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EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION

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About the medicine

How to use EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for thepatient

Eptifibatide Accord 0.75 mg/ml solution for infusionEFG

eptifibatide

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor, pharmacist, or nurse.
  • If you experience any side effects, talk to your doctor, pharmacist, or nurse, even if they are not listed in this leaflet. See section 4.

Contents of the pack

  1. What Eptifibatide Accord is and what it is used for
  2. What you need to know before you are given Eptifibatide Accord
  3. How to use Eptifibatide Accord
  4. Possible side effects
  5. Storage of Eptifibatide Accord
  6. Contents of the pack and other information

1. What Eptifibatide Accord is and what it is used for

Eptifibatide Accord is a platelet aggregation inhibitor. This means it helps prevent the formation of blood clots.

It is used in adults with severe coronary insufficiency characterized by spontaneous and recent chest pain with electrocardiographic changes or biological changes. It is usually administered together with aspirin and unfractionated heparin.

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2. What you need to know before you are given Eptifibatide Accord

You should not be given Eptifibatide Accord:

  • if you are allergic to eptifibatide or any of the other ingredients of this medicine (listed in section 6).
  • if you have recently had a gastrointestinal, intestinal, bladder, or other organ bleeding, for example, if you have observed abnormal blood in your stools or urine (except for menstrual bleeding) in the last 30 days.
  • if you have had a stroke within the last 30 days or any hemorrhagic stroke (also, make sure your doctor knows if you have ever had a stroke).
  • if you have had a brain tumor or a process that affects the blood vessels of the brain.
  • if you have undergone major surgery or have had a serious injury in the last 6 weeks.
  • if you have or have had bleeding problems.
  • if you have or have had blood coagulation problems or a low platelet count.
  • if you have or have had severe hypertension (high blood pressure).
  • if you have or have had severe liver or kidney problems.
  • if you have been treated with another medicine of the same type as Eptifibatide Accord.

If you have had any of the above situations, inform your doctor. If you have any questions, ask your doctor, pharmacist, or nurse.

Warnings and precautions:

  • Eptifibatide Accord is only recommended for use in adult patients hospitalized in coronary care units.
  • Eptifibatide Accord should not be used in children or adolescents under 18 years of age.
  • Before and during treatment with Eptifibatide Accord, blood samples will be analyzed as a safety measure to limit the possibility of unexpected bleeding.
  • During the use of Eptifibatide Accord, you will be carefully monitored for signs of unusual or unexpected bleeding.

Talk to your doctor or pharmacist or nurse before using Eptifibatide Accord.

Using Eptifibatide Accord with other medicines

To avoid the possibility of interactions with other medicines, inform your doctor, pharmacist, or nurse if you are using, have recently used, or may need to use any other medicine, including those obtained without a prescription.

Especially:

  • blood thinners (oral anticoagulants) or
  • medicines that prevent the formation of blood clots, such as warfarin, dipyridamole, ticlopidine, aspirin (except for those that may be received as part of the treatment with Eptifibatide Accord).

Pregnancy and breastfeeding

The use of Eptifibatide Accord is not normally recommended during pregnancy. Tell your doctor if you are pregnant, think you may be pregnant, or plan to become pregnant. Your doctor will assess whether the benefits of treatment with Eptifibatide Accord for you outweigh the potential risks for your baby.

If you are breastfeeding, breastfeeding should be interrupted during the treatment period.

3. How to use Eptifibatide Accord

Eptifibatide Accord is administered intravenously by direct injection followed by an infusion (drip solution). The administered dose is based on your weight. The recommended dose is 180 micrograms/kg administered in a bolus (rapid intravenous injection), followed by an infusion (drip solution) of 2.0 micrograms/kg/minute for a maximum of 72 hours. If you have kidney disease, the infusion dose may be reduced to 1.0 microgram/kg/minute.

If a percutaneous coronary intervention is performed during treatment with Eptifibatide Accord, the intravenous solution may be continued for a maximum of 96 hours.

You will also need to receive some doses of acetylsalicylic acid (aspirin) and heparin (if not contraindicated in your case).

If you have any further questions about the use of this product, ask your doctor, pharmacist, or nurse.

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4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Very common side effects

These may affect more than 1 in 10 people

  • minor or major bleeding (for example, blood in the urine, stools, vomiting blood, or bleeding from surgery)
  • anemia (decrease in the number of red blood cells or hematies in the blood).

