Bg pattern

NATIFAR 200/400/2 micrograms TABLETS

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use NATIFAR 200/400/2 micrograms TABLETS

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

Show original

Introduction

Package Leaflet: Information for the User

NATIFAR 200/400/2 micrograms tablets

Iodine/ folic acid/ vitamin B12

Read this package leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this package leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this package leaflet. See section 4.

Contents of the package leaflet

  1. What is NATIFAR and what is it used for
  2. What you need to know before you take NATIFAR
  3. How to take NATIFAR
  4. Possible side effects
  5. Storage of NATIFAR
  6. Contents of the pack and further information

1. What is NATIFAR and what is it used for

It contains as active substances iodine (as potassium iodide) and two substances belonging to the group of B vitamins, folic acid and cyanocobalamin (vitamin B12).

Natifar is indicated for the prevention of disorders due to iodine, folic acid, and vitamin B12 deficiency in women who are planning a pregnancy, for one month before conception and, at medical discretion, during the first trimester of pregnancy, as prophylaxis for developmental deficiencies of the nervous system in the fetus (neural tube defects and neurological disorders).

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you take NATIFAR

Do not take NATIFAR

  • if you are allergic to iodine (or potassium iodide), folic acid, vitamin B12, cobalt, or any of the other ingredients of this medicine (listed in section 6).
  • if you have goiter (enlargement of the thyroid gland).

Warnings and precautions

Consult your doctor or pharmacist before starting to take Natifar.

Because this medicine contains potassium iodide and some people are particularly sensitive to iodine, treatment should be started with caution.

Caution should be exercised if you have acute bronchitis, overt or latent hyperthyroidism, Addison's disease (hormonal deficiency caused by damage to the adrenal gland), dehydration, or autoimmune thyroid disease.

If you suffer from any of the following diseases: chronic urticaria (skin disease that produces skin rashes in the form of hives or wheals), systemic lupus erythematosus (autoimmune disease that can affect many organs), or hypocomplementemic vasculitis (skin lesions similar to urticaria produced by inflammation of blood vessels), inform your doctor before taking this medicine, as it may cause you significant side effects.

Treatment with Natifar in epileptic patients should be done under strict medical supervision.

Special caution should be exercised when starting treatment in patients with kidney disease, hyperkalemia (high potassium levels), or active tuberculosis.

Iodinated disinfectants should not be used for the disinfection of the newborn or the pregnant mother.

Interference with analytical tests

If you are going to undergo any diagnostic test (including blood tests, urine tests, skin tests that use allergens, etc.), inform your doctor that you are taking this medicine, as it may alter the results. This medicine may affect thyroid function tests.

Children and adolescents

This medicine is not indicated for children under 14 years of age.

Taking NATIFAR with other medicines

Tell your doctor or pharmacist if you are using, have recently used, or might use any other medicine.

Certain medicines may interfere with Natifar. In these cases, it may be necessary to change the dose, interrupt treatment with one of them, or wait at least 3 hours between administration of both.

It is important that you inform your doctor if you are taking or have recently taken any of the following medicines:

  • Anti-ulcer medicines such as omeprazole (medicines for gastric acidity)
  • Chloramphenicol (antibiotic)
  • Phenytoin, phenobarbital, barbiturates (medicine for convulsions)
  • Methotrexate (medicine for cancer or autoimmune diseases)
  • Nitrofurantoin (medicine for urinary infections)
  • Primidone (medicine for epilepsy)
  • Pyrimethamine (medicine for the treatment of parasitic diseases)
  • Potassium-sparing diuretics (medicines for hypertension)
  • Lithium salts (medicines for psychiatric diseases)
  • Antithyroid drugs (medicines used in hyperthyroidism)

Taking NATIFAR with food, drinks, and alcohol

Do not take alcohol with this medicine, as it may reduce blood levels of folic acid.

Do not take green or black tea with this medicine because they can reduce blood levels of folic acid.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Pregnancy

Natifar is indicated before and during pregnancy, but the recommended dose should not be exceeded.

Since iodine crosses the placental barrier and the fetus is sensitive to pharmacologically active doses of iodine, iodine should not be administered at the milligram level.

Breastfeeding

Potassium iodide passes into breast milk. Natifar is not indicated for use during breastfeeding.

Driving and using machines

Natifar has no or negligible influence on the ability to drive and use machines.

3. How to take NATIFAR

Follow exactly the administration instructions of this medicine given by your doctor. If you are unsure, consult your doctor or pharmacist again.

The recommended dose is 1 tablet per day, preferably taken before a meal.

Administer orally with sufficient water.

The recommended treatment duration is one month before conception (or when planning a pregnancy) and, at medical discretion, during the first trimester of pregnancy.

Use in children and adolescents

Natifar is not indicated for children under 14 years of age.

