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ACYLINE 620 mg/380 mg/630 mg ORAL SUSPENSION

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About the medicine

How to use ACYLINE 620 mg/380 mg/630 mg ORAL SUSPENSION

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Acyline620 mg/380 mg/630 mgOral Suspension

Algeldrate, magnesium hydroxide, aluminum hydroxide-magnesium carbonate, coprecipitate

Read the entire package leaflet carefully before starting to take this medication, as it contains important information for you.

Follow the administration instructions for the medication contained in this package leaflet or as indicated by your doctor or pharmacist.

  • Keep this package leaflet, as you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience side effects, consult your doctor or pharmacist, even if they are side effects not listed in this package leaflet. See section 4.
  • You should consult a doctor if your symptoms worsen or do not improve after 14 days.

Contents of the Package Leaflet

  1. What is ACYLINE and what is it used for
  2. What you need to know before taking ACYLINE
  3. How to take ACYLINE
  4. Possible side effects
  5. Storage of ACYLINE
  6. Package Contents and Additional Information

1. What is ACYLINE and what is it used for

ACYLINE contains algeldrate, magnesium hydroxide, and aluminum hydroxide-magnesium carbonate, coprecipitate. It belongs to the group of medications called antacids, which act by neutralizing excess stomach acid.

ACYLINE is indicated for the relief and symptomatic treatment of heartburn and stomach acid in adults and children over 12 years old.

You should consult a doctor if your symptoms worsen or do not improve after 14 days.

Doctor consultation

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Discuss your symptoms and treatment with a doctor online.

2. What you need to know before taking ACYLINE

Do not take ACYLINE:

  • If you are allergic to aluminum hydroxide, magnesium hydroxide, or aluminum hydroxide-magnesium carbonate coprecipitate, or any other component of this medication (listed in section 6).
  • If you have symptoms of appendicitis, obstruction, or intestinal inflammation, such as abdominal pain, cramps, bloating, painful sensation, nausea, or vomiting.
  • If you have severe kidney failure.
  • If you have unexplained gastrointestinal or rectal bleeding.
  • If you have hypermagnesemia (high magnesium levels in the blood).
  • If you have alkalosis (alteration of the acid-base balance in the blood).

Warnings and Precautions

Consult your doctor or pharmacist before starting to take ACYLINE.

As with other antacids, this medication may mask symptoms of a more serious stomach disease, such as a peptic ulcer or a malignant process. If symptoms persist or worsen after 14 days of treatment, you should consult your doctor.

If you follow a low-phosphorus diet, have diarrhea, malabsorption, or have undergone a kidney transplant, prolonged treatment may lead to a decrease in phosphate levels in the blood (loss of appetite, muscle weakness, general malaise, etc.) accompanied by bone alterations (osteomalacia).

At high doses, this medication could cause or worsen intestinal obstruction, especially in patients with kidney disease, intestinal disorders, and elderly patients.

If you have kidney disease (renal insufficiency) of mild to moderate severity and need to take this medication, you should do so with caution, avoiding prolonged use, as it may lead to: alterations in the central nervous system, decreased red blood cell count, or worsening of bone diseases.

The use of antacids containing aluminum is not recommended in patients with Alzheimer's disease, as it may contribute to the development of the disease.

In elderly patients, the continued use of antacids containing aluminum may exacerbate existing bone diseases.

If you have porphyria (a group of inherited disorders that involve abnormalities in the production of red blood cell pigment) and are undergoing hemodialysis (a process to remove waste from the blood when the kidneys are unable to do so), you should consult your doctor before taking this medication.

You should inform your doctor of the appearance of any symptoms that may indicate bleeding, such as black stools or vomit resembling coffee grounds.

Interference with Diagnostic Tests

If you are going to undergo any diagnostic tests (including blood tests, urine tests, or tests with radiopharmaceuticals), inform your doctor that you are taking this medication, as it may alter the results.

If you are going to undergo a test to evaluate gastric acid secretory function, you should not take antacids on the same morning as the test.

Children

The use of antacids is not recommended in children under 12 years old, as it may mask symptoms of other existing diseases (e.g., appendicitis). In young children, there is a risk of increased magnesium levels in the blood or aluminum toxicity, especially if they are dehydrated or have kidney disease.

Taking ACYLINE with Other Medications

Inform your doctor or pharmacist if you are taking, have recently taken, or may need to take any other medication.

Antacids may alter the action of other medications, so you should separate the administration of any antacid from other medications.

