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MELGAMA 300 MG FILM-COATED TABLETS

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use MELGAMA 300 MG FILM-COATED TABLETS

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

PACKAGE LEAFLET

Package Leaflet: Information for the Patient

Melgama 300mg film-coated tablets

benfotiamine

Read this package leaflet carefully before you start taking this medicine, as it contains important information for you.

Follow the instructions for administration of the medicine contained in this package leaflet or as indicated by your doctor or pharmacist.

  • Keep this package leaflet, as you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience side effects, consult your doctor or pharmacist, even if they are not listed in this package leaflet. See section 4.
  • You should consult a doctor if it worsens or does not improve.

Contents of the package leaflet

  1. What is Melgama and what is it used for
  2. What you need to know before taking Melgama
  3. How to take Melgama
  4. Possible side effects
  5. Storage of Melgama
  6. Package contents and additional information

1. What is Melgama and what is it used for

Melgama contains benfotiamine, which is a derivative of vitamin B1 that, after ingestion, is converted into vitamin B1.

Most people get enough vitamin B1 from their diet, but you may not absorb enough vitamin B1 if you have had stomach surgery, are on hemodialysis, have certain intestinal diseases, follow a restrictive diet, have diabetes or alcoholism, or are elderly.

Benfotiamine is used in adults in the following situations:

Treatment and prevention of vitamin B1 deficiency, if it cannot be controlled with an adequate diet.

This medicine is indicated for use in adults.

The tablets can be taken as long as symptoms persist or a dietary supplement is required; follow the recommendations of your doctor or pharmacist.

You should consult a doctor if it worsens or does not improve.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before taking Melgama

Do not take Melgama

If you are allergic to benfotiamine, thiamine, or any of the other components of this medicine (listed in section 6).

Warnings and precautions

Consult your doctor or pharmacist before starting to take Melgama.

Children and adolescents

This medicine must not be used in children and adolescents under 18 years of age, as the safety and benefits of this medicine in people under 18 years of age are not yet known.

Other medicines and Melgama

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicine.

5-fluorouracil, which is a chemotherapy medicine used to treat cancer, may reduce the action of vitamin B1.

Taking Melgama with food and drinks

There are no data on the influence of food on this medicine.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor before using this medicine.

Do not use this medicine unless it is prescribed by a doctor. Your doctor will only prescribe this medicine after carefully considering the risks and benefits. Your doctor will also consider other forms of vitamin B1 supplementation you may be taking (such as multivitamins before conception and during pregnancy).

The influence of benfotiamine on fertility is unknown.

Driving and using machines

Melgama has no significant influence on the ability to drive and use machines.

Melgama contains sodium

This medicine contains less than 1 mmol of sodium (23 mg) per film-coated tablet; it is essentially "sodium-free".

3. How to take Melgama

Follow the instructions for administration of the medicine contained in this package leaflet or as indicated by your doctor or pharmacist. If in doubt, ask your doctor or pharmacist.

Use in adults

Prevention:usually, half a tablet or one whole film-coated tablet (150-300 mg) once a day.

Treatment:1 film-coated tablet (300 mg) once a day.

Use in children and adolescents

This medicine is not suitable for use in children and adolescents under 18 years of age.

Elderly patients

The same dose as for adults is applied.

Renal impairment

In patients with kidney problems, this medicine can be used at the normal dose.

Hepatic impairment

It is unknown whether this medicine can be taken safely if you have liver problems. Consult your doctor if you have any liver problems.

Method of administration:

Oral use.

The tablet should be swallowed with a glass of water before meals.

The tablet can be divided into equal doses.

If you take more Melgama than you should

If you take more of this medicine than you should, consult your doctor or pharmacist, who will advise you on the necessary measures. No cases of benfotiamine overdose have been reported. In general, excess water-soluble vitamins, such as vitamin B1, are easily excreted in the urine, so no toxic effects of doses higher than recommended are expected.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone: 91 562 04 20, indicating the medicine and the amount ingested.

