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FRISPEC 6.5 mg/ml SYRUP

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About the medicine

How to use FRISPEC 6.5 mg/ml SYRUP

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

PACKAGE LEAFLET: Information for the user

frispec 6.5 mg/ml Syrup

Guaifenesin

Read this leaflet carefully before you start taking this medicine because it contains important information for you.

Follow the administration instructions of the medicine contained in this leaflet or as indicated by your doctor or pharmacist.

  • Keep this leaflet, as you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience side effects, consult your doctor or pharmacist even if they are not listed in this leaflet.
  • You should consult a doctor if your condition worsens or does not improve after 7 days of treatment.

Contents of the package leaflet:

  1. What is frispec and what is it used for
  2. What you need to know before taking frispec
  3. How to take frispec
  4. Possible side effects
  5. Storage of frispec
  6. Package contents and additional information

1. What is frispec and what is it used for

Guaifenesin, the active ingredient of this medicine, belongs to the group of medicines called expectorants.

It is indicated to relieve productive cough by reducing phlegm (mucus) and facilitating its expulsion.

For adults and children over 2 years old.

You should consult a doctor if your condition worsens or does not improve after 7 days of treatment.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before taking frispec

Do not take frispec:

  • If you are allergic to guaifenesin or any of the other components of this medicine (listed in section 6)
    • Children under 2 years old cannot take this medicine.

Warnings and precautions:

Consult your doctor, pharmacist, or nurse before taking Frispec if:

  • You have had a cough for more than 7 days or if your cough is recurrent or accompanied by fever, rash, or persistent headache
  • You have a persistent cough that may be caused by asthma
  • You have a cough with a large amount of mucus (phlegm)
  • You have severe liver or kidney problems

Interference with laboratory tests

If you are going to have a urine test, it is essential that you inform your doctor or nurse that you are taking or have recently taken this medicine, as it may alter some results.

Children

Children under 2 years old cannot take this medicine because it is contraindicated.

Taking frispec with other medicines:

Inform your doctor or pharmacist if you are taking, have recently taken, or may need to take any other medicine.

It is not recommended to take this medicine with other cough medicines (antitussives or cough suppressants)

Taking frispec with food, drinks, and alcohol:

You can take this medicine with or without food.

Do not drink alcohol while being treated with this medicine.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

This medicine should not be used during pregnancy unless your doctor prescribes it.

Do not take this medicine if you are breastfeeding unless your doctor prescribes it.

Driving and using machines:

If you experience dizziness during treatment with this medicine, do not drive or use machines.

frispec contains sucrose, methyl parahydroxybenzoate, glycerol, sodium benzoate, and sodium

This medicine contains sucrose. If your doctor has told you that you have an intolerance to certain sugars, consult with them before taking this medicine.

Patients with diabetes mellitus should note that this medicine contains 9.75 g of sucrose per 15 ml.

It may cause allergic reactions (possibly delayed) because it contains methyl parahydroxybenzoate (E-218).

This medicine may cause headache, stomach upset, and diarrhea because it contains glycerol.

This medicine contains 0.1 g of benzoic acid salt per unit volume, equivalent to 0.1 g / weight volume.

This medicine contains less than 1 mmol of sodium (23 mg) per unit volume; that is, it is essentially "sodium-free".

3. How to take frispec

Follow the administration instructions of the medicine contained in this leaflet or as indicated by your doctor, pharmacist, or nurse. In case of doubt, consult your doctor, pharmacist, or nurse.

The recommended dose is:

Adults and adolescents over 12 years old: administer 30 ml (195 mg) every 4 hours if necessary.

Over 65 years old: the same as for adults.

Patient with kidney/liver disease: should consult a doctor.

Use in children

Children from 6 to 12 years old: administer 15 ml (97.5 mg) every 4 hours if necessary.

Children from 2 to 5 years old: administer under medical control 7.5 ml (48.75 mg) every 4 hours if necessary.

Children under 2 years old: it is contraindicated

Method of administration

This medicine is taken orally.

Shake the bottle before use. Measure the amount to be taken with the measuring spoon provided with the package.

The syrup can be taken alone or mixed with water. You should take a glass of water after taking each dose.

You should consult a doctor if your condition worsens or does not improve after 7 days of treatment

If you take more frispec than you should:

If you take more medicine than you should, you may experience stomach upset, nausea, diarrhea, and drowsiness.

Prolonged and high-dose use of this medicine may produce kidney stones.

In case of overdose or accidental ingestion, consult your doctor, go to a medical center, or call the Toxicology Information Service (phone: 91 562 04 20), indicating the medicine and the amount ingested.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, frispec can cause side effects, although not everyone gets them.

The following may occur: nausea, vomiting, diarrhea, stomach upset, headache, and dizziness.

If you experience any of the following side effects, stop taking this medicine and consult your doctor immediately:

  • Allergic reactions including skin rash (which can be severe, with blisters, abrasion, and peeling of the skin) and itching.

