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NEUROMADE Hard Capsules

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use NEUROMADE Hard Capsules

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

PACKAGE LEAFLET: INFORMATION FOR THE USER

NEUROMADE hard capsules

Read the entire package leaflet carefully before starting to take the medicine.

  • Keep this package leaflet, as you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you. Do not pass it on to others, as it may harm them, even if their symptoms are the same as yours.
  • If you experience any side effects, consult your doctor or pharmacist. This includes any possible side effects not listed in this package leaflet.

Contents of the package leaflet:

  1. What Neuromade capsules are and what they are used for
  2. Before taking Neuromade capsules
  3. How to take Neuromade capsules
  4. Possible side effects
  5. Storage of Neuromade capsules
  6. Further information

1. What NEUROMADE CAPSULES are and what they are used for

Neuromade capsules are an association of the water-soluble vitamins of the B group: thiamine (vitamin B1), pyridoxine (vitamin B6), and cyanocobalamin (vitamin B12) for oral administration.

Vitamins are essential nutrients that are involved in numerous human metabolic processes.

Neuromade capsules are indicated in adults and patients over 14 years of age, in:

Treatment of states of deficiency of vitamins B1, B6, and B12, which could cause neuropathies (diseases of the peripheral nervous system) and could manifest in cases of back pain, such as lumbalgia. Convalescence. Insufficient diet.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. Before taking NEUROMADE CAPSULES

Do nottake NEUROMADE capsules

  • if you are allergic (hypersensitive) to the active substances, to cobalamins (e.g., hydroxocobalamin), to cobalt, or to any of the other components of the medicine (see section 6).
  • if you are being treated with levodopa (a medicine for Parkinson's disease).
  • if you have Leber's disease (hereditary optic nerve atrophy) or tobacco amblyopia (decreased visual acuity that can occur in people who abuse tobacco), as they may worsen.

Due to the doses of vitamins it contains, do not take this medicine:

  • if you are pregnant or breastfeeding.
  • children under 14 years of age.

Be careful with NEUROMADE capsules

  • Do not take a higher dose than recommended or for a longer period than recommended. When high doses of pyridoxine (vitamin B6) are administered continuously, adverse neurological effects (headache, tingling sensation, etc.) may occur. Cases of dependence and withdrawal have been reported when taking 200 mg of pyridoxine for a month.
  • As it contains vitamin B12, if you have a blood disease such as anemia, your doctor should check the cause before taking it.
  • If you are prone to gout, due to the content of vitamin B12, your doctor should perform a special clinical check, as it may worsen.
  • If you have kidney or liver disease, do not take this medicine, as the doses it contains exceed the recommended doses in these situations.
  • If you have conditions such as uremia (accumulation of urea in the blood), infections, iron or folic acid deficiency, or are being treated with medicines that have a suppressive effect on the bone marrow (e.g., chloramphenicol), the therapeutic response to vitamin B12 may decrease.
  • You should be careful with the sun or avoid exposure to it, as pyridoxine can cause photosensitivity with skin lesions.
  • If you have previously suffered from an allergy to vitamin B1 on skin contact (contact dermatitis) for professional reasons, you may experience a relapse when taking this medicine.
  • Interference with analytical tests: If you are going to undergo any diagnostic test (including blood tests, urine tests, skin tests that use allergens, etc.), inform your doctor that you are taking this medicine, as it may alter the results. In some determinations of urobilinogen, theophylline, and uric acid, false results may occur.

Use of other medicines

Tell your doctor or pharmacist if you are using or have recently used other medicines, including those obtained without a prescription.

