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FYREMADEL 0.25 MG / 0.5 ML INJECTABLE SOLUTION IN PRE-FILLED SYRINGE EFG

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Doctor

Nuno Tavares Lopes

Family medicine 18 years exp.

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use FYREMADEL 0.25 MG / 0.5 ML INJECTABLE SOLUTION IN PRE-FILLED SYRINGE EFG

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Fyremadel0.25 mg/0.5 ml solution for injection in pre-filled syringe EFG

Ganirelix

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor, pharmacist, or nurse.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack and other information

  1. What is Fyremadel and what is it used for
  2. What you need to know before you use Fyremadel
  3. How to use Fyremadel
  4. Possible side effects
  5. Storage of Fyremadel

Contents of the pack and further information

1. What is Fyremadel and what is it used for

Fyremadel contains the active substance ganirelix and belongs to a group of medicines called “gonadotropin-releasing hormone antagonists” that acts against the action of the endogenous gonadotropin-releasing hormone (GnRH). GnRH regulates the release of gonadotropins (luteinizing hormone (LH) and follicle-stimulating hormone (FSH)). The gonadotropins play an important role in human fertility and reproduction. FSH is necessary in women for the growth and development of follicles in the ovaries. The follicles are small, rounded vesicles that contain the eggs. LH is necessary for the release of mature eggs from the ovarian follicles (i.e., ovulation). Fyremadel inhibits the action of GnRH, which causes the suppression of the release of LH in particular.

What Fyremadel is used for

In women undergoing assisted reproduction techniques, such as in-vitro fertilization (IVF) and other methods, premature ovulation may occasionally occur, which significantly reduces the probability of becoming pregnant. Fyremadel is used to prevent the premature release of LH, which can cause premature ovulation.

In clinical studies, Fyremadel was used with recombinant follicle-stimulating hormone (FSH) or with corifollitropin alfa, a long-acting follicular stimulant.

Doctor consultation

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2. What you need to know before you use Fyremadel

Do not useFyremadel

  • if you are allergic to ganirelix or any of the other ingredients of this medicine (listed in section 6);
  • if you are hypersensitive to gonadotropin-releasing hormone (GnRH) or its analogs;
  • if you have moderate or severe kidney or liver disease;
  • if you are pregnant or breastfeeding.

Warnings and precautions

Consult your doctor, pharmacist, or nurse before starting treatment with Fyremadel:

  • If you have an active allergy, inform your doctor. Your doctor will decide, depending on the severity, if additional monitoring is needed during treatment. Allergic reactions have been observed, even after the first dose.
  • Allergic reactions, both generalized and localized, including hives (urticaria), swelling of the face, lips, tongue, and/or throat that can cause difficulty breathing and/or swallowing (angioedema and/or anaphylaxis) (see also section 4). If you have an allergic reaction, stop using Fyremadel and seek medical attention immediately.
  • Latex allergy: the needle shield contains dry natural rubber/latex, which may cause allergic reactions when in contact with the needle.
  • During or after hormonal stimulation of the ovaries, ovarian hyperstimulation syndrome (OHSS) may develop. This syndrome is related to the gonadotropin stimulation procedure. We recommend that you read the package leaflet of the gonadotropin medicine that you have been prescribed.
  • The incidence of congenital malformations after the use of assisted reproduction techniques may be slightly higher than after spontaneous conceptions. It is considered that this slightly higher incidence is related to the characteristics of patients undergoing fertility treatments (e.g., woman's age, semen characteristics) and the higher incidence of multiple pregnancies recorded after the use of assisted reproduction techniques. The incidence of congenital malformations after the use of assisted reproduction techniques with Fyremadel is not different from the incidence with the use of other GnRH analogs in assisted reproduction techniques.
  • There is a slight increase in the risk of an ectopic pregnancy (a pregnancy that develops outside the uterus) in women with damaged Fallopian tubes.
  • The efficacy and safety of Fyremadel have not been established in women who weigh less than 50 kg or more than 90 kg. Consult your doctor for more information.

Children and adolescents

Fyremadel is not intended for use in children or adolescents.

Using Fyremadel with other medicines

Tell your doctor or pharmacist if you are using, have recently used, or might use any other medicines.

Pregnancy, breastfeeding, and fertility

Fyremadel should be used during controlled ovarian stimulation for assisted reproduction techniques (ART). Do not use Fyremadel during pregnancy and breastfeeding.

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.

Driving and using machines

No studies on the effects on the ability to drive and use machines have been performed.

