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SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION

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About the medicine

How to use SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Supliven Concentrate for Solution for Infusion

Oligoelements

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack:

  1. What Supliven is and what it is used for
  2. What you need to know before you use Supliven
  3. How to use Supliven
  4. Possible side effects
  5. Storage of Supliven
  6. Contents of the pack and other information

1. What Supliven is and what it is used for

Supliven is a medicine that contains oligoelements. Oligoelements are small amounts of chemical substances that your body needs to function properly. Supliven is administered intravenously (in a vein) if you are an adult or a child with a weight of 15 kg or more, who cannot eat normally.

This medicine is usually used as part of a balanced intravenous diet, along with proteins, fats, carbohydrates, salts, and vitamins.

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2. What you need to know before you use Supliven

Do not use Supliven:

  • if you are allergic to the active substances or to any of the other components of this medicine (listed in section 6). If a rash or other allergic reactions appear (such as itching, swelling of the lips or face, or difficulty breathing), inform your doctor immediately.
  • if you have blocked bile ducts
  • if you have Wilson's disease (a genetic disease that causes copper accumulation in the liver) or hemochromatosis (iron accumulation in the body)

Supliven should not be administered to children weighing less than 15 kg.

Warnings and precautions

Tell your doctor if you have liver or kidney problems.

Your doctor may perform periodic blood tests to monitor your condition. If you are taking oral iron in parallel with the infusion, your doctor may want to ensure that you do not accumulate iron in your body.

Iron and iodine can cause allergic reactions in rare cases when administered as a drip. Inform your doctor or nurse if you have allergic reactions when Supliven is administered.

Tell your doctor or pharmacist if you have problems with your thyroid gland (hyperthyroidism).

Using Supliven with other medicines

Tell your doctor or pharmacist that you are using, have recently used, or may need to use any other medicine.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor before using this medicine.

Although the need for oligoelements is slightly increased in pregnant women, there are no safety data for the administration of Supliven during pregnancy. Therefore, Supliven should not be administered during pregnancy, unless it is absolutely necessary.

The active substances of Supliven are excreted in breast milk, and effects have been observed in infants whose mothers were treated with this medicine. Supliven should only be administered to breastfeeding women if they need to obtain oligoelements through parenteral nutrition.

Driving and using machines

Supliven has no effect on driving or using machines.

3. How to use Supliven

This medicine will be administered by healthcare personnel.

You will receive the medicine through an intravenous drip directly into a vein.

Your doctor will decide the appropriate dose for you to receive.

The recommended dose for adults is 10 ml (one ampoule) per day. If you have liver or kidney problems, you may be given a lower dose.

Before administration, Supliven must be added to another solution. Your doctor or nurse will ensure that the medicine is prepared correctly before administering it to you.

Use in children

The recommended dose for children weighing more than 15 kg is 0.1 ml per kg of body weight per day.

If you are given too much Supliven

It is unlikely that you will receive more medicine than you should, as your doctor or nurse will monitor you during treatment. However, if you think you are being given too much Supliven, inform your doctor or nurse immediately.

If you have any further questions about the use of this medicine, ask your doctor or pharmacist.

Medicine questions

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4. Possible side effects

Like all medicines, Supliven can cause side effects, although not everybody gets them.

No side effects have been observed due to the use of Supliven according to the recommended instructions.

Some cases of superficial thrombophlebitis have been observed after the administration of glucose-containing Addamel. However, it has been impossible to confirm whether this reaction was caused by the oligoelements.

Reporting of side effects

If you experience any side effects, talk to your doctor or nurse, even if it is possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Medicines Monitoring System: www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Supliven

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiry date is the last day of the month shown.

This medicine does not require any special storage conditions.

The hospital doctor and pharmacist are responsible for the correct storage, use, and disposal of Supliven.

After dilution: The addition of Supliven should be performed immediately before the start of the infusion and should be used within 24 hours. If not used immediately, the storage times and conditions before use are the responsibility of the user and should not normally exceed 24 hours at 2-8°C, unless the mixture has been prepared in controlled and validated aseptic conditions.

Any remaining solution after treatment should be disposed of according to the standard hospital procedures.

6. Contents of the pack and other information

Composition of Supliven concentrate for solution for infusion

  • The active substances contained in one ampoule (10 ml) are:

Chromium chloride hexahydrate 53.3 μg

Copper chloride dihydrate 1.02 mg

Iron chloride hexahydrate 5.40 mg

Manganese chloride tetrahydrate 198 μg

Potassium iodide 166 μg

Sodium fluoride 2.10 mg

Sodium molybdate dihydrate 48.5 μg

Sodium selenite anhydrous 173 μg

Zinc chloride 10.5 mg

  • The other components are: xylitol, hydrochloric acid, water for injections.

