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ETALPHA 2 micrograms INJECTABLE SOLUTION

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Doctor

Rita Isabel Calero Garcia

General medicine 2 years exp.

Dr. Rita Isabel Calero Garcia is a physician with extensive experience in emergency medical care, general medicine, and healthcare assistance in various clinical and out-of-hospital settings.

She currently works as a physician at the Canary Islands Emergency Service (Servicio de Urgencias Canario – SUC), where she is responsible for the assessment and care of patients in medical emergency situations, performing the initial diagnosis, patient stabilization, and coordination with hospital services when necessary.

She has also developed her professional activity within the Primary Care Management Service, providing consultations in general medicine. In this setting she is responsible for patient follow-up, management of acute and chronic conditions, as well as health promotion and disease prevention.

She has also worked as a physician in a mobile ICU unit, providing medical assistance in out-of-hospital emergencies, treating critical patients and participating in medicalized patient transport.

In addition, she has collaborated with the Red Cross, participating in healthcare support units, providing medical assistance at events and supporting emergency interventions.

Furthermore, she has provided medical services in the private sector with Salvaser, conducting clinical assessments of patients and providing healthcare services within private medical services.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use ETALPHA 2 micrograms INJECTABLE SOLUTION

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Etalpha 2 micrograms solution for injection

alfacalcidol

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

  • This medicine will be administered to you by a healthcare professional.
  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • If you experience any side effects, talk to your doctor or pharmacist, even if they are not listed in this leaflet. See section 4.

Contents of the package leaflet

  1. What is Etalpha and what is it used for
  2. What you need to know before you are given Etalpha
  3. How Etalpha is used
  4. Possible side effects
  5. Storage of Etalpha
  6. Contents of the pack and further information

1. What is Etalpha and what is it used for

Etalpha belongs to a group of medicines called vitamin D analogues that regulate calcium and phosphorus levels in your body.

The active substance of Etalpha is alfacalcidol. Alfacalcidol acts by being converted into calcitriol (the active form of vitamin D) in the liver.

This medicine is indicated in situations where there is an alteration of calcium and phosphorus metabolism due to reduced production of 1,25-dihydroxyvitamin D in patients undergoing long-term haemodialysis.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you are given Etalpha

Do not use Etalpha

  • if you are allergic to alfacalcidol or any of the other ingredients of this medicine (listed in section 6).
  • if you have high levels of calcium in your blood (hypercalcaemia).

As high levels of calcium in the blood (hypercalcaemia) may occur during treatment with Etalpha, you should be aware of the following signs and symptoms of hypercalcaemia:

  • loss of appetite (anorexia)
  • fatigue
  • nausea
  • vomiting
  • constipation or diarrhoea
  • increased urine production
  • sweating
  • headache
  • thirst
  • high blood pressure
  • drowsiness
  • dizziness

Warnings and precautions

Talk to your doctor or pharmacist before you start using Etalpha.

Be particularly careful with Etalpha if:

  • you have arteriosclerosis, cardiac valve sclerosis or kidney stones (nephrolithiasis). These conditions may worsen if you have high levels of calcium in your blood (hypercalcaemia).
  • you have lung tissue calcification.
  • you have renal bone disease or any kidney disorder. Phosphate binders may be used to maintain acceptable serum phosphorus levels.
  • you have inflammatory diseases such as sarcoidosis. These conditions have the potential to increase sensitivity to Etalpha.
  • you are being treated with heart medicines (cardiac glycosides). If your blood calcium levels become too high (hypercalcaemia), the use of these medicines may cause changes in your heart rhythm.

During treatment, your doctor will perform blood tests to monitor your calcium and phosphorus levels.

Using Etalpha with other medicines

Tell your doctor or pharmacist if you are using, have recently used or might use any other medicines.

