HIDROXIL 250 mg/250 mg /500 Micrograms Film-Coated Tablets

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Doctor
5.0(36)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

Book a video appointment
€86
This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use HYDROXIL B1-B6-B12 FILM-COATED TABLETS

Contents of the leaflet

  1. Introduction
  2. What Hidroxil is and what it is used for
  3. What you need to know before taking Hidroxil
  4. How to take Hidroxil
  5. Possible side effects
  6. Storage of Hidroxil
  7. Contents of the pack and further information

Introduction

Package Leaflet: Information for the User

Hidroxil B1-B6-B12film-coated tablets

thiamine hydrochloride / pyridoxine hydrochloride / cyanocobalamin

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

Follow exactly the administration instructions of the medicine contained in this leaflet or as indicated by your doctor or pharmacist.

  • Keep this leaflet, as you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience side effects, consult your doctor or pharmacist, even if it is a side effect not listed in this leaflet. See section 4.
  • You should consult a doctor if it worsens or does not improve after 7 days.

Contents of the Package Leaflet

  1. What Hidroxil is and what it is used for.
  2. What you need to know before taking Hidroxil.
  3. How to take Hidroxil.
  4. Possible side effects.
  5. Storage of Hidroxil.
  1. Contents of the pack and further information.

1. What Hidroxil is and what it is used for

The active ingredients of Hidroxil are the water-soluble vitamins B1 (thiamine), B6 (pyridoxine), and B12 (cyanocobalamin) that are involved in numerous human metabolic processes.

Hidroxil is indicated in: Prevention and treatment of deficiency of vitamins B1, B6, and B12, due to increased needs, reduced consumption, or absorption, which could manifest as symptoms of back pain, in convalescences, or insufficient diets.

Hidroxil B1-B6-B12 film-coated tablets are indicated in adults and adolescents over 14 years of age.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before taking Hidroxil

Do not take Hidroxil:

  • If you are allergic to vitamin B1, B6, or the various forms of vitamin B12, cobalt, or any of the other components of this medicine (listed in section 6).
  • If you are being treated with levodopa (a medicine for Parkinson's disease).
  • If you have Leber's disease (hereditary optic nerve atrophy) or tobacco amblyopia (decreased visual acuity that can occur in people who abuse tobacco), as they may worsen.

Due to the doses it contains, do not take this medicine:

  • If you have kidney or liver disease.
  • If you are pregnant or breastfeeding.
  • Children under 14 years of age.

Warnings and precautions

Consult your doctor or pharmacist before starting to take Hidroxil.

  • Do not take a higher dose than recommended or for a longer period than recommended.
  • If you have a blood disease, such as anemia, your doctor should check the cause before taking vitamin B12.
  • There have been cases of dependence and withdrawal when taking pyridoxine (vitamin B6) for a month, even at doses lower than those contained in this medicine.
  • You should avoid exposure to the sun due to a possible risk of photosensitivity (with skin lesions such as rash or blisters).
  • If you have previously had an allergy to vitamin B1 through skin contact (contact dermatitis) for professional reasons, you may experience a relapse when taking this medicine.

Interference with analytical tests

If you are going to undergo any diagnostic test (including blood tests, urine tests, skin tests that use allergens, etc.), inform your doctor that you are taking this medicine, as it may alter the results. In some determinations of urobilinogen, theophylline, uric acid, or antibodies against intrinsic factor (IF), false results may occur.

Children

This medicine is contraindicated in children under 14 years of age.

Other medicines and Hidroxil

Inform your doctor or pharmacist if you are using, have recently used, or may need to use any other medicine.

