Bg pattern

DIPRIVAN 10 mg/ml Injectable Emulsion for Infusion

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use DIPRIVAN 10 mg/ml Injectable Emulsion for Infusion

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

Show original

Introduction

Package Leaflet: Information for the User

Diprivan 10 mg/ml injectable emulsion and for infusion

Propofol

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

Keep this leaflet, you may need to read it again.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor, pharmacist, or nurse.
  • If you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack:

  1. What Diprivan is and what it is used for
  2. What you need to know before you use Diprivan
  3. How to use Diprivan
  4. Possible side effects
  5. Storage of Diprivan
  6. Further information

1. What Diprivan is and what it is used for

Diprivan belongs to a group of medicines called “general anesthetics”. General anesthetics are used to produce unconsciousness (sleep) while surgery or other procedures are carried out. It can also be used to sedate you (make you feel drowsy but not completely asleep).

Diprivan 10 mg/ml is used for:

  • induction and maintenance of general anesthesia in adults and children over 1 month of age.
  • sedation of patients over 16 years of age with assisted ventilation in intensive care.
  • sedation of adults and children over 1 month of age during diagnostic and surgical procedures, alone or in combination with local or regional anesthesia.
Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you use Diprivan

Before administering the anesthetic, the anesthesiologist, surgeon, or intensive care physician will assess your clinical condition and any treatment you are currently receiving.

Do not use Diprivan

  • If you are allergic (hypersensitive) to propofol or any of the other components of this medicine (listed in section 6).
  • If you are allergic to soy or peanuts. This is because Diprivan contains soybean oil.
  • In patients 16 years or younger for sedation in intensive care.

Warnings and precautions

Talk to your doctor, pharmacist, or nurse before starting Diprivan if:

  • you have ever had a seizure or convulsion,
  • you have ever been told you have very high levels of fat in your blood or that you have problems absorbing fats. In these cases, your doctor may need to check your blood fat levels,
  • you have any other health problems, such as heart, respiratory, kidney, or liver problems, or if you have been unwell for some time,
  • you are taking any other medicines, including those you have bought without a prescription
  • your body has lost a lot of water (hypovolemia),
  • you have prolonged and/or severe diarrhea,
  • you have ever been told you have a disease called “mitochondrial disease”,
  • you are elderly or debilitated,
  • you have had a head injury along with high pressure in your head.

Before undergoing surgery or any other procedure that requires the administration of any type of anesthesia, it is essential that you inform your doctor if you have a disease called “hereditary predisposition to acute porphyria”.

In rare cases, if propofol is administered for a long time, you may develop a disease called propofol infusion syndrome (PRIS). This disease can damage the heart, muscles, or kidneys, cause other serious problems, and can even lead to death. However, your doctor will closely monitor you and take the necessary measures to prevent this from happening.

Children and adolescents

Diprivan is not recommended for use in newborns.

Other medicines and Diprivan

Tell your doctor, pharmacist, or nurse if you are taking or have recently taken or might take any other medicines.

Tell your doctor before using Diprivan if you are taking any of the following medicines:

  • strong painkillers (opioid analgesics) for intense pain relief
  • medicines called “parasympatholytics” (e.g., medicines used to treat cramps, asthma, Parkinson's disease, and other medicines in this group)
  • benzodiazepines (medicines used to treat anxiety)
  • neostigmine (medicine used to treat a disease called myasthenia gravis)
  • cyclosporin (medicine used to prevent organ rejection in transplants)
  • rifampicin (medicine used to treat tuberculosis)
  • corticosteroids (medicines used to treat asthma, arthritis, immune system diseases, skin diseases, and other diseases)
  • medicines that strengthen the heart, such as digoxin (for the treatment of heart failure)
  • medicines used to treat epilepsy, such as phenytoin, phenobarbital, and others.
  • suxamethonium (muscle relaxant)
  • Midazolam (used to induce sedation [a very relaxed state of calm, drowsiness, or sleep] and to relieve anxiety and muscle tension).

Using Diprivan with food, drinks, and alcohol

You should avoid consuming alcohol at least 8 hours before and after the administration of Diprivan.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor, pharmacist, or nurse before Diprivan is administered to you.

Diprivan should not be administered to pregnant women unless absolutely necessary.

If you are breastfeeding, you should not breastfeed while Diprivan is being administered to you and should discard breast milk for 24 hours after the administration of Diprivan.

Driving and using machines

Diprivan may affect your reaction ability. Your doctor or anesthesiologist will tell you how long you should wait before driving or using machines and will advise you to be accompanied when returning home. Generally, the effects of propofol disappear within 12 hours after the end of its administration.

