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VERSATIS 700 MG MEDICATED ADHESIVE DRESSING

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About the medicine

How to use VERSATIS 700 MG MEDICATED ADHESIVE DRESSING

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Versatis 700 mg Medicinal Adhesive Patch

Lidocaine

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack

  1. What is Versatis and what is it used for
  2. What you need to know before you use Versatis
  3. How to use Versatis
  4. Possible side effects
  5. Storage of Versatis
  6. Contents of the pack and further information

1. What is Versatis and what is it used for

Versatis contains lidocaine, a local anesthetic, which acts by reducing pain in the skin.

You have been given Versatis to treat a painful skin problem called post-herpetic neuralgia. This problem is usually characterized by localized symptoms such as burning pain, stabbing pain, or shooting pain.

Doctor consultation

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2. What you need to know before you use Versatis

Do not use Versatis

  • if you are allergic to lidocaine or any of the other ingredients of this medicine (listed in section 6),
  • if you have had an allergic reaction to other products similar to lidocaine, such as bupivacaine, etidocaine, mepivacaine, or prilocaine,
  • on damaged skin or open wounds.

Warnings and precautions

Consult your doctor or pharmacist before you start using Versatis.

If you have a severe liver disease, or severe heart problems, or severe kidney problems, you should talk to your doctor before using Versatis.

Versatis should only be used on areas of the skin after the skin has healed completely. It should not be used in or near the eyes or mouth.

Lidocaine is broken down in the liver into several compounds. One of these compounds is 2,6-xylidine, which has been shown to produce tumors in rats when administered for life at very high doses. The importance of these findings in humans is unknown.

Children and adolescents

Versatis has not been studied in patients under 18 years of age. Therefore, it is not recommended for use in this patient population.

Using Versatis with other medicines

Tell your doctor or pharmacist if you are using, have recently used, or might use any other medicines.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

Versatis should not be used during pregnancy, unless clearly necessary.

No studies have been conducted with the adhesive patch in breastfeeding women. When using Versatis, only very small amounts of the active ingredient lidocaine may be present in the blood. It is unlikely to have an effect on breastfed babies.

Driving and using machines

It is unlikely that Versatis will affect your ability to drive or use machines. Therefore, you can drive or operate machinery while using Versatis.

Versatis contains propylene glycol, methyl parahydroxybenzoate, and propyl parahydroxybenzoate

The patches contain propylene glycol (E1520), a substance that may cause skin irritation. They also contain methyl parahydroxybenzoate (E218) and propyl parahydroxybenzoate (E216), substances that may cause allergic reactions. Sometimes, allergic reactions can occur after using the patch for some time.

3. How to use Versatis

Follow exactly the administration instructions of this medicine given by your doctor. If you are in doubt, consult your doctor or pharmacist again.

The recommended daily dose consists of covering the painful areas of the skin using one to three patches. Versatis can be cut into smaller pieces to fit the affected area. Do not use more than 3 patches at the same time.

The patches should be removed after 12 hours of use, and a 12-hour patch-free period should follow.

You can choose to apply Versatis during the day or during the night.

Usually, you will have some pain relief on the first day you use the patch, but it may take up to 2-4 weeks until you see the full effect of Versatis on pain relief. If after that time you still have a lot of pain, talk to your doctor, because the benefits of treatment should be weighed against the possible risks (see section 2 "Warnings and precautions").

Your doctor will check at regular intervals if Versatis is working well.

Before applying Versatis to the affected area

  • If the painful area of the skin has hair, you can cut the hair using scissors. Do not shave.
  • The skin must be clean and dry.
  • Creams and lotions can be used on the affected skin during the period when you are not using the patch.
  • If you have recently taken a bath or shower, you should wait until the skin cools down before using the patch.

Applying the patch

Step 1: Open the envelope and remove one or more patches

Fine-tip scissors cutting a strip of white material with dotted lines on a gray backgroundHand holding a blister pack of white tablets over another empty blister pack with space to extract tablets

? Open the envelope by tearing or cutting along the dotted line

? When using scissors, be careful not to damage the patches

? Remove one or more patches depending on the size of the painful area of the skin

Step 2: Close the envelope

Hand applying pressure on a rectangular medicinal patch with an arrow indicating the direction of application

  • Close the envelope hermetically after use
  • The patch contains water and will dry out if the envelope is not closed properly

Step 3: Cut the patch, if necessary

Steel scissors open, cutting a straight line on a white paper sheet

  • If necessary, cut the patch to fit the size of the painful area of the skin before removing the protective liner

Step 4: Remove the protective liner

Hand holding an applicator with a retractable needle and pulling the protector of the needle with an arrow indicating the direction

  • Remove the transparent liner from the adhesive patch
  • Try not to touch the adhesive part of the patch

Step 5: Apply the patch and press firmly on the skin

Hand pinching the abdominal skin with the thumb and index finger forming a fold for injection

  • Apply up to three patches to the painful area of the skin
  • Press the patch onto the skin
  • Press for at least 10 seconds to ensure the patch adheres firmly
  • Make sure the entire patch adheres to the skin, including the edges

Leave the adhesive patch on for only 12 hours

Digital clock showing 12:00 hours with two white patches and arrows indicating their application on the skin

It is important that Versatis is in contact with the skin for only 12 hours. For example, if you have more pain at night, you may want to apply the patch at 7 pm and remove it at 7 am.

If you have more pain during the day than at night, you may want to apply Versatis at 7 am and remove it at 7 pm.

Baths, showers, and swimming

If possible, contact with water should be avoided while using Versatis. You can bathe, shower, or swim during the time when you are not wearing the patch. If you have recently taken a bath or shower, you should wait until the skin cools down before using the patch.