Common side effects

These may affect up to 1 in 10 people

  • inflammation of a vein.

Uncommon side effects

These may affect up to 1 in 100 people

  • decrease in the number of platelets (blood cells necessary for coagulation)
  • decrease in blood flow to the brain.

Rare side effects

These may affect up to 1 in 10,000 people

  • severe bleeding (for example, bleeding in the abdomen, brain, or lungs)
  • fatal bleeding
  • severe decrease in the number of platelets (blood cells necessary for coagulation)
  • skin rash (such as hives or itching)
  • severe and sudden allergic reaction.

If you notice any signs of bleeding, tell your doctor, pharmacist, or nurse immediately. Very rarely, bleeding has been severe and even fatal. Safety measures to prevent this from happening include blood tests and careful monitoring by healthcare professionals who care for you.

If you show symptoms of a severe allergic reaction or skin rash, tell your doctor, pharmacist, or nurse immediately.

Other effects that may occur in patients who need this type of treatment include those related to the condition for which they are being treated, such as rapid or irregular heartbeats, low blood pressure, shock, or cardiac arrest.

Reporting of side effects

If you experience any side effects, talk to your doctor, pharmacist, or nurse, even if they are not listed in this leaflet.

You can also report side effects directly through the national reporting system included in Appendix V. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Eptifibatide Accord

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date (EXP) stated on the outer packaging and on the vial after (EXP). The expiry date is the last day of the month indicated.

Store in a refrigerator (between 2°C and 8°C).

Keep the vial in the outer packaging to protect it from light. However, during the administration of the Eptifibatide Accord solution, no protection from light is required.

Before use, the contents of the vial must be examined.

Do not use Eptifibatide Accord if particles or a color change are observed.

Once opened, the unused medicine should be discarded.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of the packaging and any unused medicines. This will help protect the environment.

6. Contents of the pack and other information

Composition of Eptifibatide Accord

  • The active substance is eptifibatide.
  • Eptifibatide Accord 0.75 ml: Each ml of solution for infusion contains 0.75 mg of eptifibatide. A 100 ml vial of solution for infusion contains 75 mg of eptifibatide.
  • The other ingredients are citric acid monohydrate, sodium hydroxide, and water for injectable preparations.

Appearance and packaging

Eptifibatide Accord 0.75 mg/ml solution for infusion: 100 ml vial, pack with one vial.

Eptifibatide Accord 0.75 mg/ml: The clear, colorless solution is contained in a 100 ml glass vial, closed with a butyl rubber stopper and aluminum flip-off cap.

Marketing authorization holder and manufacturer

Marketing authorization holder:

Accord Healthcare S.L.U.

World Trade Center, Moll de Barcelona, s/n,

Edifici Est 6ª planta,

08039 Barcelona, Spain

Manufacturer:

Accord Healthcare Limited

Sage House

319, Pinner Road, Harrow

Middlesex HA1 4HF

United Kingdom

Wessling Hungary Kft

Fòti ùt 56, Budapest 1047,

Hungary

Accord Healthcare Polska Sp.z o.o.,

ul. Lutomierska 50,95-200 Pabianice, Poland

Date of the last revision of this leaflet:

Detailed information on this medicine is available on the European Medicines Agency website: http://www.ema.europa.eu/

Online doctors for EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION

Discuss questions about EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Bulat Garipov

General medicine 15 years exp.

Dr. Bulat Garipov is a radiologist with more than 15 years of experience, specializing in magnetic resonance imaging (MRI). Throughout his professional career, he has worked in leading diagnostic imaging centers, both in on-site practice and teleradiology, which has allowed him to develop a broad and versatile approach to radiology.

Over the years, he has gained solid experience in interpreting MRI studies in various areas, including:

  •  Neuroimaging
  •  Musculoskeletal system (MSK)
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  •  Abdomen and pelvis
  •  Soft tissues

Additionally, Dr. Garipov is open to new collaboration opportunities in radiology and teleradiology projects. He offers his expertise in MRI, providing both first and second readings of studies, as well as advanced image interpretation, ensuring accurate and high-quality diagnostics.

