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ASPIRINA 500 mg Granules Oral Solution/Suspension

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About the medicine

How to use ASPIRIN 500 mg GRANULES

Contents of the leaflet

  1. Introduction
  2. What is Aspirin and what is it used for
  3. What you need to know before taking Aspirin
  4. How to take Aspirin
  5. Possible side effects
  6. Storage of Aspirin
  7. Contents of the pack and further information

Introduction

Package Leaflet: Information for the User

Aspirin 500 mg Granules

Acetylsalicylic Acid

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

Follow exactly the administration instructions of the medicine contained in this leaflet or as indicated by your doctor or pharmacist.

  • Keep this leaflet, you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience side effects, consult your doctor or pharmacist, even if they are not listed in this leaflet. See section 4.
  • You should consult a doctor if your symptoms worsen or do not improve after 5 days for pain or 3 days for fever.

Contents of the Package Leaflet

  1. What is Aspirin and what is it used for
  2. What you need to know before taking Aspirin
  3. How to take Aspirin
  4. Possible side effects
  5. Storage of Aspirin
  1. Contents of the pack and further information

1. What is Aspirin and what is it used for

The active ingredient of this medicine, acetylsalicylic acid, belongs to a group of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs). It relieves pain and reduces fever.

This medicine is used for the symptomatic relief of occasional mild or moderate pain, such as headache, dental, menstrual, muscular (cramps) or back (lumbago) pain and febrile conditions in adults and adolescents over 16 years of age.

You should consult a doctor if your symptoms worsen or do not improve after 5 days for pain or 3 days for fever.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before taking Aspirin

Do not take Aspirin if

  • you are allergic or have had an allergic reaction to acetylsalicylic acid or any other component of this medicine (listed in section 6),
  • you have stomach or intestinal ulcers, or recurring gastric discomfort,
  • you have had allergic reactions of an asthmatic type (difficulty breathing, shortness of breath, bronchospasm, and in some cases cough or wheezing),
  • you have asthma,
  • you have nasal polyps associated with asthma that are produced or increased by acetylsalicylic acid,
  • you have hemophilia or other blood coagulation problems,
  • you are being treated with oral anticoagulant medications,
  • you have kidney and/or liver disease (renal and/or hepatic insufficiency),
  • you are under 16 years of age, as the use of acetylsalicylic acid has been linked to Reye's Syndrome, a rare but serious disease,
  • you are in your third trimester of pregnancy.

Be careful with Aspirin

You should consult your doctor if you need this medicine:

  • if you have high blood pressure, or have reduced kidney, heart, or liver function, or have blood coagulation disorders,
  • if you have had stomach or intestinal ulcers,
  • if you are being treated with anticoagulants, you should consult your doctor before taking this medicine,
  • if you are taking anti-inflammatory medications or other types of medications, as certain medications can interact with Aspirin 500 mg granules and produce undesirable effects (see "Use of other medications"),
  • if you are allergic to other anti-inflammatory or antirheumatic medications,
  • if you have a glucose-6-phosphate dehydrogenase deficiency,
  • if you have had rhinitis or urticaria,
  • if you have recently undergone or are to undergo surgery in the next 7 days, including dental surgery,
  • if you are in your first or second trimester of pregnancy,
  • do not systematically administer to prevent possible discomfort caused by vaccinations.

Other medications and Aspirin

Tell your doctor or pharmacist if you are using or have recently used other medications, including those obtained without a prescription, homeopathic, herbal, and other health-related products, as it may be necessary to interrupt treatment or adjust the dose of one of them.

This is especially important in the case of:

  • other analgesics or non-steroidal anti-inflammatory medications (medicines used to treat pain and/or muscle inflammation),
  • certain antidepressants, such as selective serotonin reuptake inhibitors, as they increase the risk of bleeding,
  • anticoagulants (medicines used to "thin" the blood and prevent the formation of clots), such as warfarin,
  • oral antidiabetics (medicines to lower blood sugar levels),
  • barbiturates (medicines used to treat convulsions),
  • beta-blockers (medicines for blood pressure control),
  • cimetidine and ranitidine (used for stomach acidity),
  • medicines used to prevent transplant rejection (cyclosporine and tacrolimus),
  • corticosteroids, as they can increase the risk of gastrointestinal bleeding,
  • digoxin (heart medication),
  • high blood pressure (diuretics and ACE inhibitors),
  • phenytoin and valproic acid (antiepileptics),
  • interferon alpha (used to treat certain viral and tumor infections),
  • lithium (used in certain psychiatric illnesses),
  • cancer or rheumatoid arthritis (methotrexate),
  • medicines used to treat gout (probenecid),
  • vancomycin (antibiotic used for infections),
  • zidovudine (used in the treatment of patients infected with the human immunodeficiency virus, the cause of AIDS).

