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DIPRIVAN 20 mg/ml EMULSION FOR INFUSION

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5.0 (195)
Doctor

Taisiia Proida

Family medicine 7 years exp.

Taisiia Proida is a general practitioner with a specialization in mental health and a cognitive behavioral therapist (CBT), a member of the European Psychiatric Association. She offers online consultations for adults aged 18 and over, combining evidence-based medicine with an individualised approach to mental health care. She specialises in consultations and ongoing support for a wide range of mental health concerns, including: 

  • Mood disorders: depression, bipolar disorder, postpartum depression.
  • Anxiety disorders: generalised anxiety, OCD, panic attacks, phobias.
  • Post-traumatic stress disorder (PTSD) and complex PTSD.
  • Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). Assessment is provided only after an initial psychiatric evaluation and during a follow-up appointment.
  • Personality disorders and emotional instability.
  • Cyclothymia and mood fluctuations.
  • Schizophrenia spectrum and related conditions.

Dr. Proida combines clinical expertise with an empathetic approach, offering structured support based on evidence-based practices. Her work integrates CBT techniques with medical management, with a focus on anxiety and depressive disorders. She works with clients from different countries and cultural backgrounds, adapting her communication style and recommendations to individual needs. With experience in international clinical trials (Pfizer, Merck), she values clarity, trust, and collaborative partnership in patient care.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use DIPRIVAN 20 mg/ml EMULSION FOR INFUSION

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Diprivan 20 mg/ml emulsion for infusion

Propofol

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

Keep this leaflet. You may need to read it again.

If you have any further questions, ask your doctor, pharmacist, or nurse.

If you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. See section 4.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor, pharmacist, or nurse.
  • If you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack:

  1. What is Diprivan and what is it used for
  2. What you need to know before you use Diprivan
  3. How to use Diprivan
  4. Possible side effects
  5. Storage of Diprivan
  6. Further information

1. What is Diprivan and what is it used for

Diprivan belongs to a group of medicines called “general anaesthetics”. General anaesthetics are used to produce unconsciousness (sleep) while surgery or other procedures are carried out. It can also be used to sedate you (make you feel drowsy but not completely asleep).

Diprivan 20 mg/ml is used for:

  • induction and maintenance of general anaesthesia in adults and children over 3 years of age.
  • sedation of patients over 16 years of age with assisted ventilation in intensive care.
  • sedation of adults and children over 3 years of age during diagnostic and surgical procedures, alone or in combination with local or regional anaesthesia.
Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you use Diprivan

Before you are given the anaesthetic, the anaesthetist, surgeon, or intensive care doctor will assess your medical condition and any treatment you are currently receiving.

Do not use Diprivan

  • If you are allergic (hypersensitive) to propofol or any of the other ingredients of this medicine (listed in section 6).
  • If you are allergic to soya or peanuts. This is because Diprivan contains soya oil.
  • In patients 16 years or younger for sedation in intensive care.

Warnings and precautions

Tell your doctor, pharmacist, or nurse before you start using Diprivan if:

  • you have ever had a fit or convulsion,
  • you have ever been told you have very high levels of fat in your blood or problems absorbing fats. In these cases, your doctor may need to check your blood fat levels,
  • you have any other health problems, such as heart, breathing, kidney, or liver problems, or if you have been feeling unwell for a long time,
  • you are taking any other medicines, including those you have bought without a prescription
  • your body has lost a lot of water (hypovolaemia),
  • you have had prolonged and/or intense diarrhoea,
  • you have ever been told you have a disease called “mitochondrial disease”,
  • you are elderly or debilitated,
  • you have had a head injury together with a high pressure in your head.

Before you have surgery or any other procedure that requires the administration of any type of anaesthesia, it is essential that you inform your doctor if you have a disease called “acute porphyria”.

In rare cases, if you are given propofol for a long time, you may develop a disease called propofol infusion syndrome (PRIS). This disease can damage the heart, muscles, or kidneys, cause other serious problems, and can even be fatal. However, your doctor will closely monitor you and take the necessary measures to prevent this from happening.

Children and adolescents

Diprivan is not recommended for use in newborns.

Diprivan 20 mg/ml is not recommended for use in children under 3 years of age.

Other medicines and Diprivan

Tell your doctor, pharmacist, or nurse if you are taking or have recently taken or might take any other medicines.