Neuromade capsules may interact with the following medicines:

  • Levodopa (medicines for the treatment of Parkinson's disease).
  • Phenobarbital, phenytoin (medicines for epilepsy).
  • Amiodarone (for the heart).
  • Altretamine (for cancer treatment).
  • Neuromuscular blocking agents (used in anesthesia for surgery).
  • The following medicines may interfere with pyridoxine (vitamin B6) and may reduce its levels, including: antibiotics for tuberculosis (isoniazid, cycloserine, and ethionamide), penicillamine (for rheumatic diseases), hydralazine (for hypertension), immunosuppressants such as corticosteroids or cyclosporine and azathioprine (used in organ transplantation), cyclophosphamide (for cancer).
  • Several medicines can decrease the absorption of cyanocobalamin (vitamin B12) or reduce its effect, such as: ascorbic acid (vitamin C) in high doses, aminoglycoside antibiotics, colchicine (for gout treatment), H2 antagonists (medicines against stomach acid or stomach ulcers, such as ranitidine, cimetidine, etc.), aminosalicylic acid (for intestinal diseases), omeprazole (for stomach ulcers), medicines for epilepsy, metformin (for diabetes), chloramphenicol (antibiotic), sustained-release potassium preparations, or cobalt radiation.
  • Oral contraceptives may reduce the levels of both vitamin B6 and vitamin B12.

Taking NEUROMADE capsules with food and drinks

Alcoholic beverages decrease the effect of the vitamins.

Pregnancy and breastfeeding

Consult your doctor or pharmacist before using any medicine.

Due to the doses of vitamins B that this medicine contains, which are higher than those recommended during pregnancy and breastfeeding, it is contraindicated during these periods.

Thiamine, pyridoxine, and cyanocobalamin pass into breast milk.

Driving and using machines

This medicine may cause drowsiness in a few patients, who should not drive and/or use machines during treatment.

3. How to take NEUROMADE CAPSULES

Follow the administration instructions of Neuromade capsules indicated by your doctor.

Consult your doctor or pharmacist if you have any doubts.

The normal dose is:

It is recommended to take 1 capsule per day. In certain cases, the doctor may indicate taking 2 capsules per day.

Oral route.

The capsules are taken with the help of a sufficient amount of water.

In general, the treatment should not exceed 2 weeks, although the doctor may recommend administration for more than 15 days.

Use in children

This medicine is contraindicated in children under 14 years of age.

If you take more NEUROMADE capsules than you should

It is not expected that ingestion of high doses of Neuromade capsules will produce toxic effects.

If you have taken more Neuromade capsules than you should, you may experience symptoms such as: gastrointestinal disorders (diarrhea, nausea, and vomiting), nervous system disorders such as reduced sensitivity, tingling, numbness in feet and hands; you may also experience headache, increased sensitivity to sunlight with skin lesions; drowsiness, difficulty breathing, among other effects, depending on the dose. In rare cases, a severe allergic reaction (anaphylactic shock) may occur.

In children, accidental ingestion of very high doses of vitamin B6 may also cause deep sedation, weakness, and difficulty breathing.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or go to a medical center, or call the Toxicology Information Service, phone 91 562 04 20, indicating the medicine and the amount ingested.

If you forget to take NEUROMADE capsules

Do not take a double dose to make up for the forgotten doses.

If you have any further questions about the use of this product, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, Neuromade capsules can cause side effects, although not everyone gets them.

The assessment of side effects that may occur is based on the following frequencies:

uncommon (may affect between 1 and 10 in every 1,000 people).

Uncommonly, the following may appear: nausea, headache, effects on sensitivity (paresthesia) that manifest as a tingling sensation in arms and legs or alterations in touch, drowsiness, and skin rash (hypersensitivity reactions to vitamins B1, B6, and B12).

Other side effects that have been reported, with an unknown frequency, are: gastrointestinal disorders, diarrhea, photosensitivity with skin lesions such as blisters, dizziness, restlessness; disorder with reduced sensitivity and tingling, unsteady gait, numbness of feet or hands, which usually decrease when treatment is discontinued; a pyridoxine withdrawal syndrome more likely with higher doses and in treatments longer than a month; changes in urine color, swelling, and irritation in the eyes; occasionally anaphylactic reaction with itching, swelling, difficulty breathing, etc.; some cases of affection with nodules and pus on the face and neck.

If you experience any side effects, consult your doctor or pharmacist. This includes any possible side effects not listed in this package leaflet.

Reporting of side effects

If you experience any side effects, consult your doctor, pharmacist, or nurse, even if they are possible side effects not listed in this package leaflet. You can also report them directly through the Spanish Medicines Monitoring System for Human Use: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of NEUROMADE CAPSULES

Keep out of the reach and sight of children.