Interference with diagnostic tests

If you are going to have any diagnostic tests (including blood or urine tests), tell your doctor that you are taking this medicine, as it may alter the results.

Taking Aspirin with food, drinks, and alcohol

Take this medicine after meals or with some food.

If you regularly consume alcohol (three or more alcoholic beverages - beer, wine, liquor, ... - per day), taking Aspirin may cause stomach bleeding.

Pregnancy

Consult your doctor or pharmacist before using any medication.

If you are pregnant or think you may be pregnant, consult your doctor before taking this medicine.

Pregnancy - last trimester

Do not take Aspirin if you are in the last 3 months of pregnancy, as it may harm the fetus or cause problems during delivery. This medicine can cause kidney and heart problems in the fetus. It may affect your tendency to bleed and that of your baby, causing a possible delay in delivery or prolonging it more than expected.

Pregnancy - first and second trimester

Do not take Aspirin during the first 6 months of pregnancy unless it is absolutely necessary and your doctor advises you to do so. If you need treatment during this period or while trying to become pregnant, the dose will be limited to the lowest possible during the shortest time possible.

If you take Aspirin for several days from the 20th week of pregnancy, it may cause kidney problems in the fetus that could lead to low levels of amniotic fluid (oligohydramnios) or narrowing of a blood vessel (ductus arteriosus) in the baby's heart. If you need treatment for several days, your doctor may recommend additional monitoring.

Breastfeeding

Consult your doctor or pharmacist before using any medication.

Women who are breastfeeding should consult their doctor before using this medicine, as acetylsalicylic acid passes into breast milk.

Use in children

Do not administer to children under 16 years of age.

Use in adults over 65 years of age

Older adults should not take this medicine without consulting their doctor, as they are more likely to experience side effects.

Driving and using machines

No effects on the ability to drive or use machines have been described.

Aspirin contains phenylalanine and sodium

This medicine contains 5 mg of aspartame in each sachet. Aspartame is a source of phenylalanine that may be harmful in case of phenylketonuria (PKU), a rare genetic disease in which phenylalanine accumulates because the body is unable to eliminate it properly.

This medicine contains less than 1 mmol of sodium (23 mg) per sachet; it is essentially "sodium-free".

3. How to take Aspirin

Follow exactly the administration instructions of the medicine contained in this leaflet or as indicated by your doctor or pharmacist. In case of doubt, ask your doctor or pharmacist.

This medicine is administered orally.

Adults and adolescents over 16 years of age: 1 sachet (500 mg of acetylsalicylic acid) every 4 or 6 hours, if necessary. Do not exceed 8 sachets (4 g of acetylsalicylic acid) in 24 hours.

Patient with reduced liver or kidney function: consult your doctor, as the dose should be reduced.

The granules should be placed directly on the tongue. They disperse in saliva before swallowing, so it is not necessary to take them with water.

Take the medicine with meals or with some food, especially if you experience digestive discomfort.

Do not take this medicine on an empty stomach.

Always use the lowest effective dose.

The administration of this preparation is subject to the appearance of painful or febrile symptoms. As they disappear, this medication should be discontinued.

If the pain persists for more than 5 days, or the fever for more than 3 days, or the symptoms worsen or other symptoms appear, you should interrupt treatment and consult your doctor.

If you take more Aspirin than you should

The main symptoms of overdose are: headache, dizziness, ringing in the ears, blurred vision, drowsiness, sweating, rapid breathing, mental confusion, nausea, vomiting, and occasionally diarrhea.

It is recommended to take the package and the package leaflet of the medicine to the healthcare professional.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or go to a medical center immediately or call the Toxicology Information Service, phone: 91 562 04 20, indicating the medicine and the amount ingested.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everyone gets them.

Frequent side effects (may affect up to 1 in 10 people):

  • Gastrointestinal disorders, such as stomach ulcers, intestinal ulcers, gastrointestinal bleeding, abdominal pain, indigestion, heartburn, acidity, gastric discomfort, nausea, and vomiting.
  • Respiratory disorders, such as difficulty breathing (asthma, bronchospasm), nasal congestion, and rhinitis.
  • Urticaria, skin rashes, angioedema (inflammation and swelling that affects the face, lips, mouth, tongue, or throat, which can cause difficulty swallowing or breathing) and itching.
  • Hypoprothrombinemia (coagulation disorder) when administered in high doses.

