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MOTILIUM 1 mg/ml ORAL SUSPENSION

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About the medicine

How to use MOTILIUM 1 mg/ml ORAL SUSPENSION

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Motilium 1 mg/ml Oral Suspension

Domperidone

Read all of this leaflet carefully before you start taking this medicine.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you, do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the Package Leaflet

  1. What is Motilium and what is it used for
  2. What you need to know before you take Motilium
  3. How to take Motilium
  4. Possible side effects
  5. Storing Motilium
  6. Contents of the pack and other information

1. What is Motilium and what is it used for

This medicine is used in adults and adolescents (12 years of age and older and weighing 35 kg or more) to treat nausea (feeling sick) and vomiting.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you take Motilium

Do not take Motilium

  • If you are allergic (hypersensitive) to domperidone or any of the other ingredients of Motilium.
  • If you have stomach bleeding or severe abdominal pain or persistent black stools.
  • If you have a blockage or perforation of the intestine.
  • If you have a tumor of the pituitary gland (prolactinoma).
  • If you have moderate or severe liver disease.
  • If your ECG (electrocardiogram) shows a heart problem called "prolonged QT corrected interval".
  • If you have or have had a problem where your heart does not pump blood to the whole body as it should (this is called heart failure).
  • If you have a problem where you have low levels of potassium or magnesium in the blood or high levels of potassium in the blood.
  • If you are taking certain medicines (see "Using other medicines").

Warnings and Precautions

Before taking this medicine, talk to your doctor if you:

  • have liver problems (liver dysfunction or liver failure) (see "Do not take Motilium")
  • have kidney problems (kidney dysfunction or kidney failure). In this case, it is recommended to ask your doctor for advice in case of prolonged treatment, as you may need a lower dose or take this medicine less frequently. Your doctor may want to examine you regularly.

Domperidone may be associated with an increased risk of heart rhythm disorders and cardiac arrest. This risk is more likely in patients over 60 years of age or in those taking doses higher than 30 mg/day. The risk also increases when domperidone is given with certain other medicines. Tell your doctor or pharmacist if you are taking medicines to treat infections (caused by fungi or bacteria) and/or if you have heart problems or HIV/AIDS (see the section "Using other medicines").

Domperidone should be used at the lowest effective dose.

While taking domperidone, contact your doctor if you experience heart rhythm disorders, such as palpitations, difficulty breathing, or loss of consciousness. In this case, treatment with domperidone should be discontinued.

Adolescents who weigh less than 35 kg and children

Motilium should not be given to adolescents 12 years of age and older who weigh less than 35 kg, or to children under 12 years of age, as it is not effective in these age groups.

Using other medicines

Do not take Motilium if you are taking medicines to treat:

  • fungal infections, e.g. pentamidine or azole antifungals, specifically itraconazole, ketoconazole by mouth, fluconazole, posaconazole, or voriconazole
  • bacterial infections, specifically erythromycin, clarithromycin, telithromycin, levofloxacin, moxifloxacin, spiramycin (these are antibiotics)
  • heart problems or high blood pressure (e.g. amiodarone, dronedarone, ibutilide, disopyramide, dofetilide, sotalol, hydroquinidine, quinidine)
  • psychosis (e.g. haloperidol, pimozide, sertindole)
  • depression (e.g. citalopram, escitalopram)
  • gastrointestinal disorders (e.g. cisapride, dolasetron, prucalopride)
  • allergies (e.g. mequitazine, mizolastine)
  • malaria (in particular halofantrine, lumefantrine)
  • HIV/AIDS (e.g. ritonavir or saquinavir, these are protease inhibitors)
  • Hepatitis C (e.g. telaprevir)
  • cancer (e.g. toremifene, vandetanib, vincamine)

Do not take Motilium if you are taking certain other medicines (e.g. bepridil, difemanil, methadone).

Tell your doctor or pharmacist if you are using medicines to treat infections, heart problems, or HIV/AIDS.

Motilium and Apomorphine

Before using Motilium and apomorphine, your doctor will make sure that you can take both medicines at the same time. Consult your doctor or specialist for personalized advice. For more information, see the apomorphine package leaflet.

It is important to ask your doctor or pharmacist if Motilium is safe for you when using any other medicine, even those bought without a prescription.

Taking Motilium with food and drinks

Take Motilium before meals, as its absorption may be slightly delayed if taken after meals.

Pregnancy

It is not known if Motilium is safe in pregnant women. If you are pregnant or think you may be pregnant, tell your doctor, who will decide if you can take Motilium.

Breast-feeding

Small amounts of domperidone have been detected in breast milk. Domperidone may cause unwanted effects that affect the heart of the breastfed baby. Domperidone should be used during breastfeeding only if your doctor considers it clearly necessary. Consult your doctor for advice before taking this medicine.

Driving and using machines

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

Some patients have reported feeling dizzy or drowsy after taking Motilium. Do not drive or use machinery while taking Motilium until you know how it affects you.