Diprivan contains soybean oil

Diprivan contains soybean oil. Do not use this medicine if you are allergic to peanuts or soy.

Diprivan contains sodium

This medicine contains less than 1 mmol of sodium (23 mg) per dose; it is essentially “sodium-free”.

3. How to use Diprivan

  • Diprivan will be administered to you by, or under the supervision of, your anesthesiologist or intensive care physician.
  • Diprivan is administered by injection or infusion (drip) into a vein, usually in the back of the hand or in the forearm. A needle or a thin plastic tube called a cannula may be used. For long surgical procedures and in intensive care, an electric pump may be used to control the rate of administration.
  • You may be given a local anesthetic (lidocaine) at the site where Diprivan is injected to reduce the possibility of pain.

The dose of Diprivan will vary depending on your age, body weight, and physical condition. Your doctor will give you the correct dose to initiate and maintain anesthesia or to achieve the required level of sedation, carefully monitoring your responses and vital signs (pulse, blood pressure, breathing, etc.)

It may be necessary to use several medicines to make you sleep or feel drowsy, pain-free, breathing healthily, and maintaining your blood pressure stable. Your anesthesiologist or intensive care physician will decide which medicine to use and when it is necessary and will adjust the dose of Diprivan depending on the medicines used.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

During the induction and maintenance of anesthesia or sedation with Diprivan, the following side effects may occur (while the injection or infusion is being administered or when you are drowsy or asleep). Your doctor will be monitoring for the occurrence of side effects and, if they occur, will administer the appropriate treatment.

Very common: may affect more than 1 in 10 patients

Pain at the injection site (while the injection is being administered, before falling asleep).

Common: may affect up to 1 in 10 patients

  • Headache during the recovery phase.
  • A slower heart rate.
  • Decrease in blood pressure (hypotension).
  • Changes in your breathing pattern during induction.
  • Nausea and vomiting during the recovery phase.

Uncommon: may affect up to 1 in 100 patients

  • Thrombosis and phlebitis.
  • Coughing during the maintenance of anesthesia.

Rare: may affect up to 1 in 1,000 patients

  • Tics and contractions of your body or spasms that can occur during induction, maintenance, and recovery of anesthesia.
  • Coughing during the induction of anesthesia.

Very rare: may affect up to 1 in 10,000 patients

  • Severe allergic reaction, including anaphylactic shock.
  • Unconsciousness after surgery.
  • Fluid accumulation in the lungs.
  • Pancreatitis (inflammation of the pancreas).
  • Discoloration of urine.
  • Sexual excitement.
  • Fever after surgery.
  • Tissue damage (necrosis) at the injection site.

Frequency not known (frequency cannot be estimated from the available data):

  • Metabolic acidosis, increased potassium levels, increased blood fat levels.
  • Euphoria, abuse, and dependence on the medicine.
  • Involuntary movements.
  • Alteration of heart rhythm, loss of heart strength (heart failure), alteration of the nervous signal of your heart detected in the electrocardiogram.
  • Increased liver size.
  • Rhabdomyolysis (breakdown of muscle cells).
  • Breathing difficulties.
  • Prolonged and often painful erection (priapism).
  • Pain and inflammation at the injection site when Diprivan is administered outside the vein.
  • Kidney failure.
  • Hepatitis (liver inflammation), acute liver failure (symptoms may include yellowing of the skin and eyes, itching, dark urine, stomach pain, and liver sensitivity [indicated by pain below the front of the ribcage on the right side], sometimes with loss of appetite).

Reporting of side effects

If you experience any side effects, talk to your doctor, pharmacist, or nurse, even if it is possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es/. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Diprivan

Do not store above 25°C. Do not freeze.

Keep out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiry date is the last day of the month shown.

After dilution: Use within 6 hours.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help protect the environment.

6. Further information

Composition of Diprivan 10 mg/ml

  • The active substance is propofol.
  • The other ingredients are refined soybean oil, purified egg phosphatide, glycerol, sodium hydroxide, nitrogen, water for injection, and disodium edetate.

Appearance and packaging

This medicine is presented in boxes of 5 ampoules with 20 ml of emulsion.

Marketing authorization holder and manufacturer

Marketing authorization holder:

Aspen Pharma Trading Limited

3016 Lake Drive,

Citywest Business Campus,

Dublin 24, Ireland

Tel: +34 952 010 137

Manufacturer:

Corden Pharma S.P.A.