It is particularly important that you tell your doctor if:

  • you are being treated with diuretics, calcium-containing preparations or other vitamin D-containing preparations, as these may increase the risk of high levels of calcium in your blood (hypercalcaemia).
  • you are being treated with medicines for epilepsy (barbiturates, phenytoin, carbamazepine or primidone). You may need a higher dose of Etalpha.
  • you are taking antacids that contain magnesium, as these may increase the risk of high levels of magnesium in your blood (hypermagnesaemia).
  • you are being treated with aluminium-containing preparations (such as aluminium hydroxide or sucralfate), as these may increase aluminium absorption.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.

Etalpha may be used during pregnancy and breastfeeding only if your doctor considers it essential.

Ask your doctor or pharmacist for advice before using any medicine.

Driving and using machines

Etalpha has no significant influence on the ability to drive and use machines.

However, dizziness may occur during treatment, which you should take into account if you drive or use machines.

Etalpha contains ethanol, propylene glycol and sodium

This medicine contains up to 160 mg of ethanol per dose (which corresponds to 4 micrograms of alfacalcidol), equivalent to 10% ethanol (alcohol). The amount in each dose of this medicine is equivalent to 4 ml of beer or 1.7 ml of wine.

The small amount of alcohol in this medicine does not produce any noticeable effect.

This medicine contains 415 mg of propylene glycol per millilitre, equivalent to 20.75 mg/kg/day (which corresponds to 0.1 micrograms/kg/day of alfacalcidol).

If the baby is less than 4 weeks old, talk to your doctor or pharmacist, especially if the baby has been given other medicines that contain propylene glycol or alcohol.

This medicine contains less than 23 mg (1 mmol) of sodium per millilitre, so it is essentially "sodium-free".

3. How Etalpha is used

Etalpha will be administered to you by a healthcare professional via intravenous injection.

Adults and children over 20 kg in weight:

The initial dose is 1 microgram (0.5 ml) per day.

Children under 20 kg in weight:

The initial dose is 0.05 micrograms (0.025 ml) per kilogram of body weight per day.

The maintenance dose is usually between 0.25 and 2 micrograms (0.125 to 1 ml) per day.

The ampoules should be shaken well before use.

Your doctor may adjust these doses according to your needs. To do this, your doctor will perform blood tests or may request other diagnostic tests.

When administered to patients undergoing dialysis, the initial dose for adults is 1 microgram (0.5 ml) per dialysis session. The maximum recommended dose is 6 micrograms (3 ml) per dialysis session and no more than 12 micrograms (6 ml) per week.

If you receive more Etalpha than you should

If you receive more Etalpha than you should, high levels of calcium in your blood may occur, which can be controlled by discontinuing treatment.

If your blood calcium levels are very high, you may need to be given a diuretic and intravenous fluids or you may be given corticosteroids.

In case of overdose or accidental ingestion, contact the Toxicology Information Service. Telephone 91 562 04 20, stating the medicine and the amount used.

If you miss a dose of Etalpha

Talk to your doctor as soon as possible to find out what to do in these cases.

If you stop treatment with Etalpha

Your doctor will tell you how long to use Etalpha. Do not stop treatment before then, as it may be harmful to your health.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Common side effects (may affect up to 1 in 10 people):

  • high levels of calcium in the blood
  • excessive phosphorus in the blood
  • abdominal pain and discomfort
  • skin rash
  • itching
  • excess calcium in the urine

Uncommon side effects (may affect up to 1 in 100 people):

  • confusion
  • headache
  • diarrhoea
  • vomiting
  • constipation
  • nausea
  • muscle pain
  • worsening of kidney function (including acute kidney failure)
  • kidney stones
  • calcium deposits in the kidneys
  • fatigue
  • tiredness
  • malaise
  • calcium deposits in non-osseous tissues

Rare side effects (may affect up to 1 in 1,000 people):

  • dizziness

Reporting of side effects:

If you experience any side effects, talk to your doctor or pharmacist, even if they are not listed in this leaflet. You can also report side effects directly to the Spanish Medicines Agency's website: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Etalpha

Keep this medicine out of the sight and reach of children.

Store in a refrigerator (between 2°C and 8°C).