Fyremadel contains sodium

This medicine contains less than 1 mmol of sodium (23 mg) per injection, which is essentially "sodium-free".

3. How to use Fyremadel

Fyremadel is used as part of the treatment in assisted reproduction techniques (ART), including in-vitro fertilization (IVF).

You will administer the injections yourself, so your doctor should explain how to do it. Follow exactly the administration instructions of this medicine indicated by your doctor or pharmacist. If in doubt, consult your doctor or pharmacist again.

Phase 1

Ovarian stimulation with follicle-stimulating hormone (FSH) or corifollitropin alfa may start on the second or third day of your menstruation.

Phase 2

The contents of the Fyremadel syringe (0.25 mg) should be injected once a day just under the skin, starting on the fifth or sixth day of stimulation. Depending on your ovarian response, your doctor may decide to start on another day.

Fyremadel and FSH should be administered approximately at the same time. However, these medicines should not be mixed and should be injected in different locations.

Daily treatment with Fyremadel should continue until there are enough follicles of adequate size.

Phase 3

The final maturation of the eggs in the follicles can be induced by administering human chorionic gonadotropin (hCG). The time between two Fyremadel injections and between the last Fyremadel injection and the hCG injection should not exceed 30 hours; otherwise, premature ovulation (i.e., release of the eggs) may occur. Therefore, if the Fyremadel injection is given in the morning, Fyremadel treatment should be maintained throughout the entire gonadotropin treatment period, including the day of ovulation induction. If the Fyremadel injection is given in the afternoon, the last Fyremadel injection should be administered on the evening before the day of ovulation induction.

Instructions for use

Injection site

Fyremadel is presented in pre-filled syringes that contain a dose. The contents of the syringe should be injected slowly just under the skin, preferably in the thigh. Check the solution before use. Do not use the solution if it contains particles or is not transparent. If you or your partner administer the injections, follow the instructions below carefully. Do not mix Fyremadel with other medicines.

Front view of the lower abdomen with two shaded oval areas indicating the recommended injection sites

Preparing the injection site

Wash your hands thoroughly with water and soap. The injection site should be cleaned with a disinfectant (e.g., alcohol) to remove bacteria from the surface. Clean an area of about 5 cm around the injection point and let the disinfectant dry for at least one minute before injecting.

Hands holding a transparent vial with liquid and a needle inserted into the rubber stopper

Inserting the needle

Remove the needle cap. Pinch a large area of skin between your index and thumb fingers. Insert the needle into the base of the pinched skin at an angle of 45° with respect to the skin surface. The injection site should be varied for each injection.

Hand holding a syringe with needle, showing the pinched skin fold for subcutaneous injectionHand administering intramuscular injection in the arm, 45-degree angle, smooth skin, and outlined technique for drug administrationHand holding a syringe with needle inserted into the skin at an angled position for subcutaneous injection

Checking the correct position of the needle

Gently pull back the plunger to check if the needle is correctly positioned. If blood enters the syringe, it means that the needle tip has penetrated a blood vessel. If this happens, do not inject Fyremadel; instead, remove the syringe, cover the injection site with a swab with disinfectant, and press; it should stop bleeding within one or two minutes. Do not use this syringe and dispose of it properly. Start again with a new syringe.

Injecting the solution

Once the needle is correctly positioned, press the plunger slowly and constantly to inject the solution correctly and avoid damaging the skin tissues.

Removing the syringe

Remove the syringe quickly and press on the injection site with a swab with disinfectant.

Use the pre-filled syringe only once.

Hand holding a syringe with needle inserted into the arm skin, showing the injection angle

If you use more Fyremadel than you should

Consult your doctor. In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone: 91 562 04 20, indicating the medicine and the amount taken.

If you forget to use Fyremadel

If you realize you have forgotten to inject a dose, administer it as soon as possible.

Do not take a double dose to make up for forgotten doses.

If you delay more than 6 hours (i.e., the interval between two injections is prolonged more than 30 hours), administer the dose as soon as possible andconsult your doctor for advice.

If you stop using Fyremadel

Do not stop using Fyremadel unless your doctor tells you to, as this may affect the outcome of your treatment.

If you have any further questions on the use of this medicine, ask your doctor, pharmacist, or nurse.

Medicine questions

Started taking the medicine and have questions?

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4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Very common (may affect up to 1 in 10 women)

  • local reactions at the injection site (mainly redness, with or without swelling). The local reaction usually disappears within 4 hours after administration.

Uncommon (may affect up to 1 in 100 women)

  • headache
  • nausea
  • malaise (general feeling of being unwell, feeling sick).

