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BRONSAL Injectable Solution

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use BRONSAL Injectable Solution

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Bronsal Injectable Solution

(Betamethasone, Diprophylline, Guaifenesin)

Read the entire package leaflet carefully before starting to take this medication, as it contains important information for you.

  • Keep this package leaflet, as you may need to read it again.
  • If you have any questions, consult your doctor or pharmacist.
  • This medication has been prescribed to you only, and you should not give it to others, even if they have the same symptoms as you, as it may harm them.
  • If you experience side effects, consult your doctor or pharmacist, even if they are not listed in this package leaflet. See section 4.

Contents of the Package Leaflet

  1. What is Bronsal Injectable Solution and what is it used for
  2. What you need to know before taking Bronsal Injectable Solution
  3. How to use Bronsal Injectable Solution
  4. Possible side effects
  5. Storage of Bronsal Injectable Solution
  6. Package Contents and Additional Information

1. What is Bronsal Injectable Solution and what is it used for

Bronsal Injectable Solution contains the active ingredients betamethasone, diprophylline, and guaifenesin.

It is indicated in the acute phase of respiratory diseases that compromise adequate pulmonary ventilation.

This medication is designed for the symptomatic treatment of these acute processes, which should resolve within a short period (6-10 days). In chronic diseases, specific treatment should be continued.

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2. What you need to know before taking Bronsal Injectable Solution

Do not use Bronsal Injectable Solution

  • If you are allergic to betamethasone, diprophylline, guaifenesin, or any other component of this medication (listed in section 6).
  • If you have a fungal infection.
  • If you have been diagnosed with idiopathic thrombocytopenic purpura (a blood disease characterized by a lack of platelets).
  • If you have severe liver or kidney failure.
  • In children under 2 years of age.

Warnings and Precautions

Consult your doctor or pharmacist before taking Bronsal Injectable Solution if you are in any of the following situations:

  • Uremic patients (uremia is the concentration in the blood of waste products that are normally eliminated by the kidneys).
  • Whenever there is or is suspected to be an infectious process. Your doctor will prescribe oral or parenteral antibiotics.
  • If the recommended treatment periods are exceeded, the side effects of systemic corticosteroids may appear.
  • Elderly patients.
  • Patients with a history of tuberculosis.
  • Patients with severe myocardial or coronary lesions, or severe hypertension.
  • Patients with hyperthyroidism.
  • Patients with liver or kidney disease.
  • Patients with diabetes mellitus.
  • Patients with gastric ulcers.
  • Patients with osteoporosis.
  • Patients with epilepsy.
  • Patients with myasthenia gravis (a chronic autoimmune neuromuscular disease characterized by variable degrees of weakness of the skeletal muscles).
  • Patients with glaucoma (an eye disease in which the optic nerve is damaged).
  • If you experience blurred vision or other visual disturbances.
  • If you have pheochromocytoma (a tumor of the adrenal gland).

This medication contains betamethasone, which may produce a positive result in doping tests.

Using Bronsal Injectable Solution with Other Medications

Tell your doctor or pharmacist if you are using, have recently used, or may need to use any other medication, including those purchased without a prescription.

The following medications may interact with Bronsal. Inform your doctor if you are taking any of them:

  • Xanthine-type medications (e.g., theophylline), as they may enhance the effect of Bronsal.
  • Probenecid (a medication used to treat gout).
  • Medications that induce liver enzymes (barbiturates, phenytoin, and rifampicin).
  • Enzyme inhibitors (CYP3A4) such as ketoconazole and itraconazole (used for fungal infections) may increase the effect of corticosteroids. Therefore, your doctor will closely monitor you if you are taking these medications (including some for HIV: ritonavir, cobicistat).
  • Aspirin (salicylates). Caution should be exercised if Bronsal is used concomitantly with salicylates in patients with hypoprothrombinemia (deficiency of a substance necessary for blood coagulation).
  • Diuretics that increase potassium elimination.
  • Isoproterenol (a medication used to treat asthma).

