HBVAXPRO 5 µg Injectable Suspension

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Doctor
5.0(36)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

Book a video appointment
€86
This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use HBVAXPRO 5 micrograms, PRE-FILLED SYRINGE INJECTABLE SUSPENSION

Contents of the leaflet

  1. Introduction
  2. What is HBVAXPRO 5 micrograms and what is it used for
  3. What you need to know before you or your child receive HBVAXPRO 5 micrograms
  4. How HBVAXPRO 5 micrograms is administered
  5. Possible side effects
  6. Storage of HBVAXPRO 5 micrograms
  7. Contents of the pack and further information

Introduction

Package Leaflet: Information for the User

HBVAXPRO5micrograms, suspension for injection in pre-filled syringe

Hepatitis B vaccine (recombinant DNA)

Read all of this leaflet carefully before you or your child are vaccinated because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor, pharmacist or nurse.
  • If you or your child experience any side effects, talk to your doctor, pharmacist or nurse, even if they are not listed in this leaflet. See section 4.

Contents of the package leaflet

  1. What is HBVAXPRO 5 micrograms and what is it used for
  2. What you need to know before you or your child receive HBVAXPRO 5 micrograms
  3. How HBVAXPRO 5 micrograms is administered
  4. Possible side effects
  5. Storage of HBVAXPRO 5 micrograms
  6. Contents of the pack and further information

1. What is HBVAXPRO 5 micrograms and what is it used for

This vaccine is indicated for active immunization against hepatitis B virus infection caused by all known subtypes, in individuals from birth to 15 years of age considered at risk of exposure to hepatitis B virus.

It can be expected that immunization with HBVAXPRO will also prevent hepatitis D, since hepatitis D does not occur in the absence of hepatitis B infection.

The vaccine does not prevent infections caused by other agents such as hepatitis A, hepatitis C, and hepatitis E, or by other pathogens known to infect the liver.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you or your child receive HBVAXPRO 5 micrograms

Do not use HBVAXPRO5micrograms

  • if you or your child are allergic to hepatitis B surface antigen or to any of the other components of HBVAXPRO (see section 6).
  • if you or your child have a severe illness with fever.

Warnings and precautions

May cause severe allergic reactions because it contains latex in the container.

Consult your doctor, pharmacist or nurse before you or your child receive HBVAXPRO 5 micrograms.

Other vaccines and HBVAXPRO5micrograms

HBVAXPRO can be administered at the same time as hepatitis B immunoglobulin, in different injection sites.

HBVAXPRO can be used to complete a primary immunization cycle or as a booster dose in individuals who have previously received another hepatitis B vaccine.

HBVAXPRO can be administered at the same time as some other vaccines, using different injection sites and syringes.

Tell your doctor, pharmacist or nurse if you or your child are taking or have recently taken any other medicines, including those obtained without a prescription.

Pregnancy and lactation

Caution should be exercised when prescribing the vaccine to pregnant or breastfeeding women.

Consult your doctor, pharmacist or nurse before using any medicine.

Driving and using machines

HBVAXPRO is expected to have no influence or negligible influence on the ability to drive and use machines.

HBVAXPRO5micrograms contains sodium:this medicine contains less than 23 mg of sodium (1 mmol) per dose; i.e., it is essentially "sodium-free".

3. How HBVAXPRO 5 micrograms is administered

Dose

The recommended dose per injection (0.5 ml) is 5 micrograms in individuals from birth to 15 years of age.

A vaccination cycle should include at least three injections.

Two vaccination schedules can be recommended:

  • two injections with a one-month interval followed by a third injection 6 months after the first administration (0, 1, 6 months).
  • if rapid immunity is required: three injections with a one-month interval and a fourth dose 1 year later (0, 1, 2, 12 months).

In case of recent exposure to hepatitis B virus, a first dose of HBVAXPRO can be administered along with the appropriate dose of immunoglobulin.

Some local vaccination schedules currently recommend a booster dose. Your doctor, pharmacist or nurse will inform you if you need a booster dose.

Method of administration

The doctor or nurse will administer the vaccine by injection into the muscle. The preferred injection site in newborns and infants is the upper part of the thigh. The preferred injection site in older children and adolescents is the muscle of the upper arm.

This vaccine should never be administered into a blood vessel.

Exceptionally, the vaccine can be administered subcutaneously in patients with thrombocytopenia (decreased blood platelets) or in individuals at risk of bleeding.

