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DIARFIN 2 mg HARD CAPSULES

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About the medicine

How to use DIARFIN 2 mg HARD CAPSULES

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Diarfin 2 mg Hard Capsules

loperamide hydrochloride

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

Follow exactly the administration instructions of the medicine contained in this leaflet or as indicated by your doctor or pharmacist.

  • Keep this leaflet, as you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience side effects, consult your doctor or pharmacist, even if it is a side effect not listed in this leaflet. See section 4.
  • You should consult a doctor if it worsens or does not improve after 2 days of treatment.

Contents of the Package Leaflet

  1. What is Diarfin and what is it used for
  2. What you need to know before taking Diarfin
  3. How to take Diarfin
  4. Possible side effects
  5. Storage of Diarfin
  6. Contents of the pack and further information

1. What is Diarfin and what is it used for

Diarfin is an antidiarrheal that reduces intestinal movements and secretions, resulting in a decrease in liquid stools.

Diarfin is used for the symptomatic treatment of acute non-specific diarrhea in adults and children over 12 years of age.

You should consult a doctor if it worsens or does not improve after 2 days.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before taking Diarfin

Do not take Diarfin

  • If you are allergic to loperamide hydrochloride or any of the other components of this medicine (listed in section 6).
  • Do not administer to children under 2 years of age.
  • If blood appears in the stool or high fever (above 38 °C).
  • If you have been diagnosed with acute ulcerative colitis (inflammation of the intestine).
  • If you suffer from severe diarrhea (pseudomembranous colitis) after taking antibiotics.
  • If you suffer from diarrhea due to an infection caused by organisms such as Salmonella, Shigellaor Campylobacter.

Warnings and precautions

Consult your doctor or pharmacist before starting to take Diarfin.

  • If there is no improvement within 48 hours or if fever, constipation, or other symptoms such as abdominal swelling or paralytic ileus (absence of intestinal movements) appear, discontinue treatment and consult your doctor.
  • If you suffer from severe diarrhea, your body loses more fluids, sugars, and salts than usual, so you will need to replenish fluids by drinking more than usual. Dehydration is characterized by dry mouth, excessive thirst, decreased urine output, wrinkled skin, dizziness, and drowsiness. It is very important to prevent dehydration in children and elderly patients.
  • Patient with AIDS should discontinue treatment when the first symptoms of abdominal swelling appear.
  • If you have any liver or kidney disease or blood disorders, consult your doctor before taking this medicine.
  • Since the treatment of diarrhea with Diarfin is only symptomatic, diarrhea should be treated from its cause, when possible.
  • Do not take this medicine for a use other than indicated (see section 1) and never take more than the recommended amount (see section 3). Serious heart problems (whose symptoms include rapid or irregular heartbeats) have been reported in patients who have taken an excessive amount of loperamide, the active ingredient of Diarfin.

Children and adolescents

This medicine should not be administered to children under 12 years of age without consulting a doctor.

Other medicines and Diarfin

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicine.

In particular, inform your doctor or pharmacist if you are taking any of the following medicines:

  • Ritonavir, saquinavir (used to treat HIV).
  • Quinidine (used to treat heart rhythm disorders).
  • Desmopressin (used to treat central diabetes insipidus and nocturnal urinary incontinence in children).
  • Itraconazole or ketoconazole (used to treat fungal infections).
  • Gemfibrozil (used to reduce cholesterol).
  • St. John's Wort (used to improve mood and treat mild depression).
  • Valerian (used to treat mild nervousness and anxiety).
  • Opioid analgesics (used to treat intense pain) as it may increase the risk of severe constipation and central nervous system depression (e.g., drowsiness or decreased consciousness).
  • Broad-spectrum antibiotics as it may worsen antibiotic-associated diarrhea.

Diarfin may enhance the effect of similar medicines.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Pregnancy

The safety of this medicine during pregnancy has not been established, so pregnant women should not take this medicine unless prescribed by a doctor.

Breastfeeding

Women who are breastfeeding should not use this medicine without consulting their doctor, as small amounts of it may pass into breast milk.

Driving and using machines

Drowsiness, dizziness, or drowsiness may occur during treatment with Diarfin, so it is advised not to use machinery or drive vehicles.

Diarfin contains lactose.If your doctor has told you that you have an intolerance to some sugars, consult with him before taking this medicine.

Diarfin contains the colorant Orange Yellow S (E-110).This medicine may cause allergic reactions because it contains Orange Yellow S (E-110). It can cause asthma, especially in patients allergic to acetylsalicylic acid.

3. How to take Diarfin

Follow exactly the administration instructions of the medicine contained in this leaflet or as indicated by your doctor or pharmacist. In case of doubt, ask your doctor or pharmacist.

The recommended dose is:

Adults

2 capsules (4 mg of loperamide hydrochloride) as an initial dose, followed by 1 capsule (2 mg of loperamide hydrochloride) after each diarrheal stool.

The maximum dose for adults is 8 capsules (16 mg of loperamide hydrochloride) per day.

Children over 12 years of age

1 capsule (2 mg of loperamide hydrochloride) as an initial dose, followed by 1 capsule (2 mg of loperamide hydrochloride) after each diarrheal stool.

In children, the maximum daily dose should be related to body weight:

Child's weight

Maximum number of capsules per day

From 27 kg

Maximum 4 capsules

From 34 kg

Maximum 5 capsules

From 40 kg

Maximum 6 capsules

From 47 kg

Maximum 7 capsules

Patient with liver disease

They should consult their doctor before taking this medicine.