Important information about some of the ingredients of Motilium

  • Motilium suspension contains less than 23 milligrams (1 millimole) of sodium per dose, so it is essentially "sodium-free".

Motilium suspension contains sorbitol (E420). If your doctor has told you that you have an intolerance to some sugars, consult with them before taking this medicine. It may have a mild laxative effect because it contains 4.554 grams of sorbitol as an excipient per 10 milliliters. Sorbitol is a source of fructose. If your doctor has told you that you (or your child) have an intolerance to some sugars, or have been diagnosed with hereditary fructose intolerance (HFI), a rare genetic disorder, in which the patient cannot break down fructose, consult with your doctor before taking this medicine.

Sorbitol may cause gastrointestinal upset and a mild laxative effect.

Motilium suspension may cause allergic reactions (possibly delayed) and exceptionally, bronchospasm because it contains methyl p-hydroxybenzoate (E218) and propyl p-hydroxybenzoate (E216).

3. How to take Motilium

Follow the instructions for administration exactly, unless your doctor tells you otherwise.

Take Motilium before meals, as its absorption may be slightly delayed if taken after meals.

Duration of treatment

Symptoms usually resolve 3-4 days after taking this medicine. Do not take Motilium for more than 7 days without consulting your doctor.

Mix the contents of the bottle completely, making a gentle tilting motion to avoid foaming.

The bottle is protected by a child-resistant cap. To open it, press down on the plastic screw cap while turning it counterclockwise, as shown below.

Diagram of a hand applying pressure to an area of the abdomen marked with the number 1 and another area with the number 2

A measuring cup is provided with this medicine. This cup has marks for the following measures:

  • small cup: 1, 2, 3, and 4 ml
  • large cup: 5, 10, 15, and 20 ml

Make sure the mark on the measuring cup is at the top; this is where you should add the medicine (for example, it will contain 10 ml of oral suspension when filled to the line that indicates 10 ml of the large measuring cup).

Adults and adolescents 12 years of age and older and weighing 35 kg or more

  • Measure the required amount in the measuring cup.
  • Do not dilute Motilium and do not mix it with other liquids.
  • The usual dose is 10 milliliters administered up to three times a day, if possible before meals. Do not take more than 30 milliliters per day.
  • Clean the measuring cup after use.

If you take more Motilium than you should

If you have used or taken too much Motilium, contact your doctor, pharmacist, or poison control center immediately. In case of overdose, symptomatic treatment can be administered. ECG monitoring may be carried out due to the possibility of a heart problem called "prolonged QT interval".

In case of overdose or accidental ingestion, consult the Toxicology Information Service. Phone 91 562 04 20.

Information for the doctor: it is recommended to closely monitor the patient and take general supportive measures. Anticholinergic antiparkinsonian medicines may help counteract extrapyramidal effects.

If you forget to take Motilium

Take your medicine as soon as you remember. If it is almost time for your next dose, wait until then and continue with your regular schedule. Do not take a double dose to make up for the forgotten dose.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Uncommon(may affect up to 1 in 100 people):

  • Involuntary movements of the face or arms and legs, excessive tremor, excessive muscle stiffness, or muscle spasms

Frequency not known(cannot be estimated from the available data)

  • Seizures
  • A type of reaction that can occur immediately after administration and is characterized by skin rash, itching, shortness of breath, and/or swelling of the face
  • A severe allergic reaction that can occur immediately after administration, characterized by hives, itching, flushing, fainting, and difficulty breathing, among other possible symptoms
  • Cardiovascular disorders: heart rhythm disorders (fast or irregular heartbeat) have been reported; if this occurs, you should discontinue treatment immediately. Domperidone may be associated with an increased risk of heart rhythm disorders and cardiac arrest. This risk is more likely in patients over 60 years of age or in those taking doses higher than 30 mg/day. Domperidone should be used at the lowest effective dose.

Stop treatment with domperidone and contact your doctor immediatelyif you experience any of the side effects described above.

Other side effects observed with Motilium are listed below:

Common(may affect up to 1 in 10 people):

  • Dry mouth

Uncommon(may affect up to 1 in 100 people)

  • Anxiety
  • Agitation
  • Nervousness
  • Loss or decreased sexual interest
  • Headache
  • Drowsiness
  • Diarrhea
  • Skin rash
  • Itching
  • Hives
  • Pain or tenderness in the breasts
  • Discharge of milk from the breasts
  • General feeling of weakness
  • Feeling of dizziness

Frequency not known(cannot be estimated from the available data):

  • Rolling of the eyes
  • Stop of menstrual periods in women
  • Enlargement of the breasts in men
  • Difficulty urinating
  • Changes in the results of certain laboratory tests
  • Restless legs syndrome (uncomfortable feeling, with an irresistible urge to move your legs, and sometimes arms and other parts of your body).