Keep the ampoules in the outer packaging to protect them from light.

Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiry date is the last day of the month stated.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and further information

Composition of Etalpha

  • The active substance is alfacalcidol.

One millilitre of solution for injection contains 2 micrograms of alfacalcidol. Each ampoule contains 2 micrograms of alfacalcidol in 1 millilitre of solution for injection.

  • The other ingredients are ethanol, citric acid monohydrate, sodium citrate, propylene glycol and water for injections.

Appearance and packaging

Etalpha 2 micrograms is a colourless and transparent solution for injection, for intravenous administration, in amber glass ampoules. Each pack contains 10 ampoules.

Marketing authorisation holder

CHEPLAPHARM Arzneimittel GmbH

Ziegelhof 24

17489 Greifswald

Germany

Manufacturer

CENEXI SAS

Rue Marcel et Jacques Gaucher,

94120 Fontenay-sous-Bois (France)

For further information about this medicine, contact the local representative of the marketing authorisation holder:

Laboratorios Rubió, S.A.

Industria, 29 - Pol. Ind. Comte de Sert

08755 Castellbisbal (Barcelona)

Spain

Date of last revision of this leaflet: January 2022

Detailed and up-to-date information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/.

Online doctors for ETALPHA 2 micrograms INJECTABLE SOLUTION

Discuss questions about ETALPHA 2 micrograms INJECTABLE SOLUTION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Tarek Agami

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Dr. Tarek Agami is a general practitioner registered in both Portugal and Israel, with broad experience in family and preventive medicine. He offers online consultations for adults and children, providing personalised support for primary care needs, chronic disease management, and everyday health concerns.

Dr. Agami received clinical training and worked in leading medical institutions in Israel (Kaplan Medical Center, Barzilai Medical Center, Wolfson Medical Center) and Portugal (European Healthcare City, Viscura Internacional, Hospital Dr. José Maria Grande, Hospital Vila Franca de Xira). His approach combines international medical standards with individualised attention to each patient.

Main areas of consultation:

  • Diagnosis and treatment of acute and chronic conditions (high blood pressure, diabetes, respiratory infections, cardiovascular symptoms)
  • Evaluation of symptoms and guidance on further diagnostic testing
  • Preventive check-ups and regular health monitoring
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  • Treatment adjustments and lifestyle recommendations based on your personal history
Dr. Agami provides medical support for patients using GLP-1 medications (such as Ozempic or Mounjaro) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Portugal and Israel.

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  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
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  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
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Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

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Rita Isabel Calero Garcia

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Dr. Rita Isabel Calero Garcia is a physician with extensive experience in emergency medical care, general medicine, and healthcare assistance in various clinical and out-of-hospital settings.

She currently works as a physician at the Canary Islands Emergency Service (Servicio de Urgencias Canario – SUC), where she is responsible for the assessment and care of patients in medical emergency situations, performing the initial diagnosis, patient stabilization, and coordination with hospital services when necessary.

She has also developed her professional activity within the Primary Care Management Service, providing consultations in general medicine. In this setting she is responsible for patient follow-up, management of acute and chronic conditions, as well as health promotion and disease prevention.

She has also worked as a physician in a mobile ICU unit, providing medical assistance in out-of-hospital emergencies, treating critical patients and participating in medicalized patient transport.

In addition, she has collaborated with the Red Cross, participating in healthcare support units, providing medical assistance at events and supporting emergency interventions.

Furthermore, she has provided medical services in the private sector with Salvaser, conducting clinical assessments of patients and providing healthcare services within private medical services.