This product contains 0.052 mmol of sodium (1.2 mg) per dose (10 ml).

Appearance and pack size

Supliven is a clear, almost colorless solution of oligoelements presented in polypropylene ampoules containing 10 ml of concentrate. The pack size is 20 ampoules of 10 ml.

Marketing authorisation holder and manufacturer

Marketing authorisation holder

FRESENIUS KABI ESPAÑA S.A.U

Calle Marina 16-18

08005-Barcelona

Manufacturer

HP Halden Pharma AS

Svinesundsveien 80

1788 Halden

Norway

Revision date of this leaflet:June 2016

Detailed and up-to-date information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

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Jorge Correa Bellido

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Dr. Jorge Correa Bellido is a Spanish physician who offers online consultations in Spanish and English. He graduated from the University of La Laguna and has a solid background in clinical practice and international research.

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Daniel Cichi

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Dr Daniel Cichi is a family medicine doctor with over 20 years of clinical experience. He provides online consultations for adults, supporting patients with acute symptoms, chronic conditions, and everyday health concerns that require timely medical guidance. His background includes work in emergency care, ambulance services, and family medicine, which allows him to assess symptoms quickly, identify warning signs, and help patients choose the safest next steps – whether that means home care, treatment adjustment, or in-person evaluation. Patients commonly consult Dr Daniel Cichi for: 

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Chikeluo Okeke

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Dr Chikeluo Okeke is an internal medicine doctor with extensive international clinical experience. Originally from Nigeria, he has worked across multiple European healthcare systems and currently practises in Sweden. This professional path has given him a strong understanding of different medical approaches and the ability to work effectively with patients from diverse cultural and linguistic backgrounds.

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Nuno Tavares Lopes

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Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

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Lina Travkina

Family medicine 13 years exp.

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Anastasiia Shalko

Family medicine 13 years exp.

Dr. Anastasiia Shalko is a general practitioner with a background in both paediatrics and general medicine. She graduated from Bogomolets National Medical University in Kyiv and completed her paediatric internship at the P.L. Shupyk National Medical Academy of Postgraduate Education. After working as a paediatrician in Kyiv, she relocated to Spain, where she has been practising general medicine since 2015, providing care for both adults and children.Her work focuses on urgent, short-term medical concerns – situations where patients need quick guidance, symptom assessment and clear next steps. She helps people understand whether their symptoms require in-person evaluation, home management or a change in treatment. Common reasons for booking an online consultation include:

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  • viral illnesses such as colds and seasonal infections
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Dr. Shalko works specifically with urgent and short-term problems, providing practical recommendations and helping patients determine the safest next step. She explains symptoms clearly, guides patients through decision-making and offers straightforward medical advice for everyday acute issues.She does not provide long-term management of chronic conditions, ongoing follow-up or comprehensive care plans for complex long-term illnesses. Her consultations are designed for acute symptoms, sudden concerns and situations where timely medical input is important.With clinical experience in both paediatrics and general medicine, Dr. Shalko confidently supports adults and children. Her communication style is clear, simple and reassuring, helping patients feel informed and supported throughout the consultation.

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Bulat Garipov

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Dr. Bulat Garipov is a radiologist with more than 15 years of experience, specializing in magnetic resonance imaging (MRI). Throughout his professional career, he has worked in leading diagnostic imaging centers, both in on-site practice and teleradiology, which has allowed him to develop a broad and versatile approach to radiology.

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You could consult Dr. Bulat Garipov in cases where accurate interpretation of MRI studies or a second expert opinion is required. His expertise is especially valuable in cases of suspected neurological conditions, back and joint pain, vascular disorders, as well as in the diagnosis of abdominal and pelvic diseases. The doctor also provides support in complex or unclear clinical situations, including the review of previously performed studies, which helps improve diagnostic accuracy and determine the optimal treatment strategy. A teleradiology format is available, allowing you to receive a professional opinion remotely.

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Frequently Asked Questions

Is a prescription required for SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION?
SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION?
The active ingredient in SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION is electrolytes in combination with other drugs. This information helps identify medicines with the same composition but different brand names.
Who manufactures SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION?
SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION is manufactured by Fresenius Kabi España, S.A.U.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to SUPLIVEN CONCENTRADO FOR PERFUSION SOLUTION?
Other medicines with the same active substance (electrolytes in combination with other drugs) include INFUTRAZE CONCENTRATE FOR PERFUSION SOLUTION, POTASSIUM ACETATE B.BRAUN 1 mEq/ml CONCENTRATE FOR INFUSION SOLUTION, SODIUM BICARBONATE 1/6 M MEIN SOLUTION FOR INFUSION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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