ANTICUDE
How to use ANTICUDE
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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.
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Introduction
Package Leaflet: Information for the User
ANTICUDE 25mg/2ml ampoules
Edrophonium Bromide
Read all of this leaflet carefully before you start using this medicine because it contains important information for you.
- Keep this leaflet, you may need to read it again. If you have any further questions, ask your doctor or pharmacist.
- This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
- If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.
Contents of the pack
- What Anticude is and what it is used for
- What you need to know before you use Anticude
- How to use Anticude
- Possible side effects
- Storing Anticude
- Contents of the pack and other information
1. What Anticude is and what it is used for
Anticude is a medicine used as an antidote for curarizing agents, including synthetic ones, in prolonged apnea and in any syndrome that involves atony of striated or smooth muscle.
It is also used for the diagnosis and treatment of myasthenia gravis and to facilitate the differential diagnosis of arrhythmias due to digitalis intoxication.
2. What you need to know before you use Anticude
Do not use Anticude
If you are allergic (hypersensitive) to Edrophonium bromide or any of the other ingredients of Anticude.
Take special care with Anticude
In hyperadrenergic states.
Using other medicines
Tell your doctor or pharmacist if you are using or have recently used any other medicines, including those obtained without a prescription.
No interactions with other medicines have been described for Anticude.
The use of Anticude is incompatible with any sympathomimetic or anticholinergic agent.
Pregnancy and breastfeeding
Consult your doctor or pharmacist before using any medicine.
Important information about some of the ingredients of Anticude
This medicine contains Sodium Bisulfite (E-222), which may cause severe allergic reactions and bronchospasm (sudden feeling of suffocation) because it contains 0.8mg per ampoule.
This medicine contains less than 23mg (1mmol) of sodium per ampoule, so it is considered essentially "sodium-free".
3. How to use Anticude
Follow exactly the administration instructions of Anticude indicated by your doctor. Consult your doctor or pharmacist if you have doubts.
Although the average dose as an antidote for miorelaxants is 1 to 3 ampoules, it varies according to the clinician's criteria, the patient's idiosyncrasy, and the type of curarizing agent whose action is to be antagonized.
Anticude is administered exclusively by the intravenous route.
If you use more Anticude than you should
Consult your doctor, pharmacist, or call the Toxicology Information Service, phone 91 562 04 20, indicating the medicine and the amount used.
If you forget to use Anticude
Do not use a double dose to make up for forgotten doses.
If you have any other questions about the use of this product, ask your doctor or pharmacist.
4. Possible side effects
Like all medicines, Anticude can cause side effects, although not everybody gets them.
No side effects are known, and it is also exempt from the secondary effects inherent to most cholinesterase inhibitors, such as hypotension, salivation, etc., which should be avoided in the post-operative patient.
No cases of clinical intoxication due to Edrophonium effects have been described. However, if this incidence occurs, drugs with antagonistic action should be administered, i.e., sympathomimetics or anticholinergics.
If you think any of the side effects you are suffering from is serious, or if you notice any side effect not mentioned in this leaflet, tell your doctor or pharmacist.
5. Storing Anticude
No special storage conditions are required.
Keep out of the reach and sight of children.
Do not use Anticude after the expiry date stated on the packaging after CAD. The expiry date is the last day of the month indicated.
Do not use Anticude ampoules if you notice visible signs of deterioration.
Dispose of the packaging and any unused medicine in the SIGRE collection point at the pharmacy. If in doubt, ask your pharmacist how to dispose of the packaging and any unused medicine. This will help protect the environment.
6. Contents of the pack and other information
Composition of Anticude
- The active ingredient is Edrophonium bromide. Each 2mL ampoule contains 25mg of Edrophonium bromide.
- The other ingredients are: Sodium Chloride, Sodium Bisulfite, and Water for Injection.
Appearance of the product and contents of the pack
Box with 2 ampoules of 2mL.
Marketing Authorisation Holder:
MANA PHARMA, S.L.
Carr. Fuencarral 22
Alcobendas 28108
(Madrid) Spain
Phone: 910 68 44 50
Manufacturer:
- BRAUN MEDICAL, S.A.
Ronda de los Olivares
Polígono Industrial Los Olivares
Parcela 11
23009, Jaén, Spain
Phone: +34 953 24 98 80
Fax: +34 953 28 13 51
Date of the last revision of this leaflet11/2023
Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.es/
- Country of registration
- Availability in pharmacies
Supply issue reported
Data from the Spanish Agency of Medicines (AEMPS) indicates a supply issue affecting this medicine.<br><br>Availability may be limited in some pharmacies.<br><br>For updates or alternatives, consult your pharmacist. - Active substance
- Prescription requiredYes
- Manufacturer
- This information is for reference only and does not constitute medical advice. Always consult a doctor before taking any medication. Oladoctor is not responsible for medical decisions based on this content.
- Alternatives to ANTICUDEDosage form: PULMONARY INHALATION, 0.3%/0.3%/0.3% mol/molActive substance:Manufacturer: Sociedad Española De Carburos Metalicos S.A.Prescription requiredDosage form: PULMONARY INHALATION, 0.28%/9.5% mol/molActive substance:Manufacturer: Sociedad Española De Carburos Metalicos S.A.Prescription requiredDosage form: PULMONARY INHALATION, 0.28%/14% mol/molActive substance:Manufacturer: Sociedad Española De Carburos Metalicos S.A.Prescription required
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