Bg pattern

PRODERMA 50 mg HARD CAPSULES

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use PRODERMA 50 mg HARD CAPSULES

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

Show original

Introduction

Package Leaflet: Information for the User

Proderma 50 mg Hard Capsules

Doxycycline

Read the entire package leaflet carefully before starting to take the medicine, as it contains important information for you.

  • Keep this package leaflet, as you may need to read it again.
  • If you have any doubts, consult your doctor or pharmacist.
  • This medicine has been prescribed to you only, and you should not give it to others, even if they have the same symptoms as you, as it may harm them.
  • If you experience side effects, consult your doctor or pharmacist, even if they are not listed in this package leaflet.

Contents of the Package Leaflet

  1. What Proderma 50 mg Hard Capsules are and what they are used for
  2. What you need to know before taking Proderma 50 mg Hard Capsules
  3. How to take Proderma 50 mg Hard Capsules
  4. Possible side effects
  5. Storage of Proderma 50 mg Hard Capsules
  6. Package Contents and Additional Information

1. What Proderma 50 mg Hard Capsules are and what they are used for

Doxycycline belongs to a group of medicines called tetracyclines, which are broad-spectrum antibiotics, active against multiple microorganisms.

Informative text about the use of antibiotics and precautions regarding their administration and disposal Doxycycline is primarily indicated for infections of the skin and soft tissues, respiratory tract infections, and genitourinary infections, such as:

  • Atypical pneumonia.
  • Psittacosis (disease transmitted to humans by certain birds, characterized by pneumonia, fever, and cough).
  • Typhus and other infections caused by microorganisms called rickettsias.
  • Sexually transmitted diseases.
  • Brucellosis (Malta fever).
  • Cholera.
  • Early stages of Lyme disease (disease transmitted by ticks).
  • Fever transmitted by lice and ticks.
  • Malaria.
  • Severe acne vulgaris.
Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before taking Proderma 50 mg Hard Capsules

Do not take Proderma 50 mg Hard Capsules

If you are allergic to doxycycline, tetracyclines, or any of the other components of Proderma 50 mg (listed in section 6).

Warnings and Precautions

Consult your doctor or pharmacist before starting to take Proderma 50 mg.

Children

Proderma 50 mg should not be administered during the dentition period (second half of pregnancy, lactation, and children under 8 years), as it may cause permanent tooth discoloration and delay bone development.

General

  • Bulging of the fontanelles (unossified space in the skull) has been reported in children, and intracranial hypertension (increased pressure of the cerebrospinal fluid in the brain) has been reported in both children and adults (see section 4. Possible side effects).
  • If you experience diarrhea while receiving treatment with doxycycline, consult your doctor.
  • If you take this medicine while lying down or without sufficient water, ulcers may appear in the digestive system; therefore, it is essential to follow the administration instructions (see section 3. How to take Proderma 50 mg Hard Capsules and section 4. Possible side effects).
  • If you have liver or kidney disease, consult your doctor.
  • In prolonged treatments, the doctor will perform renal and hepatic function tests.
  • If you have systemic lupus erythematosus, you should avoid using this medicine.
  • In case of direct sun exposure, skin redness may occur; if this happens, consult your doctor.
  • If you suffer from myasthenia gravis (a form of muscle weakness), consult your doctor before taking this medicine.
  • If you are going to have a urine test, inform the healthcare staff that you are being treated with this medicine, as doxycycline may interfere with the results.

Use of Proderma 50 mg Hard Capsules with other medicines

Inform your doctor or pharmacist if you are taking or have recently taken other medicines, including those purchased without a prescription.

Like all medicines, Proderma 50 mg can interact with some medicines, such as:

  • Antacids containing aluminum, calcium, and magnesium, as they decrease the absorption of Proderma 50 mg.
  • Antibiotics, as they may decrease the efficacy of Proderma 50 mg.
  • Methoxyflurane, as it may cause kidney toxicity when used with tetracyclines and Proderma 50 mg, which can be severe.
  • Anticoagulants (such as warfarin), as Proderma 50 mg may alter the effect of these anticoagulants; therefore, consult your doctor.
  • Medicines for the treatment of epilepsy, such as carbamazepine and phenytoin.
  • Oral contraceptives and barbiturates, as Proderma 50 mg may decrease their efficacy.
  • Chronic alcohol consumption may decrease the efficacy of Proderma 50 mg.

In case of doubt, consult your doctor or pharmacist.

Taking Proderma 50 mg Hard Capsules with food and drinks

  • During treatment with doxycycline, alcohol consumption should be avoided.
  • Proderma 50 mg should be administered with food or water to avoid esophageal irritation (see section 3. How to take Proderma 50 mg Hard Capsules and section 4. Possible side effects).

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

Breastfeeding

You should avoid taking this medicine during breastfeeding.