Reporting side effects:

If you experience any side effects, consult your doctor, pharmacist, or nurse, even if they are not listed in this leaflet. You can also report them directly through the Spanish Medicines and Healthcare Products Agency (AEMPS) website: http://www.aemps.gob.es/

5. Storage of frispec

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiration date stated on the package after CAD. The expiration date is the last day of the month indicated.

No special storage conditions are required.

Medicines should not be disposed of via wastewater or household waste. Deposit the packages and medicines you no longer need at the SIGRE point in your pharmacy. If in doubt, ask your pharmacist how to dispose of packages and medicines you no longer need. This will help protect the environment.

6. Package contents and additional information

Composition of frispec:

  • The active ingredient is guaifenesin. Each ml of syrup contains 6.5 mg of guaifenesin
  • The other ingredients (excipients) are methyl parahydroxybenzoate (E-218), anise essence, pine essence, sodium benzoate (E-211), sucrose, glycerol (E-422), sodium saccharin, and purified water.

Appearance of the product and package contents

Transparent oral solution with anise flavor. frispec is presented in a bottle containing 150 ml.

Marketing authorization holder

Farline Comercializadora de Productos Farmacéuticos, S.A.

C/ Santa Engracia, 31

28010 – Madrid (Spain)

Manufacturer

ALCALÁ FARMA, S.L.

Avenida de Madrid 82,

Alcala de Henares. 28802. Spain

Date of the last revision of this leaflet:September 2022

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Healthcare Products (AEMPS) http://www.aemps.gob.es/

Online doctors for FRISPEC 6.5 mg/ml SYRUP

Discuss questions about FRISPEC 6.5 mg/ml SYRUP, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (29)
Doctor

Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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5.0 (29)
Doctor

Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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Doctor

Svetlana Kolomeeva

Cardiology 18 years exp.

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

  • High blood pressure, headaches, dizziness, swelling, palpitations.
  • Diagnosis and management of hypertension, arrhythmias, and tachycardia.
  • Metabolic syndrome, excess weight, high cholesterol.
  • Chronic fatigue, insomnia, poor concentration, anxiety.
  • Respiratory symptoms: colds, flu, sore throat, cough, fever.
  • Digestive issues: heartburn, bloating, constipation, IBS symptoms.
  • Chronic conditions: diabetes, thyroid disorders.
  • Interpretation of lab tests and medical reports, therapy adjustment.
  • Second opinion and decision-making support.
  • Cardiovascular disease prevention and metabolic risk reduction.
  • Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

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5.0 (2)
Doctor

Alexander Nazarchuk

Allergology 7 years exp.

Dr. Alexander Nazarchuk is a physician specialising in allergology and internal medicine. He provides online consultations for adults, following the principles of evidence-based medicine — no outdated treatments or unnecessary tests, with clear explanations and a personalised approach. He helps patients with a wide range of allergic and therapeutic conditions, from common day-to-day complaints to complex cases involving allergies, gastrointestinal issues, cardiovascular concerns, respiratory symptoms, and more.

You can consult Dr. Nazarchuk for:

  • Test interpretation and guidance on diagnostic plans.
  • Allergic rhinitis, hay fever, bronchial asthma (including severe cases).
  • Food and drug allergies, skin rashes, angioedema.
  • Atopic dermatitis, urticaria, contact allergies.
  • Allergen-specific immunotherapy (AIT) – initiation and ongoing management.
  • Abdominal pain, bloating, changes in bowel habits, nausea, heartburn.
  • High blood pressure and adjustment of baseline antihypertensive therapy.
  • Hyperlipidaemia and elevated cholesterol.
  • Cough, nasal congestion, fever, sore throat.
  • Anaemia, including iron deficiency and related conditions.
  • Other issues related to allergology and internal medicine.

During consultations, Dr. Nazarchuk takes a thorough, structured approach — analysing symptoms, identifying potential causes, and helping patients make informed decisions. Whether treatment, further investigation, or monitoring is needed, he explains each step clearly so you understand your health and how best to manage it.

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€55

Frequently Asked Questions

Is a prescription required for FRISPEC 6.5 mg/ml SYRUP?
FRISPEC 6.5 mg/ml SYRUP does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in FRISPEC 6.5 mg/ml SYRUP?
The active ingredient in FRISPEC 6.5 mg/ml SYRUP is guaifenesin. This information helps identify medicines with the same composition but different brand names.
Who manufactures FRISPEC 6.5 mg/ml SYRUP?
FRISPEC 6.5 mg/ml SYRUP is manufactured by Farline Comercializadora De Productos Farmaceuticos S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of FRISPEC 6.5 mg/ml SYRUP online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether FRISPEC 6.5 mg/ml SYRUP is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to FRISPEC 6.5 mg/ml SYRUP?
Other medicines with the same active substance (guaifenesin) include FORMULAEXPEC 13.33 mg/ml SYRUP HONEY FLAVORED, INISTON MUCOSIDAD 20mg/ml ORAL SOLUTION MINT FLAVOR, ABRILAR SYRUP. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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