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CADELIUS D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS

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About the medicine

How to use CADELIUS D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Cadelius D 600 mg/1,000 UI Oral Dispersible Tablets

Calcium carbonate/colecalciferol

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor, pharmacist, or nurse.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack

  1. What Cadelius D is and what it is used for
  2. What you need to know before you take Cadelius D
  3. How to take Cadelius D
  4. Possible side effects
  5. Storing Cadelius D
  6. Contents of the pack and other information

1. What Cadelius D is and what it is used for

Cadelius D is used to prevent and treat calcium or vitamin D3 deficiency in elderly people and as additional treatment in osteoporosis in patients at risk of vitamin D or calcium deficiency when a dietary supplement of 600 mg/day of calcium and 1,000 IU/day of vitamin D3 is appropriate.

Cadelius D contains calcium and vitamin D3, both important components in bone formation. Vitamin D3 regulates the absorption and metabolism of calcium as well as the incorporation of calcium into bone tissue.

Ask your doctor or pharmacist if you have any questions and always follow their instructions.

You should consult a doctor if it worsens or does not improve after a few days.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you take Cadelius D

Do not take Cadelius D

  • If you are allergic to calcium, vitamin D, or any of the other ingredients of this medicine (listed in section 6).
  • If you have hypercalcemia (high levels of calcium in the blood) or hypercalciuria (high levels of calcium in the urine).
  • If you have hypervitaminosis D (high levels of vitamin D in the blood).
  • If you have kidney stones.
  • If you have kidney failure.
  • If you are allergic to soy or peanuts.

Warnings and precautions

Consult your doctor or pharmacist before taking Cadelius D

  • if you have sarcoidosis (a special type of connective tissue disease that affects the lungs, skin, and joints).
  • if you are taking other medicines that contain vitamin D or calcium.
  • if your kidneys do not work well or you have a tendency to form kidney stones.
  • if you are immobilized due to osteoporosis.

Other medicines and Cadelius D

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.

The effect of treatment may be affected if this medicine is taken at the same time as other medicines for:

  • high blood pressure (thiazide diuretics)
  • heart problems (cardiac glycosides such as digoxin)
  • high cholesterol (cholestyramine)
  • constipation (laxatives such as liquid paraffin)
  • epilepsy (phenytoin or barbiturates)
  • inflammatory diseases/immunosuppression (corticosteroids)
  • obesity (orlistat).

Please make sure your doctor knows if you are taking any of the medicines listed above. Your dose may need to be adjusted.

If you take at the same time a medicine for

  • osteoporosis (bisphosphonates)

you should take it at least one hour before taking Cadelius D.

If you are taking at the same time medicines for

  • infections (quinolones)

you should take them two hours before or six hours after taking Cadelius D.

If you take at the same time medicines for

  • infections (tetracyclines)

you should take them two hours before or six hours after taking Cadelius D.

If you take at the same time medicines for

  • dental caries (sodium fluoride)
  • anemia (iron)

you should take these medicines at least three hours before taking Cadelius D.

If you take at the same time medicines for

  • hypothyroidism (levothyroxine)

you should take Cadelius D at least four hours apart.

Taking Cadelius D with food, drinks, and alcohol

The absorption of calcium may be inhibited by foods containing oxalic acid (present in spinach and rhubarb) or phytic acid (present in whole grains). You should wait at least two hours before taking Cadelius D if you have taken foods with high oxalic acid or phytic acid content.

Pregnancy, breastfeeding, and fertility

During pregnancy, the daily intake should not exceed 1,500 mg of calcium and 600 IU of vitamin D. Therefore, it is not recommended to take Cadelius D during pregnancy.

Cadelius D can be taken during breastfeeding. Calcium and vitamin D3 pass into breast milk. This should be taken into account when vitamin D is additionally administered to the infant.

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before taking this medicine.

Driving and using machines

No effects on the ability to drive and use machines have been observed.

Cadelius D contains aspartame

This medicine contains 8.67 mg of aspartame in each tablet. Aspartame is a source of phenylalanine that may be harmful in people with phenylketonuria (PKU), a rare genetic disorder in which phenylalanine accumulates because the body cannot eliminate it properly.

Cadelius D contains lactose and sucrose.

If your doctor has told you that you have an intolerance to some sugars, consult them before taking this medicine. It may damage teeth.

3. How to take Cadelius D

Follow exactly the administration instructions of this medicine given by your doctor or pharmacist. If you are in doubt, consult your doctor or pharmacist again.

The dose is established by your doctor individually.

The recommended dose is 1 tablet per day.

The tablets should be dissolved in the mouth. They should not be swallowed whole.

The tablets should be taken preferably after meals.

The amount of calcium in Cadelius D is less than the daily intake usually recommended. Cadelius D is therefore recommended in patients who need an additional intake of vitamin D, but with a daily intake of 500-1,000 mg of calcium per day. The dose of calcium recommended for you should be established by your doctor.

Use in children and adolescents

Cadelius D is not indicated in children and adolescents.

