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SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION

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About the medicine

How to use SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Supliven Concentrate for Solution for Infusion

Oligoelements

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack:

  1. What Supliven is and what it is used for
  2. What you need to know before you use Supliven
  3. How to use Supliven
  4. Possible side effects
  5. Storage of Supliven
  6. Contents of the pack and other information

1. What Supliven is and what it is used for

Supliven is a medicine that contains oligoelements. Oligoelements are small amounts of chemical substances that your body needs to function properly. Supliven is administered intravenously (in a vein) if you are an adult or a child with a weight of 15 kg or more, who cannot eat normally.

This medicine is usually used as part of a balanced intravenous diet, along with proteins, fats, carbohydrates, salts, and vitamins.

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2. What you need to know before you use Supliven

Do not use Supliven:

  • if you are allergic to the active substances or to any of the other components of this medicine (listed in section 6). If a rash or other allergic reactions appear (such as itching, swelling of the lips or face, or difficulty breathing), inform your doctor immediately.
  • if you have blocked bile ducts
  • if you have Wilson's disease (a genetic disease that causes copper accumulation in the liver) or hemochromatosis (iron accumulation in the body)

Supliven should not be administered to children weighing less than 15 kg.

Warnings and precautions

Tell your doctor if you have liver or kidney problems.

Your doctor may perform periodic blood tests to monitor your condition. If you are taking oral iron in parallel with the infusion, your doctor may want to ensure that you do not accumulate iron in your body.

Iron and iodine can cause allergic reactions in rare cases when administered as a drip. Inform your doctor or nurse if you have allergic reactions when Supliven is administered.

Tell your doctor or pharmacist if you have problems with your thyroid gland (hyperthyroidism).

Using Supliven with other medicines

Tell your doctor or pharmacist that you are using, have recently used, or may need to use any other medicine.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor before using this medicine.

Although the need for oligoelements is slightly increased in pregnant women, there are no safety data for the administration of Supliven during pregnancy. Therefore, Supliven should not be administered during pregnancy, unless it is absolutely necessary.

The active substances of Supliven are excreted in breast milk, and effects have been observed in infants whose mothers were treated with this medicine. Supliven should only be administered to breastfeeding women if they need to obtain oligoelements through parenteral nutrition.

Driving and using machines

Supliven has no effect on driving or using machines.

3. How to use Supliven

This medicine will be administered by healthcare personnel.

You will receive the medicine through an intravenous drip directly into a vein.

Your doctor will decide the appropriate dose for you to receive.

The recommended dose for adults is 10 ml (one ampoule) per day. If you have liver or kidney problems, you may be given a lower dose.

Before administration, Supliven must be added to another solution. Your doctor or nurse will ensure that the medicine is prepared correctly before administering it to you.

Use in children

The recommended dose for children weighing more than 15 kg is 0.1 ml per kg of body weight per day.

If you are given too much Supliven

It is unlikely that you will receive more medicine than you should, as your doctor or nurse will monitor you during treatment. However, if you think you are being given too much Supliven, inform your doctor or nurse immediately.

If you have any further questions about the use of this medicine, ask your doctor or pharmacist.

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4. Possible side effects

Like all medicines, Supliven can cause side effects, although not everybody gets them.

No side effects have been observed due to the use of Supliven according to the recommended instructions.

Some cases of superficial thrombophlebitis have been observed after the administration of glucose-containing Addamel. However, it has been impossible to confirm whether this reaction was caused by the oligoelements.

Reporting of side effects

If you experience any side effects, talk to your doctor or nurse, even if it is possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Medicines Monitoring System: www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Supliven

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiry date is the last day of the month shown.

This medicine does not require any special storage conditions.

The hospital doctor and pharmacist are responsible for the correct storage, use, and disposal of Supliven.

After dilution: The addition of Supliven should be performed immediately before the start of the infusion and should be used within 24 hours. If not used immediately, the storage times and conditions before use are the responsibility of the user and should not normally exceed 24 hours at 2-8°C, unless the mixture has been prepared in controlled and validated aseptic conditions.

Any remaining solution after treatment should be disposed of according to the standard hospital procedures.

6. Contents of the pack and other information

Composition of Supliven concentrate for solution for infusion

  • The active substances contained in one ampoule (10 ml) are:

Chromium chloride hexahydrate 53.3 μg

Copper chloride dihydrate 1.02 mg

Iron chloride hexahydrate 5.40 mg

Manganese chloride tetrahydrate 198 μg

Potassium iodide 166 μg

Sodium fluoride 2.10 mg

Sodium molybdate dihydrate 48.5 μg

Sodium selenite anhydrous 173 μg

Zinc chloride 10.5 mg

  • The other components are: xylitol, hydrochloric acid, water for injections.

This product contains 0.052 mmol of sodium (1.2 mg) per dose (10 ml).

Appearance and pack size

Supliven is a clear, almost colorless solution of oligoelements presented in polypropylene ampoules containing 10 ml of concentrate. The pack size is 20 ampoules of 10 ml.

Marketing authorisation holder and manufacturer

Marketing authorisation holder

FRESENIUS KABI ESPAÑA S.A.U

Calle Marina 16-18

08005-Barcelona

Manufacturer

HP Halden Pharma AS

Svinesundsveien 80

1788 Halden

Norway

Revision date of this leaflet:June 2016

Detailed and up-to-date information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION

Discuss questions about SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
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  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
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He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques.

For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance.

Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults.

In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions.

Patients commonly seek his care for:

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Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.
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Doctor

Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
  • Structured support for undiagnosed complaints.
  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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€70
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Doctor

Alina Tsurkan

Family medicine 13 years exp.

Dr. Alina Tsurkan is a licensed family medicine physician based in Portugal, offering online consultations for adults and children. She provides professional primary care, with a focus on prevention, accurate diagnosis, and long-term management of acute and chronic conditions.

Dr. Tsurkan supports patients with a wide range of health issues, including:

  • Respiratory infections: cold, flu, bronchitis, pneumonia, and lingering coughs.
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  • Eye conditions: allergic or infectious conjunctivitis, red eyes, irritation.
  • Digestive issues: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), constipation, bloating, nausea.
  • Urinary and reproductive health: urinary tract infections (UTIs), cystitis, prevention of recurrent infections.
  • Chronic diseases: hypertension, elevated cholesterol, weight management.
  • Neurological complaints: headaches, migraines, sleep disturbances, fatigue, general weakness.
  • Children’s health: fever, infections, digestive issues, follow-ups, vaccination guidance.

She also provides:

  • IMT medical certificates for driving licence exchange in Portugal.
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€55
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Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Frequently Asked Questions

Is a prescription required for SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION?
SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION?
The active ingredient in SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION is electrolytes in combination with other drugs. This information helps identify medicines with the same composition but different brand names.
Who manufactures SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION?
SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION is manufactured by Fresenius Kabi España, S.A.U.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION?
Other medicines with the same active substance (electrolytes in combination with other drugs) include INFUTRAZE CONCENTRATE FOR PERFUSION SOLUTION, POTASSIUM ACETATE B.BRAUN 1 mEq/ml CONCENTRATE FOR INFUSION SOLUTION, SODIUM BICARBONATE 1/6 M MEIN SOLUTION FOR INFUSION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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