You could consult Dr. Bulat Garipov in cases where accurate interpretation of MRI studies or a second expert opinion is required. His expertise is especially valuable in cases of suspected neurological conditions, back and joint pain, vascular disorders, as well as in the diagnosis of abdominal and pelvic diseases. The doctor also provides support in complex or unclear clinical situations, including the review of previously performed studies, which helps improve diagnostic accuracy and determine the optimal treatment strategy. A teleradiology format is available, allowing you to receive a professional opinion remotely.

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Doctor

Alexander Nazarchuk

Allergology 7 years exp.

Dr. Alexander Nazarchuk is a physician specialising in allergology and internal medicine. He provides online consultations for adults, following the principles of evidence-based medicine — no outdated treatments or unnecessary tests, with clear explanations and a personalised approach. He helps patients with a wide range of allergic and therapeutic conditions, from common day-to-day complaints to complex cases involving allergies, gastrointestinal issues, cardiovascular concerns, respiratory symptoms, and more.

You can consult Dr. Nazarchuk for:

  • Test interpretation and guidance on diagnostic plans.
  • Allergic rhinitis, hay fever, bronchial asthma (including severe cases).
  • Food and drug allergies, skin rashes, angioedema.
  • Atopic dermatitis, urticaria, contact allergies.
  • Allergen-specific immunotherapy (AIT) – initiation and ongoing management.
  • Abdominal pain, bloating, changes in bowel habits, nausea, heartburn.
  • High blood pressure and adjustment of baseline antihypertensive therapy.
  • Hyperlipidaemia and elevated cholesterol.
  • Cough, nasal congestion, fever, sore throat.
  • Anaemia, including iron deficiency and related conditions.
  • Other issues related to allergology and internal medicine.

During consultations, Dr. Nazarchuk takes a thorough, structured approach — analysing symptoms, identifying potential causes, and helping patients make informed decisions. Whether treatment, further investigation, or monitoring is needed, he explains each step clearly so you understand your health and how best to manage it.

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Doctor

Sviatoslav Chekhun

Oncology 13 years exp.

Dr. Sviatoslav Chekhun is a medical oncologist with international clinical and research experience, specializing in modern medical oncology and a personalized approach to cancer treatment.

Currently (since 2025), he works as a Medical Oncologist at Institut Català d’Oncologia (Girona, Spain). Previously, he completed his residency in Medical Oncology and was involved in clinical research at Hospital Universitari Germans Trias i Pujol.

Dr. Chekhun has a strong academic and scientific background. He served as a lecturer in Internal Medicine at O.O. Bohomolets National Medical University and conducted research in experimental oncology at the R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology.

Earlier in his career, he worked as a medical oncologist at the Kyiv City Clinical Oncological Center and contributed to regulatory evaluation of medicinal products at the State Expert Center of the Ministry of Health of Ukraine.

When to consult Dr. Chekhun:

  •  for diagnosis or clarification of a cancer diagnosis
  •  to obtain a second opinion on an existing treatment plan 
  •  when you need a personalized treatment strategy 
  •  for interpretation of test results, CT, MRI, PET-CT, and biopsies 
  •  when choosing between treatment options (chemotherapy, targeted therapy, immunotherapy) 
  •  in case of doubts about treatment strategy or disease progression 

Consultation format

Dr. Chekhun provides online consultations, where you can receive:

  •  expert second opinion 
  •  detailed case review 
  •  recommendations based on current international treatment guidelines 
  •  personalized treatment and follow-up plan 

Important:
Prescription and monitoring of medications must be carried out by your treating physician in an in-person (offline) setting. An online consultation does not replace a face-to-face visit but helps you make more informed decisions about your treatment.

Dr. Sviatoslav Chekhun combines clinical practice, research, and international experience, enabling him to provide patients with modern, evidence-based approaches in oncology.

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Frequently Asked Questions

Is a prescription required for EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION?
EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION?
The active ingredient in EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION is eptifibatide. This information helps identify medicines with the same composition but different brand names.
Who manufactures EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION?
EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION is manufactured by Accord Healthcare S.L.U.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION?
Other medicines with the same active substance (eptifibatide) include EPTIFIBATIDE ACCORD 2 mg/ml INJECTABLE SOLUTION, INTEGRILIN 0.75 mg/ml SOLUTION FOR INFUSION, INTEGRILIN 2 mg/ml INJECTABLE SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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