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BRONSAL Injectable Solution

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About the medicine

How to use BRONSAL Injectable Solution

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Bronsal Injectable Solution

(Betamethasone, Diprophylline, Guaifenesin)

Read the entire package leaflet carefully before starting to take this medication, as it contains important information for you.

  • Keep this package leaflet, as you may need to read it again.
  • If you have any questions, consult your doctor or pharmacist.
  • This medication has been prescribed to you only, and you should not give it to others, even if they have the same symptoms as you, as it may harm them.
  • If you experience side effects, consult your doctor or pharmacist, even if they are not listed in this package leaflet. See section 4.

Contents of the Package Leaflet

  1. What is Bronsal Injectable Solution and what is it used for
  2. What you need to know before taking Bronsal Injectable Solution
  3. How to use Bronsal Injectable Solution
  4. Possible side effects
  5. Storage of Bronsal Injectable Solution
  6. Package Contents and Additional Information

1. What is Bronsal Injectable Solution and what is it used for

Bronsal Injectable Solution contains the active ingredients betamethasone, diprophylline, and guaifenesin.

It is indicated in the acute phase of respiratory diseases that compromise adequate pulmonary ventilation.

This medication is designed for the symptomatic treatment of these acute processes, which should resolve within a short period (6-10 days). In chronic diseases, specific treatment should be continued.

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2. What you need to know before taking Bronsal Injectable Solution

Do not use Bronsal Injectable Solution

  • If you are allergic to betamethasone, diprophylline, guaifenesin, or any other component of this medication (listed in section 6).
  • If you have a fungal infection.
  • If you have been diagnosed with idiopathic thrombocytopenic purpura (a blood disease characterized by a lack of platelets).
  • If you have severe liver or kidney failure.
  • In children under 2 years of age.

Warnings and Precautions

Consult your doctor or pharmacist before taking Bronsal Injectable Solution if you are in any of the following situations:

  • Uremic patients (uremia is the concentration in the blood of waste products that are normally eliminated by the kidneys).
  • Whenever there is or is suspected to be an infectious process. Your doctor will prescribe oral or parenteral antibiotics.
  • If the recommended treatment periods are exceeded, the side effects of systemic corticosteroids may appear.
  • Elderly patients.
  • Patients with a history of tuberculosis.
  • Patients with severe myocardial or coronary lesions, or severe hypertension.
  • Patients with hyperthyroidism.
  • Patients with liver or kidney disease.
  • Patients with diabetes mellitus.
  • Patients with gastric ulcers.
  • Patients with osteoporosis.
  • Patients with epilepsy.
  • Patients with myasthenia gravis (a chronic autoimmune neuromuscular disease characterized by variable degrees of weakness of the skeletal muscles).
  • Patients with glaucoma (an eye disease in which the optic nerve is damaged).
  • If you experience blurred vision or other visual disturbances.
  • If you have pheochromocytoma (a tumor of the adrenal gland).

This medication contains betamethasone, which may produce a positive result in doping tests.

Using Bronsal Injectable Solution with Other Medications

Tell your doctor or pharmacist if you are using, have recently used, or may need to use any other medication, including those purchased without a prescription.

The following medications may interact with Bronsal. Inform your doctor if you are taking any of them:

  • Xanthine-type medications (e.g., theophylline), as they may enhance the effect of Bronsal.
  • Probenecid (a medication used to treat gout).
  • Medications that induce liver enzymes (barbiturates, phenytoin, and rifampicin).
  • Enzyme inhibitors (CYP3A4) such as ketoconazole and itraconazole (used for fungal infections) may increase the effect of corticosteroids. Therefore, your doctor will closely monitor you if you are taking these medications (including some for HIV: ritonavir, cobicistat).
  • Aspirin (salicylates). Caution should be exercised if Bronsal is used concomitantly with salicylates in patients with hypoprothrombinemia (deficiency of a substance necessary for blood coagulation).
  • Diuretics that increase potassium elimination.
  • Isoproterenol (a medication used to treat asthma).

Pregnancy and Breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medication.

The use of this medication is not recommended during pregnancy and breastfeeding, except on explicit medical indication.

Newborns of mothers who received betamethasone near the end of pregnancy may have low blood sugar levels after birth.

