Bg pattern

PULMOPRODIFF 0.25%/18% MEDICINAL GAS

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use PULMOPRODIFF 0.25%/18% MEDICINAL GAS

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

Show original

Introduction

Package Leaflet: Information for the User

PulmoProDiff 0.25%/ 18% compressed medical gas

carbon monoxide (CO)/helium (He)

Read this package leaflet carefully before starting to use this medicine, as it contains important information for you.

  • Keep this package leaflet, as you may need to read it again.
  • If you have any questions, ask your doctor or nurse.
  • If you experience side effects, consult your doctor, even if they are side effects not listed in this package leaflet. See section 4.

Contents of the Package Leaflet

  1. What PulmoProDiff is and what it is used for
  2. What you need to know before starting to use PulmoProDiff
  3. How to use PulmoProDiff
  4. Possible side effects
  5. Storage of PulmoProDiff
  6. Contents of the pack and further information

1. What PulmoProDiff is and what it is used for

PulmoProDiff is a medical gas for exclusive use in the diagnosis of lung function. It is used during diagnostic tests of lung function: determination of diffusion capacity/transfer factor and lung volume.

The medical gas PulmoProDiff can only be used in patients who are able to perform the test, regardless of their age.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before starting to use PulmoProDiff

Do not use this medical gas:

Unless your doctor has asked you to undergo respiratory function tests.

Warnings and precautions

Consult your doctor before starting to use PulmoProDiff.

If you have a history of coronary artery disease, you may be at risk of myocardial ischemia caused by carbon monoxide, as indicated by changes in the ECG (ST segment descent).

Children

This medical gas should be used with caution in children due to the lack of data on the systemic toxicity of this mixture.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor before using this medical gas.

Driving and using machines

The use of this medical gas during respiratory function tests does not affect the ability to drive and use machines.

3. How to use PulmoProDiff

PulmoProDiff can only be used for respiratory function tests by inhalation and exactly as your doctor or the responsible medical staff has indicated. If you have any doubts, consult your doctor or the medical staff attending you.

Only the doctor or the responsible medical staff should decide the duration of the respiratory function test and the frequency of repetition of the test.

Safety instructions

Smoking or lighting open flames is not allowed in the room where the medical gas is being used.

If you have any doubts about the use of this medicine, consult your doctor or the medical staff attending you.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

During inhalation of this medical gas during respiratory function tests, very unlikely side effects such as dizziness, chest pain, and disorientation may occur. If any symptoms of this nature occur during the use of the medical gas, inhalation should be stopped immediately and medical treatment should be administered.

Reporting of side effects

If you experience any side effects, consult your doctor, pharmacist, or nurse, even if they are possible side effects not listed in this package leaflet. You can also report them directly through the Spanish Pharmacovigilance System for Human Use Medicines: www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of PulmoProDiff

Keep this medical gas out of the sight and reach of children.

Do not use this medical gas after the expiration date shown on the gas cylinder after CAD.

Do not dispose of the container of this medical gas; return it to the supplier.

These measures will help protect the environment.

Store below 50 °C.

All regulations regarding the handling of pressure vessels must be followed.

Store in the original gas cylinder. Do not transfer the contents of the original gas cylinder to another gas cylinder.

Store gas cylinders indoors, in well-ventilated rooms or outdoors under cover and protected from adverse weather conditions.

Protect gas cylinders from impacts, falls, oxidizing and flammable materials, humidity, heat sources, or ignition.

Different types of medical gas should be separated from each other. Full and empty gas cylinders should be stored separately.

6. Contents of the pack and further information

Composition of PulmoProDiff

  • The active ingredients are carbon monoxide and helium.
  • The other components are nitrogen and oxygen.

Appearance of the product and contents of the pack

PulmoProDiff is a colorless, odorless, and tasteless compressed medical gas.

10-liter aluminum gas cylinder (identified with a bright green tip and white body) filled to a pressure of 150 bar, equipped with a residual pressure valve made of copper with a specific outlet connection.

Marketing authorization holder and manufacturer

Marketing authorization holder

Messer Ibérica de Gases S.A.U.

Autovía Tarragona-Salou, km. 3.8

E-43480, Vilaseca (Tarragona)

Spain

Manufacturer

Messer Austria GmbH

Industriestraße 5

2352 Gumpoldskirchen

Austria

This medicine is authorized in the EEA member states under the following names:

PulmoProDiff Netherlands, Austria, Germany, Poland, Romania, and Spain

Zyplorin: Czech Republic

Date of the last revision of this package leaflet:

May 2023

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) (http://www.aemps.gob.es/

Online doctors for PULMOPRODIFF 0.25%/18% MEDICINAL GAS

Discuss questions about PULMOPRODIFF 0.25%/18% MEDICINAL GAS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (2)
Doctor

Svetlana Kolomeeva

Cardiology 18 years exp.

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

  • High blood pressure, headaches, dizziness, swelling, palpitations.
  • Diagnosis and management of hypertension, arrhythmias, and tachycardia.
  • Metabolic syndrome, excess weight, high cholesterol.
  • Chronic fatigue, insomnia, poor concentration, anxiety.
  • Respiratory symptoms: colds, flu, sore throat, cough, fever.
  • Digestive issues: heartburn, bloating, constipation, IBS symptoms.
  • Chronic conditions: diabetes, thyroid disorders.
  • Interpretation of lab tests and medical reports, therapy adjustment.
  • Second opinion and decision-making support.
  • Cardiovascular disease prevention and metabolic risk reduction.
  • Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

Camera Book a video appointment
€55
5.0 (77)
Doctor

Sergey Ilyasov

Psychiatry 7 years exp.

