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PLERIXAFOR TILLOMED 20 mg/ml INJECTABLE SOLUTION

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use PLERIXAFOR TILLOMED 20 mg/ml INJECTABLE SOLUTION

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introducción

Prospecto: información para el usuario

Plerixafor Tillomed 20 mg/ml solución inyectable EFG

Lea todo el prospecto detenidamente antes de empezar a usar este medicamento, porque contiene información importante para usted.

  • Conserve este prospecto, ya que puede tener que volver a leerlo.
  • Si tiene alguna duda, consulte a su médico.
  • Si experimenta efectos adversos, consulte a su médico o enfermero, incluso si se trata de efectos adversos que no aparecen en este prospecto. Ver sección 4.

Contenido del prospecto

  1. Qué es Plerixafor Tillomed y para qué se utiliza
  2. Qué necesita saber antes de empezar a usar Plerixafor Tillomed
  3. Cómo usar Plerixafor Tillomed
  4. Posibles efectos adversos
  5. Conservación de Plerixafor Tillomed
  6. Contenido del envase e información adicional

1. Qué es Plerixafor Tillomed y para qué se utiliza

Plerixafor Tillomed contiene el principio activo plerixafor que bloquea una proteína de la superficie de células madre hematopoyéticas. Esta proteína “fija" las células madre de la sangre a la médula ósea. Plerixafor mejora la liberación de las células madre al torrente circulatorio (movilización). Las células madre se pueden recoger con un aparato que separa los componentes de la sangre (máquina de aféresis), posteriormente congelarlas y almacenarlas hasta su trasplante.

Si la movilización es escasa, se administra plerixafor para ayudar a recoger células madre de la sangre del paciente para la recogida, almacenamiento y reintroducción (trasplante),

  • En pacientes adultos con linfoma (un cáncer de glóbulos blancos) o mieloma múltiple (un cáncer que afecta a las células plasmáticas de médula ósea).
  • En niños de 1 a menos de 18 años con linfoma o tumores sólidos.
Doctor consultation

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Discuss your symptoms and treatment with a doctor online.

2. Qué necesita saber antes de empezar a usar Plerixafor Tillomed

No usePlerixafor Tillomed:

  • si es alérgico a plerixafor o a alguno de los demás componentes de este medicamento (incluidos en la sección 6).

Advertencias y precauciones

Consulte a su médico antes de empezar a usar plerixafor.

Informe a su médico:

  • si tiene o ha tenido cualquier problema de corazón;
  • si tiene problemas de riñón. Su médico puede ajustarle la dosis;
  • si tiene un número alto de glóbulos blancos;
  • si tiene un número bajo de plaquetas;
  • si tiene antecedentes de sensación de desmayo o de mareo estando de pie o sentado o se ha desmayado anteriormente tras las inyecciones.

Su médico puede realizarle análisis de sangre periódicamentepara controlar el número de células de la sangre.

No se recomienda el uso de plerixafor para la movilización de células madre si tiene leucemia (un cáncer de la sangre o de médula ósea).

Uso dePlerixafor Tillomedcon otros medicamentos

Informe a su médico o farmacéutico si está tomando, ha tomado recientemente o podría tener que tomar cualquier otro medicamento.

Embarazo y lactancia

No debe utilizar plerixafor si está embarazada, puesto que no se dispone de datos de los efectos de plerixafor en mujeres embarazadas. Es importante que informe a su médico si está embarazada, cree que podría estarlo o tiene intención de quedarse embarazada. Se recomienda el uso de métodos anticonceptivos si está en edad fértil.

No debe dar el pecho si está usando plerixafor ya que se desconoce si plerixafor pasa a la leche materna.

Conducción y uso de máquinas

Plerixafor puede causar mareos y fatiga. Por tanto, debe evitar conducir si se siente mareado, cansado o no se siente bien.

Plerixafor Tillomedcontienesodio

  • Este medicamento contiene menos de 1 mmol de sodio (23 mg) por dosis, esto es, esencialmente «exento de sodio».

3. Cómo usar Plerixafor Tillomed

Su médico o un enfermero le inyectará su medicamento.

Primero recibirá G-CSF y luego le administraránPlerixafor Tillomed

La movilización comenzará administrándole primero otro medicamento llamado G-CSF (factor estimulante de colonias de granulocitos). El G-CSF ayudará a plerixafor a funcionar apropiadamente en su organismo. Si desea más información acerca de G-CSF, pregunte a su médico y lea el correspondiente prospecto.

¿CuántoPlerixafor Tillomedse administra?

La dosis recomendada en adultos es de 20 mg (dosis fija) o 0,24 mg/kg de peso/día.

La dosis recomendada en niños, de 1 a menos de 18 años, es de 0,24 mg/kg de peso corporal/día.

Su dosis dependerá de su peso corporal, que debe medirse la semana anterior a que reciba la primera dosis. Si tiene problemas de riñón moderados o graves, su médico reducirá la dosis.

¿Cómo se administraPlerixafor Tillomed?

Plerixafor Tillomed se administra mediante inyección subcutánea (bajo la piel).

