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BILINA 0.5 mg/ml EYE DROPS IN SUSPENSION

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About the medicine

How to use BILINA 0.5 mg/ml EYE DROPS IN SUSPENSION

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Leaflet: information for the user

Bilina 0.5 mg/ml eye drops in suspension

Levocabastina

Read this leaflet carefully before starting to use this medication, as it contains important information for you.

  • Keep this leaflet, as you may need to read it again.
  • If you have any doubts, consult your doctor or pharmacist.
  • This medication has been prescribed to you only, and you should not give it to others, even if they have the same symptoms as you, as it may harm them.
  • If you experience side effects, consult your doctor or pharmacist, even if they are not listed in this leaflet. See section 4.

Contents of the leaflet

  1. What is Bilina and what is it used for
  2. What you need to know before using Bilina
  3. How to use Bilina
  4. Possible side effects
  5. Storage of Bilina
  6. Package contents and additional information

1. What is Bilina and what is it used for

Bilina 0.5 mg/ml eye drops in suspension contain levocabastina, which is an antihistamine used for the symptomatic treatment of allergic conjunctivitis in adults and in children and adolescents from 4 to less than 18 years of age.

Levocabastina is a highly selective antagonist of histamine H1 receptors. After application to the eyes, it provides rapid and long-lasting relief from the symptoms of allergic conjunctivitis (itching, redness, eyelid inflammation, tearing).

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2. What you need to know before using Bilina

Do not use Bilina

  • If you are allergic (hypersensitive) to levocabastina or any of the other components of this medication (listed in section 6).

Warnings and precautions

Consult your doctor or pharmacist before starting to use Bilina.

Children and adolescents

  • The safety and efficacy of this medication have not been established in children under 4 years of age.
  • Bilina should only be used to treat children and adolescents from 4 to less than 18 years of age.

Using Bilina with other medications

No interactions have been described.

Tell your doctor or pharmacist if you are using, have recently used, or might use any other medication.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you might be pregnant, or plan to become pregnant, do not use Bilina, as safety studies have not been conducted in pregnant women, and Bilina passes into breast milk. Consult your doctor or pharmacist before using this medication.

Driving and using machines

Bilina does not cause sedation or interfere with psychomotor activity. Adverse reactions with Bilina eye drops, such as eye irritation, pain, swelling, itching, redness, burning sensation, tearing, or blurred vision, have been reported, which may affect vision. Therefore, caution is recommended when driving or operating machinery after applying Bilina eye drops.

Bilina eye drops contain benzalkonium chloride

This medication contains 15 mg of benzalkonium chloride per ml.

Benzalkonium chloride can be absorbed by soft contact lenses, altering their color. Remove contact lenses before using this medication and wait 15 minutes before putting them back in.

Benzalkonium chloride can cause eye irritation, especially if you have dry eye or other corneal diseases (the transparent layer on the front of the eye). Consult your doctor if you feel any unusual sensation, itching, or pain in the eye after using this medication.

This medication contains 14.04 mg of phosphates per ml.

If you have severe corneal damage (the transparent layer on the front of the eye), treatment with phosphates, in very rare cases, may cause blurred vision due to calcium accumulation.

3. How to use Bilina

  1. Dosage

Follow your doctor's instructions for administering this medication exactly. If you have any doubts, consult your doctor or pharmacist again.

Adults and children and adolescents from 4 to less than 18 years of age

The recommended dose is 1 drop of Bilina per eye, 2 times a day. The dose can be increased to 1 drop in each eye, 3 or 4 times a day. Treatment should continue until symptoms disappear.

Use in children under 4 years of age

The safety and efficacy of this medication have not been established. No data are available.

Elderly

No data are available on the use of levocabastina in the elderly.

  1. Instructions for use

Before the first use of Bilina, remove the seal from the container and note the opening date on the box.

Follow these steps:

  1. Shake the container well before removing the cap
  2. Tilt your head back as far as possible
  3. Press the bottle and carefully pour 1 drop into the inner corner of the eye. Pull the lower eyelid down while keeping your head tilted back, so the drops can reach the area between the eye and the eyelid. Try to blink to spread the drops across the entire eye.
  4. Needle inserted into the skin at a 45-degree angle held with two fingersRepeat step 3 for the other eye.

Do not touch the bottle to the eye to avoid introducing impurities into the remaining liquid. Do not use the drops for more than 1 month after opening the bottle for the first time.

Treatment should continue until symptoms improve.

If you use more Bilina than you should

If you accidentally drink the contents of a container, you may feel drowsy. In this case, it is recommended to drink plenty of non-alcoholic liquids to accelerate the elimination of the medication through the kidneys and contact your doctor immediately.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone: 91 562 04 20, indicating the medication and the amount ingested.

If you forget to use Bilina

Do not apply an extra drop to the eye to make up for the missed dose.

If you have any other doubts about using this product, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medications, Bilina can cause side effects, although not everyone will experience them.