If you take more Cadelius D than you should

If you have taken more Cadelius D than you should, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone 91 562 04 20, indicating the medicine and the amount taken.

The symptoms of an overdose of Cadelius D may include loss of appetite, thirst, abnormal emission of large amounts of urine, nausea, vomiting, and constipation.

If you forget to take Cadelius D

Take it as soon as you remember. Then take the next dose as usual. However, if it is already time for your next dose, skip the missed dose and continue as usual. Do not take a double dose to make up for the missed doses.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

You must stop taking Cadelius D and inform your doctor immediately if you experience symptoms of severe allergic reactions such as:

  • Swelling of the face, lips, tongue, or throat
  • Difficulty swallowing
  • Hives and difficulty breathing

Uncommon side effects (may affect up to 1 in 100 people):hypercalcemia (elevated calcium levels in serum) and/or hypercalciuria (elevated calcium levels in urine).

Rare side effects (may affect up to 1 in 1,000 people):constipation, flatulence, nausea, abdominal pain, diarrhea, pruritus, rash, and urticaria.

Side effects with unknown frequency (frequency cannot be estimated from the available data):severe allergic reactions.

Other special populations

Patient with renal insufficiency could have a potential risk of hyperphosphatemia, nephrolithiasis, and nephrocalcinosis

Reporting of side effects

If you experience any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storing Cadelius D

Keep this medicine out of the sight and reach of children.

Keep the container tightly closed.

Do not use this medicine after the expiry date which is stated on the container after EXP. The expiry date is the last day of the month shown.

Store in the original package to protect from light. Keep the container tightly closed to protect from moisture.

The shelf life after first opening is 60 days.

Do not use this medicine if you notice any visible signs of deterioration.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help protect the environment.

6. Contents of the pack and other information

Composition of Cadelius D

  • The active substances are calcium carbonate and colecalciferol (vitamin D3). Each tablet contains 1,500 mg of calcium carbonate equivalent to 600 mg of calcium and 1,000 IU of colecalciferol equivalent to 0.025 mg.
  • The other ingredients are: maltodextrin, aspartame (E951), low-substituted hydroxypropylcellulose (E463), lactose monohydrate, anhydrous citric acid (E330), orange flavor, stearic acid, all-rac-α-tocopherol (E307), partially hydrogenated soybean oil, gelatin, sucrose, corn starch, silicon dioxide.

Appearance and packaging

Cadelius D is presented in the form of white or almost white, circular, beveled oral dispersible tablets.

Bottles of 30 or 60 tablets.

Not all pack sizes may be marketed.

Marketing authorization holder

ITALFARMACO, S.A.

C/ San Rafael, 3

28108 Alcobendas, Madrid

Spain

Manufacturer

ITALFARMACO, S.p.A.

Viale Fulvio Testi 330

20126 Milan

Italy

You can obtain further information on this medicine by contacting the local representative of the marketing authorization holder

Especialidades Farmacéuticas Centrum, S.A.

C/ Sagitario 14

03006 Alicante

Spain

This medicine is authorized in the Member States of the European Economic Area under the following names

Spain Cadelius D 600 mg/1,000 UI oral dispersible tablets

France Cadelius 600 mg/1,000 UI orodispersible tablets

Italy Riliscal 600 mg/1,000 UI orodispersible tablets

Portugal Riliscal 600 mg + 1,000 UI orodispersible tablets

Greece Cadelius 600 mg + 1,000 IU oral dispersible tablets

Date of last revision of this leaflet:January 2022

Updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) (http://www.aemps.gob.es).

Online doctors for CADELIUS D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS

Discuss questions about CADELIUS D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Joao Silva

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Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

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Lisa Drigo

Paediatrics 34 years exp.

Dr Lisa Drigo is an experienced paediatrician based in Italy with over 30 years of clinical practice. She graduated from Università Cattolica del Sacro Cuore in Rome and has spent decades working within the Italian healthcare system, supporting children and families with both acute care and long-term prevention.

She is well familiar with Italian paediatric standards, including local vaccination schedules, preventive check-ups, growth monitoring, and everyday medical issues faced by families living in Italy. This makes her consultations especially valuable for parents who want guidance that aligns with local medical practice.

Her primary focus is paediatrics, with additional support in family medicine when a child’s health needs to be assessed in a broader family or preventive context.

Patients most often consult her for:

  • Acute infections in children (fever, cough, sore throat, runny nose).
  • Viral and bacterial illnesses, frequent colds.
  • Digestive symptoms such as abdominal pain, nausea, diarrhoea or constipation.
  • Monitoring of growth, weight, and developmental milestones.
  • Vaccination advice according to Italian schedules.
  • Allergic reactions, skin rashes, food sensitivities.
  • General health concerns and everyday questions from parents.
  • Preventive care, nutrition advice, and healthy lifestyle guidance.

Dr Drigo communicates in a clear, calm, and reassuring way, helping parents understand what is happening and what steps to take next. Online consultations allow families to receive reliable paediatric guidance aligned with Italian medical practice, without unnecessary stress or waiting.

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Bulat Garipov

General medicine 15 years exp.

