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DIARFIN 2 mg HARD CAPSULES

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About the medicine

How to use DIARFIN 2 mg HARD CAPSULES

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Diarfin 2 mg Hard Capsules

loperamide hydrochloride

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

Follow exactly the administration instructions of the medicine contained in this leaflet or as indicated by your doctor or pharmacist.

  • Keep this leaflet, as you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience side effects, consult your doctor or pharmacist, even if it is a side effect not listed in this leaflet. See section 4.
  • You should consult a doctor if it worsens or does not improve after 2 days of treatment.

Contents of the Package Leaflet

  1. What is Diarfin and what is it used for
  2. What you need to know before taking Diarfin
  3. How to take Diarfin
  4. Possible side effects
  5. Storage of Diarfin
  6. Contents of the pack and further information

1. What is Diarfin and what is it used for

Diarfin is an antidiarrheal that reduces intestinal movements and secretions, resulting in a decrease in liquid stools.

Diarfin is used for the symptomatic treatment of acute non-specific diarrhea in adults and children over 12 years of age.

You should consult a doctor if it worsens or does not improve after 2 days.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before taking Diarfin

Do not take Diarfin

  • If you are allergic to loperamide hydrochloride or any of the other components of this medicine (listed in section 6).
  • Do not administer to children under 2 years of age.
  • If blood appears in the stool or high fever (above 38 °C).
  • If you have been diagnosed with acute ulcerative colitis (inflammation of the intestine).
  • If you suffer from severe diarrhea (pseudomembranous colitis) after taking antibiotics.
  • If you suffer from diarrhea due to an infection caused by organisms such as Salmonella, Shigellaor Campylobacter.

Warnings and precautions

Consult your doctor or pharmacist before starting to take Diarfin.

  • If there is no improvement within 48 hours or if fever, constipation, or other symptoms such as abdominal swelling or paralytic ileus (absence of intestinal movements) appear, discontinue treatment and consult your doctor.
  • If you suffer from severe diarrhea, your body loses more fluids, sugars, and salts than usual, so you will need to replenish fluids by drinking more than usual. Dehydration is characterized by dry mouth, excessive thirst, decreased urine output, wrinkled skin, dizziness, and drowsiness. It is very important to prevent dehydration in children and elderly patients.
  • Patient with AIDS should discontinue treatment when the first symptoms of abdominal swelling appear.
  • If you have any liver or kidney disease or blood disorders, consult your doctor before taking this medicine.
  • Since the treatment of diarrhea with Diarfin is only symptomatic, diarrhea should be treated from its cause, when possible.
  • Do not take this medicine for a use other than indicated (see section 1) and never take more than the recommended amount (see section 3). Serious heart problems (whose symptoms include rapid or irregular heartbeats) have been reported in patients who have taken an excessive amount of loperamide, the active ingredient of Diarfin.

Children and adolescents

This medicine should not be administered to children under 12 years of age without consulting a doctor.

Other medicines and Diarfin

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicine.

In particular, inform your doctor or pharmacist if you are taking any of the following medicines:

  • Ritonavir, saquinavir (used to treat HIV).
  • Quinidine (used to treat heart rhythm disorders).
  • Desmopressin (used to treat central diabetes insipidus and nocturnal urinary incontinence in children).
  • Itraconazole or ketoconazole (used to treat fungal infections).
  • Gemfibrozil (used to reduce cholesterol).
  • St. John's Wort (used to improve mood and treat mild depression).
  • Valerian (used to treat mild nervousness and anxiety).
  • Opioid analgesics (used to treat intense pain) as it may increase the risk of severe constipation and central nervous system depression (e.g., drowsiness or decreased consciousness).
  • Broad-spectrum antibiotics as it may worsen antibiotic-associated diarrhea.

Diarfin may enhance the effect of similar medicines.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Pregnancy

The safety of this medicine during pregnancy has not been established, so pregnant women should not take this medicine unless prescribed by a doctor.

Breastfeeding

Women who are breastfeeding should not use this medicine without consulting their doctor, as small amounts of it may pass into breast milk.

Driving and using machines

Drowsiness, dizziness, or drowsiness may occur during treatment with Diarfin, so it is advised not to use machinery or drive vehicles.

Diarfin contains lactose.If your doctor has told you that you have an intolerance to some sugars, consult with him before taking this medicine.

Diarfin contains the colorant Orange Yellow S (E-110).This medicine may cause allergic reactions because it contains Orange Yellow S (E-110). It can cause asthma, especially in patients allergic to acetylsalicylic acid.

3. How to take Diarfin

Follow exactly the administration instructions of the medicine contained in this leaflet or as indicated by your doctor or pharmacist. In case of doubt, ask your doctor or pharmacist.

The recommended dose is:

Adults

2 capsules (4 mg of loperamide hydrochloride) as an initial dose, followed by 1 capsule (2 mg of loperamide hydrochloride) after each diarrheal stool.

The maximum dose for adults is 8 capsules (16 mg of loperamide hydrochloride) per day.