Driving and Using Machines

Not described.

This medication contains sodium, methylparaben, propylparaben, and sodium metabisulfite.

It may cause allergic reactions (possibly delayed) and, exceptionally, bronchospasm (sudden feeling of suffocation) because it contains methylparaben and propylparaben.

It may cause severe allergic reactions or bronchospasm (sudden feeling of suffocation) because it contains sodium metabisulfite.

This medication contains less than 23 mg (1 mmol) of sodium per dose, so it is considered essentially "sodium-free".

3. How to Use Bronsal Injectable Solution

Follow your doctor's instructions for administering Bronsal exactly. Consult your doctor or pharmacist if you have any questions.

The recommended dose in adults is one injection every 12-24 hours via intramuscular route.

If you use more Bronsal Injectable Solution than you should

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone 91 562 04 20, indicating the medication and the amount ingested.

If you forget to use Bronsal Injectable Solution

Do not use a double dose to make up for forgotten doses.

If you have any other questions about using this medication, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible Side Effects

Like all medications, Bronsal can cause side effects, although not everyone will experience them.

The severity of side effects associated with prolonged treatment increases with the dose and duration of treatment. Short-term treatments usually do not produce adverse reactions.

Frequent (may affect 1 to 10 in every 100 patients): gastrointestinal disorders (nausea, vomiting, abdominal pain, diarrhea), headache, excitement, insomnia or drowsiness, osteoporosis, bone fragility, hyperglycemia, polyphagia (abnormal increase in the need to eat), delayed wound healing, propensity to infections (oropharyngeal candidiasis), signs of adrenal hyperactivity (Cushing's syndrome), hirsutism (excessive hair growth in women, on the face and body), skin hyperpigmentation, gastric ulcers.

Uncommon (may affect 1 to 10 in every 1,000 patients): edema (swelling), hypertension, heart failure, hypokalemia (decreased potassium levels), amenorrhea (temporary or permanent absence of menstrual flow), sweating, neurological disorders, intracranial hypertension, acute pancreatitis, thromboembolism, myasthenia (a chronic autoimmune neuromuscular disease characterized by variable degrees of weakness of the skeletal muscles).

Frequency unknown: hypoaesthesia, blurred vision (see also section 4.4).

If you experience side effects, consult your doctor or pharmacist, even if they are not listed in this package leaflet.

5. Storage of Bronsal Injectable Solution

No special storage conditions are required.

Keep this medication out of sight and reach of children.

Do not use this medication after the expiration date stated on the packaging after CAD. The expiration date is the last day of the month indicated.

Medications should not be disposed of through wastewater or household waste. Deposit the packaging and any unused medication in the pharmacy's SIGRE point. If in doubt, ask your pharmacist how to dispose of the packaging and any unused medication. This will help protect the environment.

6. Package Contents and Additional Information

Composition of Bronsal Injectable Solution

The active ingredients are (per 4 ml ampoule): betamethasone 2 mg (betamethasone phosphate and sodium), diprophylline 250 mg, and guaifenesin 200 mg.

The other ingredients are: sodium metabisulfite (E-223), disodium edetate, anhydrous disodium hydrogen phosphate, methylparaben (E-218), propylparaben (E-216), and water for injectable preparations.

Appearance of the Product and Package Contents

Bronsal is a clear and colorless solution. Each package contains 5 ampoules of 4 ml.

Marketing Authorization Holder and Manufacturer

Holder

IONFARMA, S.L.U.

Perú, 228

08020 Barcelona, Spain.

Manufacturer

LABORATORIOS REIG JOFRÉ, S.A.

Gran Capitán, 10

08970 Sant Joan Despí, Barcelona, Spain.

Date of the Last Revision of this Package Leaflet:April 2022.

Detailed and updated information on this medication is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for BRONSAL Injectable Solution

Discuss questions about BRONSAL Injectable Solution, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Svetlana Kolomeeva

Cardiology 18 years exp.