Dr Sergey Ilyasov is an experienced neurologist and qualified psychiatrist who provides online consultations for adults and adolescents. Combining deep neurological expertise with a modern psychiatric approach, he ensures comprehensive diagnostics and effective treatment for a wide range of conditions affecting both physical and mental health.

Dr. Ilyasov helps patients in the following cases:

  • Chronic headaches (migraine, tension-type headache), back pain, neuropathic pain, dizziness, numbness in limbs, coordination disorders.
  • Anxiety disorders (panic attacks, generalized anxiety disorder), depression (including atypical and treatment-resistant forms), sleep disturbances (insomnia, hypersomnia, nightmares), stress, burnout.
  • Chronic pain syndromes and psychosomatic symptoms (e.g., irritable bowel syndrome related to stress, vegetative-vascular dystonia).
  • Behavioral disorders and concentration difficulties in adolescents (including ADHD, autism spectrum disorders), nervous tics.
  • Memory impairments, phobias, obsessive-compulsive disorder (OCD), emotional swings, and support for post-traumatic stress disorder (PTSD).

Thanks to his dual specialization in neurology and psychiatry, Dr Sergey Ilyasov offers integrated and evidence-based care for complex conditions requiring a multidisciplinary approach. His consultations focus on accurate diagnosis, development of an individualized treatment plan (including pharmacotherapy and psychotherapeutic methods), and long-term support adapted to each patient's unique needs.

Book an online consultation with Dr. Sergey Ilyasov to receive qualified assistance and improve your well-being today.

Camera Book a video appointment
€89
5.0 (137)
Doctor

Taisiia Proida

Psychiatry 7 years exp.

Dr. Taisiia Proida is a psychiatrist and cognitive behavioural therapist (CBT), and a member of the European Psychiatric Association. She offers online consultations for adults aged 18 and over, combining evidence-based medicine with an individualised approach to mental health care.

She specialises in consultations and ongoing support for a wide range of mental health concerns, including:

  • Mood disorders: depression, bipolar disorder, postpartum depression.
  • Anxiety disorders: generalised anxiety, OCD, panic attacks, phobias.
  • Post-traumatic stress disorder (PTSD) and complex PTSD.
  • Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). Assessment is provided only after an initial psychiatric evaluation and during a follow-up appointment.
  • Personality disorders and emotional instability.
  • Cyclothymia and mood fluctuations.
  • Schizophrenia spectrum and related conditions.

Dr. Proida combines clinical expertise with an empathetic approach, offering structured support based on evidence-based practices. Her work integrates CBT techniques with medical management, with a focus on anxiety and depressive disorders.

She works with clients from different countries and cultural backgrounds, adapting her communication style and recommendations to individual needs. With experience in international clinical trials (Pfizer, Merck), she values clarity, trust, and collaborative partnership in patient care.

Camera Book a video appointment
€120
5.0 (2)
Doctor

Alexander Nazarchuk

Allergology 7 years exp.

Dr. Alexander Nazarchuk is a physician specialising in allergology and internal medicine. He provides online consultations for adults, following the principles of evidence-based medicine — no outdated treatments or unnecessary tests, with clear explanations and a personalised approach. He helps patients with a wide range of allergic and therapeutic conditions, from common day-to-day complaints to complex cases involving allergies, gastrointestinal issues, cardiovascular concerns, respiratory symptoms, and more.

You can consult Dr. Nazarchuk for:

  • Test interpretation and guidance on diagnostic plans.
  • Allergic rhinitis, hay fever, bronchial asthma (including severe cases).
  • Food and drug allergies, skin rashes, angioedema.
  • Atopic dermatitis, urticaria, contact allergies.
  • Allergen-specific immunotherapy (AIT) – initiation and ongoing management.
  • Abdominal pain, bloating, changes in bowel habits, nausea, heartburn.
  • High blood pressure and adjustment of baseline antihypertensive therapy.
  • Hyperlipidaemia and elevated cholesterol.
  • Cough, nasal congestion, fever, sore throat.
  • Anaemia, including iron deficiency and related conditions.
  • Other issues related to allergology and internal medicine.

During consultations, Dr. Nazarchuk takes a thorough, structured approach — analysing symptoms, identifying potential causes, and helping patients make informed decisions. Whether treatment, further investigation, or monitoring is needed, he explains each step clearly so you understand your health and how best to manage it.

Camera Book a video appointment
€55

Frequently Asked Questions

Is a prescription required for PULMOPRODIFF 0.25%/18% MEDICINAL GAS?
PULMOPRODIFF 0.25%/18% MEDICINAL GAS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
Who manufactures PULMOPRODIFF 0.25%/18% MEDICINAL GAS?
PULMOPRODIFF 0.25%/18% MEDICINAL GAS is manufactured by Messer Iberica De Gases, S.A.U.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of PULMOPRODIFF 0.25%/18% MEDICINAL GAS online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether PULMOPRODIFF 0.25%/18% MEDICINAL GAS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to PULMOPRODIFF 0.25%/18% MEDICINAL GAS?
Other medicines with the same active substance () include MEDICAL AIR COMPRESSED GAS LINDE 200 BAR, COMPRESSED MEDICAL GAS, SYNTHETIC MEDICAL AIR METAL CARBIDES, 22% V/V, MEDICAL GAS, COMPRESSED, SYNTHETIC MEDICAL AIR NIPPON GASES 200 BAR, COMPRESSED MEDICAL GAS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
bg-pattern-dark

Stay informed about Oladoctor

News about new services, product updates and useful information for patients.

Follow us on social media