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COLIROFTA ANESTHETIC 5 mg/ml + 0.5 mg/ml EYE DROPS SOLUTION

COLIROFTA ANESTHETIC 5 mg/ml + 0.5 mg/ml EYE DROPS SOLUTION

Ask a doctor about a prescription for COLIROFTA ANESTHETIC 5 mg/ml + 0.5 mg/ml EYE DROPS SOLUTION

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Doctor

Hocine Lokchiri

General medicine20 years of experience

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use COLIROFTA ANESTHETIC 5 mg/ml + 0.5 mg/ml EYE DROPS SOLUTION

Introduction

Leaflet: Information for the user

COLIROFTA ANESTHETIC 5 mg/ml + 0.5 mg/ml eye drops solution

Tetracaine hydrochloride/Naphazoline hydrochloride

Read the entire leaflet carefully before starting to use this medicine, as it contains important information for you.

  • Keep this leaflet, as you may need to read it again.
  • If you have any questions, consult your doctor or pharmacist.
  • This medicine has been prescribed to you only, and you should not give it to others, even if they have the same symptoms as you, as it may harm them.
  • If you experience side effects, consult your doctor or pharmacist, even if they are not listed in this leaflet. See section 4.

Contents of the leaflet

  1. What COLIROFTA ANESTHETIC is and what it is used for
  2. What you need to know before starting to use COLIROFTA ANESTHETIC
  3. How to use COLIROFTA ANESTHETIC
  4. Possible side effects

5 Conservation of COLIROFTA ANESTHETIC

  1. Package contents and additional information

1. What COLIROFTA ANESTHETIC is and what it is used for

It is an eye drop that contains two active ingredients, tetracaine, a local anesthetic (temporarily numbs the area of administration), and naphazoline with decongestant action (produces vasoconstriction or narrowing of the visible blood vessels in the eye), which prolongs the anesthetic activity.

Colirofta Anesthetic is indicated for the treatment of painful eye conditions, removal of foreign bodies, eye examination, tonometry (measurement of pressure inside the eyes), gonioscopy (measures the angle of the iris and cornea, whether it is wide or narrow), and fundus examination with contact lens.

2. What you need to know before starting to use COLIROFTA ANESTHETIC

Do not use Colirofta Anesthetic

  • If you are allergic to naphazoline, tetracaine, or other local anesthetics of the same type, or to any of the other components of this medicine (listed in section 6).
  • If you have narrow-angle glaucoma.

Warnings and precautions

Consult your doctor or pharmacist before starting to use Colirofta Anesthetic.

Use this medicine only in the eye(s).

You should be cautious if you are in any of the following situations:

  • If you are being treated with monoamine oxidase inhibitors (MAOIs) (usually antidepressants) or during the two weeks after stopping such treatment.
  • In case you are being administered certain anesthetics (e.g., halothane, which makes the heart more sensitive to medications of the naphazoline type).
  • If you have bronchial asthma.
  • If you have any heart or circulation disease.
  • If you have cerebral arteriosclerosis.
  • If you have hypertension.
  • If you have hyperthyroidism (excessive functioning of the thyroid gland).
  • If you have diabetes.

The repeated use of this medicine (due to tetracaine) may cause corneal ulcers.

With continued use of tetracaine, a decrease in the duration of anesthesia and delayed healing may occur, among other visual side effects.

  • Due to the anesthetic effect, your eyes will lose sensitivity, and you should be careful to avoid accidental injuries to the eyes.
  • This medicine should only be used under the direct supervision of a healthcare professional.
  • Do not use for more than 3 to 5 days.
  • Do not wear contact lenses during the use of this medicine.

Use in elderly patients

See section 3.

Caution should be exercised in patients over 65 years old, particularly those with severe heart or circulation diseases (such as arrhythmias or hypertension), as naphazoline may worsen these conditions.

Children

Do not use this medicine in children; the efficacy and safety have not been established in children.