¿Cuándo se administraPlerixafor Tillomedpor primera vez?

Recibirá la primera dosis entre 6 y 11 horas antes de la aféresis (recogida de las células madre de su sangre).

¿Cuánto durará la administración dePlerixafor Tillomed?

El tratamiento dura de 2 a 4 días consecutivos (en algunos casos hasta 7 días), hasta que se hayan recogido suficientes células madre para su trasplante. En algunos casos, no es posible recoger suficiente número de células madre, por lo que se interrumpirá el intento de recogida.

Medicine questions

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4. Posibles efectos adversos

Al igual que todos los medicamentos, este medicamento puede producir efectos adversos, aunque no todas las personas los sufran.

Informe a su médico inmediatamente si

  • nada más recibir plerixafor presenta erupción cutánea, hinchazón alrededor de los ojos, dificultad para respirar o falta de oxígeno, sensación de mareo estando de pie o sentado, sensación de desmayo o se desmaya;
  • siente dolor en la parte superior izquierda del abdomen (vientre) o en su hombro izquierdo.

Efectos adversos muy frecuentes(pueden afectar a más de 1 de cada 10 personas):

  • diarrea;
  • náuseas;
  • enrojecimiento o irritación en el lugar de inyección;
  • recuento bajo de glóbulos rojos en las pruebas de laboratorio (anemia en niños).

Efectos adversos frecuentes(pueden afectar hasta 1 de cada 10 personas):

  • dolor de cabeza;
  • mareos, sensación de cansancio o de malestar;
  • dificultad para dormir;
  • flatulencia, estreñimiento, indigestión, vómitos;
  • síntomas estomacales como dolor, hinchazón o molestias;
  • sequedad de boca, entumecimiento alrededor de la boca;
  • sudoración;
  • enrojecimiento generalizado de la piel;
  • dolor en las articulaciones;
  • dolor muscular y de huesos.

Efectos adversos poco frecuentes(pueden afectar hasta 1 de cada 100 personas):

  • reacciones alérgicas como erupción cutánea, hinchazón alrededor de los ojos, dificultad para respirar;
  • reacciones anafilácticas, incluyendo shock anafiláctico;
  • sueños alterados, pesadillas.

En raras ocasiones, los efectos adversos gastrointestinales pueden ser graves (diarrea, vómitos, dolor de estómago y náuseas).

Infarto de miocardio

En los ensayos clínicos, con poca frecuencia, los pacientes con factores de riesgo para padecer un infarto de miocardio padecieron un infarto de miocardio después de la administración de plerixafor y G-CSF. Informe a su médico inmediatamente si tiene molestias en el pecho.

Hormigueo y entumecimiento

El hormigueo y entumecimiento son frecuentes en pacientes que están recibiendo tratamiento para el cáncer. Aproximadamente uno de cada cinco pacientes los sufren. Sin embargo, estos efectos no parecen ocurrir con más frecuencia cuando se utiliza plerixafor.

Puede tener también un aumento del número de las células blancas de la sangre (leucocitosis), en sus análisis de sangre.

Comunicaciónde efectos adversos

Si experimenta cualquier tipo de efecto adverso, consulte a su médico o farmacéutico, incluso si se trata de posibles efectos adversos que no aparecen en este prospecto. También puede comunicarlos directamente a través del Sistema Español de Farmacovigilancia de Medicamentos de Uso Humano: https://www.notificaram.es. Mediante la comunicación de efectos adversos usted puede contribuir a proporcionar más información sobre la seguridad de este medicamento.

5. Conservación de Plerixafor Tillomed

Mantener este medicamento fuera de la vista y del alcance de los niños.

No utilice este medicamento después de la fecha de caducidad que aparece en el envase y en el vial después de CAD. La fecha de caducidad es el último día del mes que se indica.

Conservar por debajo de 25 °C. Una vez abierto el vial, Plerixafor Tillomed debe utilizarse inmediatamente.

Los medicamentos no se deben tirar por los desagües ni a la basura. Pregunte a su farmacéutico cómo deshacerse de los envases y de los medicamentos que ya no necesita. De esta forma, ayudará a proteger el medio ambiente.

6. Contenido del envase e información adicional

Composición de Plerixafor Tillomed

  • El principio activo es plerixafor. Cada ml de solución inyectable contiene 20 mg de plerixafor. Cada vial contiene 24 mg de plerixafor en 1,2 ml de solución.
  • Los demás componentes (excipientes) son cloruro de sodio, ácido clorhídrico e hidróxido de sodio para ajustar el pH, agua para preparaciones inyectables y nitrógeno.

Aspecto del producto y contenido del envase

Plerixafor Tillomed se presenta como una solución inyectable transparente incolora o amarilla pálida contenida en un vial de vidrio con un tapón de goma. Cada vial contiene 1,2 ml de solución.

Cada envase contiene 1 vial.

Titular de la autorización de comercialización y responsable de la fabricación

Titular de la autorización de comercialización

Laboratorios Tillomed Spain, S.L.U.

