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IMVANEX 5 x 10^7 IU Injectable

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Doctor
5.0(16)

Sergey Ilyasov

PsychiatryNeurology7 years of experience

Dr Sergey Ilyasov is an experienced neurologist and qualified psychiatrist who provides online consultations for adults and adolescents. Combining deep neurological expertise with a modern psychiatric approach, he ensures comprehensive diagnostics and effective treatment for a wide range of conditions affecting both physical and mental health.

Dr. Ilyasov helps patients in the following cases:

  • Chronic headaches (migraine, tension-type headache), back pain, neuropathic pain, dizziness, numbness in limbs, coordination disorders.
  • Anxiety disorders (panic attacks, generalized anxiety disorder), depression (including atypical and treatment-resistant forms), sleep disturbances (insomnia, hypersomnia, nightmares), stress, burnout.
  • Chronic pain syndromes and psychosomatic symptoms (e.g., irritable bowel syndrome related to stress, vegetative-vascular dystonia).
  • Behavioral disorders and concentration difficulties in adolescents (including ADHD, autism spectrum disorders), nervous tics.
  • Memory impairments, phobias, obsessive-compulsive disorder (OCD), emotional swings, and support for post-traumatic stress disorder (PTSD).

Thanks to his dual specialization in neurology and psychiatry, Dr Sergey Ilyasov offers integrated and evidence-based care for complex conditions requiring a multidisciplinary approach. His consultations focus on accurate diagnosis, development of an individualized treatment plan (including pharmacotherapy and psychotherapeutic methods), and long-term support adapted to each patient's unique needs.

Book an online consultation with Dr. Sergey Ilyasov to receive qualified assistance and improve your well-being today.

Book a video appointment
€106
This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use IMVANEX Injectable Suspension

Contents of the leaflet

  1. Introduction
  2. What is IMVANEX and what is it used for
  3. What you need to know before you are given IMVANEX
  4. How IMVANEX is given
  5. Possible side effects
  6. Storing IMVANEX
  7. Contents of the pack and other information

Introduction

Package Leaflet: Information for the User

IMVANEX injectable suspension

Vaccine against smallpox and monkeypox (modified Ankara vaccinia virus)

This medicine is subject to additional monitoring, which will allow for the quick identification of new safety information. You can help by reporting any side effects you may get. The last section of section 4 will tell you how to report side effects.

Read all of this leaflet carefully before you receive this vaccine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or nurse.
  • If you get any side effects, talk to your doctor or nurse. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack

  1. What is IMVANEX and what is it used for
  2. What you need to know before you are given IMVANEX
  3. How IMVANEX is given
  4. Possible side effects
  5. Storing IMVANEX
  6. Contents of the pack and other information

1. What is IMVANEX and what is it used for

IMVANEX is a vaccine used to prevent smallpox, monkeypox, and disease caused by cowpox virus in adults and adolescents from 12 years of age.

When the vaccine is given to a person, the immune system (the body's natural defense system) produces its own protection in the form of antibodies against the smallpox virus, monkeypox virus, and cowpox viruses.

IMVANEX does not contain the smallpox virus (Variola) or the monkeypox virus or the cowpox viruses. It cannot cause or spread infection and disease caused by the smallpox virus, monkeypox virus, or cowpox viruses.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you are given IMVANEX

You should not receive IMVANEX:

  • if you are allergic or have previously suffered a sudden and potentially life-threatening allergic reaction to the active substance or any of the other ingredients of this medicine (listed in section 6) or to chicken proteins, benzonase, gentamicin, or ciprofloxacin, which may be present in the vaccine in very small amounts.

Warnings and precautions

Talk to your doctor or nurse before receiving IMVANEX:

  • if you have atopic dermatitis (see section 4).
  • if you have an HIV infection or any other disease or treatment that weakens the immune system.
  • if you are nervous about receiving the vaccine or have ever fainted after an injection with a needle.

The efficacy of IMVANEX in protecting against smallpox, monkeypox, and disease caused by cowpox virus has not been studied in humans.