Some patients who have taken Motilium for conditions and doses that require medical supervision have experienced the following side effects:

Restlessness; swelling or enlargement of the breasts, unusual discharge from the breasts, irregular menstrual periods in women, difficulty breastfeeding, depression, hypersensitivity.

Reporting of side effects

If you experience any side effects, talk to your doctor, pharmacist, or nurse, even if it is possible side effects not listed in this leaflet. You can also report side effects directly to the Spanish Medicines and Healthcare Products Agency (AEMPS) through the website: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storing Motilium

Keep out of the sight and reach of children.

Do not store above 30°C.

Do not use Motilium after the expiry date stated on the packaging. The expiry date "CAD" is the last day of the month indicated, where the first two digits indicate the month and the next ones, the year.

Medicines should not be disposed of via wastewater or household waste. Return the packaging and any unused medicine to a pharmacy for proper disposal. If in doubt, ask your pharmacist how to dispose of the packaging and any unused medicine. This will help protect the environment.

6. Contents of the pack and other information

Composition of Motilium

  • The active substance is domperidone.
  • The other ingredients are sodium saccharin (E954), microcrystalline cellulose (E460), sodium carboxymethylcellulose (E466), non-crystallizing liquid sorbitol (E420), methyl p-hydroxybenzoate (E218), propyl p-hydroxybenzoate (E216), polysorbate 20 (E432), sodium hydroxide, and purified water.

Appearance and packaging of the product

Homogeneous white suspension.

Each bottle contains 200 ml of suspension. The packaging includes a measuring cup.

Marketing Authorization Holder and Manufacturer

Marketing Authorization Holder

Esteve Pharmaceuticals, S.A.

Passeig de la Zona Franca, 109 08038 Barcelona

Spain

Manufacturer

TOWA Pharmaceutical Europe, S.L.

c/ de Sant Martí, 75-97 08107 Martorelles (Barcelona)

Spain

This leaflet was approved in May 2019

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Healthcare Products (AEMPS) http://www.aemps.gob.es/

Online doctors for MOTILIUM 1 mg/ml ORAL SUSPENSION

Discuss questions about MOTILIUM 1 mg/ml ORAL SUSPENSION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

4.4 (93)
Doctor

Tarek Agami

General medicine 11 years exp.

Dr. Tarek Agami is a general practitioner registered in both Portugal and Israel, with broad experience in family and preventive medicine. He offers online consultations for adults and children, providing personalised support for primary care needs, chronic disease management, and everyday health concerns.

Dr. Agami received clinical training and worked in leading medical institutions in Israel (Kaplan Medical Center, Barzilai Medical Center, Wolfson Medical Center) and Portugal (European Healthcare City, Viscura Internacional, Hospital Dr. José Maria Grande, Hospital Vila Franca de Xira). His approach combines international medical standards with individualised attention to each patient.

Main areas of consultation:

  • Diagnosis and treatment of acute and chronic conditions (high blood pressure, diabetes, respiratory infections, cardiovascular symptoms)
  • Evaluation of symptoms and guidance on further diagnostic testing
  • Preventive check-ups and regular health monitoring
  • Medical support during travel or after relocation
  • Treatment adjustments and lifestyle recommendations based on your personal history
Dr. Agami provides medical support for patients using GLP-1 medications (such as Ozempic or Mounjaro) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Portugal and Israel.

Dr. Agami is committed to evidence-based, patient-centred care, ensuring that each person receives trusted medical support tailored to their health goals.

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5.0 (40)
Doctor

Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
  • Structured support for undiagnosed complaints.
  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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€70
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Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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€58
5.0 (5)
Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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€80
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Doctor

Andrei Popov

General medicine 7 years exp.

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

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€80

Frequently Asked Questions

Is a prescription required for MOTILIUM 1 mg/ml ORAL SUSPENSION?
MOTILIUM 1 mg/ml ORAL SUSPENSION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in MOTILIUM 1 mg/ml ORAL SUSPENSION?
The active ingredient in MOTILIUM 1 mg/ml ORAL SUSPENSION is domperidone. This information helps identify medicines with the same composition but different brand names.
How much does MOTILIUM 1 mg/ml ORAL SUSPENSION cost in pharmacies?
The average pharmacy price for MOTILIUM 1 mg/ml ORAL SUSPENSION is around 3.15 EUR. Prices may vary depending on the manufacturer and dosage form.
Who manufactures MOTILIUM 1 mg/ml ORAL SUSPENSION?
MOTILIUM 1 mg/ml ORAL SUSPENSION is manufactured by Esteve Pharmaceuticals S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of MOTILIUM 1 mg/ml ORAL SUSPENSION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether MOTILIUM 1 mg/ml ORAL SUSPENSION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to MOTILIUM 1 mg/ml ORAL SUSPENSION?
Other medicines with the same active substance (domperidone) include DOMPERIDONE GAMIR 10 mg HARD CAPSULES, DOMPERIDONE PENSA 10 mg TABLETS, MOTILIUM 10 mg FILM-COATED TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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