Uncommon side effects (may affect up to 1 in 100 people):

  • Reye's Syndrome in children under 16 years of age with febrile conditions, flu, or chickenpox (see "Before taking Aspirin").
  • Liver disorders, especially in patients with juvenile arthritis.
  • Anemia.

With prolonged doses of acetylsalicylic acid, the following side effects have been observed, whose frequency cannot be established with precision: dizziness, ringing in the ears, deafness, sweating, headache, confusion, renal insufficiency, and acute interstitial nephritis.

If you notice the appearance of:

  • stomach discomfort or pain, gastrointestinal bleeding or black stools,
  • skin disorders, such as rashes or redness,
  • difficulty breathing,
  • unexpected changes in the amount or appearance of urine,
  • swelling of the face, feet, or legs,
  • deafness, ringing in the ears, or dizziness,

stop taking the medicine and consult your doctor immediately, as they may indicate the appearance of side effects that require urgent medical attention.

Reporting of side effects

If you experience any side effects, consult your doctor or pharmacist, even if they are not listed in this leaflet. You can also report them directly through the Spanish Medicines and Health Products Agency (AEMPS) https://notificaram.es. By reporting side effects, you can contribute to providing more information on the safety of this medicine.

5. Storage of Aspirin

Do not store above 25°C.

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiration date stated on the packaging, after the abbreviation CAD. The expiration date is the last day of the month indicated.

Medicines should not be disposed of via wastewater or household waste. Place the packaging and medicines you no longer need in the pharmacy's SIGRE point. If in doubt, ask your pharmacist how to dispose of the packaging and medicines you no longer need. This will help protect the environment.

6. Contents of the pack and further information

Composition of Aspirin

Each sachet contains as active ingredient: acetylsalicylic acid, 500 mg. The other ingredients (excipients) are: mannitol (E-421), aspartame (E-951), sodium hydrogen carbonate, sodium dihydrogen citrate, ascorbic acid (E-300), citric acid, orange flavor, and cola flavor.

Appearance of Aspirin and contents of the pack

White to slightly yellowish granules.

It is presented in packs containing 2, 10, or 20 sachets. Not all pack sizes may be marketed.

Marketing authorization holder

Bayer Hispania, S.L.

Av. Baix Llobregat, 3-5

08970 Sant Joan Despí (Barcelona)

Spain

Manufacturer

Bayer Bitterfeld GmbH

OT Greppin

Salegaster Chausee, 1

06803 Bitterfeld-Wolfen

Germany

Date of last revision of this leaflet:October 2023

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es

Online doctors for ASPIRIN 500 mg GRANULES

Discuss questions about ASPIRIN 500 mg GRANULES, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
Doctor
5.0(12)

Yevgen Yakovenko

General medicine12 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment
€72
Doctor
5.0(3)

Lina Travkina

General medicine13 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.

  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.

  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.

  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.

  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.

  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.

  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.

  • Medical advice and follow-up consultations.

  • Test interpretation and diagnostic guidance.

  • Structured support for undiagnosed complaints.

  • Second opinion on diagnoses and treatment plans.

  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.

  • Post-operative recovery support and pain management.

  • Preconception counselling and postpartum support.

  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Book a video appointment
€75
Doctor
5.0(21)

Nuno Tavares Lopes

General medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies

  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management

  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses

  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment

  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance

  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis

  • Pain management: acute and chronic pain, post-surgical care

  • Public health: prevention, health screenings, long-term monitoring

  • Sick leave (Baixa médica) connected to Segurança Social in Portugal

  • IMT medical certificates for driving licence exchange

Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Book a video appointment
€70

Get ASPIRIN 500 mg GRANULES Prescription Online

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Tell us your symptoms, history, and what medicine you're requesting.

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Electronic prescription sent to your email — valid across Spain.

Frequently Asked Questions

ASPIRIN 500 mg GRANULES does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

The active ingredient in ASPIRIN 500 mg GRANULES is acetylsalicylic acid. This information helps identify medicines with the same composition but different brand names.

ASPIRIN 500 mg GRANULES is manufactured by Bayer Hispania S.L.. Pharmacy brands and packaging may differ depending on the distributor.

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether ASPIRIN 500 mg GRANULES is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy ASPIRIN 500 mg GRANULES in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

Other medicines with the same active substance (acetylsalicylic acid) include A.A.S. 500 mg TABLETS, ASPIRIN 500 mg EFFERVESCENT TABLETS, ASPIRIN 500 mg TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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