In case of illness with high fever, your doctor will postpone vaccination until you are better. The presence of a minor infection, such as a cold, should not require postponement of vaccination, but consult your doctor or nurse first.

It is possible that IMVANEX may not fully protect all people who receive the vaccine.

Previous vaccination with IMVANEX may alter the skin response ("take") to subsequent smallpox vaccines with replicating viruses and cause reduced or absent take of these vaccines.

Other medicines or vaccines and IMVANEX

Tell your doctor or nurse if you are taking or have recently taken any other medicine or if you have recently received any other vaccine.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor. The use of this vaccine is not recommended during pregnancy and breastfeeding. However, your doctor will assess whether the potential benefit of preventing smallpox, monkeypox, and disease caused by cowpox virus outweighs the potential risks to you and your baby.

Driving and using machines

No information is available on the effects of IMVANEX on the ability to drive or use machines. However, if you experience any of the side effects included in section 4, some of them may affect your ability to drive or use machines (e.g., dizziness).

IMVANEX contains sodium

This medicine contains less than 1 mmol of sodium (23 mg) per dose, which is essentially "sodium-free".

3. How IMVANEX is given

You can receive this vaccine whether or not you have been vaccinated against smallpox in the past.

Your doctor or nurse will inject the vaccine under your skin, preferably in the upper arm. It should not be injected into a blood vessel.

If you have never been vaccinated against smallpox, monkeypox, or cowpox viruses:

  • You will receive two injections.
  • The second injection will be given no less than 28 days after the first.
  • Make sure to complete the two-injection vaccination course.

If you have been previously vaccinated against smallpox, monkeypox, or cowpox viruses:

  • You will receive one injection.
  • If your immune system is weakened, you will receive two injections, and the second will be given no less than 28 days after the first.

If you miss an appointment for an IMVANEX injection

If you miss a scheduled injection, talk to your doctor or nurse and schedule another appointment.

If you have any other questions about the use of this vaccine, ask your doctor or nurse.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this vaccine can cause side effects, although not everybody gets them.

Serious side effects

Get in touch with a doctor or go immediately to the Emergency Department of the nearest hospital if you experience any of the following symptoms:

  • difficulty breathing
  • dizziness
  • swelling of the face and neck

These symptoms may be indicative of a severe allergic reaction.

Other side effects

If you already have atopic dermatitis, you may experience more intense local skin reactions (such as redness, swelling, and itching) and other general symptoms (such as headache, muscle pain, nausea, or fatigue), as well as an exacerbation or worsening of your skin problem.

The most frequently reported side effects occurred at the injection site. Most were mild to moderate and resolved without treatment within a period of seven days.

Tell your doctor if you experience any of the following side effects:

Very common(may affect more than 1 in 10 people):

  • headache
  • muscle pain
  • nausea
  • fatigue
  • pain, redness, swelling, induration, or itching at the injection site

Common(may affect up to 1 in 10 people):

  • chills
  • fever
  • joint pain, limb pain
  • loss of appetite
  • lump, discoloration, bruising, or warmth at the injection site

Uncommon(may affect up to 1 in 100 people):

  • nose and throat infection, upper respiratory tract infection
  • swelling of the lymph nodes
  • sleep disorders
  • dizziness, abnormal skin sensations
  • muscle stiffness
  • sore throat, nasal discharge, cough
  • diarrhea, vomiting
  • rash, itching, skin inflammation
  • bleeding, irritation
  • swelling under the arm, feeling unwell, flushing, chest pain
  • increased cardiac laboratory values (such as troponin I), increased liver enzymes, decreased white blood cell count, decreased platelet volume

Rare(may affect up to 1 in 1,000 people):