It is essential to inform your doctor if you are taking any of the following medications:

  • H2 antagonists (medications used to treat digestive problems)
  • Atenolol, propranolol, metoprolol (medications used to treat heart problems and hypertension)
  • Chloroquines (used to treat malaria)
  • Diflunisal (non-steroidal anti-inflammatory)
  • Bisphosphonates (used to treat osteoporosis)
  • Antibiotics (lincosamides, tetracyclines, fluoroquinolones, azithromycin, cefdinir, cefpodoxime)
  • Ketoconazole (used to treat fungal infections)
  • Penicillamine (used to treat rheumatic diseases)
  • Kayexalate (used to treat high potassium levels in the blood)
  • Digoxin (used to treat heart problems)
  • Ethambutol, isoniazid, rifampicin (used to treat tuberculosis)
  • Sodium fluoride (disinfectant)
  • Glucocorticoids (prednisone)
  • Indomethacin (non-steroidal anti-inflammatory)
  • Neuroleptics (used to treat mental disorders)
  • Iron salts (used to treat anemia)
  • Medications for hypertension (captopril, fosinopril)
  • Levothyroxine (used to treat thyroid problems)
  • Rosuvastatin (used to reduce cholesterol levels in the blood)
  • Methenamine (used to eliminate bacteria from the urinary tract)
  • Mecamylamine (used to reduce blood pressure)
  • Phenytoin (used to treat seizures)
  • Amphetamines (used as a potent central nervous system stimulant)
  • Sodium cellulose phosphate (used to prevent kidney stone formation)
  • Quinidines (medications used to treat heart problems)
  • Citrate salts (used to treat kidney stones and other kidney problems, dehydration, diarrhea)
  • Salicylates (acetylsalicylic acid, used to treat inflammation, pain, and fever)
  • Sucralfate (medication used to treat ulcers)

In all these cases, it is recommended to wait 2 hours between taking any of these medications and taking ACYLINE (4 hours in the case of fluoroquinolones) to avoid unwanted interactions.

Antacids can destroy the coating of some oral medications.

Pregnancy and Breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medication.

Taking this medication during pregnancy may be hazardous to the embryo or fetus and should be monitored by your doctor.

Chronic or excessive use of ACYLINE during pregnancy is not recommended.

Driving and Using Machines

ACYLINE does not affect the ability to drive or operate machinery.

ACYLINE ContainsEthanol (96 Percent)

This medication contains 0.6% ethanol (96 percent), which corresponds to 60 mg per dose, equivalent to 1.2 ml of beer or 0.5 ml of wine.

This medication is harmful to people with alcoholism.

The alcohol content should be taken into account in the case of pregnant or breastfeeding women, children, and high-risk groups, such as patients with liver disease or epilepsy.

3. How to Take ACYLINE

Follow the administration instructions for ACYLINE contained in this package leaflet or as indicated by your doctor or pharmacist. If in doubt, ask your doctor or pharmacist.

The recommended dose in adults and children over 12 years old is 1/2 to 1 sachet of oral suspension (5ml to 10ml) four times a day, when symptoms appear, 20 minutes to 1 hour after the three main meals and before bedtime.

Use in Children

Do not administer this medication to children under 12 years old.

This medication is taken orally.

Press the sachet several times before opening to ensure complete homogenization of the suspension. ACYLINE can be taken directly from the sachet or the contents can be poured into a half glass of water. Stir and take immediately

Do not take more than 4 sachets per day.

If symptoms do not improve within 14 days, you should discontinue treatment and consult your doctor

If You Take More ACYLINE Than You Should

At the recommended doses, intoxication with this medication is unlikely.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone: 91 562 04 20, indicating the medication and the amount ingested.

It is recommended to take the packaging and package leaflet of the medication to the healthcare professional.

If You Forget to TakeACYLINE

Do not take a double dose to make up for forgotten doses.

If you have any other doubts about the use of this medication, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible Side Effects

Like all medications, this medication can cause side effects, although not everyone will experience them.

The observed side effects are generally mild and transient.

If you experience the following side effects, stop taking the medication and consult your doctor: allergic reactions such as pruritus (itching), urticaria (hives, skin irritation, and itching), angioedema (generalized urticaria accompanied by inflammation of the feet, hands, throat, lips, and respiratory tract), these adverse reactions are of unknown frequency (cannot be estimated from available data).

Other side effects that may appear are:

  • Uncommon (may affect up to 1 in 100 patients): constipation, diarrhea, or regurgitation.
  • Frequency not known (cannot be estimated from available data):
  • Hypermagnesemia (high magnesium levels in the blood)
  • Hyperaluminemia (high aluminum levels in the blood)
  • Hypophosphatemia (low phosphate levels in the blood).

In cases of prolonged use or in patients with poor diets, kidney stones and bone diseases may appear.

Reporting Side Effects:If you experience any type of side effect, consult your doctor or pharmacist, even if it is a possible side effect not listed in this package leaflet. You can also report them directly through the Spanish Medicines and Health Products Agency's (AEMPS) website: https://www.notificaram.es. By reporting side effects, you can contribute to providing more information on the safety of this medication.