If you forget to take Melgama

Do not take a double dose to make up for forgotten doses.

If you stop taking Melgama

You should always consult your doctor or pharmacist before stopping treatment.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Frequency not known (cannot be estimated from the available data):

  • Allergic reactions (rash, itching, skin allergic reactions)
  • Nausea or other stomach or intestinal disorders

Reporting of side effects

If you experience any side effects, consult your doctor or pharmacist, even if they are not listed in this package leaflet. You can also report them directly through the Spanish Medicines Monitoring System, www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Melgama

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date stated on the carton or blister after EXP. The expiry date is the last day of the month indicated.

Store in the original packaging to protect from light.

Medicines should not be disposed of via wastewater or household waste. Dispose of the packaging and any unused medicine in the pharmacy's SIGRE point. If in doubt, ask your pharmacist how to dispose of the packaging and any unused medicine. This will help protect the environment.

6. Package contents and additional information

Composition of Melgama

  • The active ingredient is benfotiamine. Each tablet contains 300 mg of benfotiamine.
  • The other ingredients are: microcrystalline cellulose, talc, povidone K30, colloidal anhydrous silica, high-partial-glycerides, and sodium croscarmellose in the tablet core; and hypromellose 15 mPa·s, talc, titanium dioxide (E 171), hypromellose 3 mPa·s, hypromellose 6 mPa·s, hypromellose 50 mPa·s, macrogol 3350, and sodium saccharin in the film coating.

Appearance of the product and package contents

White, oblong, film-coated tablets with a break line on both sides (approx. dimensions 18.5 mm x 6.5 mm).

Melgama is available in blister packs (PVC/PVDC/Al) in a carton.

Packs of 1, 10, 30, 60, 90, or 100 film-coated tablets.

Clinical packs of 500, 1,000, or 5,000 film-coated tablets.

Not all pack sizes may be marketed.

Marketing authorisation holder and manufacturer

Marketing authorisation holder

AAA-Pharma GmbH

Flugfeld-Allee 24

71034 Böblingen

Germany

Manufacturer

Dragenopharm Apotheker Püschl GmbH

Göllstraße 1

84529 Tittmoning

Germany

This medicine is authorised in the Member States of the European Economic Area under the following names:

Austria milgamma protect 300 mg Filmtabletten

Spain Melgama 300 mg film-coated tablets

Date of the last revision of this package leaflet:03.2025.

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS): http://www.aemps.gob.es/

Online doctors for MELGAMA 300 MG FILM-COATED TABLETS

Discuss questions about MELGAMA 300 MG FILM-COATED TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (69)
Doctor

Tarek Agami

General medicine 11 years exp.

Dr. Tarek Agami is a general practitioner registered in both Portugal and Israel, with broad experience in family and preventive medicine. He offers online consultations for adults and children, providing personalised support for primary care needs, chronic disease management, and everyday health concerns.

Dr. Agami received clinical training and worked in leading medical institutions in Israel (Kaplan Medical Center, Barzilai Medical Center, Wolfson Medical Center) and Portugal (European Healthcare City, Viscura Internacional, Hospital Dr. José Maria Grande, Hospital Vila Franca de Xira). His approach combines international medical standards with individualised attention to each patient.

Main areas of consultation:

  • Diagnosis and treatment of acute and chronic conditions (high blood pressure, diabetes, respiratory infections, cardiovascular symptoms)
  • Evaluation of symptoms and guidance on further diagnostic testing
  • Preventive check-ups and regular health monitoring
  • Medical support during travel or after relocation
  • Treatment adjustments and lifestyle recommendations based on your personal history
Dr. Agami provides medical support for patients using GLP-1 medications (such as Ozempic or Mounjaro) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Portugal and Israel.

Dr. Agami is committed to evidence-based, patient-centred care, ensuring that each person receives trusted medical support tailored to their health goals.

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€69
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Doctor

Daniel Cichi

Family medicine 24 years exp.

