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DOXIUM FUERTE 500 mg HARD CAPSULES

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About the medicine

How to use DOXIUM FUERTE 500 mg HARD CAPSULES

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Doxium Fuerte 500 mg Hard Capsules

Calcium Dobesilate

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the Package Leaflet

  1. What is Doxium Fuerte and what is it used for
  2. What you need to know before you take Doxium Fuerte
  3. How to take Doxium Fuerte
  4. Possible side effects
  5. Storage of Doxium Fuerte
  6. Contents of the pack and other information

1. What is Doxium Fuerte and what is it used for

Doxium Fuerte is presented in the form of hard capsules. Each pack contains 60 hard capsules of 500 mg each.

Doxium Fuerte is a medicine that contains a substance called calcium dobesilate, which regulates the functions of the blood capillaries and also acts on the components of the blood. Its direct biological activity involves the release of a vasodilator substance (nitric oxide) that helps to improve microcirculatory disorders.

Doxium Fuerte is indicated for eye disorders caused by diabetes, such as non-proliferative diabetic retinopathy.

Doctor consultation

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2. What you need to know before you take Doxium Fuerte

Do not take Doxium Fuerte

  • if you are allergic to the active substance or to any of the other ingredients of this medicine.

Warnings and precautions

Consult your doctor before taking Doxium Fuerte:

  • If you have kidney failure, as you may need a dose adjustment, especially if you have severe kidney failure that requires dialysis.
  • If you have any symptoms or signs of infection, such as fever, inflammation of the mucous membranes at the level of the palate, tonsils, tongue. In these cases, it is recommended to suspend treatment. Your doctor may recommend that you have a blood test.
  • If you have liver failure, as you may need a dose adjustment.
  • If you are going to have laboratory tests (e.g., blood tests), as calcium dobesilate may interfere with the results (e.g., creatinine). Laboratory tests should be performed before the daily intake of the drug.

Be careful with Doxium Fuerte

Like other medicines, Doxium Fuerte can cause severe hypersensitivity reactions (or allergic reactions). If you experience any such reaction, treatment should be discontinued.

Calcium dobesilate may cause interference with the enzymatic value of creatinine (a measure of kidney function), resulting in lower values than expected. If you are going to have any diagnostic tests (including blood tests, urine tests, skin tests that use allergens, etc.), inform your doctor that you are taking this medicine, as it may alter the results.

Using Doxium Fuerte with other medicines

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.

No interactions with other medicines have been described.

Taking Doxium Fuerte with food and drinks

It is recommended to take Doxium Fuerte after meals.

Pregnancy and Breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Pregnancy

Do not take Doxium Fuerte during pregnancy. If you become pregnant or think you may be pregnant, stop taking the medicine and inform your doctor as soon as possible.

Breastfeeding

Do not take Doxium Fuerte during breastfeeding.

Driving and using machines

At the recommended doses, this medicine has not been shown to affect the ability to drive or use machines.

3. How to take Doxium Fuerte

Follow exactly the administration instructions of this medicine as indicated by your doctor. Remember to take your medicine.

Your doctor will indicate the duration of the treatment.

The capsules should be swallowed with water or some other liquid and it is recommended to administer them after meals.

The recommended dose is 3-4 capsules per day (1500-2000 mg), divided into two doses.

If you think the effect of Doxium Fuerte is too strong or too weak, tell your doctor or pharmacist.

If you take more Doxium Fuerte than you should

If you have taken more Doxium Fuerte than you should, consult your doctor or pharmacist immediately.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone: 915 620 420, indicating the medicine and the amount ingested.

If you forget to take Doxium Fuerte

If you forget to take the medicine, you should take the dose as soon as you remember on the same day. If you do not take your capsule one day, take your normal dose the next day. Do not take a double dose to make up for the forgotten doses.

If you have any other questions about the use of this medicine, ask your doctor or pharmacist.

Medicine questions

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4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

The following side effects have been reported frequently:

Gastrointestinal disorders

Abdominal pain, nausea, diarrhea, and vomiting

Nervous system disorders

Headache

Musculoskeletal and connective tissue disorders

Arthralgia, myalgia

Investigations

Increased alanine aminotransferase (increase in a liver enzyme)

The following side effects have been reported infrequently:

General disorders

Fever, chills, asthenia, fatigue

Immune system disorders

Hypersensitivity reactions such as rash, allergic dermatitis, pruritus, urticaria, facial edema

The following side effect has been reported very rarely:

Immune system disorders

Anaphylactic reaction

The following side effects have been reported with an unknown frequency:

Blood disorders

Agranulocytosis, leucopenia, neutropenia

These reactions are generally reversible after discontinuing treatment.

