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MOZOBIL 20 mg/ml INJECTABLE SOLUTION

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About the medicine

How to use MOZOBIL 20 mg/ml INJECTABLE SOLUTION

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Mozobil 20mg/ml solution for injection

plerixafor

Read all of this leaflet carefully before you start usingthismedicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor.
  • If you experience any side effects, talk to your doctor or pharmacist, even if they are not listed in this leaflet. See section 4.

Contents of the pack

  1. What is Mozobil and what is it used for
  2. What you need to know before you use Mozobil
  3. How to use Mozobil
  4. Possible side effects
    1. Storage of Mozobil
  1. Contents of the pack and other information

1. What is Mozobil and what is it used for

Mozobil contains the active substance plerixafor, which blocks a protein on the surface of hematopoietic stem cells. This protein "fixes" the stem cells to the bone marrow. Plerixafor improves the release of stem cells into the bloodstream (mobilization). The stem cells can then be collected using a machine that separates the components of the blood (apheresis machine), frozen, and stored until transplantation.

If mobilization is poor, Mozobil is given to help collect stem cells from the patient's blood for collection, storage, and re-infusion (transplantation),

  • In adult patients with lymphoma (a type of blood cancer) or multiple myeloma (a type of cancer that affects the plasma cells in the bone marrow).
  • In children from 1 to less than 18 years with lymphoma or solid tumors.
Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you use Mozobil

Do not use Mozobil

  • if you are allergic to plerixafor or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions

Talk to your doctor before you start using Mozobil.

Tell your doctor:

  • if you have or have had any heart problems.
  • if you have kidney problems. Your doctor may adjust your dose.
  • if you have a high white blood cell count.
  • if you have a low platelet count.
  • if you have a history of feeling faint or dizzy while standing or sitting, or if you have fainted after injections in the past.

Your doctor may perform blood tests periodicallyto monitor your blood cell count.

Mozobil is not recommended for stem cell mobilization if you have leukemia (a type of blood or bone marrow cancer).

Using Mozobil with other medicines

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.

Pregnancy and breastfeeding

Do not use Mozobil if you are pregnant, as there is no data on the effects of Mozobil in pregnant women. It is important that you inform your doctor if you are pregnant, think you may be pregnant, or plan to become pregnant. The use of contraceptive methods is recommended if you are of childbearing age.

Do not breastfeed if you are using Mozobil, as it is not known whether Mozobil passes into breast milk.

Driving and using machines

Mozobil may cause dizziness and fatigue. Therefore, you should avoid driving if you feel dizzy, tired, or unwell.

Mozobil contains sodium

This medicine contains less than 1 mmol of sodium (23 mg) per dose, which is considered essentially "sodium-free".

3. How to use Mozobil

Your doctor or nurse will inject the medicine into you.

First, you will receive G-CSF and then Mozobil will be administered

Mobilization will begin by administering another medicine called G-CSF (granulocyte-colony stimulating factor) first. G-CSF will help Mozobil work properly in your body. If you want more information about G-CSF, ask your doctor and read the corresponding package leaflet.

How much Mozobil is administered?

The recommended dose in adults is 20 mg (fixed dose) or 0.24 mg/kg body weight/day.

The recommended dose in children from 1 to less than 18 years is 0.24 mg/kg body weight/day.

Your dose will depend on your body weight, which must be measured the week before you receive the first dose. If you have moderate or severe kidney problems, your doctor will reduce the dose.

How is Mozobil administered?

Mozobil is administered by subcutaneous injection (under the skin).

When is Mozobil administered for the first time?

You will receive the first dose between 6 and 11 hours before apheresis (collection of stem cells from your blood).

How long will Mozobil administration last?