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His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

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  • acute respiratory symptoms (cough, sore throat, runny nose, fever)
  • viral illnesses such as colds and seasonal infections
  • gastrointestinal complaints (nausea, diarrhoea, abdominal pain, gastroenteritis)
  • sudden changes in how a child or adult feels
  • questions about existing treatment and whether adjustments are needed
  • renewal of prescriptions when clinically appropriate

Dr. Shalko works specifically with urgent and short-term problems, providing practical recommendations and helping patients determine the safest next step. She explains symptoms clearly, guides patients through decision-making and offers straightforward medical advice for everyday acute issues.She does not provide long-term management of chronic conditions, ongoing follow-up or comprehensive care plans for complex long-term illnesses. Her consultations are designed for acute symptoms, sudden concerns and situations where timely medical input is important.With clinical experience in both paediatrics and general medicine, Dr. Shalko confidently supports adults and children. Her communication style is clear, simple and reassuring, helping patients feel informed and supported throughout the consultation.

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Throughout her education and professional career, Dr. Trafimchuk has gained extensive experience in managing diseases of the skin, hair, and nails, as well as in the diagnosis, treatment, and prevention of sexually transmitted infections (STIs). Her clinical approach is based on evidence-based medicine, combined with personalized care tailored to each patient’s needs.

In her daily practice, she treats a wide range of dermatological conditions, including chronic inflammatory dermatoses such as acne, rosacea, atopic dermatitis, psoriasis, and eczema. She also has experience in treating pigmentation disorders, including melasma, post-inflammatory hyperpigmentation, and dyschromia.

She has developed a particular interest in trichology, treating various types of alopecia, chronic hair loss, and scalp disorders. In addition, she has experience in managing infectious dermatoses of fungal, viral, and bacterial origin, as well as in evaluating benign and suspicious skin lesions, with referral to specialized care when necessary.

With a strong interest in a comprehensive approach to skin health, she also treats scars, post-procedural skin changes, and conditions related to hormonal factors and aging, including those associated with pregnancy, menopause, and age-related skin changes.

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Chikeluo Okeke

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Dr Okeke focuses on general internal medicine and adult primary care, combining clinical accuracy with careful attention to lifestyle, personal context, and everyday health concerns. His consultations are particularly well suited for people who seek medical advice online, live abroad, or need clear guidance without unnecessary complexity.

He provides online consultations covering symptom assessment, prevention, and long-term management of chronic conditions, helping patients understand what is happening and decide on appropriate next steps.

Common reasons for consultation:

  • General internal medicine concerns and initial health assessment.
  • Acute symptoms such as fever, cough, infections, pain, or weakness.
  • Chronic conditions and treatment adjustment.
  • Blood pressure issues, fatigue, metabolic concerns.
  • Preventive consultations and routine check-ups.
  • Interpretation of laboratory results and medical reports.
  • Medical advice for patients receiving care online.

Dr Okeke is known for his clear communication, calm approach, and cultural awareness. He listens carefully, explains medical decisions in a structured way, and supports patients in making informed choices about their health.

Online consultations with Dr Chikeluo Okeke offer reliable internal medicine care without geographic limitations, focused on medical relevance, clarity, and patient comfort.

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Frequently Asked Questions

Is a prescription required for ETALPHA 2 micrograms INJECTABLE SOLUTION?

ETALPHA 2 micrograms INJECTABLE SOLUTION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in ETALPHA 2 micrograms INJECTABLE SOLUTION?

The active ingredient in ETALPHA 2 micrograms INJECTABLE SOLUTION is alfacalcidol. This information helps identify medicines with the same composition but different brand names.

Who manufactures ETALPHA 2 micrograms INJECTABLE SOLUTION?

ETALPHA 2 micrograms INJECTABLE SOLUTION is manufactured by Cheplapharm Arzneimittel Gmbh. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of ETALPHA 2 micrograms INJECTABLE SOLUTION online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether ETALPHA 2 micrograms INJECTABLE SOLUTION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy ETALPHA 2 micrograms INJECTABLE SOLUTION in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy ETALPHA 2 micrograms INJECTABLE SOLUTION in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to ETALPHA 2 micrograms INJECTABLE SOLUTION?

Other medicines with the same active substance (alfacalcidol) include ETALPHA 1 microgram INJECTABLE SOLUTION, ETALPHA 2 micrograms/ml ORAL DROPS IN SOLUTION, ALDEXINA 25,000 IU HARD CAPSULES. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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