Other medicines and COLIROFTA ANESTHETIC

Tell your doctor or pharmacist if you are using, have recently used, or might use any other medicines.

Especially consult your doctor if you are using:

  • Monoamine oxidase inhibitors (MAOIs) (you may suffer a severe hypertensive crisis).
  • Sulfonamides in eye drops or ointment for the eyes.
  • St. John's Wort.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

Do not use Colirofta Anesthetic during pregnancy.

The doctor should decide whether to interrupt breastfeeding or treatment after considering the benefit versus the possible risk.

Driving and using machines

You may notice that your vision becomes blurred or you experience other discomforts for a while after applying the eye drops. Do not drive or use machines until these effects have disappeared.

COLIROFTA ANESTHETIC contains phosphates

This medicine contains 5.8 mg of phosphates per ml.

If you have severe corneal damage (the transparent layer on the front of the eye), treatment with phosphates, in very rare cases, can cause blurred vision due to calcium accumulation.

3. How to use COLIROFTA ANESTHETIC

Follow the administration instructions for this medicine exactly as indicated by your doctor. If in doubt, consult your doctor or pharmacist again.

The recommended dose is:

Adults

Generally, instill 1 or 2 drops into the affected eye as needed.

Use in elderly patients

It is recommended to start treatment with the lowest recommended dose, as these patients may have a variable response to one of the components of the medicine, tetracaine.

Use in case of hepatic and/or renal insufficiency

The safety and efficacy have not been established in patients with hepatic and/or renal insufficiency.

Use in children

The safety and efficacy of this medicine have not been established in children.

Recommendations for use:

Ophthalmic route (in the eyes).

Sequence of three steps showing application of eye drops, person looking up and holding lower eyelid open

1 2 3

  1. Wash your hands.
  2. Take the bottle (dropper).
  3. After opening the bottle for the first time, remove the plastic ring from the seal if it is loose.
  4. Hold the bottle, upside down, between your fingers.
  5. Tilt your head back. Gently separate the eyelid from the eye with a finger until a pocket forms between the eyelid and your eye, where the drop should fall (figure 1).
  6. Bring the tip of the bottle close to the eye. You may find it helpful to use a mirror.
  7. Do not touch the eye or eyelid, or surrounding areas, with the dropper. The eye drops could become contaminated.
  8. Gently squeeze the base of the bottle to release one drop at a time (figure 2).
  9. After using this eye drop, press the edge of the eye next to the nose with your finger. This helps prevent the medicine from entering the rest of the body (figure 3).
  10. If you are applying drops to both eyes, repeat all the previous steps with the other eye.
  11. Close the bottle tightly immediately after using the medicine.

If a drop falls outsidethe eye, try again.

If you are using other ophthalmic medicines, wait at least 5 minutes between the administration of this eye drop and the other ophthalmic medicines. Ophthalmic ointments should be administered last.

If you use more COLIROFTA ANESTHETIC than you should

Taking a considerably larger dose of Colirofta Anesthetic than the recommended dose, for example, if you accidentally swallow Colirofta Anesthetic, may cause serious side effects that affect the heart and circulation. The symptoms may include: decreased heart rate (bradycardia), severe headache, nausea, vomiting, respiratory problems, increased heart rate (tachycardia), and chest pain.

An overdose in the eyes can be eliminated by rinsing the eyes with lukewarm water. Do not apply more drops until the next dose.

In case of severe overdose or accidental ingestion, consult your doctor or pharmacist immediately or the Toxicology Information Service, phone 91 562 04 20, indicating the medicine and the amount used.

Severe reactions such as a drop in body temperature, drowsiness, or other symptoms of central nervous system depression (especially in children) and severe reactions that affect the cardiovascular system may occur.

After ingestion, especially by children, symptoms such as nausea, vomiting, lethargy, palpitations, difficulty breathing, among others, may appear.

If you forget to use COLIROFTA ANESTHETIC

Do not use a double dose to make up for forgotten doses.

Apply a single dose as soon as you remember. However, if it is almost time for the next dose, continue with the next dose of your regular schedule.