Driving and using machines

There is no evidence that Proderma 50 mg alters the ability to drive or use machines.

Proderma 50 mg Hard Capsules containsucrose.If your doctor has told you that you have an intolerance to certain sugars, consult with them before taking this medicine.

3. How to take Proderma 50 mg Hard Capsules

Follow the administration instructions for Proderma 50 mg exactly as indicated by your doctor. In case of doubt, consult your doctor or pharmacist again.

Remember to take your medicine.

Consult your doctor or pharmacist if you think the effect of doxycycline is not what you expected, either because it is too strong and causes unwanted side effects or because it is too weak and insufficient for the treatment of the infection.

IMPORTANT:

This medicine should be taken during a meal, accompanied by a large glass of water.

It is essential that, after taking the medicine, you wait at least one hour before lying down or going to bed to sleep.

The above recommendations aim to prevent the appearance of digestive problems, especially stomach ulcers.

Your doctor will indicate the duration of treatment with Proderma 50 mg. Do not stop treatment prematurely, even if you have started to improve.

Adults:the usual dose of doxycycline is 200 mg in one or two doses on the first day of treatment, followed by a maintenance dose of 100 mg/day. For the treatment of more severe infections, 200 mg/day should be administered throughout the treatment period. In general, treatment should continue until at least 24 to 48 hours after the disappearance of symptoms and fever.

Children over 8 years old:children over 8 years old who weigh 45 kg or less, the usual dose is 4 mg/kg of body weight on the first day of treatment, administered in a single dose or in two equal doses every 12 hours. In severe infections: 4 mg/kg of body weight every 24 hours, maintaining the same dose throughout treatment. Treatment should continue for 24 to 48 hours after the symptoms have disappeared.

If you take more Proderma 50 mg Hard Capsules than you should

If you have taken more Proderma 50 mg Hard Capsules than you should, consult your doctor or pharmacist immediately.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service. Phone: (91) 562 04 20, indicating the medicine and the amount ingested.

If you forget to take Proderma 50 mg Hard Capsules

If you forget to take a dose, take the next one when it is due. Do not take a double dose to make up for the forgotten dose.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, Proderma 50 mg can cause side effects, although not everyone gets them.

The following side effects have been detected after taking Proderma 50 mg:

Blood and lymphatic system disorders:blood disorders after tetracycline administration are very rare. However, cases of hemolytic anemia (consequence of excessive red blood cell destruction), thrombocytopenia (decrease in platelet count), neutropenia (decrease in neutrophil count), and eosinophilia (increase in eosinophil count) have been reported.

Nervous system disorders:infrequently, intracranial hypertension characterized by headache, nausea, vomiting, dizziness, tinnitus, and visual disturbances occurs. These symptoms resolve after withdrawal of the drug. Bulging of the fontanelles in children has also been reported.

Gastrointestinal disorders:digestive alterations such as esophageal ulcers (see section 3. How to take Proderma 50 mg Hard Capsules), nausea, stomach pain, diarrhea, loss of appetite, tongue inflammation, intestinal inflammation, and anogenital candidiasis (infection by a microscopic fungus) may occur.

Permanent tooth discoloration may also occur if doxycycline is used during dental development (second half of pregnancy, lactation, and children under 8 years).

Liver disorders:treatment with high doses may cause hepatitis and liver function disorders.

Skin and subcutaneous tissue disorders:urticaria, maculopapular rash (spots and small elevations of the skin), exudative erythema (redness and spots on the skin), multiform eruptions (redness and swelling of the skin), photosensitivity reactions, exceptionally exfoliative dermatitis (inflammation and peeling of the skin), and rarely Stevens-Johnson syndrome.

Frequency not known: photoonycholysis (nail pigmentation).

Musculoskeletal and connective tissue disorders:joint pain and muscle pain may occur, as well as delayed growth in children.

Kidney disorders:like all tetracyclines, doxycycline may cause elevated blood urea nitrogen levels.

General disorders:occasionally, severe hypersensitivity reactions (allergies) may occur, exceptionally including urticaria, angioedema (fluid retention in the vessels), hypotension (decreased blood pressure), pericarditis (inflammation of the tissue surrounding the heart), worsening of systemic lupus erythematosus, angioedema, serum sickness (allergic reaction to serum), and very rarely anaphylactic shock (unusual or exaggerated allergic reaction).

Jarisch-Herxheimer reaction: characterized by fever, chills, headache, muscle pain, and skin rash, which usually resolves spontaneously. It occurs shortly after starting treatment with doxycycline for spirochetal infections, such as Lyme disease.

If you think any of the side effects you are experiencing is serious or if you notice any side effect not mentioned in this package leaflet, inform your doctor or pharmacist.

Reporting side effects

If you experience any side effects, consult your doctor or pharmacist, even if they are not listed in this package leaflet. You can also report them directly through the Spanish Medicines and Health Products Agency's website: www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Proderma 50 mg Hard Capsules

Keep out of sight and reach of children.