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

  • High blood pressure, headaches, dizziness, swelling, palpitations.
  • Diagnosis and management of hypertension, arrhythmias, and tachycardia.
  • Metabolic syndrome, excess weight, high cholesterol.
  • Chronic fatigue, insomnia, poor concentration, anxiety.
  • Respiratory symptoms: colds, flu, sore throat, cough, fever.
  • Digestive issues: heartburn, bloating, constipation, IBS symptoms.
  • Chronic conditions: diabetes, thyroid disorders.
  • Interpretation of lab tests and medical reports, therapy adjustment.
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  • Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

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Anna Biriukova

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Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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Alina Tsurkan

Family medicine 13 years exp.

Dr. Alina Tsurkan is a licensed family medicine physician based in Portugal, offering online consultations for adults and children. She provides professional primary care, with a focus on prevention, accurate diagnosis, and long-term management of acute and chronic conditions.

Dr. Tsurkan supports patients with a wide range of health issues, including:

  • Respiratory infections: cold, flu, bronchitis, pneumonia, and lingering coughs.
  • ENT conditions: sinusitis, tonsillitis, otitis (ear infections), sore throat, allergic rhinitis.
  • Eye conditions: allergic or infectious conjunctivitis, red eyes, irritation.
  • Digestive issues: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), constipation, bloating, nausea.
  • Urinary and reproductive health: urinary tract infections (UTIs), cystitis, prevention of recurrent infections.
  • Chronic diseases: hypertension, elevated cholesterol, weight management.
  • Neurological complaints: headaches, migraines, sleep disturbances, fatigue, general weakness.
  • Children’s health: fever, infections, digestive issues, follow-ups, vaccination guidance.

She also provides:

  • IMT medical certificates for driving licence exchange in Portugal.
  • Personalised preventive care and wellness consultations.
  • Interpretation of test results and medical reports.
  • Follow-up care and medication review.
  • Support in managing multiple coexisting conditions.
  • Remote prescription management and medical documentation.

Dr. Tsurkan’s approach is evidence-based and holistic. She works closely with each patient to develop an individualised care plan that addresses both symptoms and root causes. Her goal is to empower patients to take control of their health and maintain well-being through lifestyle adjustments, routine check-ups, and early intervention.

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Doctor

Maria Martelli

Anaesthesiology 12 years exp.

Dr Maria Martelli is a medical doctor specialising in anaesthesiology and pain medicine. She provides online consultations for adults, focusing on the assessment and management of acute, chronic, and complex pain conditions, as well as supportive care in serious illness. She graduated from the Medical University of Silesia in Katowice and completed her specialisation in Anaesthesiology and Intensive Care. Alongside hospital work, she has extensive experience in home and inpatient hospice care, supporting patients with severe pain and advanced disease. Since 2021, she has been a certified specialist and continues to work in anaesthesiology, intensive care, and pain treatment. Patients consult her for: 

  • Chronic pain lasting more than 3 months (musculoskeletal, neuropathic, mixed pain).
  • Acute pain requiring medical assessment and treatment planning.
  • Post-operative pain and recovery support.
  • Cancer-related pain and symptom relief.
  • Palliative care support and quality-of-life improvement.
  • Adjustment and optimisation of pain medication.
  • Second opinions for complex or treatment-resistant pain.

Dr Martelli takes a structured, evidence-based approach, carefully analysing symptoms, previous treatments, and overall health status. Her consultations focus on realistic pain control goals, safety of therapy, and improving daily functioning. She is especially attentive to patients living with long-term pain or serious illness, providing clear explanations, compassionate guidance, and medically sound recommendations adapted to each individual situation.

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Doctor

Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
  • Structured support for undiagnosed complaints.
  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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Frequently Asked Questions

Is a prescription required for BRONSAL Injectable Solution?
BRONSAL Injectable Solution requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in BRONSAL Injectable Solution?
The active ingredient in BRONSAL Injectable Solution is diprophylline, combinations. This information helps identify medicines with the same composition but different brand names.
Who manufactures BRONSAL Injectable Solution?
BRONSAL Injectable Solution is manufactured by Ionfarma S.L.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of BRONSAL Injectable Solution online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether BRONSAL Injectable Solution is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to BRONSAL Injectable Solution?
Other medicines with the same active substance (diprophylline, combinations) include ELIXIFILIN 5.33 mg/ml ORAL SOLUTION, FLUIDASA 150 mg HARD CAPSULES, FLUIDASA 20 mg/ml ORAL DROPS IN SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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