Dr Daniel Cichi is a family medicine doctor with over 20 years of clinical experience. He provides online consultations for adults, supporting patients with acute symptoms, chronic conditions, and everyday health concerns that require timely medical guidance.

His background includes work in emergency care, ambulance services, and family medicine, which allows him to assess symptoms quickly, identify warning signs, and help patients choose the safest next steps – whether that means home care, treatment adjustment, or in-person evaluation.

Patients commonly consult Dr Daniel Cichi for:

  • acute symptoms: fever, infections, flu-like illness, cough, sore throat, shortness of breath;
  • chest discomfort, palpitations, dizziness, fatigue, and blood pressure concerns;
  • digestive problems: abdominal pain, nausea, diarrhoea, constipation, reflux;
  • muscle, joint, and back pain, minor injuries, post-traumatic symptoms;
  • chronic conditions: hypertension, diabetes, high cholesterol, thyroid disorders;
  • review and interpretation of lab tests, imaging reports, and medical documents;
  • medication review and treatment adjustment;
  • medical advice while travelling or living abroad;
  • second opinions and guidance on whether in-person care is needed.
Dr Cichi’s consultations are structured and practical. He focuses on clear explanations, risk assessment, and actionable recommendations, helping patients understand their symptoms and make informed decisions about their health.
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€55
5.0 (63)
Doctor

Nuno Tavares Lopes

Family medicine 18 years exp.

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

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€59
5.0 (17)
Doctor

Anastasiia Shalko

Family medicine 13 years exp.

Dr. Anastasiia Shalko is a general practitioner with a background in both paediatrics and general medicine. She graduated from Bogomolets National Medical University in Kyiv and completed her paediatric internship at the P.L. Shupyk National Medical Academy of Postgraduate Education. After working as a paediatrician in Kyiv, she relocated to Spain, where she has been practising general medicine since 2015, providing care for both adults and children.

Her work focuses on urgent, short-term medical concerns – situations where patients need quick guidance, symptom assessment and clear next steps. She helps people understand whether their symptoms require in-person evaluation, home management or a change in treatment. Common reasons for booking an online consultation include:

  • acute respiratory symptoms (cough, sore throat, runny nose, fever)
  • viral illnesses such as colds and seasonal infections
  • gastrointestinal complaints (nausea, diarrhoea, abdominal pain, gastroenteritis)
  • sudden changes in how a child or adult feels
  • questions about existing treatment and whether adjustments are needed
  • renewal of prescriptions when clinically appropriate
Dr. Shalko works specifically with urgent and short-term problems, providing practical recommendations and helping patients determine the safest next step. She explains symptoms clearly, guides patients through decision-making and offers straightforward medical advice for everyday acute issues.

She does not provide long-term management of chronic conditions, ongoing follow-up or comprehensive care plans for complex long-term illnesses. Her consultations are designed for acute symptoms, sudden concerns and situations where timely medical input is important.

With clinical experience in both paediatrics and general medicine, Dr. Shalko confidently supports adults and children. Her communication style is clear, simple and reassuring, helping patients feel informed and supported throughout the consultation.

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€50

Frequently Asked Questions

Is a prescription required for MELGAMA 300 MG FILM-COATED TABLETS?
MELGAMA 300 MG FILM-COATED TABLETS does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in MELGAMA 300 MG FILM-COATED TABLETS?
The active ingredient in MELGAMA 300 MG FILM-COATED TABLETS is benfotiamine. This information helps identify medicines with the same composition but different brand names.
Who manufactures MELGAMA 300 MG FILM-COATED TABLETS?
MELGAMA 300 MG FILM-COATED TABLETS is manufactured by Aaa-Pharma Gmbh. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of MELGAMA 300 MG FILM-COATED TABLETS online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether MELGAMA 300 MG FILM-COATED TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to MELGAMA 300 MG FILM-COATED TABLETS?
Other medicines with the same active substance (benfotiamine) include BENERVA 100 mg/ml INJECTABLE SOLUTION, BENERVA 300 mg FILM-COATED TABLETS, SURMENALIT 200 mg FILM-COATED TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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