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ANTICUDE

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use ANTICUDE

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

ANTICUDE 25mg/2ml ampoules

Edrophonium Bromide

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again. If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack

  1. What Anticude is and what it is used for
  2. What you need to know before you use Anticude
  3. How to use Anticude
  4. Possible side effects
  5. Storing Anticude
  6. Contents of the pack and other information

1. What Anticude is and what it is used for

Anticude is a medicine used as an antidote for curarizing agents, including synthetic ones, in prolonged apnea and in any syndrome that involves atony of striated or smooth muscle.

It is also used for the diagnosis and treatment of myasthenia gravis and to facilitate the differential diagnosis of arrhythmias due to digitalis intoxication.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you use Anticude

Do not use Anticude

If you are allergic (hypersensitive) to Edrophonium bromide or any of the other ingredients of Anticude.

Take special care with Anticude

In hyperadrenergic states.

Using other medicines

Tell your doctor or pharmacist if you are using or have recently used any other medicines, including those obtained without a prescription.

No interactions with other medicines have been described for Anticude.

The use of Anticude is incompatible with any sympathomimetic or anticholinergic agent.

Pregnancy and breastfeeding

Consult your doctor or pharmacist before using any medicine.

Important information about some of the ingredients of Anticude

This medicine contains Sodium Bisulfite (E-222), which may cause severe allergic reactions and bronchospasm (sudden feeling of suffocation) because it contains 0.8mg per ampoule.

This medicine contains less than 23mg (1mmol) of sodium per ampoule, so it is considered essentially "sodium-free".

3. How to use Anticude

Follow exactly the administration instructions of Anticude indicated by your doctor. Consult your doctor or pharmacist if you have doubts.

Although the average dose as an antidote for miorelaxants is 1 to 3 ampoules, it varies according to the clinician's criteria, the patient's idiosyncrasy, and the type of curarizing agent whose action is to be antagonized.

Anticude is administered exclusively by the intravenous route.

If you use more Anticude than you should

Consult your doctor, pharmacist, or call the Toxicology Information Service, phone 91 562 04 20, indicating the medicine and the amount used.

If you forget to use Anticude

Do not use a double dose to make up for forgotten doses.

If you have any other questions about the use of this product, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, Anticude can cause side effects, although not everybody gets them.

No side effects are known, and it is also exempt from the secondary effects inherent to most cholinesterase inhibitors, such as hypotension, salivation, etc., which should be avoided in the post-operative patient.

No cases of clinical intoxication due to Edrophonium effects have been described. However, if this incidence occurs, drugs with antagonistic action should be administered, i.e., sympathomimetics or anticholinergics.

If you think any of the side effects you are suffering from is serious, or if you notice any side effect not mentioned in this leaflet, tell your doctor or pharmacist.

5. Storing Anticude

No special storage conditions are required.

Keep out of the reach and sight of children.

Do not use Anticude after the expiry date stated on the packaging after CAD. The expiry date is the last day of the month indicated.

Do not use Anticude ampoules if you notice visible signs of deterioration.

Dispose of the packaging and any unused medicine in the SIGRE collection point at the pharmacy. If in doubt, ask your pharmacist how to dispose of the packaging and any unused medicine. This will help protect the environment.

6. Contents of the pack and other information

Composition of Anticude

  • The active ingredient is Edrophonium bromide. Each 2mL ampoule contains 25mg of Edrophonium bromide.
  • The other ingredients are: Sodium Chloride, Sodium Bisulfite, and Water for Injection.

Appearance of the product and contents of the pack

Box with 2 ampoules of 2mL.

Marketing Authorisation Holder:

MANA PHARMA, S.L.

Carr. Fuencarral 22

Alcobendas 28108

(Madrid) Spain

Phone: 910 68 44 50

Manufacturer:

  • BRAUN MEDICAL, S.A.

Ronda de los Olivares

Polígono Industrial Los Olivares

Parcela 11

23009, Jaén, Spain

Phone: +34 953 24 98 80

Fax: +34 953 28 13 51

Date of the last revision of this leaflet11/2023

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.es/

Online doctors for ANTICUDE

Discuss questions about ANTICUDE, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (3)
Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

Camera Book a video appointment
€80
5.0 (140)
Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Camera Book a video appointment
€50

Frequently Asked Questions

Is a prescription required for ANTICUDE?
ANTICUDE requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in ANTICUDE?
The active ingredient in ANTICUDE is edrophonium. This information helps identify medicines with the same composition but different brand names.
Who manufactures ANTICUDE?
ANTICUDE is manufactured by Mana Pharma S.L.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of ANTICUDE online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether ANTICUDE is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to ANTICUDE?
Other medicines with the same active substance (edrophonium) include APULCO ACOMETH 0.3%/0.3%/0.3% MEDICINAL COMPRESSED GAS, APULCO COHE 0.28%/9.5% MEDICINAL COMPRESSED GAS, APULCO COHEMAX 0.28%/14% MEDICINAL COMPRESSED GAS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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