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VIVIDRIN 0.5 mg/ml EYE DROPS SOLUTION

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About the medicine

How to use VIVIDRIN 0.5 mg/ml EYE DROPS SOLUTION

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the Patient

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Vividrin 0.5 mg/ml Eye Drops Solution

azelastine hydrochloride

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  • Keep this package leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others, as it may harm them, even if their symptoms are the same as yours.
  • If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this package leaflet. See section 4.
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Contents of the Package Leaflet

  1. What is Vividrin and what is it used for
  2. What you need to know before you use Vividrin
  3. How to use Vividrin
  4. Possible side effects
  5. Storage of Vividrin
  6. Contents of the pack and further information

1. What is Vividrin and what is it used for

Vividrin contains the active substance azelastine hydrochloride, which belongs to a group of medicines called antiallergics (antihistamines). Antihistamines prevent the effects of substances such as histamine, which the body produces as part of an allergic reaction. Azelastine has been shown to reduce ocular inflammation.

This medicine can be used for the treatment and prevention of ocular disorders caused by hay fever (seasonal allergic conjunctivitis, which manifests with redness, itching of the eyes or tearing) in adults and children from 4 years of age.

Vividrin can be used for ocular disorders caused by allergy to dust mites or animal hair (perennial allergic conjunctivitis) in adults and children from 12 years of age.

This medicine is a preservative-free solution.

2. What you need to know before you use Vividrin

Do not use Vividrin:

  • If you are allergic to azelastine hydrochloride or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions

Consult your doctor or pharmacist before starting to use this medicine:

  • If you are not sure that your eye symptoms are caused by an allergy. In particular, if they only affect one eye, if your vision has worsened or if you have eye pain and no nasal symptoms, as it may be an infection rather than an allergy.
  • If symptoms worsen or last more than 48 hours without significant improvement, despite using this medicine.
  • If you wear contact lenses.

This medicine is not intended for the treatment of eye infections.

Children and adolescents

For the treatment of ocular disorders caused by hay fever (seasonal allergic conjunctivitis):

Do not give this medicine to children under 4 years of age, as its safety and efficacy have not been established.

For the treatment of ocular disorders caused by allergy (perennial allergic conjunctivitis):

Do not give this medicine to children under 12 years of age, as its safety and efficacy have not been established.

Other medicines and Vividrin

Although it is not known if Vividrin can be affected by other medicines, inform your doctor or pharmacist if you are using, have recently used, or may need to use any other medicine.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

Driving and using machines

You may experience blurred vision for a short time when using Vividrin. If this happens, wait until your vision is clear before driving or using machinery.

Remove your contact lenses before applying the eye drops and wait at least 15 minutes before putting them back in.

3. How to use Vividrin

Follow the instructions for administration of this medicine exactly as indicated by your doctor or pharmacist. If you are unsure, ask your doctor or pharmacist.

Remember

  • Vividrin should only be applied to the eyes.

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•Use in adults and children from 4 years of age.

•The usual dose is one drop in each eye, in the morning and at night.

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•Use in adults and children from 12 years of age.

•The usual dose is one drop in each eye, in the morning and at night.

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How to use Vividrin eye drops

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When you are about to use these eye drops, wash your hands well before opening the container and follow these steps:

  • Before the first instillation in the eye

Vial with rubber stopper held by a hand while inserting a needle with bevel towards the center

  1. Remove the safety ring.

Adapter connected to a vial with a hand holding it and an arrow indicating direction of extraction

  1. Remove the protective cap.
  • To instill the eye drops in solution
    1. Hold the container upside down. Press firmly on the center of the container to instill 1 or 2 drops.

If you are unable to instill the product, repeat steps A2 and B1

Hand applying a drop of liquid to the open eye of a person with the lower finger retracted

Gently pull the lower eyelid down while looking up, place the container over the eye, and press gradually on the center of the container until the drop falls.

Avoid the tip of the container coming into contact with the eye and eyelids.

Curved needle being inserted into upper eyelid with an arrow indicating direction of movement

  1. Blink once to spread the drop over the entire surface of the eye.

With the eye still closed, clean up any excess.

To reduce possible systemic absorption, it is recommended to press with your finger on the inner corner of the eye for 2 minutes after each instillation while keeping the eye closed.

  • After each instillation

Auto-injector device with an arrow pointing upwards and a hand pressing the lateral button

To eliminate residual drops:

  1. Hold the container by the center, keeping it vertical.

Hand holding an auto-injector pressing against the thigh with an arrow indicating direction of injection

  1. Tilt the container quickly downwards with enough force for the residual drop to be expelled.
  1. Replace the protective cap.

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If you forget to use Vividrin

Use the eye drops as soon as you remember and apply the next dose at the usual time.

Do not apply a double dose to make up for the forgotten dose.