Tell your doctor before using Diprivan if you are taking any of the following medicines:

  • strong painkillers (opioid analgesics) for intense pain relief
  • medicines called “parasympatholytics” (e.g. medicines used to treat cramps, asthma, Parkinson's disease, and other medicines in this group)
  • benzodiazepines (medicines used to treat anxiety)
  • neostigmine (medicine used to treat a disease called myasthenia gravis)
  • ciclosporin (medicine used to prevent organ rejection in transplants)
  • rifampicin (medicine used to treat tuberculosis)
  • corticosteroids (medicines used to treat asthma, arthritis, immune system diseases, skin diseases, and other diseases)
  • medicines that strengthen the heart, such as digoxin (for the treatment of heart failure)
  • medicines used to treat epilepsy, such as phenytoin, phenobarbital, and others.
  • suxamethonium (muscle relaxant)
  • Midazolam (used to induce sedation [a very relaxed state of calm, drowsiness, or sleep] and to relieve anxiety and muscle tension).

Using Diprivan with food, drinks, and alcohol

You should avoid drinking alcohol for at least 8 hours before and after the administration of Diprivan.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor, pharmacist, or nurse for advice before you are given Diprivan.

Diprivan should not be given to pregnant women unless absolutely necessary.

If you are breastfeeding, you should not breastfeed while you are being given Diprivan and you should discard breast milk for 24 hours after the administration of Diprivan.

Driving and using machines

Diprivan may affect your ability to react. Your doctor or anaesthetist will tell you how long you should wait before driving or using machines and will advise you to be accompanied when returning home. The effects of propofol usually disappear within 12 hours after the end of administration.

Diprivan contains soya oil

Diprivan contains soya oil. Do not use this medicine if you are allergic to peanuts or soya.

Diprivan contains sodium

This medicine contains less than 1 mmol of sodium (23 mg) per dose; this is essentially “sodium-free”.

3. How to use Diprivan

  • Diprivan will be given to you by, or under the supervision of, your anaesthetist or intensive care doctor.
  • Diprivan is given by infusion (drip) into a vein, usually in the back of the hand or in the forearm. A needle or a thin plastic tube called a cannula may be used. For long surgical operations and in intensive care, an electric pump may be used to control the rate of administration.

The dose of Diprivan will vary depending on your age, weight, and physical condition. Your doctor will give you the correct dose to induce and maintain anaesthesia or to achieve the required level of sedation, carefully monitoring your responses and vital signs (pulse, blood pressure, breathing, etc.)

You may need to be given several medicines to make you sleep or feel drowsy, pain-free, breathing healthily, and with stable blood pressure. Your anaesthetist or intensive care doctor will decide which medicine to use and when it is necessary and will adjust the dose of Diprivan according to the medicines used.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

During induction and maintenance of anaesthesia or sedation with Diprivan, the following side effects may occur (while you are being given the injection or infusion or when you are drowsy or asleep). Your doctor will be monitoring you for the occurrence of side effects and, if they happen, will give you the appropriate treatment.

Very common: may affect more than 1 in 10 people

Pain at the injection site (while you are being given the injection, before you fall asleep).

Common: may affect up to 1 in 10 people

  • Headache during the recovery phase.
  • A slower heart rate.
  • Decrease in blood pressure (hypotension).
  • Changes in your breathing pattern during induction.
  • Nausea and vomiting during the recovery phase.

Uncommon: may affect up to 1 in 100 people

  • Thrombosis and phlebitis.
  • Coughing during maintenance of anaesthesia.

Rare: may affect up to 1 in 1,000 people

  • Tics and contractions of your body or spasms that may occur during induction, maintenance, and recovery of anaesthesia.
  • Coughing during induction of anaesthesia.

Very rare: may affect up to 1 in 10,000 people

  • Severe allergic reaction, including anaphylactic shock.
  • Unconsciousness after surgery.
  • Fluid accumulation in the lungs.
  • Pancreatitis (inflammation of the pancreas).
  • Discoloration of urine.
  • Sexual excitement.
  • Fever after surgery.
  • Tissue damage (necrosis) at the injection site.

Frequency not known (cannot be estimated from the available data):

  • Metabolic acidosis, increased potassium levels, increased blood fat levels.
  • Euphoria, abuse, and dependence on the medicine.
  • Involuntary movements.
  • Abnormal heart rhythm, loss of heart strength (heart failure), abnormal nerve signal to your heart detected on an electrocardiogram.
  • Increased liver size.
  • Muscle cell breakdown (rhabdomyolysis).
  • Breathing difficulties.
  • Prolonged and often painful erection (priapism).
  • Pain and inflammation at the injection site when Diprivan is administered outside the vein.
  • Kidney failure.
  • Hepatitis (liver inflammation), acute liver failure (symptoms can include yellowing of the skin and eyes, itching, dark urine, stomach pain, and liver tenderness [indicated by pain below the front edge of the right rib cage], sometimes with loss of appetite).

