Gilbert's syndrome

Gilbert's syndrome is a common genetic condition that may cause mild jaundice (yellowing of the skin and whites of the eyes) that comes and goes. It does not usually need any treatment.

Symptoms of Gilbert's syndrome

The most common symptom of Gilbert's syndrome is mild episodes of jaundice (yellowing of the skin and the whites of the eyes) that comes and goes.

The yellowing of the skin may be less noticeable if you have brown or black skin, but it may be easier to see jaundice in the white part of your eyes.

Jaundice can also cause itchy skin, darker pee and paler poo than usual.

However, many people with Gilbert's syndrome do not have any symptoms.

How Gilbert's syndrome is diagnosed

Gilbert's syndrome can be diagnosed with blood tests, including a test to check how well your liver is working.

A genetic test is sometimes needed to confirm the diagnosis.

As Gilbert's syndrome may not cause any symptoms, some people only find out they have it during tests for something else.

Things you can try to help with Gilbert's syndrome

You will not need any medical treatment for Gilbert's syndrome as it does not affect your health.

However, there are things you can try to help prevent jaundice.

 Do 

• keep a record of your jaundice and try to avoid things that trigger it – for example, over-exercising, not getting enough sleep, drinking alcohol or not drinking enough fluids
• speak to a GP or pharmacist before taking any new medicines – you may need to be more closely monitored while taking certain medicines, such as statins for high cholesterol

Causes of Gilbert's syndrome

Gilbert's syndrome is caused by an altered gene being passed on to a child by their parents (inherited).

This affects your liver and causes a substance called bilirubin to build up in your bloodstream. This can turn your skin and the whites of your eyes yellow.

Gilbert's syndrome is more common in men and people with type 1 diabetes.

How Gilbert's syndrome affects your life

There is currently no cure for Gilbert's syndrome, but it does not affect your health or cause any damage to your liver.

It does not affect how long you'll live.

You may have a slightly increased risk of gallstones, but it does not increase your risk of any other conditions.