If you or your child miss a dose of HBVAXPRO5micrograms

If you or your child miss a scheduled injection, consult your doctor, pharmacist or nurse. Your doctor or nurse will decide when to administer the missed dose.

If you or your child have any further questions about the use of this product, ask your doctor, pharmacist or nurse.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this vaccine can cause side effects, although not everybody gets them.

As with other hepatitis B vaccines, in many cases, a causal relationship between side effects and the vaccine has not been established.

The most frequently observed side effects are injection site reactions: pain, redness, and induration.

Other side effects reported very rarely are:

  • Low platelet count, lymph node disease
  • Allergic reactions
  • Nervous system disorders such as tingling, facial paralysis, nerve inflammation including Guillain-Barré syndrome, optic nerve inflammation causing vision problems, brain inflammation, exacerbation of multiple sclerosis, multiple sclerosis, seizures, headache, dizziness, and fainting
  • Low blood pressure, blood vessel inflammation
  • Symptoms similar to asthma
  • Vomiting, nausea, diarrhea, abdominal pain
  • Skin reactions such as eczema, rash, itching, hives, and blistering of the skin, hair loss
  • Joint pain, arthritis, muscle pain, pain in a limb
  • Fatigue, fever, undefined disease, flu-like symptoms
  • Elevation of liver enzymes
  • Eye inflammation causing pain and redness

In children born very prematurely (at 28 weeks of gestation or earlier), longer-than-normal intervals between breaths may occur during the 2 or 3 days following vaccination.

Reporting of side effects

If you experience any side effects, talk to your doctor, pharmacist or nurse, even if they are not listed in this leaflet. You can also report side effects directly through the national reporting system listed in Appendix V. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of HBVAXPRO 5 micrograms

Keep this vaccine out of the sight and reach of children.

Do not use this vaccine after the expiry date stated on the label.

Store in a refrigerator (between 2°C and 8°C).

Do not freeze.

Store in the original packaging to protect from light.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and further information

Composition of HBVAXPRO5micrograms

  • The active substance is:

Hepatitis B surface antigen, recombinant (HBsAg)* ..... 5 micrograms Adsorbed on amorphous aluminum hydroxyphosphate sulfate (0.25 milligrams Al+)

  • produced in yeast Saccharomyces cerevisiae (strain 2150-2-3) by recombinant DNA technology.

The other ingredients are sodium chloride (NaCl), sodium borate, and water for injections.

Appearance and packaging ofHBVAXPRO5micrograms

HBVAXPRO 5 micrograms is a suspension for injection in a pre-filled syringe.

Pack sizes of 1, 10, 20, and 50 pre-filled syringes without a needle or with 2 separate needles.

Pack sizes of 1 and 10 pre-filled syringes with 1 separate needle.

Not all pack sizes may be marketed.

Marketing authorisation holder and manufacturer

Merck Sharp & Dohme B.V., Waarderweg 39, 2031 BN Haarlem, Netherlands

For further information about this vaccine, contact the local representative of the marketing authorisation holder.

België/Belgique/BelgienMSD BelgiumTél/Tel: +32(0)[email protected]

LietuvaUAB Merck Sharp & DohmeTel. +370 5 2780 [email protected]

Text in Bulgarian language with contact information of Merck Sharp and Dohme Bulgaria, including phone and email

Luxembourg/LuxemburgMSD BelgiumTél/Tel: +32 (0) [email protected]

Ceská republika

Merck Sharp & Dohme s.r.o.Tel.: +420 233 010 [email protected]

Magyarország

MSD Pharma Hungary Kft.Tel.: + [email protected]

DanmarkMSD Danmark ApSTlf.: +45 4482 [email protected]

MaltaMerck Sharp & Dohme Cyprus Limited.Tel: 8007 4433 (+356 99917558)[email protected]

DeutschlandMSD Sharp & Dohme GmbHTel.: +49 (0) 89 20 300 [email protected]

NederlandMerck Sharp & Dohme B.V.Tel: 0800 9999000 (+31 23 5153153)[email protected]

EestiMerck Sharp & Dohme OÜTel: +372 614 [email protected]

NorgeMSD (Norge) ASTlf: +47 32 20 73 [email protected]

Ελλ?δαMSD Α.Φ.Ε.Ε.Τηλ: +30 210 98 97 [email protected]

ÖsterreichMerck Sharp & Dohme Ges.m.b.H.Tel: +43 (0) 1 26 [email protected]

EspañaMerck Sharp & Dohme de España, S.A.Tel: +34 91 321 06 [email protected]

PolskaMSD Polska Sp. z o.o.Tel.: +48 22 549 51 [email protected]

