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RESOLOR 1 mg FILM-COATED TABLETS

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About the medicine

How to use RESOLOR 1 mg FILM-COATED TABLETS

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Resolor 1 mg film-coated tablets

Resolor 2 mg film-coated tablets

prucalopride

Read the entire package leaflet carefully before starting to take this medicine because it contains important information for you.

  • Keep this package leaflet, as you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this package leaflet. See section 4.

Contents of the package leaflet:

  1. What is Resolor and what is it used for
  2. What you need to know before taking Resolor
  3. How to take Resolor
  4. Possible side effects
  5. Storage of Resolor
  6. Contents of the pack and further information

1. What is Resolor and what is it used for

Resolor contains the active substance prucalopride.

Resolor belongs to a group of medicines that enhance intestinal motility (gastrointestinal prokinetics). It acts on the muscular wall of the intestine, helping to restore its normal functioning. Resolor is used for the treatment of chronic constipation in adults for whom laxatives do not work sufficiently.

It must not be used in children or adolescents under 18 years of age.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before taking Resolor

Do not take Resolor:

  • if you are allergic to prucalopride or any of the other ingredients of this medicine (listed in section 6),
  • if you are on renal dialysis,
  • if you have intestinal perforation or obstruction, severe inflammatory disease of the intestinal tract, such as Crohn's disease, ulcerative colitis, or toxic megacolon/megarectum.

Warnings and precautions

Consult your doctor before taking Resolor.

Be particularly careful with Resolor and inform your doctor:

  • if you have severe kidney disease,
  • if you have severe liver disease,
  • if you are currently under medical supervision due to a serious medical condition such as lung or heart disease, mental health or nervous system problems, cancer, AIDS, or a hormonal disorder.

If you have severe diarrhea, your contraceptive pill may not work properly, so it is recommended to use an additional contraceptive method. Read the instructions in the package leaflet of the contraceptive pill you are taking.

Using Resolor with other medicines

Tell your doctor if you are taking, have recently taken, or might take any other medicines.

Taking Resolor with food and drinks

Resolor can be taken with or without food and drinks at any time of day.

Pregnancy and breastfeeding

Resolor should not be used during pregnancy.

  • If you are pregnant or planning to become pregnant, consult your doctor.
  • Use an effective contraceptive method while taking Resolor to avoid pregnancy.
  • If you become pregnant during treatment with Resolor, consult your doctor.

During breastfeeding, prucalopride may pass into breast milk. Breastfeeding is not recommended during treatment with Resolor. Consult your doctor about this.

Consult your doctor or pharmacist before using any medicine.

Driving and using machines

It is unlikely that Resolor will affect your ability to drive or use machines. However, Resolor may occasionally cause dizziness and fatigue, especially on the first day of treatment, which may affect your ability to drive and use machines.

Resolor contains lactose

If your doctor has told you that you have an intolerance to some sugars, consult them before taking this medicine.

3. How to take Resolor

Follow exactly the administration instructions of this medicine contained in this package leaflet or as indicated by your doctor. In case of doubt, consult your doctor or pharmacist again. Take Resolor every day for the duration indicated by your doctor.

It is possible that your doctor may want to re-evaluate your condition and the benefit of continuing treatment after the first 4 weeks and at regular intervals thereafter.

The recommended dose of Resolor in most patients is one 2 mg tablet once a day.

If you are over 65 years of age or have severe liver disease, the initial dose is one 1 mg tablet once a day, which your doctor may increase to 2 mg per day if necessary.

Your doctor may also recommend a lower dose of one 1 mg tablet per day if you have severe kidney disease.

You will not get better results by taking higher doses than recommended.

Resolor should only be used in adults and should not be used in children or adolescents under 18 years of age.

If you take more Resolor than you should

It is important to take the dose prescribed by your doctor. If you have taken more Resolor than you should, you may experience diarrhea, headache, and/or nausea. In case of diarrhea, make sure to drink plenty of water.

