow exactly the administration instructions of this medication contained in this leaflet or those indicated by your doctor, pharmacist, or nurse. In case of doubt, ask your doctor, pharmacist, or nurse.

The recommended dose is:

  • Children over 7 years and adults: Apply directly to the bleeding area or through a treatment gauze according to the application method.
  • Children under 7 years:No safety has been established for Epistaxol in children under 7 years. Do not use in children under 7 years.

Apply the product preferably to a gauze and perform a strong pressure on the bleeding area according to the administration standards.

Standards for correct administration

  1. Soak a gauze (or use cotton if gauzes are not available) with the liquid from the bottle (with the bottle inverted and gently squeezing its walls) and proceed to perform a strong pressure on the area that is bleeding for 5-10 minutes.
  2. Leave the dressing for at least one hour. Once this time has passed, we can remove the dressing and check that it has stopped bleeding.
  3. If after removing the dressing, small, very light bleeding is observed, we will perform touches with a gauze or cotton pad soaked with the product to complete the healing.

If a small blood clot has formed in the bleeding point, or if some fibers from the dressing have adhered, do not forcibly remove them, but rather do so with gentle touches using a gauze soaked with the product to help loosen them and avoid possible bleeding when removing them.

If after two applications of the product the desired effect is not achieved, consult with your doctor, as it is necessary for them to evaluate the importance of your bleeding.

If you use more Epistaxol than you should

Due to the characteristics of this preparation, intended for superficial or topical use, it is not expected to experience intoxication phenomena with the use of this specialty.

Accidental overdose of adrenaline may cause sudden increases in blood pressure, which in extreme cases could cause cerebral hemorrhage, and tachycardia (rapid heart rate).

Arrhythmias (alteration of heartbeats) may also appear.

In case of overdose or improper use, consult your doctor or pharmacist immediately or call the Toxicological Information Service, phone 915620420, indicating the medication and the amount used.

If you interrupt treatment with Epistaxol

Try to maintain the pressure with the medication for the indicated time.

If you have any other doubts about the use of this product, ask your doctor, pharmacist, or nurse.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible Adverse Effects

Like all medications, Epistaxol may produce adverse effects, although not everyone will experience them.

With the topical application of Epistaxol, it is unlikely that adverse effects will appear. However, improper use of the medication could lead to the following adverse effects:

  • Frequent (between 1 and 10 in every 100 patients)

Sensation of fear, anxiety, throbbing headache, difficulty breathing, sweating, nausea, vomiting, tremors, and dizziness, tachycardia (palpitations), pallor, mild elevation of blood pressure. These manifestations are not serious and disappear with rest and patient calmness.

  • Rare (between 1 and 10 in every 1,000 patients)

Increased blood pressure (hypertension), which in severe cases can cause cerebral hemorrhage or acute heart failure with pulmonary edema, angina pectoris, ventricular arrhythmias, tachycardia, and abnormal heart contraction (ventricular fibrillation), syncope.

Alucinations, hyperglycemia (elevated blood sugar), and mydriasis (pupil dilation) may also appear, as well as difficulty urinating, metabolic acidosis, and renal failure.

  • Unknown frequency

Dermatological eruptions, hemolytic anemia, cutaneous allergic manifestations (pruritus, urticaria), allergic reactions (hypersensitivity), general malaise, headache

If you consider adverse effects, consult your doctor, pharmacist, or nurse, even if they do not appear in this prospectus.

5. Conservation of Epistaxol

Keep this medication out of the sight and reach of children.

Do not use this medication after the expiration date that appears on the packaging after CAD. The expiration date is the last day of the month indicated.

No special storage conditions are required. Store in the original packaging.

Medications should not be disposed of through drains or in the trash. Dispose of packaging and medications you no longer need at the SIGRE point of your pharmacy. If in doubt, ask your pharmacist how to dispose of unused packaging and medications. By doing so, you will help protect the environment.

6. Contents of the packaging and additional information

Composition of Epistaxol

  • The active principles are epinephrine hydrochloride, rutósido, nafazolina hydrochloride, and phenazone. One milliliter of solution contains 0.5 mg of epinephrine hydrochloride, 0.2 mg of rutósido, 0.5 mg of nafazolina hydrochloride, and 30 mg of phenazone.
  • The other components are sodium metabisulphite (E-223), chlorobutanol, and purified water.

Appearance of the product and contents of the packaging

Epistaxol is a transparent and colorless or slightly yellowish solution, presented in a polyethylene bottle containing 10 ml of product.

Holder of the marketing authorization and responsible for manufacturing

Holder of the marketing authorization

Medical, S.A.

Pol. Ind. Las Quemadas, Parcela 87

14014 - Córdoba.

Responsible for manufacturing

Laboratorio Generfarma, S.L.

Ronda Isaac Peral, 6 (Parque Tecnológico)

46980 – Paterna. Valencia.

Last review date of this leaflet: October/2012.

“Detailed and updated information on this medication is available on the website of the Spanish Agency for Medicines and Medical Devices (AEMPS) http://www.aemps.gob.es/”

Online doctors for Epistaxol solución cutánea

Discuss questions about Epistaxol solución cutánea, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
Doctor
5.0(12)

Yevgen Yakovenko

General medicine12 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment
€72
Doctor
5.0(3)

Lina Travkina

General medicine13 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.

  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.

  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.

  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.

  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.

  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.

  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.

  • Medical advice and follow-up consultations.

  • Test interpretation and diagnostic guidance.

  • Structured support for undiagnosed complaints.

  • Second opinion on diagnoses and treatment plans.

  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.

  • Post-operative recovery support and pain management.

  • Preconception counselling and postpartum support.

  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Book a video appointment
€75
Doctor
5.0(21)

Nuno Tavares Lopes

General medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies

  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management

  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses

  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment

  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance

  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis

  • Pain management: acute and chronic pain, post-surgical care

  • Public health: prevention, health screenings, long-term monitoring

  • Sick leave (Baixa médica) connected to Segurança Social in Portugal

  • IMT medical certificates for driving licence exchange

Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Book a video appointment
€70
Doctor
0.0(0)

Hocine Lokchiri

General medicine21 years of experience

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
Book a video appointment
€64

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Frequently Asked Questions

Epistaxol solución cutánea does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

The active ingredient in Epistaxol solución cutánea is combinations. This information helps identify medicines with the same composition but different brand names.

Epistaxol solución cutánea is manufactured by Medical S.A.. Pharmacy brands and packaging may differ depending on the distributor.

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether Epistaxol solución cutánea is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy Epistaxol solución cutánea in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

Other medicines with the same active substance (combinations) include ARTISS Tissue Adhesive Solution, Ultracold, EVICEL Tissue Adhesive Solution, TACHOSIL Adhesive Matrix. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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