Very rare (may affect up to 1 in 10,000 women)

  • allergic reactions have been observed, even after the first dose, including rash
  • facial swelling
  • difficulty breathing (dyspnea)
  • swelling of the face, lips, tongue, and/or throat, which can cause difficulty breathing and/or swallowing (angioedema and/or anaphylaxis)
  • hives (urticaria).

In addition, side effects related to controlled ovarian hyperstimulation treatment have been observed, such as:

  • abdominal pain,
  • ovarian hyperstimulation syndrome (OHSS), (OHSS occurs when the ovaries react excessively to the fertility medicines you are taking)
  • ectopic pregnancy (when the embryo develops outside the uterus)
  • miscarriage (see the package leaflet of the medicine with FSH that you are using).

After the first dose of Fyremadel, worsening of a pre-existing eczema has been reported in one patient.

Reporting of side effects

If you experience any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly to the Spanish Medicines Agency (AEMPS) at https://www.notificaram.es.

By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Fyremadel

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton after ‘EXP’. The expiry date refers to the last day of that month.

This medicine does not require any special storage conditions.

Inspect the syringe before use. The syringe should only be used if the solution is transparent and particle-free and the container is not damaged.

Medicines should not be disposed of via wastewater or household waste. Return any unused medicine to a pharmacy for proper disposal. If you are unsure, ask your pharmacist how to dispose of unused medicines. This will help protect the environment.

6. Contents of the pack and further information

Composition of Fyremadel

  • The active substance is ganirelix. Each pre-filled syringe contains 0.25 mg of ganirelix (as acetate) in 0.5 ml of aqueous solution.
  • The other ingredients are glacial acetic acid (E260), mannitol (E421), and water for injections. The pH may have been adjusted with sodium hydroxide and glacial acetic acid.

Appearance and pack contents

Fyremadel is a clear and colorless aqueous solution for injection. The solution is ready to use and is administered subcutaneously. The needle shield contains dry natural rubber/latex, which is in contact with the needle.

Fyremadel is available in packs of 1 or 5 pre-filled syringes with injection needles (27 G).

Not all pack sizes may be marketed.

Marketing authorization holder and manufacturer

Sun Pharmaceutical Industries Europe B.V.

Polarisavenue 87

2132 JH Hoofddorp

Netherlands

You can obtain further information on this medicine from the representative of the marketing authorization holder:

FERRING S.A.U.

C/Arquitecto Sánchez Arcas nº 3 1º28040, Madrid, Spain

This medicine is authorized in the Member States of the European Economic Area under the following names:

Austria: Fyremadel 0,25 mg/0,5 ml Injektionslösung in einer Fertigspritze

Denmark: Fyremadel 0,25 mg/0,5 ml injektionsvæske, opløsning i fyldt injektionssprøjte

Spain: Fyremadel 0,25 mg/0,5 ml solución inyectable en jeringa precargada EFG

Finland: Fyremadel 0,25 mg/0,5 ml injektioneste, liuos esitäytetty ruisku

France: Fyremadel 0,25 mg/0,5 ml solution injectable en seringue pré-remplie

Germany: Fyremadel 0,25 mg/0,5 ml Injektionslösung in einer Fertigspritze

Italy: Fyremadel 0,25 mg/0,5 ml soluzione iniettabile in siringa preriempita

Netherlands: Fyremadel 0,25 mg/0,5 ml oplossing voor injectie in voorgevulde spuit

Norway: Fyremadel 0,25 mg/0,5 ml injeksjonsvæske, oppløsning, i ferdigfylt sprøyte

Sweden: Fyremadel 0,25 mg/0,5 ml injektionsvätska, lösning, förfylld spruta

United Kingdom: Fyremadel 0.25 mg/0.5 ml solution for injection in pre-filled syringe

Date of last revision of this leaflet:April 2020

Detailed and up-to-date information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/.

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Discuss questions about FYREMADEL 0.25 MG / 0.5 ML INJECTABLE SOLUTION IN PRE-FILLED SYRINGE EFG, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Daniel Cichi

Family medicine 24 years exp.