If the patch comes off

Very rarely, the patch may fall off or come loose. If it does, try to reapply it to the same area. If it does not stay in place, remove it and apply a new patch to the same area.

How to remove Versatis

When changing patches, remove the old patch slowly. If it does not come off easily, you can soak it in warm water for a few minutes before removing it.

If you forget to remove the patch after 12 hours

As soon as you remember, remove the old patch. You can use a new patch again after 12 hours.

If you use more patches than you should

If you use more patches than necessary or wear them for too long, this may increase the risk of side effects.

In case of overdose or accidental ingestion, consult the Toxicology Information Service, phone 91 562 04 20.

If you forget to use Versatis

After the 12-hour patch-free period, if you have forgotten to use a new patch, you should apply a new patch as soon as you remember.

If you have any other questions about the use of this medicine, ask your doctor or pharmacist.

Medicine questions

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4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Important side effects or symptoms to look out for and what to do if you are affected:

If irritation or a burning sensation occurs while using the adhesive patch, the patch should be removed. The irritated area should remain without a patch until the irritation stops.

Other side effects that may occur:

Very common (may affect more than 1 in 10 people):Skin problems at or around the patch application site, which may include redness, rash, itching, burning, dermatitis, and small blisters.

Uncommon (may affect up to 1 in 100 people):Skin lesions and skin wounds.

Very rare (may affect up to 1 in 10,000 people):Open wound, severe allergic reaction, and allergy.

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Versatis

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the envelope and on the carton after "EXP". The expiry date is the last day of the month shown.

Do not refrigerate or freeze.

After first opening: Keep the envelope hermetically closed to protect it from light.

Shelf life after first opening of the envelope: 14 days.

Do not use this medicine if you notice that the envelope has been damaged. If this has happened, the patches may dry out and not adhere properly.

Disposal of Versatis

Used patches still contain active ingredient, which can be harmful to others. Fold used patches in half, joining the adhesive sides, and dispose of them in a way that they are out of the reach of children.

Medicines should not be disposed of via wastewater or household waste. Place the empty packaging and any unused medicine in the SIGRE collection point at your pharmacy. If you have any further questions, ask your pharmacist how to dispose of the packaging and any unused medicine. This will help protect the environment.

6. Contents of the pack and further information

Composition of Versatis

  • The active substance is lidocaine.
  • Each adhesive patch of 14 cm x 10 cm contains 700 mg (equivalent to 5% w/w) of lidocaine.
  • The other ingredients of the patch (excipients) are glycerol, liquid sorbitol, sodium carmellose, propylene glycol (E1520), urea, heavy kaolin, tartaric acid, gelatin, polyvinyl alcohol, aluminum glycinates, disodium edetate, methyl parahydroxybenzoate (E218), propyl parahydroxybenzoate (E216), polyacrylic acid, sodium polyacrylate, purified water.

Supporting tissue and release liner: polyethylene terephthalate (PET)

Appearance of the product and contents of the pack

The medicinal patch measures 14 cm in length and 10 cm in width. It is white and made of non-woven textile material, marked with "Lidocaine 5%". The adhesive patches are packaged in hermetically sealed envelopes, each containing 5 patches.

Each carton contains 5, 10, 20, 25, or 30 patches packaged in 1, 2, 4, 5, or 6 envelopes, respectively. Some pack sizes may not be marketed.

Marketing authorization holder and manufacturer

Marketing authorization holder:

Grünenthal Pharma, S.A.

Doctor Zamenhof, 36 – 28027 Madrid

Manufacturer:

Grünenthal GmbH

Zieglerstrasse 6

52078 Aachen

Germany

This medicine is authorized in the Member States of the European Economic Area under the following names:

Germany, Austria, Belgium, Bulgaria, Cyprus, Denmark, Slovenia, Spain, Estonia, France, Greece, Netherlands, Hungary, Ireland, Iceland, Italy, Latvia, Lithuania, Luxembourg, Malta, Norway, Poland, United Kingdom, Czech Republic, Slovak Republic, Romania, Sweden: Versatis

Portugal: Vessatis

Date of last revision of this leaflet: May 2018.

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

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Frequently Asked Questions

Is a prescription required for VERSATIS 700 MG MEDICATED ADHESIVE DRESSING?
VERSATIS 700 MG MEDICATED ADHESIVE DRESSING requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in VERSATIS 700 MG MEDICATED ADHESIVE DRESSING?
The active ingredient in VERSATIS 700 MG MEDICATED ADHESIVE DRESSING is lidocaine. This information helps identify medicines with the same composition but different brand names.
How much does VERSATIS 700 MG MEDICATED ADHESIVE DRESSING cost in pharmacies?
The average pharmacy price for VERSATIS 700 MG MEDICATED ADHESIVE DRESSING is around 77.94 EUR. Prices may vary depending on the manufacturer and dosage form.
Who manufactures VERSATIS 700 MG MEDICATED ADHESIVE DRESSING?
VERSATIS 700 MG MEDICATED ADHESIVE DRESSING is manufactured by Grünenthal Pharma S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of VERSATIS 700 MG MEDICATED ADHESIVE DRESSING online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether VERSATIS 700 MG MEDICATED ADHESIVE DRESSING is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to VERSATIS 700 MG MEDICATED ADHESIVE DRESSING?
Other medicines with the same active substance (lidocaine) include ACTILOGIC 700 MG MEDICATED ADHESIVE DRESSING, DYNEXAN 20 mg/g BUCAL GEL, INSTILLIDO 20 mg/ml GEL. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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