Do not use Neuromade capsules after the expiration date stated on the packaging after CAD. The expiration date is the last day of the month indicated.

No special storage conditions are required. Store in the original packaging.

Medicines should not be disposed of via wastewater or household waste. Place the packaging and any unused medicines in the SIGRE collection point at the pharmacy. If in doubt, ask your pharmacist how to dispose of the packaging and any unused medicines. This will help protect the environment.

6. Further information

Composition of NEUROMADE capsules

  • The active substances are: Thiamine hydrochloride (vitamin B1), Pyridoxine hydrochloride (vitamin B6), and Cyanocobalamin (Vitamin B12). Each capsule contains 50 mg of thiamine hydrochloride, 50 mg of pyridoxine hydrochloride, and 1,000 micrograms of cyanocobalamin.
  • The other components (excipients) are: Microcrystalline cellulose, silicon dioxide, and magnesium stearate.

Appearance of the product and packaging content

Neuromade capsules are presented in packages of 20 hard capsules.

Marketing authorization holder and manufacturer

TEOFARMA Srl

Via F.lli Cervi, 8

27010 Valle Salimbene (PV) – Italy

This package leaflet was approved in September 2011.

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for NEUROMADE Hard Capsules

Discuss questions about NEUROMADE Hard Capsules, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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€58
5.0 (44)
Doctor

Anastasiia Shalko

Family medicine 13 years exp.

Dr. Anastasiia Shalko is a general practitioner with a background in both paediatrics and general medicine. She graduated from Bogomolets National Medical University in Kyiv and completed her paediatric internship at the P.L. Shupyk National Medical Academy of Postgraduate Education. After working as a paediatrician in Kyiv, she relocated to Spain, where she has been practising general medicine since 2015, providing care for both adults and children.Her work focuses on urgent, short-term medical concerns – situations where patients need quick guidance, symptom assessment and clear next steps. She helps people understand whether their symptoms require in-person evaluation, home management or a change in treatment. Common reasons for booking an online consultation include:

  • acute respiratory symptoms (cough, sore throat, runny nose, fever)
  • viral illnesses such as colds and seasonal infections
  • gastrointestinal complaints (nausea, diarrhoea, abdominal pain, gastroenteritis)
  • sudden changes in how a child or adult feels
  • questions about existing treatment and whether adjustments are needed
  • renewal of prescriptions when clinically appropriate

Dr. Shalko works specifically with urgent and short-term problems, providing practical recommendations and helping patients determine the safest next step. She explains symptoms clearly, guides patients through decision-making and offers straightforward medical advice for everyday acute issues.She does not provide long-term management of chronic conditions, ongoing follow-up or comprehensive care plans for complex long-term illnesses. Her consultations are designed for acute symptoms, sudden concerns and situations where timely medical input is important.With clinical experience in both paediatrics and general medicine, Dr. Shalko confidently supports adults and children. Her communication style is clear, simple and reassuring, helping patients feel informed and supported throughout the consultation.

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€50
5.0 (5)
Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

Camera Book a video appointment
€80
5.0 (1038)
Doctor

Andrei Popov

General medicine 7 years exp.

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

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€80
0.0 (0)
Doctor

Joao Silva

General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

Camera Book a video appointment
€55

Frequently Asked Questions

Is a prescription required for NEUROMADE Hard Capsules?
NEUROMADE Hard Capsules requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in NEUROMADE Hard Capsules?
The active ingredient in NEUROMADE Hard Capsules is Vitamin B1 in combination with vitamin B6 and/or vitamin B12. This information helps identify medicines with the same composition but different brand names.
Who manufactures NEUROMADE Hard Capsules?
NEUROMADE Hard Capsules is manufactured by Teofarma S.R.L.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of NEUROMADE Hard Capsules online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether NEUROMADE Hard Capsules is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to NEUROMADE Hard Capsules?
Other medicines with the same active substance (Vitamin B1 in combination with vitamin B6 and/or vitamin B12) include BENEXOL B1-B6-B12 FILM-COATED TABLETS, HYDROXIL B1-B6-B12 FILM-COATED TABLETS, VITAGOBENS B1 B6 B12 FILM-COATED TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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