Dr Daniel Cichi is a family medicine doctor with over 20 years of clinical experience. He provides online consultations for adults, supporting patients with acute symptoms, chronic conditions, and everyday health concerns that require timely medical guidance. His background includes work in emergency care, ambulance services, and family medicine, which allows him to assess symptoms quickly, identify warning signs, and help patients choose the safest next steps – whether that means home care, treatment adjustment, or in-person evaluation. Patients commonly consult Dr Daniel Cichi for: 

  • acute symptoms: fever, infections, flu-like illness, cough, sore throat, shortness of breath;
  • chest discomfort, palpitations, dizziness, fatigue, and blood pressure concerns;
  • digestive problems: abdominal pain, nausea, diarrhoea, constipation, reflux;
  • sexually transmitted infections, erectile dysfunction;
  • muscle, joint, and back pain, minor injuries, post-traumatic symptoms;
  • chronic conditions: hypertension, diabetes, high cholesterol, thyroid disorders, weight loss, hair loss;
  • review and interpretation of lab tests, imaging reports, and medical documents;
  • medication review and treatment adjustment;
  • medical advice while travelling or living abroad;
  • second opinions and guidance on whether in-person care is needed.

Dr Cichi’s consultations are structured and practical. He focuses on clear explanations, risk assessment, and actionable recommendations, helping patients understand their symptoms and make informed decisions about their health.

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Andreea Mateescu

Paediatrics 8 years exp.

Dr Andreea Mateescu is a board-certified paediatrician with 7 years of clinical experience. She graduated from Carol Davila University of Medicine and Pharmacy in Bucharest, Romania, and completed her paediatric residency at INSMC Alessandrescu-Rusescu. She also holds additional training in general ultrasound diagnostics.

Dr Mateescu focuses on providing high-quality, evidence-based medical care for children, with a strong emphasis on prevention, healthy development, and long-term wellbeing. She believes that clear, empathetic communication with both children and parents is essential for building trust and ensuring effective care.

Online consultations with Dr Mateescu are suitable for:

  • preventive check-ups and monitoring of growth and development;
  • vaccination planning, including personalised and catch-up schedules;
  • assessment of psychomotor, emotional, and physical development;
  • diagnosis and management of acute and chronic paediatric conditions;
  • nutritional guidance for infants and children, including formula selection when medically indicated;
  • care for children with complex or rare conditions;
  • practical guidance and ongoing support for parents.
Dr Mateescu works with patience, empathy, and professionalism, ensuring that each child receives attentive, individualised care. Her goal is to support healthy, balanced development while helping parents feel confident and well-informed at every stage of their child’s care.
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Nuno Tavares Lopes

Family medicine 18 years exp.

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

5.0 (73)
Doctor

Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
  • Structured support for undiagnosed complaints.
  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

4.6 (73)
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Anastasiia Shalko

Family medicine 13 years exp.

Dr. Anastasiia Shalko is a general practitioner with a background in both paediatrics and general medicine. She graduated from Bogomolets National Medical University in Kyiv and completed her paediatric internship at the P.L. Shupyk National Medical Academy of Postgraduate Education. After working as a paediatrician in Kyiv, she relocated to Spain, where she has been practising general medicine since 2015, providing care for both adults and children.Her work focuses on urgent, short-term medical concerns – situations where patients need quick guidance, symptom assessment and clear next steps. She helps people understand whether their symptoms require in-person evaluation, home management or a change in treatment. Common reasons for booking an online consultation include:

  • acute respiratory symptoms (cough, sore throat, runny nose, fever)
  • viral illnesses such as colds and seasonal infections
  • gastrointestinal complaints (nausea, diarrhoea, abdominal pain, gastroenteritis)
  • sudden changes in how a child or adult feels
  • questions about existing treatment and whether adjustments are needed
  • renewal of prescriptions when clinically appropriate

Dr. Shalko works specifically with urgent and short-term problems, providing practical recommendations and helping patients determine the safest next step. She explains symptoms clearly, guides patients through decision-making and offers straightforward medical advice for everyday acute issues.She does not provide long-term management of chronic conditions, ongoing follow-up or comprehensive care plans for complex long-term illnesses. Her consultations are designed for acute symptoms, sudden concerns and situations where timely medical input is important.With clinical experience in both paediatrics and general medicine, Dr. Shalko confidently supports adults and children. Her communication style is clear, simple and reassuring, helping patients feel informed and supported throughout the consultation.

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Lisa Drigo

Paediatrics 34 years exp.

Dr Lisa Drigo is an experienced paediatrician based in Italy with over 30 years of clinical practice. She graduated from Università Cattolica del Sacro Cuore in Rome and has spent decades working within the Italian healthcare system, supporting children and families with both acute care and long-term prevention.

She is well familiar with Italian paediatric standards, including local vaccination schedules, preventive check-ups, growth monitoring, and everyday medical issues faced by families living in Italy. This makes her consultations especially valuable for parents who want guidance that aligns with local medical practice.

Her primary focus is paediatrics, with additional support in family medicine when a child’s health needs to be assessed in a broader family or preventive context.

