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SEKISAN 3.54 mg/ml SYRUP

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About the medicine

How to use SEKISAN 3.54 mg/ml SYRUP

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Leaflet: information for the patient

Sekisan 3.54 mg/ml syrup

cloperastine fendizoate

Read this leaflet carefully before starting to take this medicine, as it contains important information for you.

Follow the administration instructions of the medicine contained in this leaflet or as indicated by your doctor or pharmacist.

  • Keep this leaflet, as you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience side effects, consult your doctor or pharmacist, even if they are not listed in this leaflet. See section 4.
  • You should consult a doctor if it worsens or does not improve after 7 days.

Contents of the leaflet:

  1. What Sekisan is and what it is used for
  2. What you need to know before taking Sekisan
  3. How to take Sekisan
  4. Possible side effects

5 Conservation of Sekisan

  1. Package contents and additional information

1. What Sekisan is and what it is used for

Cloperastine, the active ingredient of this medicine, is a cough suppressant that inhibits the cough reflex. Sekisan is a medicine indicated for the treatment of non-productive forms of cough, such as irritative cough or nervous cough for adults and children from 2 years old.

You should consult a doctor if it worsens or does not improve after 7 days of treatment.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before taking Sekisan

Do not take Sekisanif:

  • You are allergic (hypersensitive) to the active ingredient or to any of the other components of this medicine (listed in section 6).
  • You are allergic to allergy medicines (antihistamines).
  • You are taking medicines for the treatment of depression.
  • You are pregnant or think you may be pregnant or are breastfeeding.
  • Children under 2 years old cannot take this medicine.

Warnings and precautions

Consult your doctor or pharmacist before starting to take Sekisan:

  • If you have high intraocular pressure.
  • If you have been told you have prostate hypertrophy.
  • If you have difficulty urinating.
  • If you are hypertensive.
  • If you have heart problems.
  • If you have a degenerative muscle disease called myasthenia gravis.
  • If you have any type of gastric or intestinal obstruction, including ulcers.
  • If you have chronic cough due to smoking, lung problems, or asthma.
  • If the cough persists after 7 days of treatment.

Children

Children under 2 years old cannot take this medicine, it is contraindicated.

Other medicines and Sekisan

Tell your doctor or pharmacist if you are taking, have recently taken, or may need to take any other medicine.

Sekisan may interact with other medicines such as:

  • Medicines to help you sleep (sedatives, opioid analgesics, barbiturics, hypnotics, or benzodiazepines).
  • Medicines for depression and medicines for the treatment of Parkinson's disease because they may potentiate the adverse effects of this medicine.
  • Expectorant and mucolytic medicines used to eliminate excess mucus and phlegm, because taking them at the same time as a cough medicine like Sekisan may prevent the elimination of excess mucus and produce choking.

Taking Sekisan with food, drinks, and alcohol

During treatment with Sekisan, do not drink alcohol as it may increase the effects of alcohol.

Taking this medicine with food and drinks does not affect its efficacy.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

It is contraindicated in pregnancy and breastfeeding.

Driving and using machines

Sekisan may cause drowsiness at usual doses. If so, refrain from driving and operating hazardous machinery.

Sekisan contains sucrose, propyl hydroxybenzoate (E-216), methyl hydroxybenzoate (E-218), propylene glycol (E-1520), ethanol, and sodium

This medicine contains sucrose. If your doctor has told you that you have an intolerance to certain sugars, consult with them before taking this medicine.

Patients with diabetes mellitus should note that this medicine contains 4.5 g of sucrose per 10 ml dose.

It may cause allergic reactions (possibly delayed) because it contains methyl hydroxybenzoate (E-218) and propyl hydroxybenzoate (E-216).

This medicine contains 26.25 mg of propylene glycol (E-1520) in each unit dose (10 ml), equivalent to 2.625 mg/ml.

This medicine contains 3.3 mg of alcohol (ethanol) in each unit dose (10 ml), equivalent to 0.33 mg/ml (0.033% p/v). The amount in 10 ml (unit dose) of this medicine is equivalent to less than 0.083 ml of beer or 0.034 ml of wine.

The small amount of alcohol in this medicine does not produce any noticeable effect.

This medicine contains less than 23 mg of sodium (1 mmol) per 10 ml; it is essentially "sodium-free".

3. How to take Sekisan

Follow the administration instructions of the medicine contained in this leaflet or as indicated by your doctor or pharmacist. In case of doubt, ask your doctor or pharmacist.

The recommended dose is:

In adults and adolescents over 12 years old: 10 ml, 3 times a day.

In children:Between 7 and 12 years old: 5 ml, 2 times a day.

Between 5 and 6 years old: 3 ml, 2 times a day.

Between 2 and 4 years old: 2 ml, 2 times a day.

Sekisan is contraindicated in children under 2 years old.

Shake the bottle before use.