Treatment lasts from 2 to 4 consecutive days (in some cases up to 7 days), until enough stem cells have been collected for transplantation. In some cases, it may not be possible to collect enough stem cells, so the collection attempt will be interrupted.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Tell your doctor immediately if

  • soon after receiving Mozobil, you experience a rash, swelling around the eyes, difficulty breathing, or a lack of oxygen, dizziness while standing or sitting, feeling faint, or fainting
  • you feel pain in the upper left part of your abdomen (stomach) or in your left shoulder

Very common side effects(may affect more than 1 in 10 people)

  • diarrhea, nausea, redness or irritation at the injection site
  • low red blood cell count in laboratory tests (anemia in children)

Common side effects(may affect up to 1 in 10 people)

  • headache
  • dizziness, feeling tired or unwell
  • difficulty sleeping
  • flatulence, constipation, indigestion, vomiting
  • stomach symptoms such as pain, bloating, or discomfort
  • dry mouth, numbness around the mouth
  • sweating, flushing, joint pain, muscle and bone pain

Uncommon side effects(may affect up to 1 in 100 people)

  • allergic reactions such as rash, swelling around the eyes, difficulty breathing
  • anaphylactic reactions, including anaphylactic shock
  • disturbed dreams, nightmares

In rare cases, gastrointestinal side effects can be severe (diarrhea, vomiting, stomach pain, and nausea).

Myocardial infarction

In clinical trials, patients with risk factors for myocardial infarction rarely experienced a myocardial infarction after administration of Mozobil and G-CSF. Tell your doctor immediately if you experience chest discomfort.

Numbness and tingling

Numbness and tingling are common in patients receiving cancer treatment. About one in five patients experience them. However, these effects do not seem to occur more frequently when Mozobil is used.

You may also have an increased white blood cell count in your blood tests.

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist, even if they are not listed in this leaflet. You can also report side effects directly via the national reporting system listed in Appendix V. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Mozobil

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton and vial.

This medicine does not require any special storage conditions.

Once the vial is opened, Mozobil must be used immediately.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and other information

What Mozobil contains

  • The active substance is plerixafor. Each ml of solution for injection contains 20 mg of plerixafor. Each vial contains 24 mg of plerixafor in 1.2 ml of solution.
  • The other ingredients are sodium chloride, hydrochloric acid (concentrated), sodium hydroxide for pH adjustment, and water for injections.

Appearance and packaging

Mozobil is a clear, colorless or pale yellow solution for injection in a glass vial with a latex-free rubber stopper. Each vial contains 1.2 ml of solution.

Each pack contains 1 vial.

Marketing Authorisation Holder

Sanofi B.V., Paasheuvelweg 25, 1105 BP Amsterdam, Netherlands.

Manufacturer

Genzyme Ireland Ltd., IDA Industrial Park, Old Kilmeaden Road, Waterford, Ireland.

You can request more information about this medicine from the local representative of the Marketing Authorisation Holder:

Belgium/Belgique/Belgien/Luxembourg/Luxemburg

Sanofi Belgium

Tel: +32 2 710 54 00

Lithuania

Swixx Biopharma UAB

Tel: +370 5 236 91 40

Bulgaria

SANOFI BULGARIA EOOD

Tel: +359 (0)2 4942 480

Hungary

SANOFI-AVENTIS Zrt.

Tel: +36 1 505 0050

Czech Republic

Sanofi s.r.o.

Tel: +420 233 086 111

Malta

Sanofi S.r.l.

Tel: +39 02 39394275

Denmark

Sanofi A/S

Tel: +45 45 16 70 00

Netherlands

Sanofi B.V.

Tel: +31 20 245 4000

Germany

Sanofi-Aventis Deutschland GmbH

Tel: 0800 52 52 010

Tel from abroad: +49 69 305 21 131

Norway

sanofi-aventis Norge AS

Tel: +47 67 10 71 00

Estonia

Swixx Biopharma OÜ

Tel: +372 640 10 30

Austria

sanofi-aventis GmbH

Tel: +43 1 80 185 - 0

Greece

Sanofi-Aventis Μονοπρ?σωπη AEBE

Tel: +30 210 900 1600

Poland

sanofi-aventis Sp. z o.o.