Patients most often consult her for:

  • Acute infections in children (fever, cough, sore throat, runny nose).
  • Viral and bacterial illnesses, frequent colds.
  • Digestive symptoms such as abdominal pain, nausea, diarrhoea or constipation.
  • Monitoring of growth, weight, and developmental milestones.
  • Vaccination advice according to Italian schedules.
  • Allergic reactions, skin rashes, food sensitivities.
  • General health concerns and everyday questions from parents.
  • Preventive care, nutrition advice, and healthy lifestyle guidance.

Dr Drigo communicates in a clear, calm, and reassuring way, helping parents understand what is happening and what steps to take next. Online consultations allow families to receive reliable paediatric guidance aligned with Italian medical practice, without unnecessary stress or waiting.

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Lizaveta Trafimchuk Takhvaniuk

Dermatology 10 years exp.

Dr. Lizaveta Trafimchuk Takhvaniuk graduated in Medicine and subsequently specialized in Dermatology and Venereology. She has more than 10 years of clinical experience and is licensed to practice in Spain, where she focuses on the comprehensive diagnosis and treatment of dermatological conditions.

Throughout her education and professional career, Dr. Trafimchuk has gained extensive experience in managing diseases of the skin, hair, and nails, as well as in the diagnosis, treatment, and prevention of sexually transmitted infections (STIs). Her clinical approach is based on evidence-based medicine, combined with personalized care tailored to each patient’s needs.

In her daily practice, she treats a wide range of dermatological conditions, including chronic inflammatory dermatoses such as acne, rosacea, atopic dermatitis, psoriasis, and eczema. She also has experience in treating pigmentation disorders, including melasma, post-inflammatory hyperpigmentation, and dyschromia.

She has developed a particular interest in trichology, treating various types of alopecia, chronic hair loss, and scalp disorders. In addition, she has experience in managing infectious dermatoses of fungal, viral, and bacterial origin, as well as in evaluating benign and suspicious skin lesions, with referral to specialized care when necessary.

With a strong interest in a comprehensive approach to skin health, she also treats scars, post-procedural skin changes, and conditions related to hormonal factors and aging, including those associated with pregnancy, menopause, and age-related skin changes.

Thanks to her experience and continuous professional development, Dr. Trafimchuk provides high-quality medical care that is professional, confidential, and aligned with modern dermatology standards.

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Joao Silva

General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

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Frequently Asked Questions

Is a prescription required for FYREMADEL 0.25 MG / 0.5 ML INJECTABLE SOLUTION IN PRE-FILLED SYRINGE EFG?

FYREMADEL 0.25 MG / 0.5 ML INJECTABLE SOLUTION IN PRE-FILLED SYRINGE EFG requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in FYREMADEL 0.25 MG / 0.5 ML INJECTABLE SOLUTION IN PRE-FILLED SYRINGE EFG?

The active ingredient in FYREMADEL 0.25 MG / 0.5 ML INJECTABLE SOLUTION IN PRE-FILLED SYRINGE EFG is ganirelix. This information helps identify medicines with the same composition but different brand names.

Who manufactures FYREMADEL 0.25 MG / 0.5 ML INJECTABLE SOLUTION IN PRE-FILLED SYRINGE EFG?

FYREMADEL 0.25 MG / 0.5 ML INJECTABLE SOLUTION IN PRE-FILLED SYRINGE EFG is manufactured by Sun Pharmaceutical Industries (Europe) B.V.. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of FYREMADEL 0.25 MG / 0.5 ML INJECTABLE SOLUTION IN PRE-FILLED SYRINGE EFG online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether FYREMADEL 0.25 MG / 0.5 ML INJECTABLE SOLUTION IN PRE-FILLED SYRINGE EFG is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy FYREMADEL 0.25 MG / 0.5 ML INJECTABLE SOLUTION IN PRE-FILLED SYRINGE EFG in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy FYREMADEL 0.25 MG / 0.5 ML INJECTABLE SOLUTION IN PRE-FILLED SYRINGE EFG in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to FYREMADEL 0.25 MG / 0.5 ML INJECTABLE SOLUTION IN PRE-FILLED SYRINGE EFG?

Other medicines with the same active substance (ganirelix) include ASTARTE 0.25 mg/0.5 mL Injectable Solution in Pre-filled Syringe, GANIRELIX GEDEON RICHTER 0.25 mg/0.5 ml Injectable Solution in Pre-filled Syringe EFG, ORGALUTRAN 0.25 mg/0.5 mL Injectable Solution. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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