  • sinus infection
  • flu
  • redness and discomfort in the eye
  • hives (urticaria)
  • skin discoloration
  • sweating
  • skin bruising
  • night sweats
  • skin lump
  • back pain
  • neck pain
  • muscle cramps
  • muscle pain
  • muscle weakness
  • swelling of the ankles, feet, or toes
  • rapid heartbeat
  • ear and throat pain
  • abdominal pain
  • dry mouth
  • feeling of spinning (vertigo)
  • migraine
  • nervous disorder that causes weakness, numbness, or tingling
  • drowsiness
  • flaking, inflammation, abnormal sensation in the skin, reaction at the injection site, rash, numbness, dryness, reduced mobility, blisters at the injection site
  • weakness
  • pseudoinfluenza syndrome
  • swelling of the face, mouth, and throat
  • increased white blood cell count
  • bruising

Frequency not known(cannot be estimated from the available data):

  • temporary facial paralysis (Bell's palsy) on one side

Reporting of side effects

If you experience any side effects, talk to your doctor or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly through the national reporting system listed in Appendix V. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storing IMVANEX

Keep this medicine out of the sight and reach of children.

Do not use this vaccine after the expiry date which is stated on the label after EXP. The expiry date is the last day of the month shown.

Store in a freezer (at -20°C ± 5°C or -50°C ± 10°C or -80°C ± 10°C). The expiry date depends on the storage temperature. Do not re-freeze the vaccine once thawed. After thawing, the vaccine can be stored between 2°C and 8°C in the dark for a maximum of 2 months, within the approved validity period, before use.

Store in the original package to protect from light.

6. Contents of the pack and other information

What is in IMVANEX

One dose (0.5 ml) contains:

  • The active substance is the modified Ankara vaccinia virus - Bavarian Nordic1, at least 5 x 10^7 IU.*
  • infectious units

1 Produced in chicken embryo cells.

  • The other ingredients are: trometamol, sodium chloride, and water for injections.

This vaccine contains residual traces of chicken proteins, benzonase, gentamicin, and ciprofloxacin.

Appearance and packaging

After thawing, IMVANEX is a milky white to pale yellow injectable suspension.

IMVANEX is supplied as an injectable suspension in a vial (0.5 ml).

IMVANEX is available in packs of 1 vial or 20 vials.

Not all pack sizes may be marketed.

Marketing authorisation holder and manufacturer

Marketing authorisation holder

Bavarian Nordic A/S

Philip Heymans Allé 3

DK-2900 Hellerup

Denmark

Phone +45 3326 8383

Email [email protected]

Manufacturer

Bavarian Nordic A/S

Hejreskovvej 10A,

3490 Kvistgaard

Denmark

Date of last revision of this leaflet:

This medicine has been authorised under exceptional circumstances. This means that due to the rarity of this disease, it has not been possible to obtain complete information on this medicine.

The European Medicines Agency will review any new information that may become available every year and this leaflet will be updated as necessary.

More detailed information on this medicine is available on the European Medicines Agency web site: http://www.ema.europa.eu.

The leaflet is also available in all languages of the European Union/European Economic Area on the European Medicines Agency web site.

-------------------------------------------------------------------------------------------------------------------

This information is intended for healthcare professionals only:

Instructions for preparation and administration of the vaccine:

The vial should be allowed to reach a temperature between 8°C and 25°C before use. Shake gently before use. Visually inspect the suspension before administration. If particles or an abnormal appearance are observed, the vaccine should be discarded.

Each vial is for single use.

Draw up a dose of 0.5 ml into a syringe for injection.

After thawing, the vaccine can be stored between 2°C and 8°C in the dark for a maximum of 2 months, within the approved validity period, before use.

Do not re-freeze the vaccine once thawed.

In the absence of compatibility studies, this vaccine must not be mixed with other vaccines.

Online doctors for IMVANEX Injectable Suspension

Discuss questions about IMVANEX Injectable Suspension, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(16)

Sergey Ilyasov

PsychiatryNeurology7 years of experience

Dr Sergey Ilyasov is an experienced neurologist and qualified psychiatrist who provides online consultations for adults and adolescents. Combining deep neurological expertise with a modern psychiatric approach, he ensures comprehensive diagnostics and effective treatment for a wide range of conditions affecting both physical and mental health.

