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EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION

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About the medicine

How to use EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for thepatient

Eptifibatide Accord 0.75 mg/ml solution for infusionEFG

eptifibatide

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor, pharmacist, or nurse.
  • If you experience any side effects, talk to your doctor, pharmacist, or nurse, even if they are not listed in this leaflet. See section 4.

Contents of the pack

  1. What Eptifibatide Accord is and what it is used for
  2. What you need to know before you are given Eptifibatide Accord
  3. How to use Eptifibatide Accord
  4. Possible side effects
  5. Storage of Eptifibatide Accord
  6. Contents of the pack and other information

1. What Eptifibatide Accord is and what it is used for

Eptifibatide Accord is a platelet aggregation inhibitor. This means it helps prevent the formation of blood clots.

It is used in adults with severe coronary insufficiency characterized by spontaneous and recent chest pain with electrocardiographic changes or biological changes. It is usually administered together with aspirin and unfractionated heparin.

Doctor consultation

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Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you are given Eptifibatide Accord

You should not be given Eptifibatide Accord:

  • if you are allergic to eptifibatide or any of the other ingredients of this medicine (listed in section 6).
  • if you have recently had a gastrointestinal, intestinal, bladder, or other organ bleeding, for example, if you have observed abnormal blood in your stools or urine (except for menstrual bleeding) in the last 30 days.
  • if you have had a stroke within the last 30 days or any hemorrhagic stroke (also, make sure your doctor knows if you have ever had a stroke).
  • if you have had a brain tumor or a process that affects the blood vessels of the brain.
  • if you have undergone major surgery or have had a serious injury in the last 6 weeks.
  • if you have or have had bleeding problems.
  • if you have or have had blood coagulation problems or a low platelet count.
  • if you have or have had severe hypertension (high blood pressure).
  • if you have or have had severe liver or kidney problems.
  • if you have been treated with another medicine of the same type as Eptifibatide Accord.

If you have had any of the above situations, inform your doctor. If you have any questions, ask your doctor, pharmacist, or nurse.

Warnings and precautions:

  • Eptifibatide Accord is only recommended for use in adult patients hospitalized in coronary care units.
  • Eptifibatide Accord should not be used in children or adolescents under 18 years of age.
  • Before and during treatment with Eptifibatide Accord, blood samples will be analyzed as a safety measure to limit the possibility of unexpected bleeding.
  • During the use of Eptifibatide Accord, you will be carefully monitored for signs of unusual or unexpected bleeding.

Talk to your doctor or pharmacist or nurse before using Eptifibatide Accord.

Using Eptifibatide Accord with other medicines

To avoid the possibility of interactions with other medicines, inform your doctor, pharmacist, or nurse if you are using, have recently used, or may need to use any other medicine, including those obtained without a prescription.

Especially:

  • blood thinners (oral anticoagulants) or
  • medicines that prevent the formation of blood clots, such as warfarin, dipyridamole, ticlopidine, aspirin (except for those that may be received as part of the treatment with Eptifibatide Accord).

Pregnancy and breastfeeding

The use of Eptifibatide Accord is not normally recommended during pregnancy. Tell your doctor if you are pregnant, think you may be pregnant, or plan to become pregnant. Your doctor will assess whether the benefits of treatment with Eptifibatide Accord for you outweigh the potential risks for your baby.

If you are breastfeeding, breastfeeding should be interrupted during the treatment period.

3. How to use Eptifibatide Accord

Eptifibatide Accord is administered intravenously by direct injection followed by an infusion (drip solution). The administered dose is based on your weight. The recommended dose is 180 micrograms/kg administered in a bolus (rapid intravenous injection), followed by an infusion (drip solution) of 2.0 micrograms/kg/minute for a maximum of 72 hours. If you have kidney disease, the infusion dose may be reduced to 1.0 microgram/kg/minute.

If a percutaneous coronary intervention is performed during treatment with Eptifibatide Accord, the intravenous solution may be continued for a maximum of 96 hours.

You will also need to receive some doses of acetylsalicylic acid (aspirin) and heparin (if not contraindicated in your case).

If you have any further questions about the use of this product, ask your doctor, pharmacist, or nurse.

Medicine questions

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4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Very common side effects

These may affect more than 1 in 10 people

  • minor or major bleeding (for example, blood in the urine, stools, vomiting blood, or bleeding from surgery)
  • anemia (decrease in the number of red blood cells or hematies in the blood).

Common side effects

These may affect up to 1 in 10 people

  • inflammation of a vein.

Uncommon side effects

These may affect up to 1 in 100 people

  • decrease in the number of platelets (blood cells necessary for coagulation)
  • decrease in blood flow to the brain.

Rare side effects

These may affect up to 1 in 10,000 people

  • severe bleeding (for example, bleeding in the abdomen, brain, or lungs)
  • fatal bleeding
  • severe decrease in the number of platelets (blood cells necessary for coagulation)
  • skin rash (such as hives or itching)
  • severe and sudden allergic reaction.

If you notice any signs of bleeding, tell your doctor, pharmacist, or nurse immediately. Very rarely, bleeding has been severe and even fatal. Safety measures to prevent this from happening include blood tests and careful monitoring by healthcare professionals who care for you.

If you show symptoms of a severe allergic reaction or skin rash, tell your doctor, pharmacist, or nurse immediately.

Other effects that may occur in patients who need this type of treatment include those related to the condition for which they are being treated, such as rapid or irregular heartbeats, low blood pressure, shock, or cardiac arrest.

Reporting of side effects

If you experience any side effects, talk to your doctor, pharmacist, or nurse, even if they are not listed in this leaflet.

