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DIFUR 120 mg HARD CAPSULES

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About the medicine

How to use DIFUR 120 mg HARD CAPSULES

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

PATIENT INFORMATION: SUMMARY OF PRODUCT CHARACTERISTICS

Difur 120 mg hard capsules

Dry extract of Polypodium leucotomos L.

Read the entire summary of product characteristics carefully before starting to take this medication, as it contains important information for you.

This medication can be obtained without a prescription. Nevertheless, to achieve the best results, it should be used properly.

Follow the administration instructions for the medication contained in this summary or as indicated by your doctor or pharmacist.

  • Keep this summary, as you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience adverse effects, consult your doctor, pharmacist, or nurse, even if they are not described in this summary.

You should consult a doctor if your condition worsens or does not improve after 14 days of treatment.

Contents of the summary:

  1. What Difur 120 mg hard capsules are and what they are used for
  2. What you need to know before taking Difur 120 mg hard capsules
  3. How to take Difur 120 mg hard capsules
  4. Possible side effects
  5. Storage of Difur 120 mg hard capsules
  6. Package contents and additional information

1. What Difur 120 mg hard capsules are and what they are used for

Difur is a traditional herbal medicinal product for the relief of symptoms associated with mild to moderate inflammatory processes of the skin, based exclusively on its traditional use.

Doctor consultation

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2. Before taking Difur 120 mg hard capsules

Do not take Difur 120 mg hard capsules

If you are allergic (hypersensitive) to the extract of Polypodium leucotomosL. or to any of the other components of the medication.

Warnings and precautions

Consult your doctor or pharmacist before using any medication.

In case of fever, infectious diseases, hypertension, or heart failure, consult your doctor before taking the medication.

Use in children

The use of the medication is not recommended in children under 6 years of age due to the lack of sufficient clinical information to support its safe and effective use.

Children from 6 to 12 years: Consult your doctor before starting treatment so that they can assess the clinical situation.

Use of Difur 120 mg hard capsules with other medications

Inform your doctor or pharmacist if you are using or have recently used other medications, including those obtained without a prescription.

Taking Difur 120 mg hard capsules with food and beverages

Difur should be taken 30 minutes before meals, avoiding the ingestion of food or medications that reduce stomach acidity or alcoholic beverages at the same time, as they may decrease its effect.

Pregnancy and breastfeeding

Safety during pregnancy and breastfeeding has not been established. As a precautionary measure, its administration is not recommended to women during pregnancy or breastfeeding.

Driving and using machines

The effect of Difur on the ability to drive and use machines is nil or insignificant.

Important information about some of the components of Difur 120 mg hard capsules

This medication contains lactose. If your doctor has indicated that you have an intolerance to certain sugars, consult with them before taking this medication.

3. How to take Difur 120 mg hard capsules

It is a medication for oral use.

Follow the administration instructions for the medication contained in this summary or as indicated by your doctor or pharmacist. In case of doubt, consult your doctor or pharmacist.

Dosage

Use in adults and adolescents:The recommended dose is 1 capsule (120 mg)/3 times a day, which is equivalent to 360 mg of Polypodium leucotomosextract per day.

If necessary, an additional capsule may be administered, preferably at night.

The recommended treatment duration is 4 weeks. After this period, consult your doctor about the convenience of continuing it.

Use in children from 6 to 12 years:

The recommended dose is 120 mg (1 capsule)/2 times a day, which is equivalent to 240 mg of Polypodium leucotomosextract per day.

If symptoms persist or worsen two weeks after starting treatment, consult your doctor.

Method of administration

Difur is administered orally.

Take the capsules 30 minutes before each main meal, whole, with the help of some liquid.

If you take more Difur 120 mg hard capsules than you should

If you have taken more Difur 120 mg hard capsules than you should, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone 91 562 04 20, indicating the medication and the amount ingested.

If you forget to take Difur 120 mg hard capsules

Do not take a double dose to make up for forgotten doses.

If you have any other doubts about the use of this product, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medications, Difur can cause side effects, although not all people experience them.

With a very rare frequency (affecting less than 1 in 10,000 patients), stomach discomfort, skin rash, and itching may appear.

If you experience side effects, consult your doctor, pharmacist, or nurse, even if they are not described in this summary.

5. Storage of Difur 120 mg hard capsules

No special storage conditions are required.

Keep out of sight and reach of children.

Do not use Difur 120 mg hard capsules after the expiration date shown on the packaging. The expiration date is the last day of the month indicated.

Medications should not be disposed of through wastewater or household waste. Ask your pharmacist how to dispose of the packaging and medications you no longer need. This will help protect the environment.

6. Additional information

Composition of Difur 120 mg hard capsules

  • The active ingredient is the extract of Polypodium leucotomos L.. Each hard capsule contains 120 mg of dry extract of Polypodium leucotomos Lrhizome (native DER 4-6:1) corresponding to 2.5-6.25 mg of quinic acid. Extraction solvent: Ethanol 12.5% V/V.