Caponago

Milan (Italy)

Local representative:

ASPEN PHARMACARE ESPAÑA, S.L.

Avenida Diagonal, 512,

Planta Interior 1, Oficina 4,

Barcelona, 08006, Spain

Date of last revision of this leaflet: 08/2024

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for DIPRIVAN 10 mg/ml Injectable Emulsion for Infusion

Discuss questions about DIPRIVAN 10 mg/ml Injectable Emulsion for Infusion, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (29)
Doctor

Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
Camera Book a video appointment
€60
5.0 (29)
Doctor

Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

Camera Book a video appointment
€60
5.0 (5)
Doctor

Anastasiia Hladkykh

Psychiatry 15 years exp.

Dr Anastasiia Hladkykh is a physician-psychotherapist and psychologist with over 14 years of experience working with individuals struggling with various types of addictions and their families. She provides online consultations for adults, combining medical knowledge with deep psychological support and practical tools.

Key areas of expertise:

  • Addiction treatment: alcohol and drug dependence, gambling addiction, compulsive behaviours, codependent relationships.
  • Support for families of addicted individuals, behavioural correction within the family system, guidance for maintaining remission.
  • Mental health: depression, bipolar disorder, obsessive-compulsive disorder (OCD), anxiety disorders, phobias, PTSD, generalised anxiety, emotional trauma, and the psychological impact of loss or emigration.
  • Psychoeducation: explaining complex mental health concepts in simple language, helping patients and their families understand diagnoses and treatment steps.
Therapeutic approach:
  • Client-centred, straightforward, and empathetic – focused on practical outcomes and emotional stabilisation.
  • Prescribes medications when needed, but always aims to minimise unnecessary pharmaceutical use.
  • Certified in multiple evidence-based methods: CBT, NLP (Master Practitioner), Ericksonian hypnosis, symbol drama, art therapy, and systemic therapy.
  • Each consultation results in a clear, structured plan – patients leave knowing exactly what to do next.
Experience and background:
  • Member of the German association Gesundheitpraktikerin and the NGO “Mit dem Sonne in jedem Herzen.”
  • More than 18 publications in international peer-reviewed journals, translated into several languages.
  • Volunteer work with Ukrainian refugees and military personnel at the University Clinic of Regensburg.
Camera Book a video appointment
€130
5.0 (2)
Doctor

Svetlana Kolomeeva

Cardiology 18 years exp.

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

  • High blood pressure, headaches, dizziness, swelling, palpitations.
  • Diagnosis and management of hypertension, arrhythmias, and tachycardia.
  • Metabolic syndrome, excess weight, high cholesterol.
  • Chronic fatigue, insomnia, poor concentration, anxiety.
  • Respiratory symptoms: colds, flu, sore throat, cough, fever.
  • Digestive issues: heartburn, bloating, constipation, IBS symptoms.
  • Chronic conditions: diabetes, thyroid disorders.
  • Interpretation of lab tests and medical reports, therapy adjustment.
  • Second opinion and decision-making support.
  • Cardiovascular disease prevention and metabolic risk reduction.
  • Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

Camera Book a video appointment
€55
0.0 (0)
Doctor

Maria Martelli

Pain medicine 12 years exp.

Dr Maria Martelli is a medical doctor specialising in anaesthesiology and pain medicine. She provides online consultations for adults, focusing on the assessment and management of acute, chronic, and complex pain conditions, as well as supportive care in serious illness.

She graduated from the Medical University of Silesia in Katowice and completed her specialisation in Anaesthesiology and Intensive Care. Alongside hospital work, she has extensive experience in home and inpatient hospice care, supporting patients with severe pain and advanced disease. Since 2021, she has been a certified specialist and continues to work in anaesthesiology, intensive care, and pain treatment.

Patients consult her for:

  • Chronic pain lasting more than 3 months (musculoskeletal, neuropathic, mixed pain).
  • Acute pain requiring medical assessment and treatment planning.
  • Post-operative pain and recovery support.
  • Cancer-related pain and symptom relief.
  • Palliative care support and quality-of-life improvement.
  • Adjustment and optimisation of pain medication.
  • Second opinions for complex or treatment-resistant pain.
Dr Martelli takes a structured, evidence-based approach, carefully analysing symptoms, previous treatments, and overall health status. Her consultations focus on realistic pain control goals, safety of therapy, and improving daily functioning.

She is especially attentive to patients living with long-term pain or serious illness, providing clear explanations, compassionate guidance, and medically sound recommendations adapted to each individual situation.