Dr. Ilyasov helps patients in the following cases:

  • Chronic headaches (migraine, tension-type headache), back pain, neuropathic pain, dizziness, numbness in limbs, coordination disorders.
  • Anxiety disorders (panic attacks, generalized anxiety disorder), depression (including atypical and treatment-resistant forms), sleep disturbances (insomnia, hypersomnia, nightmares), stress, burnout.
  • Chronic pain syndromes and psychosomatic symptoms (e.g., irritable bowel syndrome related to stress, vegetative-vascular dystonia).
  • Behavioral disorders and concentration difficulties in adolescents (including ADHD, autism spectrum disorders), nervous tics.
  • Memory impairments, phobias, obsessive-compulsive disorder (OCD), emotional swings, and support for post-traumatic stress disorder (PTSD).

Thanks to his dual specialization in neurology and psychiatry, Dr Sergey Ilyasov offers integrated and evidence-based care for complex conditions requiring a multidisciplinary approach. His consultations focus on accurate diagnosis, development of an individualized treatment plan (including pharmacotherapy and psychotherapeutic methods), and long-term support adapted to each patient's unique needs.

Book an online consultation with Dr. Sergey Ilyasov to receive qualified assistance and improve your well-being today.

Book a video appointment
€106
Doctor
5.0(11)

Anna Biriukova

Gastroenterology6 years of experience

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
Book a video appointment
€66
Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
Doctor
5.0(12)

Yevgen Yakovenko

General medicine12 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment
€72
Doctor
5.0(24)

Taisiia Proida

Psychiatry7 years of experience

Taisiia Proida is a general practitioner with a specialization in mental health and a cognitive behavioral therapist (CBT), a member of the European Psychiatric Association. She offers online consultations for adults aged 18 and over, combining evidence-based medicine with an individualised approach to mental health care. She specialises in consultations and ongoing support for a wide range of mental health concerns, including: 

  • Mood disorders: depression, bipolar disorder, postpartum depression.
  • Anxiety disorders: generalised anxiety, OCD, panic attacks, phobias.
  • Post-traumatic stress disorder (PTSD) and complex PTSD.
  • Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). Assessment is provided only after an initial psychiatric evaluation and during a follow-up appointment.
  • Personality disorders and emotional instability.
  • Cyclothymia and mood fluctuations.
  • Schizophrenia spectrum and related conditions.

Dr. Proida combines clinical expertise with an empathetic approach, offering structured support based on evidence-based practices. Her work integrates CBT techniques with medical management, with a focus on anxiety and depressive disorders. She works with clients from different countries and cultural backgrounds, adapting her communication style and recommendations to individual needs. With experience in international clinical trials (Pfizer, Merck), she values clarity, trust, and collaborative partnership in patient care.

Book a video appointment
€156
Doctor
5.0(3)

Lina Travkina

General medicine13 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.

  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.

  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.

  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.

  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.

  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.

  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.

  • Medical advice and follow-up consultations.

  • Test interpretation and diagnostic guidance.

  • Structured support for undiagnosed complaints.

  • Second opinion on diagnoses and treatment plans.

  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.

  • Post-operative recovery support and pain management.

  • Preconception counselling and postpartum support.

  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Book a video appointment
€75

Get IMVANEX Injectable Suspension Prescription Online

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Tell us your symptoms, history, and what medicine you're requesting.

2

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3

Doctor reviews your case

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4

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Electronic prescription sent to your email — valid across Spain.

Frequently Asked Questions

IMVANEX Injectable Suspension requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

IMVANEX Injectable Suspension is manufactured by Bavarian Nordic A/S. Pharmacy brands and packaging may differ depending on the distributor.

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether IMVANEX Injectable Suspension is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy IMVANEX Injectable Suspension in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

Other medicines with the same active substance () include ABRYSVO powder and solvent for injectable solution, AREXVY powder and suspension for injectable suspension, MRESVIA DISPERSION INJECTABLE IN PRE-FILLED SYRINGE. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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