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DIFUR 120 mg HARD CAPSULES

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use DIFUR 120 mg HARD CAPSULES

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

PATIENT INFORMATION: SUMMARY OF PRODUCT CHARACTERISTICS

Difur 120 mg hard capsules

Dry extract of Polypodium leucotomos L.

Read the entire summary of product characteristics carefully before starting to take this medication, as it contains important information for you.

This medication can be obtained without a prescription. Nevertheless, to achieve the best results, it should be used properly.

Follow the administration instructions for the medication contained in this summary or as indicated by your doctor or pharmacist.

  • Keep this summary, as you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience adverse effects, consult your doctor, pharmacist, or nurse, even if they are not described in this summary.

You should consult a doctor if your condition worsens or does not improve after 14 days of treatment.

Contents of the summary:

  1. What Difur 120 mg hard capsules are and what they are used for
  2. What you need to know before taking Difur 120 mg hard capsules
  3. How to take Difur 120 mg hard capsules
  4. Possible side effects
  5. Storage of Difur 120 mg hard capsules
  6. Package contents and additional information

1. What Difur 120 mg hard capsules are and what they are used for

Difur is a traditional herbal medicinal product for the relief of symptoms associated with mild to moderate inflammatory processes of the skin, based exclusively on its traditional use.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. Before taking Difur 120 mg hard capsules

Do not take Difur 120 mg hard capsules

If you are allergic (hypersensitive) to the extract of Polypodium leucotomosL. or to any of the other components of the medication.

Warnings and precautions

Consult your doctor or pharmacist before using any medication.

In case of fever, infectious diseases, hypertension, or heart failure, consult your doctor before taking the medication.

Use in children

The use of the medication is not recommended in children under 6 years of age due to the lack of sufficient clinical information to support its safe and effective use.

Children from 6 to 12 years: Consult your doctor before starting treatment so that they can assess the clinical situation.

Use of Difur 120 mg hard capsules with other medications

Inform your doctor or pharmacist if you are using or have recently used other medications, including those obtained without a prescription.

Taking Difur 120 mg hard capsules with food and beverages

Difur should be taken 30 minutes before meals, avoiding the ingestion of food or medications that reduce stomach acidity or alcoholic beverages at the same time, as they may decrease its effect.

Pregnancy and breastfeeding

Safety during pregnancy and breastfeeding has not been established. As a precautionary measure, its administration is not recommended to women during pregnancy or breastfeeding.

Driving and using machines

The effect of Difur on the ability to drive and use machines is nil or insignificant.

Important information about some of the components of Difur 120 mg hard capsules

This medication contains lactose. If your doctor has indicated that you have an intolerance to certain sugars, consult with them before taking this medication.

3. How to take Difur 120 mg hard capsules

It is a medication for oral use.

Follow the administration instructions for the medication contained in this summary or as indicated by your doctor or pharmacist. In case of doubt, consult your doctor or pharmacist.

Dosage

Use in adults and adolescents:The recommended dose is 1 capsule (120 mg)/3 times a day, which is equivalent to 360 mg of Polypodium leucotomosextract per day.

If necessary, an additional capsule may be administered, preferably at night.

The recommended treatment duration is 4 weeks. After this period, consult your doctor about the convenience of continuing it.

Use in children from 6 to 12 years:

The recommended dose is 120 mg (1 capsule)/2 times a day, which is equivalent to 240 mg of Polypodium leucotomosextract per day.

If symptoms persist or worsen two weeks after starting treatment, consult your doctor.

Method of administration

Difur is administered orally.

Take the capsules 30 minutes before each main meal, whole, with the help of some liquid.

If you take more Difur 120 mg hard capsules than you should

If you have taken more Difur 120 mg hard capsules than you should, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone 91 562 04 20, indicating the medication and the amount ingested.

If you forget to take Difur 120 mg hard capsules

Do not take a double dose to make up for forgotten doses.

If you have any other doubts about the use of this product, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medications, Difur can cause side effects, although not all people experience them.

With a very rare frequency (affecting less than 1 in 10,000 patients), stomach discomfort, skin rash, and itching may appear.

If you experience side effects, consult your doctor, pharmacist, or nurse, even if they are not described in this summary.