Tel: +48 22 280 00 00

Spain

sanofi-aventis, S.A.

Tel: +34 93 485 94 00

Portugal

Sanofi – Produtos Farmacêuticos, Lda.

Tel: +351 21 35 89 400

France

Sanofi Winthrop Industrie

Tel: 0 800 222 555

Call from abroad: +33 1 57 63 23 23

Romania

Sanofi Romania SRL

Tel: +40 (0)21 317 31 36

Croatia

Swixx Biopharma d.o.o.

Tel: +385 1 2078 500

Slovenia

Swixx Biopharma d.o.o.

Tel: +386 1 235 51 00

Ireland

sanofi-aventis Ireland Ltd T/A SANOFI

Tel: +353 (0)1 4035 600

Slovakia

Swixx Biopharma s.r.o.

Tel: +421 2 208 33 600

Iceland

Vistor hf.

Tel: +354 535 7000

Finland

Sanofi Oy

Tel: +358 201 200 300

Italy

Sanofi S.r.l.

Tel: 800536389

Sweden

Sanofi AB

Tel: +46 (0)8 634 50 00

Latvia

Swixx Biopharma SIA

Tel: +371 6 616 47 50

Cyprus

C.A. Papaellinas Ltd.

Tel: +357 22 741741

United Kingdom (Northern Ireland)

sanofi-aventis Ireland Ltd. T/A SANOFI

Tel: +44 (0)800 035 2525

Date of last revision of thisleaflet:

Other sources of information

Detailed information on this medicine is available on the European Medicines Agency website: http://www.ema.europa.eu/.

Online doctors for MOZOBIL 20 mg/ml INJECTABLE SOLUTION

Discuss questions about MOZOBIL 20 mg/ml INJECTABLE SOLUTION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Daniel Cichi

Family medicine 24 years exp.

Dr Daniel Cichi is a family medicine doctor with over 20 years of clinical experience. He provides online consultations for adults, supporting patients with acute symptoms, chronic conditions, and everyday health concerns that require timely medical guidance.

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Dr Cichi’s consultations are structured and practical. He focuses on clear explanations, risk assessment, and actionable recommendations, helping patients understand their symptoms and make informed decisions about their health.
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Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

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Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

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Dr. Lokchiri’s professional training includes:

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He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

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Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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Doctor

Alina Tsurkan

Family medicine 13 years exp.

Dr. Alina Tsurkan is a licensed family medicine physician based in Portugal, offering online consultations for adults and children. She provides professional primary care, with a focus on prevention, accurate diagnosis, and long-term management of acute and chronic conditions.

Dr. Tsurkan supports patients with a wide range of health issues, including:

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Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

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Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
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Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Frequently Asked Questions

Is a prescription required for MOZOBIL 20 mg/ml INJECTABLE SOLUTION?
MOZOBIL 20 mg/ml INJECTABLE SOLUTION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in MOZOBIL 20 mg/ml INJECTABLE SOLUTION?
The active ingredient in MOZOBIL 20 mg/ml INJECTABLE SOLUTION is plerixafor. This information helps identify medicines with the same composition but different brand names.
Who manufactures MOZOBIL 20 mg/ml INJECTABLE SOLUTION?
MOZOBIL 20 mg/ml INJECTABLE SOLUTION is manufactured by Sanofi B.V.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of MOZOBIL 20 mg/ml INJECTABLE SOLUTION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether MOZOBIL 20 mg/ml INJECTABLE SOLUTION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to MOZOBIL 20 mg/ml INJECTABLE SOLUTION?
Other medicines with the same active substance (plerixafor) include PLERIXAFOR ACCORD 20 mg/ml INJECTABLE SOLUTION, PLERIXAFOR EUGIA 20 mg/ml INJECTABLE SOLUTION, PLERIXAFOR GLENMARK 20 mg/ml INJECTABLE SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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