Dr. Bulat Garipov is a radiologist with more than 15 years of experience, specializing in magnetic resonance imaging (MRI). Throughout his professional career, he has worked in leading diagnostic imaging centers, both in on-site practice and teleradiology, which has allowed him to develop a broad and versatile approach to radiology.

Over the years, he has gained solid experience in interpreting MRI studies in various areas, including:

  •  Neuroimaging
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  •  Angiography
  •  Abdomen and pelvis
  •  Soft tissues

Additionally, Dr. Garipov is open to new collaboration opportunities in radiology and teleradiology projects. He offers his expertise in MRI, providing both first and second readings of studies, as well as advanced image interpretation, ensuring accurate and high-quality diagnostics.

You could consult Dr. Bulat Garipov in cases where accurate interpretation of MRI studies or a second expert opinion is required. His expertise is especially valuable in cases of suspected neurological conditions, back and joint pain, vascular disorders, as well as in the diagnosis of abdominal and pelvic diseases. The doctor also provides support in complex or unclear clinical situations, including the review of previously performed studies, which helps improve diagnostic accuracy and determine the optimal treatment strategy. A teleradiology format is available, allowing you to receive a professional opinion remotely.

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Giorgi Eremeishvili

Urology 22 years exp.

Giorgi Eremeishvili is a top-category urologist, a Candidate of Medical Sciences, and a licensed physician in Spain. He provides expert assistance in the diagnosis and treatment of a wide range of urological conditions in both men and women, employing a comprehensive approach and evidence-based principles.

Key areas of expertise:

  • Erectile dysfunction, decreased libido, premature ejaculation.
  • Male infertility: comprehensive diagnosis and modern treatment methods.
  • Prostate gland diseases: acute and chronic prostatitis, prostatic adenoma (benign prostatic hyperplasia), prostate cancer.
  • Inflammatory diseases of the genitourinary system: acute and chronic cystitis, pyelonephritis, epididymitis, orchitis, urethritis.
  • Sexually transmitted infections (STIs): chlamydia, ureaplasmosis, mycoplasmosis, gardnerellosis, candidiasis, herpetic infections, HPV, CMV, trichomoniasis, and others.
  • Urination disorders: urinary retention, frequent urination, urinary incontinence, overactive bladder, neurogenic bladder.
  • Neoplasms: cysts, tumors of the kidneys, bladder, testicles, prostate gland (including prostate cancer).
  • Surgical interventions: determining indications and selecting optimal minimally invasive methods.

Dr. Eremeishvili applies an integrated approach to each case. This includes thorough preoperative preparation, postoperative observation, and regular dynamic follow-up during the treatment process to achieve the best possible outcomes. All diagnostic and therapeutic recommendations are based on current evidence-based medicine and comply with the recommendations of the European Association of Urology, guaranteeing high-quality and effective care.

If you are seeking qualified assistance in diagnosing or treating urological conditions, book an online consultation with Dr. Giorgi Eremeishvili. Get expert support, accurate diagnosis, and a personalized treatment plan from the comfort of your home.

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Daria Portnova

Psychiatry 31 years exp.

Dr Daria Portnova is a psychiatrist and psychotherapist with over 30 years of clinical experience. She works with adults and adolescents aged 14 and over, providing online psychiatric and psychotherapeutic consultations. In her practice, Dr Portnova supports patients facing the onset of mental health conditions, chronic psychiatric disorders, psychotic symptoms, trauma-related states, and complex emotional crises. Her work is structured and safety-focused, with an emphasis on stabilisation, accurate diagnosis, and long-term improvement in quality of life. Patients consult Dr Daria Portnova for the following concerns: 

  • existential crises and complex life situations;
  • loss, grief, and emotional exhaustion;
  • relationship difficulties, separation, and divorce;
  • psychological and psychiatric trauma, including complex PTSD (cPTSD);
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  • social anxiety and social phobia;
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  • sleep disorders;
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  • bipolar affective disorder;
  • schizoaffective disorder;
  • schizophrenia;
  • personality disorders.

Dr Portnova combines psychiatric assessment with a psychotherapeutic approach. She works with evidence-based methods, including cognitive behavioural therapy (CBT) and third-wave approaches such as ACT, FACT, and CFT. Consultations are focused on clear clinical understanding, practical recommendations, and ongoing support over time.

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Frequently Asked Questions

Is a prescription required for CADELIUS D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS?
CADELIUS D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
How much does CADELIUS D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS cost in pharmacies?
The average pharmacy price for CADELIUS D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS is around 9.01 EUR. Prices may vary depending on the manufacturer and dosage form.
Who manufactures CADELIUS D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS?
CADELIUS D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS is manufactured by Italfarmaco S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of CADELIUS D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether CADELIUS D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to CADELIUS D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS?
Other medicines with the same active substance () include ADIAVAL 1000 mg/880 IU CHEWABLE TABLETS, BONESIL D FLAS 1500 mg/400 IU ORALLY DISINTEGRATING TABLETS, CADELIUS D 600 MG/2000 IU ORALLY DISINTEGRATING TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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