If you take more NATIFAR than you should

Deliberate or accidental overdose is unlikely. Administration of high doses (in the range of milligrams) or for long periods of time may cause manifestations of iodism such as metallic taste, burning in the mouth and throat, painful sensitivity in teeth and gums, increased salivation, irritation of the nasal mucosa and eyes. It can also cause severe headache, productive cough, pulmonary edema (fluid accumulation in the lung), and swelling, and discomfort of the salivary glands. The pharynx, larynx, and tonsils may become inflamed.

In seborrheic areas, moderate eruptions (rashes) may appear, rarely severe eruptions.

Gastric irritation is common when very high doses are ingested and may cause diarrhea.

The signs and symptoms of iodism usually disappear spontaneously after a few days of stopping treatment.

The use of high doses of potassium iodide or for long periods of time can cause hyperplasia (increase) of the thyroid gland, thyroid adenoma (benign tumor), goiter, or severe hypothyroidism.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone 91 562 04 20, indicating the medicine and the amount ingested.

If you forget to take NATIFAR

Do not take a double dose to make up for forgotten doses.

Simply take the forgotten dose when you remember and take the next doses with the indicated interval between doses (24 hours).

If you stop taking NATIFAR

Your doctor will determine the duration of treatment with Natifar. Do not stop it or prolong it.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Uncommon side effects (may affect up to 1 in 100 people) are:

  • Hypersensitivity reactions, with skin rashes with itching, redness, and symptoms such as edema (swelling), including facial and glottis edema, and symptoms similar to serum sickness (fever, arthralgia (joint pain), lymph node enlargement, eosinophilia (increase in a type of white blood cell, eosinophils), urticaria (rash in the form of hives and itching), thrombocytopenic purpura (blood disorder characterized by low platelet count and red blood cells), fatal periarteritis (vascular disease in which small and medium-sized arteries become inflamed and damaged).
  • Goiter (enlargement of the thyroid gland).
  • Hyperthyroidism (very high levels of thyroid hormones) and hypothyroidism (very low levels of thyroid hormones).
  • Irregular heartbeat.

Side effects of unknown frequency are:

  • Severe allergic reaction (anaphylactic reaction).

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this package leaflet. You can also report side effects directly via the Spanish Medicines and Healthcare Products Agency's website: https://www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of NATIFAR

No special storage conditions are required.

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the packaging after EXP. The expiry date is the last day of the month shown.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help protect the environment.

6. Contents of the pack and further information

Composition of NATIFAR

  • The active substances are: potassium iodide, folic acid, and vitamin B12 (cyanocobalamin). Each tablet contains: potassium iodide, 262 micrograms (equivalent to 200 micrograms of iodine); folic acid, 400 micrograms; and vitamin B12 (cyanocobalamin), 2 micrograms.
  • The other ingredients (excipients) are: mannitol (E-421), microcrystalline cellulose, sodium glycolate starch, anhydrous colloidal silica, magnesium stearate, and maltodextrin.

Appearance of the product and contents of the pack

Tablets, round, yellow.

Each pack contains 28 tablets.

Marketing authorization holder and manufacturer

Marketing authorization holder:

DESMA Laboratorio Farmacéutico SL

Paseo de la Castellana 121, Escalera Izquierda 3ºB

28046 Madrid

Spain

Manufacturer:

FINE FOODS AND PHARMACEUTICALS N.T.M., S.P.A.

Via Grignano, 43

24041 Brembate (BG)

Italy

Date of last revision of this package leaflet: May 2024.

Detailed and up-to-date information on this medicine is available on the website of the Spanish Agency for Medicines and Healthcare Products (AEMPS) http://www.aemps.gob.es/

Online doctors for NATIFAR 200/400/2 micrograms TABLETS

Discuss questions about NATIFAR 200/400/2 micrograms TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (5)
Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

Camera Book a video appointment
€80
5.0 (1055)
Doctor

Andrei Popov

General medicine 7 years exp.

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

Camera Book a video appointment
€80
5.0 (41)
Doctor

Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
Camera Book a video appointment
€60
3
...

Frequently Asked Questions

Is a prescription required for NATIFAR 200/400/2 micrograms TABLETS?
NATIFAR 200/400/2 micrograms TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
How much does NATIFAR 200/400/2 micrograms TABLETS cost in pharmacies?
The average pharmacy price for NATIFAR 200/400/2 micrograms TABLETS is around 5.84 EUR. Prices may vary depending on the manufacturer and dosage form.
Who manufactures NATIFAR 200/400/2 micrograms TABLETS?
NATIFAR 200/400/2 micrograms TABLETS is manufactured by Desma Laboratorio Farmaceutico S.L.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of NATIFAR 200/400/2 micrograms TABLETS online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether NATIFAR 200/400/2 micrograms TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to NATIFAR 200/400/2 micrograms TABLETS?
Other medicines with the same active substance () include ASCORBIC ACID BAYER 1000 mg/5 ml INJECTABLE SOLUTION, ALDEXINA 25,000 IU HARD CAPSULES, ALDEXINA 50,000 IU HARD CAPSULES. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
bg-pattern-dark

Stay informed about Oladoctor

News about new services, product updates and useful information for patients.

Follow us on social media