C/ Cardenal Marcelo Spínola 8, planta 1ª-puerta F 28016 Madrid

España

Responsable de la fabricación(1)

MIAS Pharma Limited

Suite 1, First floor,

Stafford House, Strand Road,

Portmarnock,

Co. Dublin, D13 WC83

Irlanda

Tillomed Malta Limited

Malta Life Sciences Park

LS2.01.06 Industrial Estate

San Gwann SGN 3000 Malta

1 sólo se indica en el prospecto el fabricante del producto

Este medicamento está autorizado en los estados miembros del Espacio Económico Europeo con los siguientes nombres:

Nombre del país

Nombre del producto

Alemania

Plerixafor Tillomed 20 mg/ml Injektionslösung

Italia

Plerixafor Tillomed

Francia

Plerixafor Tillomed 20 mg/ml, solution injectable

España

Plerixafor Tillomed 20 mg/ml solución inyectable EFG

Fecha de la última revisión de este prospecto:marzo 2023

Otras fuentes de información

La información detallada de este medicamento está disponible en la página web de la Agencia Española de Medicamentos y Productos Sanitarios (AEMPS): http://www.aemps.gob.es/

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Family medicine 18 years exp.

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Tarek Agami

General medicine 11 years exp.

Dr. Tarek Agami is a general practitioner registered in both Portugal and Israel, with broad experience in family and preventive medicine. He offers online consultations for adults and children, providing personalised support for primary care needs, chronic disease management, and everyday health concerns.

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Dr. Agami provides medical support for patients using GLP-1 medications (such as Ozempic or Mounjaro) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Portugal and Israel.

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Hocine Lokchiri

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Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

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Chikeluo Okeke

General medicine 4 years exp.

Dr Chikeluo Okeke is an internal medicine doctor with extensive international clinical experience. Originally from Nigeria, he has worked across multiple European healthcare systems and currently practises in Sweden. This professional path has given him a strong understanding of different medical approaches and the ability to work effectively with patients from diverse cultural and linguistic backgrounds.

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Anastasiia Shalko

Family medicine 13 years exp.

Dr. Anastasiia Shalko is a general practitioner with a background in both paediatrics and general medicine. She graduated from Bogomolets National Medical University in Kyiv and completed her paediatric internship at the P.L. Shupyk National Medical Academy of Postgraduate Education. After working as a paediatrician in Kyiv, she relocated to Spain, where she has been practising general medicine since 2015, providing care for both adults and children.Her work focuses on urgent, short-term medical concerns – situations where patients need quick guidance, symptom assessment and clear next steps. She helps people understand whether their symptoms require in-person evaluation, home management or a change in treatment. Common reasons for booking an online consultation include:

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Dr. Shalko works specifically with urgent and short-term problems, providing practical recommendations and helping patients determine the safest next step. She explains symptoms clearly, guides patients through decision-making and offers straightforward medical advice for everyday acute issues.She does not provide long-term management of chronic conditions, ongoing follow-up or comprehensive care plans for complex long-term illnesses. Her consultations are designed for acute symptoms, sudden concerns and situations where timely medical input is important.With clinical experience in both paediatrics and general medicine, Dr. Shalko confidently supports adults and children. Her communication style is clear, simple and reassuring, helping patients feel informed and supported throughout the consultation.

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Daniel Cichi

Family medicine 24 years exp.

Dr Daniel Cichi is a family medicine doctor with over 20 years of clinical experience. He provides online consultations for adults, supporting patients with acute symptoms, chronic conditions, and everyday health concerns that require timely medical guidance. His background includes work in emergency care, ambulance services, and family medicine, which allows him to assess symptoms quickly, identify warning signs, and help patients choose the safest next steps – whether that means home care, treatment adjustment, or in-person evaluation. Patients commonly consult Dr Daniel Cichi for: 

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Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

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Frequently Asked Questions

Is a prescription required for PLERIXAFOR TILLOMED 20 mg/ml INJECTABLE SOLUTION?
PLERIXAFOR TILLOMED 20 mg/ml INJECTABLE SOLUTION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in PLERIXAFOR TILLOMED 20 mg/ml INJECTABLE SOLUTION?
The active ingredient in PLERIXAFOR TILLOMED 20 mg/ml INJECTABLE SOLUTION is plerixafor. This information helps identify medicines with the same composition but different brand names.
Who manufactures PLERIXAFOR TILLOMED 20 mg/ml INJECTABLE SOLUTION?
PLERIXAFOR TILLOMED 20 mg/ml INJECTABLE SOLUTION is manufactured by Laboratorios Tillomed Spain S.L.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of PLERIXAFOR TILLOMED 20 mg/ml INJECTABLE SOLUTION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether PLERIXAFOR TILLOMED 20 mg/ml INJECTABLE SOLUTION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to PLERIXAFOR TILLOMED 20 mg/ml INJECTABLE SOLUTION?
Other medicines with the same active substance (plerixafor) include MOZOBIL 20 mg/ml INJECTABLE SOLUTION, PLERIXAFOR ACCORD 20 mg/ml INJECTABLE SOLUTION, PLERIXAFOR EUGIA 20 mg/ml INJECTABLE SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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