This medicine is taken orally.

Measure the amount of medicine to be taken with the measuring cup included in the package.

If you take more Sekisan than you should

The symptoms of overdose are: excitement and difficulty breathing.

If you have taken more Sekisan than you should, consult your doctor or pharmacist immediately or call the poison control center at 91 562 04 20, indicating the medicine and the amount taken.

If you forget to take Sekisan

Do not take a double dose to make up for forgotten doses.

This treatment is symptomatic; if you do not have a cough, do not take it, and if it returns, take the medicine as indicated in section 3. How to take Sekisan.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, Sekisan can cause side effects, although not everyone gets them.

The most common side effects, although rare, are: drowsiness and dry mouth.

Side effects that may occur are:

Uncommon (may affect up to 1 in 100 patients): drowsiness, dry mouth (at high doses), movement disorders, tremors, and dizziness.

Very rare (may affect up to 1 in 10,000 patients): allergic reaction, urticaria.

Reporting side effects

If you experience any side effects, consult your doctor or pharmacist, even if they are not listed in this leaflet. You can also report them directly through the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Conservation of Sekisan

This medicine does not require special storage conditions.

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiration date stated on the package after CAD. The expiration date is the last day of the month indicated.

Medicines should not be disposed of through wastewater or household waste. Deposit the packages and medicines you no longer need at the SIGRE point in your pharmacy. If in doubt, ask your pharmacist how to dispose of packages and medicines you no longer need. This will help protect the environment.

6. Package contents and additional information

Composition of Sekisan

The active ingredient of Sekisan is Cloperastine fendizoate. Each ml of syrup contains 3.54 mg of cloperastine fendizoate (equivalent to 2 mg of cloperastine hydrochloride).

The other components (excipients) are: sucrose, microcrystalline cellulose-carboxymethylcellulose sodium, macrogol 2000 monoester, methyl hydroxybenzoate (E-218), propyl hydroxybenzoate (E-216), banana essence (contains propylene glycol (E-1520) and ethanol), and purified water.

Appearance of the product and package contents

Sekisan is presented as a white syrup with a characteristic banana essence odor. It is presented in a 120 and 200 ml amber PET bottle with a child-resistant closure. The package includes a graduated measuring cup with several measurements.

Marketing authorization holder and manufacturer

Marketing authorization holder:

Almirall, S.A. General Mitre, 151 08022 – Barcelona (Spain).

Manufacturer:

Industrias Farmacéuticas Almirall, S.A.

Ctra. de Martorell, 41-61 08740 Sant Andreu de la Barca - Barcelona (Spain).

Local representative:

Laboratorios ERN, S.A.

C/Perú, 228

08020 Barcelona, Spain

Date of the last revision of this leaflet:June 2014

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/.

Online doctors for SEKISAN 3.54 mg/ml SYRUP

Discuss questions about SEKISAN 3.54 mg/ml SYRUP, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

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Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

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Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

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Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
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  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Joao Silva

General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

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Bulat Garipov

General medicine 15 years exp.

Dr. Bulat Garipov is a radiologist with more than 15 years of experience, specializing in magnetic resonance imaging (MRI). Throughout his professional career, he has worked in leading diagnostic imaging centers, both in on-site practice and teleradiology, which has allowed him to develop a broad and versatile approach to radiology.

Over the years, he has gained solid experience in interpreting MRI studies in various areas, including:

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You could consult Dr. Bulat Garipov in cases where accurate interpretation of MRI studies or a second expert opinion is required. His expertise is especially valuable in cases of suspected neurological conditions, back and joint pain, vascular disorders, as well as in the diagnosis of abdominal and pelvic diseases. The doctor also provides support in complex or unclear clinical situations, including the review of previously performed studies, which helps improve diagnostic accuracy and determine the optimal treatment strategy. A teleradiology format is available, allowing you to receive a professional opinion remotely.

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Frequently Asked Questions

Is a prescription required for SEKISAN 3.54 mg/ml SYRUP?
SEKISAN 3.54 mg/ml SYRUP does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in SEKISAN 3.54 mg/ml SYRUP?
The active ingredient in SEKISAN 3.54 mg/ml SYRUP is cloperastine. This information helps identify medicines with the same composition but different brand names.
Who manufactures SEKISAN 3.54 mg/ml SYRUP?
SEKISAN 3.54 mg/ml SYRUP is manufactured by Almirall S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of SEKISAN 3.54 mg/ml SYRUP online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether SEKISAN 3.54 mg/ml SYRUP is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to SEKISAN 3.54 mg/ml SYRUP?
Other medicines with the same active substance (cloperastine) include CINFATUSINA 3.54 mg/ml ORAL SUSPENSION, CLOPERASTINE KERN PHARMA 3.54 mg/ml SYRUP, CLOPERASTINE NORMON 3.54 mg/ml ORAL SUSPENSION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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