If you forget to take Resolor

Do not take a double dose to make up for forgotten doses. Simply take the next dose at the usual time.

If you stop taking Resolor

If you stop taking Resolor, you may experience constipation again.

If you have any further questions about the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, Resolor can cause side effects, although not everybody gets them. Side effects mainly occur at the start of treatment and usually disappear after a few days of continued treatment.

The following side effects have been reported very commonly (may affect more than 1 in 10 people): headache, nausea, diarrhea, and abdominal pain.

The following side effects have been reported commonly (may affect up to 1 in 10 people): decreased appetite, dizziness, vomiting, indigestion (dyspepsia), flatulence, abnormal intestinal sounds, fatigue.

The following side effects have also been observed uncommonly (may affect up to 1 in 100 people): tremors, palpitations, rectal bleeding, increased frequency of urination (pollakiuria: increased frequency of urinating), fever, and general malaise. Consult your doctor if you experience palpitations.

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist, even if they are not listed in this package leaflet. You can also report side effects directly through the national reporting system listed in Appendix V. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Resolor

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the blister and carton after EXP. The expiry date is the last day of the month shown.

Store in the original blister to protect from moisture.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and further information

Composition of Resolor

The active substance is prucalopride.

One film-coated tablet of Resolor 1 mg contains 1 mg of prucalopride (as succinate).

One film-coated tablet of Resolor 2 mg contains 2 mg of prucalopride (as succinate).

The other ingredients are:

Lactose monohydrate (see section 2), microcrystalline cellulose, colloidal silicon dioxide, magnesium stearate, hypromellose, triacetin, titanium dioxide (E171), macrogol. The 2 mg tablet also contains red iron oxide (E172), yellow iron oxide (E172), and carmine aluminum lake (E132).

Appearance of the product and pack contents

Resolor 1 mg film-coated tablets are white to off-white, round tablets marked with “PRU 1” on one side.

Resolor 2 mg film-coated tablets are pink, round tablets marked with “PRU 2” on one side.

Resolor is available in unit dose aluminum/aluminum blisters (with calendar printed) containing 7 tablets. Each pack contains 7 x 1, 14 x 1, 28 x 1, or 84 x 1 film-coated tablets.

Not all pack sizes may be marketed.

Marketing authorization holder and manufacturer

Shire Pharmaceuticals Ireland Limited

Block 2 Miesian Plaza

50 – 58 Baggot Street Lower

Dublin 2

D02 HW68

Ireland

Manufacturer

Sanico NV

Veedijk 59

B-2300 Turnhout

Belgium

Date of last revision of this package leaflet: 11/2022.

Detailed information on this medicine is available on the European Medicines Agency website: http://www.ema.europa.eu.

Online doctors for RESOLOR 1 mg FILM-COATED TABLETS

Discuss questions about RESOLOR 1 mg FILM-COATED TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (32)
Doctor

Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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5.0 (4)
Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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5.0 (144)
Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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€50

Frequently Asked Questions

Is a prescription required for RESOLOR 1 mg FILM-COATED TABLETS?
RESOLOR 1 mg FILM-COATED TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in RESOLOR 1 mg FILM-COATED TABLETS?
The active ingredient in RESOLOR 1 mg FILM-COATED TABLETS is prucalopride. This information helps identify medicines with the same composition but different brand names.
Who manufactures RESOLOR 1 mg FILM-COATED TABLETS?
RESOLOR 1 mg FILM-COATED TABLETS is manufactured by Takeda Pharmaceuticals International Ag Ireland Branch. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of RESOLOR 1 mg FILM-COATED TABLETS online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether RESOLOR 1 mg FILM-COATED TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to RESOLOR 1 mg FILM-COATED TABLETS?
Other medicines with the same active substance (prucalopride) include RESOLOR 2 mg FILM-COATED TABLETS, Constella 290 micrograms hard capsules, GLYCILAX ADULT SUPPOSITORIES. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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