Pregnancy and Breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medication.

The use of this medication is not recommended during pregnancy and breastfeeding, except on explicit medical indication.

Newborns of mothers who received betamethasone near the end of pregnancy may have low blood sugar levels after birth.

Driving and Using Machines

Not described.

This medication contains sodium, methylparaben, propylparaben, and sodium metabisulfite.

It may cause allergic reactions (possibly delayed) and, exceptionally, bronchospasm (sudden feeling of suffocation) because it contains methylparaben and propylparaben.

It may cause severe allergic reactions or bronchospasm (sudden feeling of suffocation) because it contains sodium metabisulfite.

This medication contains less than 23 mg (1 mmol) of sodium per dose, so it is considered essentially "sodium-free".

3. How to Use Bronsal Injectable Solution

Follow your doctor's instructions for administering Bronsal exactly. Consult your doctor or pharmacist if you have any questions.

The recommended dose in adults is one injection every 12-24 hours via intramuscular route.

If you use more Bronsal Injectable Solution than you should

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone 91 562 04 20, indicating the medication and the amount ingested.

If you forget to use Bronsal Injectable Solution

Do not use a double dose to make up for forgotten doses.

If you have any other questions about using this medication, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible Side Effects

Like all medications, Bronsal can cause side effects, although not everyone will experience them.

The severity of side effects associated with prolonged treatment increases with the dose and duration of treatment. Short-term treatments usually do not produce adverse reactions.

Frequent (may affect 1 to 10 in every 100 patients): gastrointestinal disorders (nausea, vomiting, abdominal pain, diarrhea), headache, excitement, insomnia or drowsiness, osteoporosis, bone fragility, hyperglycemia, polyphagia (abnormal increase in the need to eat), delayed wound healing, propensity to infections (oropharyngeal candidiasis), signs of adrenal hyperactivity (Cushing's syndrome), hirsutism (excessive hair growth in women, on the face and body), skin hyperpigmentation, gastric ulcers.

Uncommon (may affect 1 to 10 in every 1,000 patients): edema (swelling), hypertension, heart failure, hypokalemia (decreased potassium levels), amenorrhea (temporary or permanent absence of menstrual flow), sweating, neurological disorders, intracranial hypertension, acute pancreatitis, thromboembolism, myasthenia (a chronic autoimmune neuromuscular disease characterized by variable degrees of weakness of the skeletal muscles).

Frequency unknown: hypoaesthesia, blurred vision (see also section 4.4).

If you experience side effects, consult your doctor or pharmacist, even if they are not listed in this package leaflet.

5. Storage of Bronsal Injectable Solution

No special storage conditions are required.

Keep this medication out of sight and reach of children.

Do not use this medication after the expiration date stated on the packaging after CAD. The expiration date is the last day of the month indicated.

Medications should not be disposed of through wastewater or household waste. Deposit the packaging and any unused medication in the pharmacy's SIGRE point. If in doubt, ask your pharmacist how to dispose of the packaging and any unused medication. This will help protect the environment.

6. Package Contents and Additional Information

Composition of Bronsal Injectable Solution

The active ingredients are (per 4 ml ampoule): betamethasone 2 mg (betamethasone phosphate and sodium), diprophylline 250 mg, and guaifenesin 200 mg.

The other ingredients are: sodium metabisulfite (E-223), disodium edetate, anhydrous disodium hydrogen phosphate, methylparaben (E-218), propylparaben (E-216), and water for injectable preparations.

Appearance of the Product and Package Contents

Bronsal is a clear and colorless solution. Each package contains 5 ampoules of 4 ml.

Marketing Authorization Holder and Manufacturer

Holder

IONFARMA, S.L.U.

Perú, 228

08020 Barcelona, Spain.

Manufacturer

LABORATORIOS REIG JOFRÉ, S.A.

Gran Capitán, 10

08970 Sant Joan Despí, Barcelona, Spain.

Date of the Last Revision of this Package Leaflet:April 2022.