Reporting of side effects

If you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Spanish Medicines and Healthcare Products Agency (AEMPS) website: https://www.notificaram.es/. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Diprivan

Do not store above 25°C. Do not freeze.

Keep out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiry date refers to the last day of the month shown.

After dilution: use within 6 hours.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help protect the environment.

6. Further information

Composition of Diprivan 20 mg/ml

  • The active substance is propofol.
  • The other ingredients are refined soya oil, purified egg phosphatide, glycerol, sodium hydroxide, nitrogen, water for injection, and disodium edetate.

Appearance and packaging

This medicinal product is presented in boxes of one vial with 50 ml of emulsion.

Marketing authorisation holder and manufacturer

Marketing authorisation holder:

Aspen Pharma Trading Limited

3016 Lake Drive,

Citywest Business Campus,

Dublin 24, Ireland

Tel: +34 952 010 137

Manufacturer:

Corden Pharma S.P.A.

Caponago

Milan (Italy)

Local representative:

ASPEN PHARMACARE ESPAÑA, S.L.

Avenida Diagonal, 512,

Planta Interior 1, Oficina 4,

Barcelona, 08006, Spain

Date of last revision of this leaflet: 08/2024

Detailed and up-to-date information on this medicine is available on the website of the Spanish Medicines and Healthcare Products Agency (AEMPS) http://www.aemps.gob.es/

Online doctors for DIPRIVAN 20 mg/ml EMULSION FOR INFUSION

Discuss questions about DIPRIVAN 20 mg/ml EMULSION FOR INFUSION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Sviatoslav Chekhun

Oncology 13 years exp.

Dr. Sviatoslav Chekhun is a medical oncologist with international clinical and research experience, specializing in modern medical oncology and a personalized approach to cancer treatment.

Currently (since 2025), he works as a Medical Oncologist at Institut Català d’Oncologia (Girona, Spain). Previously, he completed his residency in Medical Oncology and was involved in clinical research at Hospital Universitari Germans Trias i Pujol.

Dr. Chekhun has a strong academic and scientific background. He served as a lecturer in Internal Medicine at O.O. Bohomolets National Medical University and conducted research in experimental oncology at the R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology.

Earlier in his career, he worked as a medical oncologist at the Kyiv City Clinical Oncological Center and contributed to regulatory evaluation of medicinal products at the State Expert Center of the Ministry of Health of Ukraine.

When to consult Dr. Chekhun:

  •  for diagnosis or clarification of a cancer diagnosis
  •  to obtain a second opinion on an existing treatment plan 
  •  when you need a personalized treatment strategy 
  •  for interpretation of test results, CT, MRI, PET-CT, and biopsies 
  •  when choosing between treatment options (chemotherapy, targeted therapy, immunotherapy) 
  •  in case of doubts about treatment strategy or disease progression 

Consultation format

Dr. Chekhun provides online consultations, where you can receive:

  •  expert second opinion 
  •  detailed case review 
  •  recommendations based on current international treatment guidelines 
  •  personalized treatment and follow-up plan 

Important:
Prescription and monitoring of medications must be carried out by your treating physician in an in-person (offline) setting. An online consultation does not replace a face-to-face visit but helps you make more informed decisions about your treatment.

Dr. Sviatoslav Chekhun combines clinical practice, research, and international experience, enabling him to provide patients with modern, evidence-based approaches in oncology.

5.0 (194)
Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

5.0 (43)
Doctor

Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

0.0 (13)
Doctor

Daria Portnova

Psychiatry 31 years exp.

Dr Daria Portnova is a psychiatrist and psychotherapist with over 30 years of clinical experience. She works with adults and adolescents aged 14 and over, providing online psychiatric and psychotherapeutic consultations. In her practice, Dr Portnova supports patients facing the onset of mental health conditions, chronic psychiatric disorders, psychotic symptoms, trauma-related states, and complex emotional crises. Her work is structured and safety-focused, with an emphasis on stabilisation, accurate diagnosis, and long-term improvement in quality of life. Patients consult Dr Daria Portnova for the following concerns: 

  • existential crises and complex life situations;
  • loss, grief, and emotional exhaustion;
  • relationship difficulties, separation, and divorce;
  • psychological and psychiatric trauma, including complex PTSD (cPTSD);
  • anxiety disorders: generalised anxiety disorder and panic disorder;
  • social anxiety and social phobia;
  • obsessive-compulsive disorder (OCD);
  • sleep disorders;
  • depressive disorders;
  • bipolar affective disorder;
  • schizoaffective disorder;
  • schizophrenia;
  • personality disorders.