This medicine may interact with the following medicines:

  • Levodopa (a medicine for the treatment of Parkinson's disease).
  • Phenobarbital, phenytoin (for the treatment of epilepsy).
  • Altretamine (for the treatment of cancer).
  • Amiodarone (for the heart).
  • Neuromuscular blocking agents (used in anesthesia for surgery).
  • 5-Fluorouracil (for some types of cancer).
  • Several medicines can interfere with pyridoxine (vitamin B6) and may reduce its levels, including: antibiotics for the treatment of tuberculosis (isoniazid, cycloserine, ethionamide, and pyrazinamide), penicillamine (for rheumatic diseases), hydralazine (for high blood pressure), immunosuppressants such as corticosteroids, cyclosporine (used in organ transplantation, among other diseases).
  • Several medicines can decrease the absorption of vitamin B12 or reduce its effect, such as: high doses of ascorbic acid, antibiotics such as neomycin and chloramphenicol, colchicine (for the treatment of gout), H2 antagonists (medicines against acidity or stomach ulcers), aminosalicylic acid in long-term treatments (for intestinal diseases), omeprazole (for stomach ulcers), medicines for epilepsy, metformin (for diabetes), high doses of folic acid.
  • Oral contraceptives may reduce the levels of vitamins B6 and B12.

Taking Hidroxil with alcohol

Excessive alcohol consumption reduces the absorption of vitamins.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

Due to the doses of vitamins B contained in Hidroxil, which are much higher than those recommended during pregnancy and breastfeeding, this medicine is contraindicated during pregnancy and breastfeeding.

Hidroxil is not recommended in women of childbearing age who do not use an effective contraceptive method.

Driving and using machines

The influence of Hidroxil on the ability to drive and use machines is negligible or nonexistent. This medicine can cause drowsiness in a few patients, who should not drive and/or operate hazardous machinery during treatment.

Hidroxil contains sodium

This medicine contains less than 23 mg of sodium (1 mmol) per tablet; it is essentially "sodium-free".

3. How to take Hidroxil

Follow exactly the administration instructions of the medicine contained in this leaflet or as indicated by your doctor or pharmacist. In case of doubt, ask your doctor or pharmacist.

The recommended dose is:

Adults and adolescents over 14 years of age

1 tablet per day

In general, treatment should not exceed 15 days, although your doctor may recommend administration for a longer period.

If it worsens or does not improve after 7 days of treatment, you should consult your doctor.

Oral route.

It is preferable to swallow the tablets whole, with enough water.

Patient with hepatic or renal insufficiency

These patients should not take Hidroxil (see section 2).

Use in children

This medicine is contraindicated in children under 14 years of age (see section 2).

If you take more Hidroxil than you should

If you have taken more Hidroxil than you should, you may experience symptoms such as: gastrointestinal disorders (diarrhea, nausea, vomiting) and headache. Due to the content of pyridoxine, you may experience nervous disorders such as altered or reduced sensitivity, paresthesia, numbness in hands and feet, unsteady gait, etc.; you may also experience photosensitivity with skin lesions such as blisters; drowsiness, lethargy, difficulty breathing, among other effects, depending on the dose, increased serum concentrations of AST (SGOT) (a transaminase) and decreased serum concentrations of folic acid. In rare cases, a severe allergic reaction (anaphylactic shock) may occur.

In children, accidental ingestion of very high doses of vitamin B6 can also cause deep sedation, weakness, and difficulty breathing.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately, go to a medical center, or call the Toxicology Information Service, phone: 915 62 04 20, indicating the medicine and the amount taken.

If you forget to take Hidroxil

Do not take a double dose to make up for forgotten doses.

If you have any other doubts about the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

The assessment of side effects that can occur is based on the following frequencies: very common (may affect more than 1 in 10 people), common (may affect up to 1 in 10 people), uncommon (may affect up to 1 in 100 people), rare (may affect up to 1 in 1,000 people), and very rare (may affect up to 1 in 10,000 people).

Uncommonly, the following may appear: nausea, vomiting, headache, drowsiness, paresthesia (tingling sensation in arms and legs), and skin rash (redness or swelling). Allergic reactions (hypersensitivity reactions) to vitamins B1, B6, and B12 have also been described.

Other side effects that have been reported, with an unknown frequency, are: gastrointestinal disorders, diarrhea, loss of appetite (with high doses), photosensitivity with skin lesions such as blisters; very occasionally, a decrease in the number of platelets (thrombocytopenia); dizziness, restlessness, insomnia; disorders with reduced sensitivity and paresthesia, among other symptoms, which usually decrease when treatment is discontinued; changes in urine color, occasionally anaphylactic reaction with itching, difficulty breathing; vitamin B1 can rarely cause delayed hypersensitivity.