Camera Book a video appointment
€99
0.0 (1)
Doctor

Daria Portnova

Psychiatry 31 years exp.

Dr Daria Portnova is a psychiatrist and psychotherapist with over 30 years of clinical experience. She works with adults and adolescents aged 14 and over, providing online psychiatric and psychotherapeutic consultations.

In her practice, Dr Portnova supports patients facing the onset of mental health conditions, chronic psychiatric disorders, psychotic symptoms, trauma-related states, and complex emotional crises. Her work is structured and safety-focused, with an emphasis on stabilisation, accurate diagnosis, and long-term improvement in quality of life.

Patients consult Dr Daria Portnova for the following concerns:

  • existential crises and complex life situations;
  • loss, grief, and emotional exhaustion;
  • relationship difficulties, separation, and divorce;
  • psychological and psychiatric trauma, including complex PTSD (cPTSD);
  • anxiety disorders: generalised anxiety disorder and panic disorder;
  • social anxiety and social phobia;
  • obsessive-compulsive disorder (OCD);
  • sleep disorders;
  • depressive disorders;
  • bipolar affective disorder;
  • schizoaffective disorder;
  • schizophrenia;
  • personality disorders.
Dr Portnova combines psychiatric assessment with a psychotherapeutic approach. She works with evidence-based methods, including cognitive behavioural therapy (CBT) and third-wave approaches such as ACT, FACT, and CFT. Consultations are focused on clear clinical understanding, practical recommendations, and ongoing support over time.
Camera Book a video appointment
€110
5.0 (77)
Doctor

Sergey Ilyasov

Psychiatry 7 years exp.

Dr Sergey Ilyasov is an experienced neurologist and qualified psychiatrist who provides online consultations for adults and adolescents. Combining deep neurological expertise with a modern psychiatric approach, he ensures comprehensive diagnostics and effective treatment for a wide range of conditions affecting both physical and mental health.

Dr. Ilyasov helps patients in the following cases:

  • Chronic headaches (migraine, tension-type headache), back pain, neuropathic pain, dizziness, numbness in limbs, coordination disorders.
  • Anxiety disorders (panic attacks, generalized anxiety disorder), depression (including atypical and treatment-resistant forms), sleep disturbances (insomnia, hypersomnia, nightmares), stress, burnout.
  • Chronic pain syndromes and psychosomatic symptoms (e.g., irritable bowel syndrome related to stress, vegetative-vascular dystonia).
  • Behavioral disorders and concentration difficulties in adolescents (including ADHD, autism spectrum disorders), nervous tics.
  • Memory impairments, phobias, obsessive-compulsive disorder (OCD), emotional swings, and support for post-traumatic stress disorder (PTSD).

Thanks to his dual specialization in neurology and psychiatry, Dr Sergey Ilyasov offers integrated and evidence-based care for complex conditions requiring a multidisciplinary approach. His consultations focus on accurate diagnosis, development of an individualized treatment plan (including pharmacotherapy and psychotherapeutic methods), and long-term support adapted to each patient's unique needs.

Book an online consultation with Dr. Sergey Ilyasov to receive qualified assistance and improve your well-being today.

Camera Book a video appointment
€89

Frequently Asked Questions

Is a prescription required for DIPRIVAN 10 mg/ml Injectable Emulsion for Infusion?
DIPRIVAN 10 mg/ml Injectable Emulsion for Infusion requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in DIPRIVAN 10 mg/ml Injectable Emulsion for Infusion?
The active ingredient in DIPRIVAN 10 mg/ml Injectable Emulsion for Infusion is propofol. This information helps identify medicines with the same composition but different brand names.
Who manufactures DIPRIVAN 10 mg/ml Injectable Emulsion for Infusion?
DIPRIVAN 10 mg/ml Injectable Emulsion for Infusion is manufactured by Aspen Pharma Trading Limited. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of DIPRIVAN 10 mg/ml Injectable Emulsion for Infusion online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether DIPRIVAN 10 mg/ml Injectable Emulsion for Infusion is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to DIPRIVAN 10 mg/ml Injectable Emulsion for Infusion?
Other medicines with the same active substance (propofol) include DIPRIVAN 20 mg/ml EMULSION FOR INFUSION, PROPOFOL BAXTER 10mg/ml Injectable Emulsion for Infusion, PROPOFOL BAXTER 20mg/ml Injectable Emulsion for Infusion. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
bg-pattern-dark

Stay informed about Oladoctor

News about new services, product updates and useful information for patients.

Follow us on social media