Dr Portnova combines psychiatric assessment with a psychotherapeutic approach. She works with evidence-based methods, including cognitive behavioural therapy (CBT) and third-wave approaches such as ACT, FACT, and CFT. Consultations are focused on clear clinical understanding, practical recommendations, and ongoing support over time.

5.0 (195)
Doctor

Taisiia Proida

Family medicine 7 years exp.

Taisiia Proida is a general practitioner with a specialization in mental health and a cognitive behavioral therapist (CBT), a member of the European Psychiatric Association. She offers online consultations for adults aged 18 and over, combining evidence-based medicine with an individualised approach to mental health care. She specialises in consultations and ongoing support for a wide range of mental health concerns, including: 

  • Mood disorders: depression, bipolar disorder, postpartum depression.
  • Anxiety disorders: generalised anxiety, OCD, panic attacks, phobias.
  • Post-traumatic stress disorder (PTSD) and complex PTSD.
  • Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). Assessment is provided only after an initial psychiatric evaluation and during a follow-up appointment.
  • Personality disorders and emotional instability.
  • Cyclothymia and mood fluctuations.
  • Schizophrenia spectrum and related conditions.

Dr. Proida combines clinical expertise with an empathetic approach, offering structured support based on evidence-based practices. Her work integrates CBT techniques with medical management, with a focus on anxiety and depressive disorders. She works with clients from different countries and cultural backgrounds, adapting her communication style and recommendations to individual needs. With experience in international clinical trials (Pfizer, Merck), she values clarity, trust, and collaborative partnership in patient care.

5.0 (109)
Doctor

Sergey Ilyasov

Psychiatry 7 years exp.

Dr Sergey Ilyasov is an experienced neurologist and qualified psychiatrist who provides online consultations for adults and adolescents. Combining deep neurological expertise with a modern psychiatric approach, he ensures comprehensive diagnostics and effective treatment for a wide range of conditions affecting both physical and mental health.

Dr. Ilyasov helps patients in the following cases:

  • Chronic headaches (migraine, tension-type headache), back pain, neuropathic pain, dizziness, numbness in limbs, coordination disorders.
  • Anxiety disorders (panic attacks, generalized anxiety disorder), depression (including atypical and treatment-resistant forms), sleep disturbances (insomnia, hypersomnia, nightmares), stress, burnout.
  • Chronic pain syndromes and psychosomatic symptoms (e.g., irritable bowel syndrome related to stress, vegetative-vascular dystonia).
  • Behavioral disorders and concentration difficulties in adolescents (including ADHD, autism spectrum disorders), nervous tics.
  • Memory impairments, phobias, obsessive-compulsive disorder (OCD), emotional swings, and support for post-traumatic stress disorder (PTSD).

Thanks to his dual specialization in neurology and psychiatry, Dr Sergey Ilyasov offers integrated and evidence-based care for complex conditions requiring a multidisciplinary approach. His consultations focus on accurate diagnosis, development of an individualized treatment plan (including pharmacotherapy and psychotherapeutic methods), and long-term support adapted to each patient's unique needs.

Book an online consultation with Dr. Sergey Ilyasov to receive qualified assistance and improve your well-being today.

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Frequently Asked Questions

Is a prescription required for DIPRIVAN 20 mg/ml EMULSION FOR INFUSION?

DIPRIVAN 20 mg/ml EMULSION FOR INFUSION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in DIPRIVAN 20 mg/ml EMULSION FOR INFUSION?

The active ingredient in DIPRIVAN 20 mg/ml EMULSION FOR INFUSION is propofol. This information helps identify medicines with the same composition but different brand names.

Who manufactures DIPRIVAN 20 mg/ml EMULSION FOR INFUSION?

DIPRIVAN 20 mg/ml EMULSION FOR INFUSION is manufactured by Aspen Pharma Trading Limited. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of DIPRIVAN 20 mg/ml EMULSION FOR INFUSION online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether DIPRIVAN 20 mg/ml EMULSION FOR INFUSION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy DIPRIVAN 20 mg/ml EMULSION FOR INFUSION in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy DIPRIVAN 20 mg/ml EMULSION FOR INFUSION in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to DIPRIVAN 20 mg/ml EMULSION FOR INFUSION?

Other medicines with the same active substance (propofol) include DIPRIVAN 10 mg/ml Injectable Emulsion for Infusion, PROPOFOL BAXTER 10mg/ml Injectable Emulsion for Infusion, PROPOFOL BAXTER 20mg/ml Injectable Emulsion for Infusion. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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