5. Storage of Difur 120 mg hard capsules

No special storage conditions are required.

Keep out of sight and reach of children.

Do not use Difur 120 mg hard capsules after the expiration date shown on the packaging. The expiration date is the last day of the month indicated.

Medications should not be disposed of through wastewater or household waste. Ask your pharmacist how to dispose of the packaging and medications you no longer need. This will help protect the environment.

6. Additional information

Composition of Difur 120 mg hard capsules

  • The active ingredient is the extract of Polypodium leucotomos L.. Each hard capsule contains 120 mg of dry extract of Polypodium leucotomos Lrhizome (native DER 4-6:1) corresponding to 2.5-6.25 mg of quinic acid. Extraction solvent: Ethanol 12.5% V/V.

The other components are: Capsule content: cornstarch, anhydrous lactose, and magnesium stearate (E-572). Capsule shell: gelatin, erythrosine (E-127), quinoline yellow (E-104), and titanium dioxide (E-171).

Appearance of the product and package contents

Difur is presented in the form of hard gelatin capsules, with an orange cap and a white body, packaged in PVC-aluminum blisters, in packages containing 24 or 96 capsules.

Marketing authorization holder:

Industrial Farmacéutica Cantabria, S.A.

Barrio Solia 30

La Concha de Villaescusa

39690 Cantabria (Spain)

Manufacturer:

Toll Manufacturing Services, S.L.

Aragoneses nº 2,

28108 Alcobendas (Madrid) - Spain

or

Industrial Farmacéutica Cantabria, S.A.

C/Pirita, 9. - Torrejón de Ardoz

28850 (Madrid)

Spain

This summary was approved in March 2022

“Detailed and updated information about this medication is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS)http://www.aemps.gob.es/

Online doctors for DIFUR 120 mg HARD CAPSULES

Discuss questions about DIFUR 120 mg HARD CAPSULES, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (1061)
Doctor

Andrei Popov

General medicine 7 years exp.

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

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5.0 (184)
Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
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  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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€50
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Doctor

Joao Silva

General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

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€55
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Doctor

Bulat Garipov

General medicine 15 years exp.

Dr. Bulat Garipov is a radiologist with more than 15 years of experience, specializing in magnetic resonance imaging (MRI). Throughout his professional career, he has worked in leading diagnostic imaging centers, both in on-site practice and teleradiology, which has allowed him to develop a broad and versatile approach to radiology.

Over the years, he has gained solid experience in interpreting MRI studies in various areas, including:

  •  Neuroimaging
  •  Musculoskeletal system (MSK)
  •  Angiography
  •  Abdomen and pelvis
  •  Soft tissues

Additionally, Dr. Garipov is open to new collaboration opportunities in radiology and teleradiology projects. He offers his expertise in MRI, providing both first and second readings of studies, as well as advanced image interpretation, ensuring accurate and high-quality diagnostics.

You could consult Dr. Bulat Garipov in cases where accurate interpretation of MRI studies or a second expert opinion is required. His expertise is especially valuable in cases of suspected neurological conditions, back and joint pain, vascular disorders, as well as in the diagnosis of abdominal and pelvic diseases. The doctor also provides support in complex or unclear clinical situations, including the review of previously performed studies, which helps improve diagnostic accuracy and determine the optimal treatment strategy. A teleradiology format is available, allowing you to receive a professional opinion remotely.

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€60
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Frequently Asked Questions

Is a prescription required for DIFUR 120 mg HARD CAPSULES?
DIFUR 120 mg HARD CAPSULES does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
Who manufactures DIFUR 120 mg HARD CAPSULES?
DIFUR 120 mg HARD CAPSULES is manufactured by Industrial Farmaceutica Cantabria S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of DIFUR 120 mg HARD CAPSULES online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether DIFUR 120 mg HARD CAPSULES is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to DIFUR 120 mg HARD CAPSULES?
Other medicines with the same active substance () include ALOCARE 1 mg FILM-COATED TABLETS, ALOCARE 2.275 mg/ml CUTANEOUS SPRAY SOLUTION, ALOCUTAN 50 mg/ml CUTANEOUS SPRAY SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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