If you have any other questions about the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everyone gets them.

The following side effects have been reported, whose frequency is not known:

Due to the anesthetic, excessive use of this medicine may cause corneal ulcers or eye damage.

Rarely, allergic reactions may occur.

Due to the presence of naphazoline in the medicine, you may experience increased pupil size and increased pressure in the eye. General side effects such as headache, increased blood pressure, heart rate, and irregular heartbeat, increased heart rate, nausea, fainting, and stroke may occur.

Other side effects in children

Excessive use of naphazoline in infants and young children may cause central nervous system depression and a significant decrease in body temperature.

Rarely, itching has been observed after application.

Continuous redness and eye irritation, conjunctivitis, and eye pain have also been reported.

In predisposed patients, in general, and with greater use and frequency than recommended, tremors, weakness, and sweating may occur.

Reporting side effects

If you experience any side effects, consult your doctor or pharmacist, even if they are not listed in this leaflet. You can also report them directly through the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaRAM.es.By reporting side effects, you can contribute to providing more information on the safety of this medicine.

5. Conservation of COLIROFTA ANESTHETIC

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiration date stated on the packaging and carton after EXP. The expiration date is the last day of the month indicated.

Before the first opening, store in the refrigerator (between 2°C and 8°C). Once opened, do not store above 25°C.

To avoid infections, discard the bottle 4 weeks after first opening.

Write the opening date of the bottle in the space provided on the carton.

Medicines should not be disposed of via wastewater or household waste. Deposit the packaging and any unused medicines in the SIGRE collection point at the pharmacy. If in doubt, ask your pharmacist how to dispose of the packaging and any unused medicines. This will help protect the environment.

6. Package contents and additional information

Composition of COLIROFTA ANESTHETIC

  • The active ingredients are tetracaine hydrochloride and naphazoline hydrochloride. Each ml of eye drops solution contains 5 mg of tetracaine hydrochloride (0.5%) and 0.5 mg of naphazoline hydrochloride (0.05%).
  • The other ingredients are chlorobutanol, monosodium phosphate monohydrate, disodium phosphate dodecahydrate, sodium chloride, and purified water.

Appearance of the product and package contents

Colirofta Anesthetic is an eye drop solution; clear and colorless liquid.

It is presented in a carton containing a dropper bottle (10 ml plastic bottle).

Marketing authorization holder and manufacturer

Marketing authorization holder

Alcon Healthcare, S.A.

World Trade Center Almeda Park

Plaça de la Pau s/n, Edificio 6, planta 3

08940 – Cornellà de Llobregat (Barcelona)

Spain

Manufacturer

Siegfried El Masnou, S.A.

C/ Camil Fabra, 58

08320 – El Masnou (Barcelona)

Spain

or

Alcon Laboratories Belgium

Lichterveld 3

2870 Puurs-Sint-Amands

Belgium

Date of the last revision of this leaflet: June 2025

Detailed information about this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

About the medicine

How much does COLIROFTA ANESTHETIC 5 mg/ml + 0.5 mg/ml EYE DROPS SOLUTION cost in Spain ( 2025)?

The average price of COLIROFTA ANESTHETIC 5 mg/ml + 0.5 mg/ml EYE DROPS SOLUTION in December, 2025 is around 3.39 EUR. Prices may vary depending on the region, pharmacy, and whether a prescription is required. Always check with a local pharmacy or online source for the most accurate information.

Online doctors for COLIROFTA ANESTHETIC 5 mg/ml + 0.5 mg/ml EYE DROPS SOLUTION

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for COLIROFTA ANESTHETIC 5 mg/ml + 0.5 mg/ml EYE DROPS SOLUTION – subject to medical assessment and local rules.

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Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Dr. Ben Harbi offers reliable, accessible medical support through online consultations, helping patients make informed decisions about their health with a clear, structured, and compassionate approach.

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Patients commonly seek her help for:

  • High blood pressure, headaches, dizziness, swelling, palpitations.
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