Reporting of side effects

If you experience any side effects, talk to your doctor, pharmacist, or nurse, even if it is possible side effects not listed in this leaflet. You can also report them directly through the Spanish Pharmacovigilance System for Human Use Medicines: https//www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Doxium Fuerte

  • Keep this medicine out of the sight and reach of children.
  • Store below 25°C, in the original package.
  • Do not use this medicine after the expiry date which is stated on the package. The expiry date is the last day of the month stated.

Medicines should not be disposed of via wastewater or household waste. Place the packaging and any unused medicine in the SIGRE collection point at the pharmacy. If you have any further questions, ask your pharmacist how to dispose of the packaging and any unused medicine. This will help protect the environment.

6. Contents of the pack and other information

Composition of Doxium Fuerte

  • The active substance is calcium dobesilate monohydrate. Each hard capsule contains 500 mg of calcium dobesilate monohydrate.
  • The other ingredients are powdered cellulose, magnesium stearate, and silicon dioxide. The capsules contain indigotine, erythrosine, titanium dioxide, water, and gelatin. The ink contains titanium dioxide, povidone, and shellac.

Appearance of the product and contents of the pack

Doxium Fuerte is presented in packs of 60 hard capsules.

The capsules are opaque with a dark blue head and a light blue body, with the name printed on both.

Marketing authorization holder and manufacturer

Marketing authorization holder:

Esteve Pharmaceuticals, S.A.

Passeig de la Zona Franca, 109

08038 Barcelona

Spain

Manufacturer:

TOWA Pharmaceutical Europe, S.L.

c/ de Sant Martí, 75-97

08107 Martorelles (Barcelona)

Spain

This leaflet was approved in: June 2017

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for DOXIUM FUERTE 500 mg HARD CAPSULES

Discuss questions about DOXIUM FUERTE 500 mg HARD CAPSULES, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Svetlana Kolomeeva

Cardiology 18 years exp.

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

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  • Diagnosis and management of hypertension, arrhythmias, and tachycardia.
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  • Respiratory symptoms: colds, flu, sore throat, cough, fever.
  • Digestive issues: heartburn, bloating, constipation, IBS symptoms.
  • Chronic conditions: diabetes, thyroid disorders.
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Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

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Alina Tsurkan

Family medicine 13 years exp.

Dr. Alina Tsurkan is a licensed family medicine physician based in Portugal, offering online consultations for adults and children. She provides professional primary care, with a focus on prevention, accurate diagnosis, and long-term management of acute and chronic conditions.

Dr. Tsurkan supports patients with a wide range of health issues, including:

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Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
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Gastroenterology – Digestive health:
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  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
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Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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Doctor

Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
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  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
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If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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Frequently Asked Questions

Is a prescription required for DOXIUM FUERTE 500 mg HARD CAPSULES?
DOXIUM FUERTE 500 mg HARD CAPSULES requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in DOXIUM FUERTE 500 mg HARD CAPSULES?
The active ingredient in DOXIUM FUERTE 500 mg HARD CAPSULES is calcium dobesilate. This information helps identify medicines with the same composition but different brand names.
How much does DOXIUM FUERTE 500 mg HARD CAPSULES cost in pharmacies?
The average pharmacy price for DOXIUM FUERTE 500 mg HARD CAPSULES is around 6.95 EUR. Prices may vary depending on the manufacturer and dosage form.
Who manufactures DOXIUM FUERTE 500 mg HARD CAPSULES?
DOXIUM FUERTE 500 mg HARD CAPSULES is manufactured by Esteve Pharmaceuticals S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of DOXIUM FUERTE 500 mg HARD CAPSULES online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether DOXIUM FUERTE 500 mg HARD CAPSULES is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to DOXIUM FUERTE 500 mg HARD CAPSULES?
Other medicines with the same active substance (calcium dobesilate) include ETOXISCLEROL 10 mg/mL Injectable Solution, ETOXISCLEROL 20 mg/ml INJECTABLE SOLUTION, ETOXISCLEROL 30 mg/ml INJECTABLE SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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