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VARIDASA COMPRESSES

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use VARIDASA COMPRESSES

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

PACKAGE LEAFLET: INFORMATION FOR THE USER

VARIDASA Tablets

Streptokinase and Streptodornase

Read all of this leaflet carefully before you start taking this medicine.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you, do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet.

Contents of the pack:

  1. What VARIDASA Tablets are and what they are used for
  2. Before you take VARIDASA Tablets
  3. How to take VARIDASA Tablets
  4. Possible side effects
  5. Storing VARIDASA Tablets
  6. Further information

1. What VARIDASA Tablets are and what they are used for

Varidasa belongs to a group of medicines called antithrombotics.

Varidasa is indicated for the treatment of acute or chronic inflammation, infectious in combination with antibiotics or traumatic (with edema and/or hematoma).

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. BEFORE YOU TAKE VARIDASA Tablets

Do not take Varidasa

  • If you are allergic (hypersensitive) to streptokinase, streptodornase or any of the other ingredients of this medicine.
  • If you have bleeding disorders (known hemorrhagic diathesis).
  • If you have severe uncontrolled hypertension.
  • If you have low fibrinogen levels.
  • If you have low platelet counts in the blood (thrombocytopenia).

Be careful with Varidasa

In case of an allergic reaction, including anaphylactic shock, dyspnea (difficulty breathing) and urticaria, treatment with Varidasa should be discontinued.

Special precautions should be taken when administering Varidasa to patients with the following conditions:

  • Recent severe gastrointestinal bleeding.
  • Recent major surgery (6th to 10th postoperative day, depending on the severity of the surgery).
  • Recent trauma and cardiopulmonary resuscitation.
  • Recent biopsy of any organ, punctures in non-compressible vessels, intramuscular injections or intubation.
  • Recent childbirth, abortion.
  • Patients with concomitant treatment with oral anticoagulants (INR>1.3).
  • Severe liver or kidney damage.
  • Organic lesions that may bleed (e.g. active peptic ulcer).
  • Acute pericarditis and/or subacute bacterial endocarditis.
  • Active internal bleeding, existing or recent.
  • Recent stroke; intracranial or intraspinal surgery.
  • Intracranial neoplasia.
  • Recent head trauma.
  • Known neoplasia with risk of bleeding.
  • Acute pancreatitis.
  • Hypertensive retinopathy grade III/IV.

Varidasa should be used with caution in patients with a history of decreased liver function.

Using other medicines

Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including those obtained without a prescription.

Prior or simultaneous treatment with Varidasa and anticoagulants or substances that act on platelet formation or function (e.g. platelet aggregation inhibitors, dextran, antifibrinolytics such as aminocaproic acid, aprotinin and tranexamic acid, non-steroidal anti-inflammatory analgesics especially acetylsalicylic acid, indomethacin, phenylbutazone and other platelet aggregation inhibitors especially sulfinpyrazone) could increase the risk of bleeding.

Pregnancy and breastfeeding

Consult your doctor or pharmacist before taking any medicine.

The safety and efficacy of Varidasa during pregnancy and breastfeeding have not been established, so its use is not recommended in these situations.

Use in children

Varidasa is not recommended for use in patients under 18 years of age, as its safety and efficacy have not been established in these patients.

Driving and using machines

No effects on the ability to drive or operate machinery have been described.

Important information about some of the ingredients of Varidasa:

Varidasa contains the yellow-orange S dye (E-110), which may cause allergic reactions.

3. HOW TO TAKE VARIDASA Tablets

Follow exactly the administration instructions of Varidasa indicated by your doctor. Consult your doctor or pharmacist if you have any doubts.

Your doctor will indicate the duration of your treatment with Varidasa. Do not stop treatment before, as it may not have the desired effect.

Varidasa tablets are for oral administration.

The recommended average dose is one tablet, four times a day, for 4-6 days.