Method of administration

This medicine is taken orally. Swallow the capsules with a glass of water.

Do not exceed the recommended dose.

If you think the effect of Diarfin is too strong or too weak, tell your doctor or pharmacist.

If you take more Diarfin than you should

If you have taken too much Diarfin, contact a doctor or hospital as soon as possible for advice. The symptoms may include: increased heart rate, irregular heartbeats, cardiac arrhythmias (these symptoms can have potentially serious and life-threatening consequences), muscle stiffness, uncoordinated movements, drowsiness, difficulty urinating, or weak breathing.

Children react more severely to high amounts of Diarfin than adults. If a child takes an excessive amount or presents any of the above symptoms, call a doctor immediately.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone (91) 562 04 20, indicating the medicine and the amount taken.

If you forget to take Diarfin

Do not take a double dose to make up for the forgotten dose.

If you have any other doubts about the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

If any of the following side effects occur, discontinue treatment and consult your doctor:

  • Allergic reactions such as skin rash, swelling of the face, tongue, or throat that can cause difficulty swallowing or breathing (angioedema).
  • Severe allergic reactions including anaphylactic shock.
  • Severe abdominal pain.
  • Blisters or significant skin peeling.
  • Loss or decrease in level of consciousness.

Other side effects that may occur are:

Common side effects (may affect up to 1 in 10 people):

  • Headache (cephalalgia).
  • Dizziness.
  • Constipation.
  • Nausea.
  • Gas (flatulence).

Uncommon side effects (may affect up to 1 in 100 people):

  • Vomiting.
  • Pain or discomfort in the upper-middle part of the stomach (dyspepsia).
  • Dry mouth.
  • Abdominal pain or discomfort.
  • Skin discoloration (exanthema).
  • Drowsiness.

Rare side effects (may affect up to 1 in 1,000 people):

  • Intestinal paralysis (absence of intestinal movements or paralytic ileus).
  • Abdominal swelling (distension).
  • Dilation of the large intestine (megacolon).
  • Loss or decrease in level of consciousness.
  • Stupor (general unconsciousness).
  • Muscle hypertonia.
  • Abnormal coordination.
  • Blisters on the skin (bullous eruptions, including Stevens-Johnson syndrome, erythema multiforme, and toxic epidermal necrolysis).
  • Skin disorder that produces lesions and intense itching (urticaria).
  • Decreased urine output (urinary retention).
  • Fatigue.
  • Pupillary constriction (miosis).
  • Itching (pruritus).

Side effects of unknown frequency (cannot be estimated from the available data):

Upper abdominal pain, abdominal pain radiating to the back, abdominal tenderness, fever, rapid pulse, nausea, vomiting, which may be symptoms of pancreatitis (acute pancreatitis).

Reporting of side effects

If you experience any side effects, consult your doctor or pharmacist, even if it is a possible side effect not listed in this leaflet. You can also report them directly through the Spanish Medicines and Health Products Agency (AEMPS) https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Diarfin

Keep this medicine out of the sight and reach of children.

This medicine does not require special storage conditions.

Do not use this medicine after the expiration date that appears on the packaging after CAD. The expiration date is the last day of the month indicated.

Medicines should not be disposed of via wastewater or household waste. Dispose of the packaging and any unused medicine in the pharmacy's SIGRE collection point. If in doubt, ask your pharmacist how to dispose of the packaging and any unused medicine. This will help protect the environment.

6. Contents of the pack and further information

Composition of Diarfin

  • The active ingredient of Diarfin is loperamide hydrochloride. Each capsule contains 2 mg of loperamide hydrochloride.
  • The other ingredients are:

Capsule content:pregelatinized corn starch, lactose monohydrate, anhydrous colloidal silica, and magnesium stearate.

Hard capsule:gelatin, orange yellow S (E-110), and titanium dioxide (E-171).

Appearance of the product and pack contents

Diarfin is presented in the form of hard gelatin capsules with an orange cap and orange body.

It is presented in PVC-PVDC/ALU blisters. Each pack of Diarfin contains 10 or 20 capsules.

Marketing authorization holder and manufacturer

Laboratorios Cinfa, S.A.

Carretera Olaz-Chipi, 10. Polígono Industrial Areta

31620 Huarte (Navarra) – Spain

Date of the last revision of this leaflet:July 2022

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for DIARFIN 2 mg HARD CAPSULES

Discuss questions about DIARFIN 2 mg HARD CAPSULES, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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€58
5.0 (5)
Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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€80
5.0 (1055)
Doctor

Andrei Popov

General medicine 7 years exp.

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

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€80
5.0 (183)
Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Camera Book a video appointment
€50

Frequently Asked Questions

Is a prescription required for DIARFIN 2 mg HARD CAPSULES?
DIARFIN 2 mg HARD CAPSULES does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in DIARFIN 2 mg HARD CAPSULES?
The active ingredient in DIARFIN 2 mg HARD CAPSULES is loperamide. This information helps identify medicines with the same composition but different brand names.
Who manufactures DIARFIN 2 mg HARD CAPSULES?
DIARFIN 2 mg HARD CAPSULES is manufactured by Laboratorios Cinfa S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of DIARFIN 2 mg HARD CAPSULES online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether DIARFIN 2 mg HARD CAPSULES is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to DIARFIN 2 mg HARD CAPSULES?
Other medicines with the same active substance (loperamide) include ABECLIN 2 mg TABLETS, DIARFIN FLAS 2 mg ORAL LYOPHILIZED, ELISSAN 2 mg TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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