The other components are: Capsule content: cornstarch, anhydrous lactose, and magnesium stearate (E-572). Capsule shell: gelatin, erythrosine (E-127), quinoline yellow (E-104), and titanium dioxide (E-171).

Appearance of the product and package contents

Difur is presented in the form of hard gelatin capsules, with an orange cap and a white body, packaged in PVC-aluminum blisters, in packages containing 24 or 96 capsules.

Marketing authorization holder:

Industrial Farmacéutica Cantabria, S.A.

Barrio Solia 30

La Concha de Villaescusa

39690 Cantabria (Spain)

Manufacturer:

Toll Manufacturing Services, S.L.

Aragoneses nº 2,

28108 Alcobendas (Madrid) - Spain

or

Industrial Farmacéutica Cantabria, S.A.

C/Pirita, 9. - Torrejón de Ardoz

28850 (Madrid)

Spain

This summary was approved in March 2022

“Detailed and updated information about this medication is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS)http://www.aemps.gob.es/

Online doctors for DIFUR 120 mg HARD CAPSULES

Discuss questions about DIFUR 120 mg HARD CAPSULES, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Chikeluo Okeke

General medicine 4 years exp.

Dr Chikeluo Okeke is an internal medicine doctor with extensive international clinical experience. Originally from Nigeria, he has worked across multiple European healthcare systems and currently practises in Sweden. This professional path has given him a strong understanding of different medical approaches and the ability to work effectively with patients from diverse cultural and linguistic backgrounds.

Dr Okeke focuses on general internal medicine and adult primary care, combining clinical accuracy with careful attention to lifestyle, personal context, and everyday health concerns. His consultations are particularly well suited for people who seek medical advice online, live abroad, or need clear guidance without unnecessary complexity.

He provides online consultations covering symptom assessment, prevention, and long-term management of chronic conditions, helping patients understand what is happening and decide on appropriate next steps.

Common reasons for consultation:

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Dr Okeke is known for his clear communication, calm approach, and cultural awareness. He listens carefully, explains medical decisions in a structured way, and supports patients in making informed choices about their health.

Online consultations with Dr Chikeluo Okeke offer reliable internal medicine care without geographic limitations, focused on medical relevance, clarity, and patient comfort.

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Joao Silva

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Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

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Andreea Mateescu

Paediatrics 8 years exp.

Dr Andreea Mateescu is a board-certified paediatrician with 7 years of clinical experience. She graduated from Carol Davila University of Medicine and Pharmacy in Bucharest, Romania, and completed her paediatric residency at INSMC Alessandrescu-Rusescu. She also holds additional training in general ultrasound diagnostics.

Dr Mateescu focuses on providing high-quality, evidence-based medical care for children, with a strong emphasis on prevention, healthy development, and long-term wellbeing. She believes that clear, empathetic communication with both children and parents is essential for building trust and ensuring effective care.

Online consultations with Dr Mateescu are suitable for:

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Dr Mateescu works with patience, empathy, and professionalism, ensuring that each child receives attentive, individualised care. Her goal is to support healthy, balanced development while helping parents feel confident and well-informed at every stage of their child’s care.
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Yevgen Yakovenko

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Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

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Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
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If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Daniel Cichi

Family medicine 24 years exp.

Dr Daniel Cichi is a family medicine doctor with over 20 years of clinical experience. He provides online consultations for adults, supporting patients with acute symptoms, chronic conditions, and everyday health concerns that require timely medical guidance. His background includes work in emergency care, ambulance services, and family medicine, which allows him to assess symptoms quickly, identify warning signs, and help patients choose the safest next steps – whether that means home care, treatment adjustment, or in-person evaluation. Patients commonly consult Dr Daniel Cichi for: 

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Dr Cichi’s consultations are structured and practical. He focuses on clear explanations, risk assessment, and actionable recommendations, helping patients understand their symptoms and make informed decisions about their health.

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Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

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Additional care areas:

  • Preventive consultations and check-up planning.
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Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
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  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
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  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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Frequently Asked Questions

Is a prescription required for DIFUR 120 mg HARD CAPSULES?
DIFUR 120 mg HARD CAPSULES does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
Who manufactures DIFUR 120 mg HARD CAPSULES?
DIFUR 120 mg HARD CAPSULES is manufactured by Industrial Farmaceutica Cantabria S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of DIFUR 120 mg HARD CAPSULES online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether DIFUR 120 mg HARD CAPSULES is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to DIFUR 120 mg HARD CAPSULES?
Other medicines with the same active substance () include ALOCARE 1 mg FILM-COATED TABLETS, ALOCARE 2.275 mg/ml CUTANEOUS SPRAY SOLUTION, ALOCUTAN 50 mg/ml CUTANEOUS SPRAY SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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