You can also report side effects directly through the national reporting system included in Appendix V. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Eptifibatide Accord

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date (EXP) stated on the outer packaging and on the vial after (EXP). The expiry date is the last day of the month indicated.

Store in a refrigerator (between 2°C and 8°C).

Keep the vial in the outer packaging to protect it from light. However, during the administration of the Eptifibatide Accord solution, no protection from light is required.

Before use, the contents of the vial must be examined.

Do not use Eptifibatide Accord if particles or a color change are observed.

Once opened, the unused medicine should be discarded.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of the packaging and any unused medicines. This will help protect the environment.

6. Contents of the pack and other information

Composition of Eptifibatide Accord

  • The active substance is eptifibatide.
  • Eptifibatide Accord 0.75 ml: Each ml of solution for infusion contains 0.75 mg of eptifibatide. A 100 ml vial of solution for infusion contains 75 mg of eptifibatide.
  • The other ingredients are citric acid monohydrate, sodium hydroxide, and water for injectable preparations.

Appearance and packaging

Eptifibatide Accord 0.75 mg/ml solution for infusion: 100 ml vial, pack with one vial.

Eptifibatide Accord 0.75 mg/ml: The clear, colorless solution is contained in a 100 ml glass vial, closed with a butyl rubber stopper and aluminum flip-off cap.

Marketing authorization holder and manufacturer

Marketing authorization holder:

Accord Healthcare S.L.U.

World Trade Center, Moll de Barcelona, s/n,

Edifici Est 6ª planta,

08039 Barcelona, Spain

Manufacturer:

Accord Healthcare Limited

Sage House

319, Pinner Road, Harrow

Middlesex HA1 4HF

United Kingdom

Wessling Hungary Kft

Fòti ùt 56, Budapest 1047,

Hungary

Accord Healthcare Polska Sp.z o.o.,

ul. Lutomierska 50,95-200 Pabianice, Poland

Date of the last revision of this leaflet:

Detailed information on this medicine is available on the European Medicines Agency website: http://www.ema.europa.eu/

Online doctors for EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION

Discuss questions about EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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Chikeluo Okeke

General medicine 4 years exp.

Dr Chikeluo Okeke is an internal medicine doctor with extensive international clinical experience. Originally from Nigeria, he has worked across multiple European healthcare systems and currently practises in Sweden. This professional path has given him a strong understanding of different medical approaches and the ability to work effectively with patients from diverse cultural and linguistic backgrounds.

Dr Okeke focuses on general internal medicine and adult primary care, combining clinical accuracy with careful attention to lifestyle, personal context, and everyday health concerns. His consultations are particularly well suited for people who seek medical advice online, live abroad, or need clear guidance without unnecessary complexity.

He provides online consultations covering symptom assessment, prevention, and long-term management of chronic conditions, helping patients understand what is happening and decide on appropriate next steps.

Common reasons for consultation:

  • General internal medicine concerns and initial health assessment.
  • Acute symptoms such as fever, cough, infections, pain, or weakness.
  • Chronic conditions and treatment adjustment.
  • Blood pressure issues, fatigue, metabolic concerns.
  • Preventive consultations and routine check-ups.
  • Interpretation of laboratory results and medical reports.
  • Medical advice for patients receiving care online.

Dr Okeke is known for his clear communication, calm approach, and cultural awareness. He listens carefully, explains medical decisions in a structured way, and supports patients in making informed choices about their health.

Online consultations with Dr Chikeluo Okeke offer reliable internal medicine care without geographic limitations, focused on medical relevance, clarity, and patient comfort.

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Andrei Popov

General medicine 7 years exp.

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

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Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Doctor

Joao Silva

General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

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€55
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Doctor

Bulat Garipov

General medicine 15 years exp.

Dr. Bulat Garipov is a radiologist with more than 15 years of experience, specializing in magnetic resonance imaging (MRI). Throughout his professional career, he has worked in leading diagnostic imaging centers, both in on-site practice and teleradiology, which has allowed him to develop a broad and versatile approach to radiology.

Over the years, he has gained solid experience in interpreting MRI studies in various areas, including:

  •  Neuroimaging
  •  Musculoskeletal system (MSK)
  •  Angiography
  •  Abdomen and pelvis
  •  Soft tissues

Additionally, Dr. Garipov is open to new collaboration opportunities in radiology and teleradiology projects. He offers his expertise in MRI, providing both first and second readings of studies, as well as advanced image interpretation, ensuring accurate and high-quality diagnostics.

You could consult Dr. Bulat Garipov in cases where accurate interpretation of MRI studies or a second expert opinion is required. His expertise is especially valuable in cases of suspected neurological conditions, back and joint pain, vascular disorders, as well as in the diagnosis of abdominal and pelvic diseases. The doctor also provides support in complex or unclear clinical situations, including the review of previously performed studies, which helps improve diagnostic accuracy and determine the optimal treatment strategy. A teleradiology format is available, allowing you to receive a professional opinion remotely.

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€60

Frequently Asked Questions

Is a prescription required for EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION?
EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION?
The active ingredient in EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION is eptifibatide. This information helps identify medicines with the same composition but different brand names.
Who manufactures EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION?
EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION is manufactured by Accord Healthcare S.L.U.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to EPTIFIBATIDE ACCORD 0.75 mg/mL SOLUTION FOR INFUSION?
Other medicines with the same active substance (eptifibatide) include EPTIFIBATIDE ACCORD 2 mg/ml INJECTABLE SOLUTION, INTEGRILIN 0.75 mg/ml SOLUTION FOR INFUSION, INTEGRILIN 2 mg/ml INJECTABLE SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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