5. Storage of ACYLINE

Keep this medication out of the sight and reach of children.

Do not use this medication after the expiration date stated on the packaging after CAD. The expiration date is the last day of the month indicated.

No special storage conditions are required.

Do not use ACYLINE if you notice visible signs of deterioration.

Medications should not be disposed of through wastewater or household waste. Deposit the packaging and medications you no longer need in the pharmacy's SIGRE collection point. If in doubt, ask your pharmacist how to dispose of the packaging and medications you no longer need. This will help protect the environment.

6. Package Contents and Additional Information

Composition of ACYLINE

The active ingredients are: Algeldrate 620 mg, Magnesium hydroxide 380 mg, Aluminum hydroxide-magnesium carbonate, coprecipitate 630 mg.

The other ingredients (excipients) are: Sucralose (E-955), Ethanol (96 percent), Chlorhexidine acetate, Hydroxyethylcellulose, Peppermint flavor, and Purified water. See section 2 "ACYLINE contains ethanol (96 percent)"

Appearance of the Product and Package Contents

ACYLINE is presented as a white oral suspension.

Each package contains 20 sachets with 10 ml of suspension

Marketing Authorization Holder and Manufacturer

ARAFARMA GROUP S.A.

C/ Fray Gabriel de San Antonio 6-10

Pol. Ind. Henares

19180 Marchamalo, Guadalajara

Email: [email protected]

Phone: 949 22 56 22

Date of the Last Revision of this Package Leaflet: March 2014

Detailed and updated information on this medication is available on the website of the Spanish Medicines and Health Products Agency (AEMPS) http://www.aemps.gob.es/

Online doctors for ACYLINE 620 mg/380 mg/630 mg ORAL SUSPENSION

Discuss questions about ACYLINE 620 mg/380 mg/630 mg ORAL SUSPENSION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (3)
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Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
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  • asthma and breathing difficulties
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  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
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  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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Doctor

Alina Tsurkan

Family medicine 13 years exp.

Dr. Alina Tsurkan is a licensed family medicine physician based in Portugal, offering online consultations for adults and children. She provides professional primary care, with a focus on prevention, accurate diagnosis, and long-term management of acute and chronic conditions.

Dr. Tsurkan supports patients with a wide range of health issues, including:

  • Respiratory infections: cold, flu, bronchitis, pneumonia, and lingering coughs.
  • ENT conditions: sinusitis, tonsillitis, otitis (ear infections), sore throat, allergic rhinitis.
  • Eye conditions: allergic or infectious conjunctivitis, red eyes, irritation.
  • Digestive issues: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), constipation, bloating, nausea.
  • Urinary and reproductive health: urinary tract infections (UTIs), cystitis, prevention of recurrent infections.
  • Chronic diseases: hypertension, elevated cholesterol, weight management.
  • Neurological complaints: headaches, migraines, sleep disturbances, fatigue, general weakness.
  • Children’s health: fever, infections, digestive issues, follow-ups, vaccination guidance.

She also provides:

  • IMT medical certificates for driving licence exchange in Portugal.
  • Personalised preventive care and wellness consultations.
  • Interpretation of test results and medical reports.
  • Follow-up care and medication review.
  • Support in managing multiple coexisting conditions.
  • Remote prescription management and medical documentation.

Dr. Tsurkan’s approach is evidence-based and holistic. She works closely with each patient to develop an individualised care plan that addresses both symptoms and root causes. Her goal is to empower patients to take control of their health and maintain well-being through lifestyle adjustments, routine check-ups, and early intervention.

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Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
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  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Frequently Asked Questions

Is a prescription required for ACYLINE 620 mg/380 mg/630 mg ORAL SUSPENSION?
ACYLINE 620 mg/380 mg/630 mg ORAL SUSPENSION does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in ACYLINE 620 mg/380 mg/630 mg ORAL SUSPENSION?
The active ingredient in ACYLINE 620 mg/380 mg/630 mg ORAL SUSPENSION is ordinary salt combinations. This information helps identify medicines with the same composition but different brand names.
Who manufactures ACYLINE 620 mg/380 mg/630 mg ORAL SUSPENSION?
ACYLINE 620 mg/380 mg/630 mg ORAL SUSPENSION is manufactured by Arafarma Group S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of ACYLINE 620 mg/380 mg/630 mg ORAL SUSPENSION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether ACYLINE 620 mg/380 mg/630 mg ORAL SUSPENSION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to ACYLINE 620 mg/380 mg/630 mg ORAL SUSPENSION?
Other medicines with the same active substance (ordinary salt combinations) include RENNIE 680 MG/80 MG CHEWABLE TABLETS WITH SACCHARIN, RENNIE 680 MG/80 MG CHEWABLE TABLETS WITH SUCROSE, ALMAGATO STADAPHARM 1.5 G ORAL SUSPENSION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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