If an allergic reaction occurs, treatment should be discontinued and your doctor consulted immediately to apply appropriate treatment.

Reporting of side effects

If you experience any side effects, consult your doctor or pharmacist, even if it is a possible side effect not listed in this leaflet. You can also report them directly through the Spanish Medicines Monitoring System: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Hidroxil

Store below 25°C.

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date stated on the packaging after CAD. The expiry date is the last day of the month indicated.

Medicines should not be disposed of via wastewater or household waste. Return the packaging and any unused medicine to a pharmacy. If in doubt, ask your pharmacist how to dispose of the packaging and any unused medicine. This will help protect the environment.

6. Contents of the pack and further information

Composition of Hidroxil B1-B6-B12film-coated tablets

  • The active ingredients are thiamine hydrochloride (vitamin B1), pyridoxine hydrochloride (vitamin B6), and cyanocobalamin (vitamin B12).

Each tablet contains 250 mg of thiamine hydrochloride, 250 mg of pyridoxine hydrochloride, and 500 micrograms of cyanocobalamin.

  • The other ingredients (excipients) are: copovidone, sodium carboxymethyl starch (potato), sodium stearyl fumarate, modified cornstarch, citric acid, trisodium citrate, silicon dioxide, hypromellose, titanium dioxide (E-171), natural wax, glycerol, medium-chain triglycerides, and carmine (E-120).

Appearance of the product and contents of the pack

This medicine is presented in the form of pink, biconvex, elliptical film-coated tablets.

Packs of 15 and 30 tablets.

Marketing authorization holder and manufacturer

Marketing authorization holder

Almirall, S.A.

General Mitre, 151

08022 – Barcelona (Spain)

Manufacturer

Industrias Farmacéuticas Almirall, S.A.

Ctra. de Martorell, 41-61

08740 - Sant Andreu de la Barca (Barcelona) (Spain)

Date of the last revision of this leaflet:January 2022.

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) (http://www.aemps.gob.es/)

Online doctors for HYDROXIL B1-B6-B12 FILM-COATED TABLETS

Discuss questions about HYDROXIL B1-B6-B12 FILM-COATED TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(36)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

Book a video appointment
€86
Doctor
5.0(12)

Yevgen Yakovenko

Family medicine12 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment
€72
Doctor
5.0(3)

Lina Travkina

Family medicine13 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
  • Structured support for undiagnosed complaints.
  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Book a video appointment
€75
Doctor
5.0(19)

Nuno Tavares Lopes

Family medicineGeneral medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Book a video appointment
€70

Get HYDROXIL B1-B6-B12 FILM-COATED TABLETS Prescription Online

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Frequently Asked Questions

Is a prescription required for HYDROXIL B1-B6-B12 FILM-COATED TABLETS?

HYDROXIL B1-B6-B12 FILM-COATED TABLETS does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in HYDROXIL B1-B6-B12 FILM-COATED TABLETS?

The active ingredient in HYDROXIL B1-B6-B12 FILM-COATED TABLETS is Vitamin B1 in combination with vitamin B6 and/or vitamin B12. This information helps identify medicines with the same composition but different brand names.

Who manufactures HYDROXIL B1-B6-B12 FILM-COATED TABLETS?

HYDROXIL B1-B6-B12 FILM-COATED TABLETS is manufactured by Almirall S.A.. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of HYDROXIL B1-B6-B12 FILM-COATED TABLETS online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether HYDROXIL B1-B6-B12 FILM-COATED TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy HYDROXIL B1-B6-B12 FILM-COATED TABLETS in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy HYDROXIL B1-B6-B12 FILM-COATED TABLETS in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to HYDROXIL B1-B6-B12 FILM-COATED TABLETS?

Other medicines with the same active substance (Vitamin B1 in combination with vitamin B6 and/or vitamin B12) include BENEXOL B1-B6-B12 FILM-COATED TABLETS, NEUROMADE Hard Capsules, VITAGOBENS B1 B6 B12 FILM-COATED TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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