Detailed and updated information on this medication is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for BRONSAL Injectable Solution

Discuss questions about BRONSAL Injectable Solution, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Chikeluo Okeke

General medicine 4 years exp.

Dr Chikeluo Okeke is an internal medicine doctor with extensive international clinical experience. Originally from Nigeria, he has worked across multiple European healthcare systems and currently practises in Sweden. This professional path has given him a strong understanding of different medical approaches and the ability to work effectively with patients from diverse cultural and linguistic backgrounds.

Dr Okeke focuses on general internal medicine and adult primary care, combining clinical accuracy with careful attention to lifestyle, personal context, and everyday health concerns. His consultations are particularly well suited for people who seek medical advice online, live abroad, or need clear guidance without unnecessary complexity.

He provides online consultations covering symptom assessment, prevention, and long-term management of chronic conditions, helping patients understand what is happening and decide on appropriate next steps.

Common reasons for consultation:

  • General internal medicine concerns and initial health assessment.
  • Acute symptoms such as fever, cough, infections, pain, or weakness.
  • Chronic conditions and treatment adjustment.
  • Blood pressure issues, fatigue, metabolic concerns.
  • Preventive consultations and routine check-ups.
  • Interpretation of laboratory results and medical reports.
  • Medical advice for patients receiving care online.

Dr Okeke is known for his clear communication, calm approach, and cultural awareness. He listens carefully, explains medical decisions in a structured way, and supports patients in making informed choices about their health.

Online consultations with Dr Chikeluo Okeke offer reliable internal medicine care without geographic limitations, focused on medical relevance, clarity, and patient comfort.

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€60
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Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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Doctor

Daniel Cichi

Family medicine 24 years exp.

Dr Daniel Cichi is a family medicine doctor with over 20 years of clinical experience. He provides online consultations for adults, supporting patients with acute symptoms, chronic conditions, and everyday health concerns that require timely medical guidance. His background includes work in emergency care, ambulance services, and family medicine, which allows him to assess symptoms quickly, identify warning signs, and help patients choose the safest next steps – whether that means home care, treatment adjustment, or in-person evaluation. Patients commonly consult Dr Daniel Cichi for: 

  • acute symptoms: fever, infections, flu-like illness, cough, sore throat, shortness of breath;
  • chest discomfort, palpitations, dizziness, fatigue, and blood pressure concerns;
  • digestive problems: abdominal pain, nausea, diarrhoea, constipation, reflux;
  • sexually transmitted infections, erectile dysfunction;
  • muscle, joint, and back pain, minor injuries, post-traumatic symptoms;
  • chronic conditions: hypertension, diabetes, high cholesterol, thyroid disorders, weight loss, hair loss;
  • review and interpretation of lab tests, imaging reports, and medical documents;
  • medication review and treatment adjustment;
  • medical advice while travelling or living abroad;
  • second opinions and guidance on whether in-person care is needed.

Dr Cichi’s consultations are structured and practical. He focuses on clear explanations, risk assessment, and actionable recommendations, helping patients understand their symptoms and make informed decisions about their health.

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€55
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Doctor

Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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€60

Frequently Asked Questions

Is a prescription required for BRONSAL Injectable Solution?
BRONSAL Injectable Solution requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in BRONSAL Injectable Solution?
The active ingredient in BRONSAL Injectable Solution is diprophylline, combinations. This information helps identify medicines with the same composition but different brand names.
Who manufactures BRONSAL Injectable Solution?
BRONSAL Injectable Solution is manufactured by Ionfarma S.L.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of BRONSAL Injectable Solution online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether BRONSAL Injectable Solution is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to BRONSAL Injectable Solution?
Other medicines with the same active substance (diprophylline, combinations) include ELIXIFILIN 5.33 mg/ml ORAL SOLUTION, FLUIDASA 150 mg HARD CAPSULES, FLUIDASA 20 mg/ml ORAL DROPS IN SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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