Children over 12 years of age

1 capsule (2 mg of loperamide hydrochloride) as an initial dose, followed by 1 capsule (2 mg of loperamide hydrochloride) after each diarrheal stool.

In children, the maximum daily dose should be related to body weight:

Child's weight

Maximum number of capsules per day

From 27 kg

Maximum 4 capsules

From 34 kg

Maximum 5 capsules

From 40 kg

Maximum 6 capsules

From 47 kg

Maximum 7 capsules

Patient with liver disease

They should consult their doctor before taking this medicine.

Method of administration

This medicine is taken orally. Swallow the capsules with a glass of water.

Do not exceed the recommended dose.

If you think the effect of Diarfin is too strong or too weak, tell your doctor or pharmacist.

If you take more Diarfin than you should

If you have taken too much Diarfin, contact a doctor or hospital as soon as possible for advice. The symptoms may include: increased heart rate, irregular heartbeats, cardiac arrhythmias (these symptoms can have potentially serious and life-threatening consequences), muscle stiffness, uncoordinated movements, drowsiness, difficulty urinating, or weak breathing.

Children react more severely to high amounts of Diarfin than adults. If a child takes an excessive amount or presents any of the above symptoms, call a doctor immediately.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone (91) 562 04 20, indicating the medicine and the amount taken.

If you forget to take Diarfin

Do not take a double dose to make up for the forgotten dose.

If you have any other doubts about the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

If any of the following side effects occur, discontinue treatment and consult your doctor:

  • Allergic reactions such as skin rash, swelling of the face, tongue, or throat that can cause difficulty swallowing or breathing (angioedema).
  • Severe allergic reactions including anaphylactic shock.
  • Severe abdominal pain.
  • Blisters or significant skin peeling.
  • Loss or decrease in level of consciousness.

Other side effects that may occur are:

Common side effects (may affect up to 1 in 10 people):

  • Headache (cephalalgia).
  • Dizziness.
  • Constipation.
  • Nausea.
  • Gas (flatulence).

Uncommon side effects (may affect up to 1 in 100 people):

  • Vomiting.
  • Pain or discomfort in the upper-middle part of the stomach (dyspepsia).
  • Dry mouth.
  • Abdominal pain or discomfort.
  • Skin discoloration (exanthema).
  • Drowsiness.

Rare side effects (may affect up to 1 in 1,000 people):

  • Intestinal paralysis (absence of intestinal movements or paralytic ileus).
  • Abdominal swelling (distension).
  • Dilation of the large intestine (megacolon).
  • Loss or decrease in level of consciousness.
  • Stupor (general unconsciousness).
  • Muscle hypertonia.
  • Abnormal coordination.
  • Blisters on the skin (bullous eruptions, including Stevens-Johnson syndrome, erythema multiforme, and toxic epidermal necrolysis).
  • Skin disorder that produces lesions and intense itching (urticaria).
  • Decreased urine output (urinary retention).
  • Fatigue.
  • Pupillary constriction (miosis).
  • Itching (pruritus).

Side effects of unknown frequency (cannot be estimated from the available data):

Upper abdominal pain, abdominal pain radiating to the back, abdominal tenderness, fever, rapid pulse, nausea, vomiting, which may be symptoms of pancreatitis (acute pancreatitis).

Reporting of side effects

If you experience any side effects, consult your doctor or pharmacist, even if it is a possible side effect not listed in this leaflet. You can also report them directly through the Spanish Medicines and Health Products Agency (AEMPS) https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Diarfin

Keep this medicine out of the sight and reach of children.

This medicine does not require special storage conditions.

Do not use this medicine after the expiration date that appears on the packaging after CAD. The expiration date is the last day of the month indicated.

Medicines should not be disposed of via wastewater or household waste. Dispose of the packaging and any unused medicine in the pharmacy's SIGRE collection point. If in doubt, ask your pharmacist how to dispose of the packaging and any unused medicine. This will help protect the environment.

6. Contents of the pack and further information

Composition of Diarfin

  • The active ingredient of Diarfin is loperamide hydrochloride. Each capsule contains 2 mg of loperamide hydrochloride.
  • The other ingredients are:

Capsule content:pregelatinized corn starch, lactose monohydrate, anhydrous colloidal silica, and magnesium stearate.

Hard capsule:gelatin, orange yellow S (E-110), and titanium dioxide (E-171).

Appearance of the product and pack contents

Diarfin is presented in the form of hard gelatin capsules with an orange cap and orange body.

It is presented in PVC-PVDC/ALU blisters. Each pack of Diarfin contains 10 or 20 capsules.

Marketing authorization holder and manufacturer

Laboratorios Cinfa, S.A.

Carretera Olaz-Chipi, 10. Polígono Industrial Areta

31620 Huarte (Navarra) – Spain

Date of the last revision of this leaflet:July 2022

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for DIARFIN 2 mg HARD CAPSULES

Discuss questions about DIARFIN 2 mg HARD CAPSULES, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
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  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
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  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
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Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
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  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
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Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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Bulat Garipov

General medicine 15 years exp.