The frequency of the possible side effects listed below is defined using the following convention:

Very common (may affect more than 1 in 10 people)

Common (may affect up to 1 in 10 people)

Uncommon (may affect up to 1 in 100 people)

Rare (may affect up to 1 in 1,000 people)

Very rare (may affect up to 1 in 10,000 people)

Frequency not known (cannot be estimated from the available data)

The side effects observed with Bilina are:

Common side effects (affecting between 1 and 10 in 100 patients) may include:

  • Reaction at the site of administration, such as burning/stinging in the eyes, eye irritation

Very rare side effects (affecting less than 1 in 10,000 patients) may include:

  • A particular type of allergic reaction characterized by swelling of the lips, tongue, eyelids (angioedema) or other allergic reactions (anaphylaxis, hypersensitivity), such as hives and difficulty breathing
  • Eye pain
  • Conjunctivitis
  • Eyelid swelling
  • Eye swelling
  • Eyelid inflammation
  • Eye congestion
  • Reaction at the site of administration, such as redness, itching in the eyes
  • Skin irritation in the area in contact with the medication
  • Hives
  • Headache
  • Palpitations

If you experience side effects, consult your doctor or pharmacist, even if they are not listed in this leaflet.

Reporting side effects:

If you experience any type of side effect, consult your doctor or pharmacist, even if it is a possible side effect that is not listed in this leaflet. You can also report them directly through the Spanish Medication Surveillance System for Human Use: https://www.notificaram.es. By reporting side effects, you can contribute to providing more information on the safety of this medication.

5. Storage of Bilina

Keep out of sight and reach of children.

Do not use this medication after the expiration date stated on the container after CAD. The expiration date is the last day of the month indicated.

Discard 28 days after the first opening of the container.

Do not store above 25°C.

Medications should not be disposed of through wastewater or household waste. Deposit the containers and medications you no longer need at the pharmacy's SIGRE point. If you have any doubts, ask your pharmacist how to dispose of the containers and medications you no longer need. This will help protect the environment.

6. Package contents and additional information

Composition of Bilina

  • The active ingredient is levocabastina. Each milliliter of Bilina contains 0.5 milligrams of levocabastina.
  • The other components (excipients) are benzalkonium chloride, propylene glycol, anhydrous disodium phosphate, monosodium phosphate, hypromellose, polysorbate 80, disodium edetate, and water for injectable preparations.

Appearance of the product and package contents

Bilina is presented as a sterile eye drop suspension, white in color, in a 4 ml plastic dropper bottle.

Marketing authorization holder and manufacturer

Marketing authorization holder

Esteve Pharmaceuticals, S.A.

Passeig de la Zona Franca, 109

08038 Barcelona

Spain

Manufacturer

Famar, S.A.

Agiou Dimitriou 63

Alimos Attiki

17456 Greece

Date of the last revision of this leaflet: September 2020

Detailed and updated information on this medication is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/.

Online doctors for BILINA 0.5 mg/ml EYE DROPS IN SUSPENSION

Discuss questions about BILINA 0.5 mg/ml EYE DROPS IN SUSPENSION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (5)
Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

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Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
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  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Doctor

Joao Silva

General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

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Doctor

Bulat Garipov

General medicine 15 years exp.

Dr. Bulat Garipov is a radiologist with more than 15 years of experience, specializing in magnetic resonance imaging (MRI). Throughout his professional career, he has worked in leading diagnostic imaging centers, both in on-site practice and teleradiology, which has allowed him to develop a broad and versatile approach to radiology.

Over the years, he has gained solid experience in interpreting MRI studies in various areas, including:

  •  Neuroimaging
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You could consult Dr. Bulat Garipov in cases where accurate interpretation of MRI studies or a second expert opinion is required. His expertise is especially valuable in cases of suspected neurological conditions, back and joint pain, vascular disorders, as well as in the diagnosis of abdominal and pelvic diseases. The doctor also provides support in complex or unclear clinical situations, including the review of previously performed studies, which helps improve diagnostic accuracy and determine the optimal treatment strategy. A teleradiology format is available, allowing you to receive a professional opinion remotely.

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Frequently Asked Questions

Is a prescription required for BILINA 0.5 mg/ml EYE DROPS IN SUSPENSION?
BILINA 0.5 mg/ml EYE DROPS IN SUSPENSION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in BILINA 0.5 mg/ml EYE DROPS IN SUSPENSION?
The active ingredient in BILINA 0.5 mg/ml EYE DROPS IN SUSPENSION is levocabastine. This information helps identify medicines with the same composition but different brand names.
How much does BILINA 0.5 mg/ml EYE DROPS IN SUSPENSION cost in pharmacies?
The average pharmacy price for BILINA 0.5 mg/ml EYE DROPS IN SUSPENSION is around 7.73 EUR. Prices may vary depending on the manufacturer and dosage form.
Who manufactures BILINA 0.5 mg/ml EYE DROPS IN SUSPENSION?
BILINA 0.5 mg/ml EYE DROPS IN SUSPENSION is manufactured by Esteve Pharmaceuticals S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of BILINA 0.5 mg/ml EYE DROPS IN SUSPENSION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether BILINA 0.5 mg/ml EYE DROPS IN SUSPENSION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to BILINA 0.5 mg/ml EYE DROPS IN SUSPENSION?
Other medicines with the same active substance (levocabastine) include REACTINE LEVOCABASTINE 0.5mg/ml EYE DROPS, SUSPENSION, AFLUON 0.5 mg/ml EYE DROPS SOLUTION, APADIN 1 mg/ml EYE DROPS SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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