If you have any further questions about the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

These effects include:

  • Common (may affect up to 1 in 10 people): mild irritation (stinging, itching, tearing) in the eyes after using this medicine. These effects should not last long.
  • Uncommon (may affect up to 1 in 100 people): bitter taste in the mouth. This effect should disappear quickly, especially if you take a drink.
  • Rare (may affect up to 1 in 10,000 people): allergic reaction (such as rash and itching).

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this package leaflet.

You can also report side effects directly to the Spanish Medicines Agency's Pharmacovigilance System for Human Use: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Vividrin

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the label and carton. The expiry date is the last day of the month stated.

Do not store above 25°C.

Do not freeze.

After opening:Do not use this medicine if the bottle was opened more than 3 months ago. This medicine should not be stored above 25°C.

Medicines should not be disposed of via wastewater or household waste. Return the containers and any unused medicines to a pharmacy for disposal. This will help protect the environment.

6. Contents of the pack and further information

Composition of Vividrin

Each milliliter contains 0.5 mg/ml of azelastine hydrochloride. Each drop contains 0.0216 mg of azelastine hydrochloride.

The other ingredients are sorbitol, hypromellose, disodium edetate, sodium hydroxide, and purified water.

Appearance of the product and contents of the pack

Vividrin is a clear solution.

Vividrin is presented in a plastic bottle with a dispenser system and a cap. One bottle contains 10 ml of solution.

Marketing authorisation holder and manufacturer

Marketing authorisation holder

Bausch + Lomb Ireland Limited

3013 Lake Drive

Citywest Business Campus

Dublin 24, D24PPT3

Ireland

Manufacturer

Laboratoire Chauvin

Zone Industrielle De Ripotier

50 Avenue Jean Monnet

07200 Aubenas

France

You can obtain further information on this medicine by contacting the local representative of the marketing authorisation holder:

Bausch & Lomb S.A.

Avda. Valdelaparra, nº 4

28108 Alcobendas

Madrid, Spain.

Tel: 91 – 657 63 00

This medicine is authorised in the Member States of the EEA under the following names

Germany: Vividrin Azelastin MDO 0,5 mg/ml Augentropfen, Lösung

Austria: Vividrin Azelastin MDO 0,5 mg/ml Augentropfen, Lösung

Czech Republic: Ocuazel

Spain: Vividrin 0,5 mg/ml colirio en solución

Croatia: Vivialle 0,5 mg/ml kapi za oko, otopina

Hungary: Vivialle 0,5 mg/ml oldatos szemcsepp

Italy: Vividrin occhi 0,5 mg/ml collirio, soluzione

Poland: Azel-Drop Free

Portugal: Vivilin, 0.5 mg/ml Colírio, Solução

Slovakia: Ocuazel

Date of last revision of this package leaflet: February 2025

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) (http://www.aemps.gob.es/).

Online doctors for VIVIDRIN 0.5 mg/ml EYE DROPS SOLUTION

Discuss questions about VIVIDRIN 0.5 mg/ml EYE DROPS SOLUTION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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€80
5.0 (29)
Doctor

Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
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  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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5.0 (2)
Doctor

Svetlana Kolomeeva

Cardiology 18 years exp.

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

  • High blood pressure, headaches, dizziness, swelling, palpitations.
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  • Metabolic syndrome, excess weight, high cholesterol.
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  • Respiratory symptoms: colds, flu, sore throat, cough, fever.
  • Digestive issues: heartburn, bloating, constipation, IBS symptoms.
  • Chronic conditions: diabetes, thyroid disorders.
  • Interpretation of lab tests and medical reports, therapy adjustment.
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  • Cardiovascular disease prevention and metabolic risk reduction.
  • Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

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Frequently Asked Questions

Is a prescription required for VIVIDRIN 0.5 mg/ml EYE DROPS SOLUTION?
VIVIDRIN 0.5 mg/ml EYE DROPS SOLUTION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in VIVIDRIN 0.5 mg/ml EYE DROPS SOLUTION?
The active ingredient in VIVIDRIN 0.5 mg/ml EYE DROPS SOLUTION is azelastine. This information helps identify medicines with the same composition but different brand names.
Who manufactures VIVIDRIN 0.5 mg/ml EYE DROPS SOLUTION?
VIVIDRIN 0.5 mg/ml EYE DROPS SOLUTION is manufactured by Bausch + Lomb Ireland Limited. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of VIVIDRIN 0.5 mg/ml EYE DROPS SOLUTION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether VIVIDRIN 0.5 mg/ml EYE DROPS SOLUTION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to VIVIDRIN 0.5 mg/ml EYE DROPS SOLUTION?
Other medicines with the same active substance (azelastine) include AFLUON 0.5 mg/ml EYE DROPS SOLUTION, AZELASTINE ABAMED 0.5 mg/ml EYE DROPS SOLUTION, AZELASTINE MABO 0.5 mg/ml EYE DROPS SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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