Dr. Bulat Garipov is a radiologist with more than 15 years of experience, specializing in magnetic resonance imaging (MRI). Throughout his professional career, he has worked in leading diagnostic imaging centers, both in on-site practice and teleradiology, which has allowed him to develop a broad and versatile approach to radiology.

Over the years, he has gained solid experience in interpreting MRI studies in various areas, including:

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Additionally, Dr. Garipov is open to new collaboration opportunities in radiology and teleradiology projects. He offers his expertise in MRI, providing both first and second readings of studies, as well as advanced image interpretation, ensuring accurate and high-quality diagnostics.

You could consult Dr. Bulat Garipov in cases where accurate interpretation of MRI studies or a second expert opinion is required. His expertise is especially valuable in cases of suspected neurological conditions, back and joint pain, vascular disorders, as well as in the diagnosis of abdominal and pelvic diseases. The doctor also provides support in complex or unclear clinical situations, including the review of previously performed studies, which helps improve diagnostic accuracy and determine the optimal treatment strategy. A teleradiology format is available, allowing you to receive a professional opinion remotely.

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Doctor

Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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Doctor

Alexander Nazarchuk

Allergology 7 years exp.

Dr. Alexander Nazarchuk is a physician specialising in allergology and internal medicine. He provides online consultations for adults, following the principles of evidence-based medicine — no outdated treatments or unnecessary tests, with clear explanations and a personalised approach. He helps patients with a wide range of allergic and therapeutic conditions, from common day-to-day complaints to complex cases involving allergies, gastrointestinal issues, cardiovascular concerns, respiratory symptoms, and more.

You can consult Dr. Nazarchuk for:

  • Test interpretation and guidance on diagnostic plans.
  • Allergic rhinitis, hay fever, bronchial asthma (including severe cases).
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  • Atopic dermatitis, urticaria, contact allergies.
  • Allergen-specific immunotherapy (AIT) – initiation and ongoing management.
  • Abdominal pain, bloating, changes in bowel habits, nausea, heartburn.
  • High blood pressure and adjustment of baseline antihypertensive therapy.
  • Hyperlipidaemia and elevated cholesterol.
  • Cough, nasal congestion, fever, sore throat.
  • Anaemia, including iron deficiency and related conditions.
  • Other issues related to allergology and internal medicine.

During consultations, Dr. Nazarchuk takes a thorough, structured approach — analysing symptoms, identifying potential causes, and helping patients make informed decisions. Whether treatment, further investigation, or monitoring is needed, he explains each step clearly so you understand your health and how best to manage it.

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Doctor

Sviatoslav Chekhun

Oncology 13 years exp.

Dr. Sviatoslav Chekhun is a medical oncologist with international clinical and research experience, specializing in modern medical oncology and a personalized approach to cancer treatment.

Currently (since 2025), he works as a Medical Oncologist at Institut Català d’Oncologia (Girona, Spain). Previously, he completed his residency in Medical Oncology and was involved in clinical research at Hospital Universitari Germans Trias i Pujol.

Dr. Chekhun has a strong academic and scientific background. He served as a lecturer in Internal Medicine at O.O. Bohomolets National Medical University and conducted research in experimental oncology at the R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology.

Earlier in his career, he worked as a medical oncologist at the Kyiv City Clinical Oncological Center and contributed to regulatory evaluation of medicinal products at the State Expert Center of the Ministry of Health of Ukraine.

When to consult Dr. Chekhun:

  •  for diagnosis or clarification of a cancer diagnosis
  •  to obtain a second opinion on an existing treatment plan 
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  •  in case of doubts about treatment strategy or disease progression 

Consultation format

Dr. Chekhun provides online consultations, where you can receive:

  •  expert second opinion 
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Important:
Prescription and monitoring of medications must be carried out by your treating physician in an in-person (offline) setting. An online consultation does not replace a face-to-face visit but helps you make more informed decisions about your treatment.

Dr. Sviatoslav Chekhun combines clinical practice, research, and international experience, enabling him to provide patients with modern, evidence-based approaches in oncology.

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€280

Frequently Asked Questions

Is a prescription required for DIARFIN 2 mg HARD CAPSULES?
DIARFIN 2 mg HARD CAPSULES does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in DIARFIN 2 mg HARD CAPSULES?
The active ingredient in DIARFIN 2 mg HARD CAPSULES is loperamide. This information helps identify medicines with the same composition but different brand names.
Who manufactures DIARFIN 2 mg HARD CAPSULES?
DIARFIN 2 mg HARD CAPSULES is manufactured by Laboratorios Cinfa S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of DIARFIN 2 mg HARD CAPSULES online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether DIARFIN 2 mg HARD CAPSULES is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to DIARFIN 2 mg HARD CAPSULES?
Other medicines with the same active substance (loperamide) include ABECLIN 2 mg TABLETS, DIARFIN FLAS 2 mg ORAL LYOPHILIZED, ELISSAN 2 mg TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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