No special storage conditions are required.

Do not use this medicine after the expiration date stated on the carton after EXP. The expiration date is the last day of the month indicated.

Medicines should not be disposed of via wastewater or household waste. Place the packaging and any unused medicines in the pharmacy's SIGRE collection point. If in doubt, ask your pharmacist how to dispose of the packaging and any unused medicines. This will help protect the environment.

6. Package Contents and Additional Information

Composition of Proderma 50 mg Hard Capsules

  • The active ingredient is doxycycline. Each capsule contains 50 mg of doxycycline (as hyclate).
  • The other ingredients (excipients) are: sucrose, cornstarch, crospovidone, polyaminomethacrylate (Eudragit E100), talc, gelatin, carmine indigo (E132), quinoline yellow (E104), and titanium dioxide (E171).

Appearance of the product and package contents

Proderma 50 mg is available in packs of 30 capsules.

Other presentations:

Proderma 100 mg Hard Capsules

Proderma 200 mg Hard Capsules

Marketing Authorization Holder

INDUSTRIAL FARMACÉUTICA CANTABRIA, S.A.

Carretera de Cazoña-Adarzo, s/n.

39011, Santander

Spain

Manufacturer

INDUSTRIAL FARMACÉUTICA CANTABRIA, S.A.

C/ Pirita, 9 28850 Torrejón de Ardoz (Madrid)

Spain

or

TOLL MANUFACTURING SERVICES, S.L.

Aragoneses, 2

28108 Alcobendas (Madrid)

Spain

This package leaflet was approved in June 2022.

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for PRODERMA 50 mg HARD CAPSULES

Discuss questions about PRODERMA 50 mg HARD CAPSULES, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (25)
Doctor

Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
  • Structured support for undiagnosed complaints.
  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Camera Book a video appointment
€70
0.0 (0)
Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
Camera Book a video appointment
€58
0.0 (6)
Doctor

Daniel Cichi

Family medicine 24 years exp.

Dr Daniel Cichi is a family medicine doctor with over 20 years of clinical experience. He provides online consultations for adults, supporting patients with acute symptoms, chronic conditions, and everyday health concerns that require timely medical guidance. His background includes work in emergency care, ambulance services, and family medicine, which allows him to assess symptoms quickly, identify warning signs, and help patients choose the safest next steps – whether that means home care, treatment adjustment, or in-person evaluation. Patients commonly consult Dr Daniel Cichi for: 

  • acute symptoms: fever, infections, flu-like illness, cough, sore throat, shortness of breath;
  • chest discomfort, palpitations, dizziness, fatigue, and blood pressure concerns;
  • digestive problems: abdominal pain, nausea, diarrhoea, constipation, reflux;
  • sexually transmitted infections, erectile dysfunction;
  • muscle, joint, and back pain, minor injuries, post-traumatic symptoms;
  • chronic conditions: hypertension, diabetes, high cholesterol, thyroid disorders, weight loss, hair loss;
  • review and interpretation of lab tests, imaging reports, and medical documents;
  • medication review and treatment adjustment;
  • medical advice while travelling or living abroad;
  • second opinions and guidance on whether in-person care is needed.

Dr Cichi’s consultations are structured and practical. He focuses on clear explanations, risk assessment, and actionable recommendations, helping patients understand their symptoms and make informed decisions about their health.

Camera Book a video appointment
€55
5.0 (32)
Doctor

Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

Camera Book a video appointment
€60

Frequently Asked Questions

Is a prescription required for PRODERMA 50 mg HARD CAPSULES?
PRODERMA 50 mg HARD CAPSULES requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in PRODERMA 50 mg HARD CAPSULES?
The active ingredient in PRODERMA 50 mg HARD CAPSULES is doxycycline. This information helps identify medicines with the same composition but different brand names.
How much does PRODERMA 50 mg HARD CAPSULES cost in pharmacies?
The average pharmacy price for PRODERMA 50 mg HARD CAPSULES is around 2.58 EUR. Prices may vary depending on the manufacturer and dosage form.
Who manufactures PRODERMA 50 mg HARD CAPSULES?
PRODERMA 50 mg HARD CAPSULES is manufactured by Industrial Farmaceutica Cantabria S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of PRODERMA 50 mg HARD CAPSULES online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether PRODERMA 50 mg HARD CAPSULES is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to PRODERMA 50 mg HARD CAPSULES?
Other medicines with the same active substance (doxycycline) include DOSIL 100 mg HARD CAPSULES, DOXICICLINA NORMON 100 mg FILM-COATED TABLETS, DOXICLAT 100 mg FILM-COATED TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
bg-pattern-dark

Stay informed about Oladoctor

News about new services, product updates and useful information for patients.

Follow us on social media