In acute conditions, higher doses may be used as a therapeutic attack measure, consisting of two tablets three times a day, and if necessary, the dose may be increased to two tablets four times a day.

If you take more Varidasa than you should

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately, or call the Toxicology Information Service, phone 91 562 04 20 (indicating the medicine and the amount ingested).

If you forget to take Varidasa

If you forget a dose of the medicine, take the next dose when it is due. Do not take a double dose to make up for the forgotten doses.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, Varidasa can have side effects, although not everybody gets them.

The following side effects have been described, according to the frequency categories indicated below:

Very common:at least 1 in 10 patients

Common:at least 1 in 100 patients

Uncommon:at least 1 in 1,000 patients

Rare:at least 1 in 10,000 patients

Very rare:less than 1 in 10,000 patients

Immune system disorders

Common:Development of anti-streptokinase antibodies.

Uncommon:Hypersensitivity and allergic reactions including anaphylactic shock, dyspnea (difficulty breathing) and urticaria.

Gastrointestinal disorders

Uncommon:Nausea, diarrhea, epigastric pain, vomiting.

Skin and subcutaneous tissue disorders

Very rare:Erythematous exanthema (inflammatory lesion at the site of administration), dermatitis, pruritus.

Hepatobiliary disorders

Uncommon:Transient increase in liver enzymes (transaminases) and bilirubin.

General disorders

Uncommon:Headache, back pain (dorsalgia), muscle pain (myalgia), chills and/or increased body temperature, feeling of weakness (asthenia), general malaise.

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet.

5. Storing VARIDASA Tablets

Keep Varidasa out of the reach and sight of children.

Store in the original packaging to protect from light and moisture.

Do not store above 30°C.

Do not use Varidasa after the expiry date stated on the carton. The expiry date is the last month indicated.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. FURTHER INFORMATION

Composition of Varidasa Tablets

  • The active ingredients are streptokinase and streptodornase. Each tablet contains 10,000 International Units and 2,500 Units of streptodornase.
  • The other ingredients are dibasic calcium phosphate dihydrate, corn starch, acacia, magnesium stearate, and yellow-orange S dye (E-110).

Appearance and packaging of the product

Varidasa are orange-colored scored tablets. They are available in packs of 20 or 40 tablets.

Marketing authorization holder

INDUSTRIAL FARMACEUTICA CANTABRIA, S.A.

Carretera Cazoña-Adarzo, s/n.

39011 – Santander

Manufacturer

Toll Manufacturing Services S.L.

Aragoneses, 2

28108 – Alcobendas (Madrid)

This leaflet was approved in: May 2007

Online doctors for VARIDASA COMPRESSES

Discuss questions about VARIDASA COMPRESSES, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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€58
5.0 (5)
Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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€80
5.0 (1038)
Doctor

Andrei Popov

General medicine 7 years exp.

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

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€80
5.0 (180)
Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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€50
5.0 (41)
Doctor

Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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€60

Frequently Asked Questions

Is a prescription required for VARIDASA COMPRESSES?
VARIDASA COMPRESSES requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in VARIDASA COMPRESSES?
The active ingredient in VARIDASA COMPRESSES is streptokinase. This information helps identify medicines with the same composition but different brand names.
How much does VARIDASA COMPRESSES cost in pharmacies?
The average pharmacy price for VARIDASA COMPRESSES is around 2.5 EUR. Prices may vary depending on the manufacturer and dosage form.
Who manufactures VARIDASA COMPRESSES?
VARIDASA COMPRESSES is manufactured by Industrial Farmaceutica Cantabria S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of VARIDASA COMPRESSES online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether VARIDASA COMPRESSES is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to VARIDASA COMPRESSES?
Other medicines with the same active substance (streptokinase) include ERNODASA HARD CAPSULES, ACTILYSE powder and solvent for injectable solution and for infusion, ADZYNMA 1500 IU POWDER AND SOLVENT FOR INJECTABLE SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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