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SODIUM CHLORIDE FRESENIUS KABI 5.84% INJECTABLE SOLUTION

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About the medicine

How to use SODIUM CHLORIDE FRESENIUS KABI 5.84% INJECTABLE SOLUTION

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

PACKAGE LEAFLET: INFORMATION FOR THE USERSodium Chloride Fresenius Kabi 5.84% solution for injection

Read all of this leaflet carefully before you start using this medicine.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you experience any of the side effects, or if you notice any side effects not mentioned in this leaflet, please tell your doctor or pharmacist.

In this leaflet:

  1. What Sodium Chloride Fresenius Kabi is and what it is used for
  2. Before you use Sodium Chloride Fresenius Kabi
  3. How to use Sodium Chloride Fresenius Kabi
  4. Possible side effects
  5. Storage of Sodium Chloride Fresenius Kabi
  6. Further information

1. What Sodium Chloride Fresenius Kabi is and what it is used for

Sodium Chloride Fresenius Kabi is a solution for injection, which belongs to the group of medicines called electrolyte solutions.

Sodium Chloride Fresenius Kabi is indicated for the treatment of severe hyponatremia (low sodium levels in the blood) of various causes.

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2. Before you use Sodium Chloride Fresenius Kabi

Do not use Sodium Chloride Fresenius Kabi:

  • if you are allergic (hypersensitive) to the active substance or any of the other ingredients of Sodium Chloride Fresenius Kabi.
  • if you have edema (excessive fluid accumulation)
  • if you have eclampsia (seizures not attributed to any other cause during pregnancy)
  • if you have hypernatremia (high sodium levels in the blood)

Be cautious when using Sodium Chloride Fresenius Kabi:

Sodium chloride should be used with extreme caution in patients with heart failure, severe renal insufficiency (significant reduction in kidney function), liver cirrhosis (chronic progressive liver disease), and in those receiving corticosteroids or corticotropin (medicines used as anti-inflammatory agents). It should also be used with caution in elderly patients and those recovering from surgery.

Excess chloride in the body can cause a loss of bicarbonate, resulting in a decrease in pH. Excessive intravenous administration of sodium chloride can also lead to low potassium levels in the blood.

The coexistence of insufficient blood oxygenation and low sodium levels in the blood can cause brain damage, even in the absence of any correction of the low sodium levels in the blood.

It should be administered with caution in patients with high blood pressure.

If administered continuously in the same injection site, it can cause pain, infection, and phlebitis (inflammation of the vein wall).

Consult your doctor, even if any of the above circumstances have occurred to you in the past.

Use of other medicines:

Before mixing with other medicines, check the compatibility tables, consider the pH, and monitor the ions.

The concomitant administration of sodium chloride and corticosteroids or corticotropin (medicines used as anti-inflammatory agents) can lead to excessive fluid accumulation due to the sodium content.

The interaction between sodium and lithium (a medicine used to treat certain psychiatric disorders) is clinically significant. Excess sodium can prevent the establishment of adequate lithium levels, and conversely, a deficiency of sodium chloride can lead to an increase in lithium levels to toxic values.

Note that these instructions may also apply to medicines that have been used before or may be used after.

Tell your doctor or pharmacist if you are using or have recently used any other medicines, including those obtained without a prescription.

Pregnancy and breastfeeding:

Consult your doctor or pharmacist before using any medicine.

The safety of its use during pregnancy and breastfeeding has not been established. Therefore, it should only be used when clearly necessary and when the benefits justify the potential risks to the fetus or infant.

Driving and using machines:

This is not applicable due to the characteristics of its use.

3. How to use Sodium Chloride Fresenius Kabi:

Follow exactly the administration instructions of Sodium Chloride Fresenius Kabi as indicated by your doctor. Consult your doctor or pharmacist if you have any doubts.

The doses will be adapted to the patient's needs according to medical criteria based on age, weight, clinical status, fluid balance, ions, and acid-base balance.

Sodium Chloride Fresenius Kabi is administered intravenously, intramuscularly, or subcutaneously.

It is not necessary to sterilize the ampoule before opening. No cutting element is required to open the ampoule. Once the ampoule is opened, the nozzle fits perfectly onto the cone of the syringe (Luer cone), so it is not necessary to use a needle.

To open, separate one ampoule from the rest, twist one ampoule around itself against the rest of the ampoules on the strip without touching the head and neck of the ampoules (1). Shake the ampoule with a single movement as shown in the drawing to eliminate any liquid that may be in the stopper (2). To open the ampoule, twist the body and head of the ampoule in opposite directions until it breaks at the neck (3). Connect the Luer or Luer-lock syringe as shown in the drawing (4).

Sequence of four steps showing hand holding auto-injector pen pressing against abdominal skin

The solution does not contain any preservative or bactericide, so opened and unused ampoules must be discarded immediately.

If you use more Sodium Chloride Fresenius Kabi than you should:

Accidental overdose can lead to the symptoms described for excess sodium in the blood, and the measures to be taken will be those corresponding to the reduction of high sodium levels in the blood.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone 91 562 04 20, indicating the medicine and the amount used. It is recommended to take the packaging and leaflet to the healthcare professional.