FranceMSD FranceTél: +33 (0)1 80 46 40 40

PortugalMerck Sharp & Dohme, LdaTel: +351 21 [email protected]

HrvatskaMerck Sharp & Dohme d.o.o.Tel: +385 1 66 11 [email protected]

RomâniaMerck Sharp & Dohme Romania S.R.LTel: + 4021 529 29 [email protected]

IrelandMerck Sharp & Dohme Ireland (Human Health) LimitedTel: +353 (0)1 [email protected]

SlovenijaMerck Sharp & Dohme, inovativna zdravila d.o.o.Tel: +386 1 520 [email protected]

ÍslandVistor ehf.Sími: + 354 535 7000

Slovenská republikaMerck Sharp & Dohme, s. r. o.Tel: +421 2 [email protected]

ItaliaMSD Italia S.r.l.Tel: 800 23 99 89 (+39 06 361911)[email protected]

Suomi/FinlandMSD Finland OyPuh/Tel: +358 (0)9 804 [email protected]

Κ?προςMerck Sharp & Dohme Cyprus LimitedΤηλ: 800 00 673 (+357 22866700)[email protected]

SverigeMerck Sharp & Dohme (Sweden) ABTel: +46 77 [email protected]

LatvijaSIA Merck Sharp & Dohme LatvijaTel.: +371 [email protected]

Date of last revision of this leaflet:

Detailed information on this medicine is available on the European Medicines Agency website: https://www.ema.europa.eu.

This information is intended only for healthcare professionals:

Instructions

A visual inspection of the vaccine should be performed to detect any possible appearance of foreign particles and/or abnormal physical appearance of the contents before administration. The syringe should be shaken well until a slightly opaque white suspension is obtained.

The needle is fixed by twisting it in the direction of the clock hands until it is securely attached to the syringe.

Online doctors for HBVAXPRO 5 micrograms, PRE-FILLED SYRINGE INJECTABLE SUSPENSION

Discuss questions about HBVAXPRO 5 micrograms, PRE-FILLED SYRINGE INJECTABLE SUSPENSION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(36)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

Book a video appointment
€86
Doctor
5.0(12)

Yevgen Yakovenko

Family medicine12 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment
€72
Doctor
5.0(3)

Lina Travkina

Family medicine13 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
  • Structured support for undiagnosed complaints.
  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Book a video appointment
€75
Doctor
5.0(19)

Nuno Tavares Lopes

Family medicineGeneral medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Book a video appointment
€70

Get HBVAXPRO 5 micrograms, PRE-FILLED SYRINGE INJECTABLE SUSPENSION Prescription Online

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Frequently Asked Questions

Is a prescription required for HBVAXPRO 5 micrograms, PRE-FILLED SYRINGE INJECTABLE SUSPENSION?

HBVAXPRO 5 micrograms, PRE-FILLED SYRINGE INJECTABLE SUSPENSION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in HBVAXPRO 5 micrograms, PRE-FILLED SYRINGE INJECTABLE SUSPENSION?

The active ingredient in HBVAXPRO 5 micrograms, PRE-FILLED SYRINGE INJECTABLE SUSPENSION is hepatitis B, purified antigen. This information helps identify medicines with the same composition but different brand names.

Who manufactures HBVAXPRO 5 micrograms, PRE-FILLED SYRINGE INJECTABLE SUSPENSION?

HBVAXPRO 5 micrograms, PRE-FILLED SYRINGE INJECTABLE SUSPENSION is manufactured by Merck Sharp & Dohme B.V.. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of HBVAXPRO 5 micrograms, PRE-FILLED SYRINGE INJECTABLE SUSPENSION online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether HBVAXPRO 5 micrograms, PRE-FILLED SYRINGE INJECTABLE SUSPENSION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy HBVAXPRO 5 micrograms, PRE-FILLED SYRINGE INJECTABLE SUSPENSION in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy HBVAXPRO 5 micrograms, PRE-FILLED SYRINGE INJECTABLE SUSPENSION in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to HBVAXPRO 5 micrograms, PRE-FILLED SYRINGE INJECTABLE SUSPENSION?

Other medicines with the same active substance (hepatitis B, purified antigen) include ENGERIX-B 20 micrograms/1 ml, PRE-FILLED SYRINGE SUSPENSION FOR INJECTION, ENGERIX-B JUNIOR 10 micrograms/0.5 ml, PRE-FILLED SYRINGE SUSPENSION, FENDRIX, INJECTABLE SUSPENSION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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