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4. Possible side effects

Like all medicines, Sodium Chloride Fresenius Kabi can cause side effects.

Since sodium chloride is part of the normal composition of the internal medium, adverse reactions would be related to its concentration, which is higher than that of blood serum.

The adverse effects described have been due to excessive or too rapid administration. There are two forms of toxicity: the first is high sodium levels in the blood, and the second is an excess of sodium and water that can lead to excessive fluid accumulation, affecting the brain, lungs, or peripheral circulation. The symptoms of excess sodium are nausea, vomiting, diarrhea, abdominal cramps, thirst, reduced tear and saliva production, excessive sweating, fever, tachycardia, increased blood pressure, kidney failure, excessive fluid accumulation in different areas of the body and in the lungs, respiratory arrest, headache, dizziness, restlessness, weakness, muscle tremors and stiffness, seizures, coma, and death. However, most of the hypernatremias described have been as a result of the use of oral sodium chloride solutions and not due to the intravenous use of solutions with a sodium concentration higher than that of blood serum.

The administration of significant amounts of chloride can lead to a decrease in the body's pH as a consequence of the decrease in bicarbonate concentration.

If you experience any of the side effects, or if you notice any side effects not mentioned in this leaflet, please tell your doctor or pharmacist.

5. Storage of Sodium Chloride Fresenius Kabi

Keep out of the reach and sight of children.

No special storage conditions are required.

Do not use Sodium Chloride Fresenius Kabi after the expiration date stated on the packaging after EXP. The expiration date is the last day of the month indicated.

Do not use this medicine if you notice that the solution is not transparent, colorless, and free of particles.

Once the packaging is opened, the product must be used immediately.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of the packaging and any unused medicine. This will help protect the environment.

6. Further information

Composition of Sodium Chloride Fresenius Kabi

  • The active substance is: sodium chloride. Each ml of solution contains 58.4 mg of sodium chloride (ionic content: Na+ = Cl- = 1 mEq/ml).

Other ingredients are: water for injection and hydrochloric acid or sodium hydroxide.

Appearance and packaging of the product

Sodium Chloride Fresenius Kabi is a transparent and colorless solution, free or practically free of particles.

Sodium Chloride Fresenius Kabi is available in the following formats:

Box of 20 ampoules of 10 ml

Box of 50 ampoules of 10 ml

Box of 20 ampoules of 20 ml

Not all pack sizes may be marketed.

Marketing authorization holder and manufacturer

Fresenius Kabi España S.A.U. Marina 16-18

08005 – Barcelona

This leaflet was approved in October 2019

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gov.es/

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This information is intended only for healthcare professionals:

Solution for infusion for intravenous administration.

The ampoule of Sodium Chloride Fresenius Kabi should be diluted in a minimum volume of 50 ml of an infusion solution.

Use only if the solution is transparent and free of visible particles. If not all of the contents are used, discard the remainder.

In severe acute hyponatremia, rates of 1 mmol/l/hour are recommended to prevent neurological damage.

If the hyponatremia is chronic, furosemide or an osmotic diuretic should be associated with hypertonic saline solution.

Correction of hyponatremia should not be excessively rapid to avoid demyelinating lesions. Some authors recommend not exceeding a correction of 10 mEq/l in the first 24 hours and 21 mEq/l in the first 48 hours. In general, serum sodium levels should be monitored to stop replacement when normal values are reached.

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Discuss questions about SODIUM CHLORIDE FRESENIUS KABI 5.84% INJECTABLE SOLUTION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
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  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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Andrei Popov

General medicine 7 years exp.

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

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Joao Silva

General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

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Frequently Asked Questions

Is a prescription required for SODIUM CHLORIDE FRESENIUS KABI 5.84% INJECTABLE SOLUTION?
SODIUM CHLORIDE FRESENIUS KABI 5.84% INJECTABLE SOLUTION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in SODIUM CHLORIDE FRESENIUS KABI 5.84% INJECTABLE SOLUTION?
The active ingredient in SODIUM CHLORIDE FRESENIUS KABI 5.84% INJECTABLE SOLUTION is sodium chloride. This information helps identify medicines with the same composition but different brand names.
Who manufactures SODIUM CHLORIDE FRESENIUS KABI 5.84% INJECTABLE SOLUTION?
SODIUM CHLORIDE FRESENIUS KABI 5.84% INJECTABLE SOLUTION is manufactured by Fresenius Kabi España, S.A.U.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of SODIUM CHLORIDE FRESENIUS KABI 5.84% INJECTABLE SOLUTION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether SODIUM CHLORIDE FRESENIUS KABI 5.84% INJECTABLE SOLUTION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to SODIUM CHLORIDE FRESENIUS KABI 5.84% INJECTABLE SOLUTION?
Other medicines with the same active substance (sodium chloride) include POTASSIUM ACETATE B.BRAUN 1 mEq/ml CONCENTRATE FOR INFUSION SOLUTION, SODIUM BICARBONATE 1/6 M MEIN SOLUTION FOR INFUSION, SODIUM BICARBONATE 1M GRIFOLS INJECTABLE SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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