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SPIRAXIN 200 mg Film-Coated Tablets

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Doctor
5.0(11)

Anna Biriukova

Gastroenterology6 years of experience

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
Book a video appointment
€66
This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use SPIRAXIN 200 mg FILM-COATED TABLETS

Contents of the leaflet

  1. Introduction
  2. What Spiraxin is and what it is used for
  3. What you need to know before you take Spiraxin
  4. How to take Spiraxin
  5. Possible side effects
  6. Storage of Spiraxin
  7. Contents of the pack and other information
  8. Composition of Spiraxin

Introduction

Package Leaflet: Information for the Patient

SPIRAXIN 200 mg film-coated tablets

Rifaximin

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack:

  1. What Spiraxin is and what it is used for
  2. What you need to know before you take Spiraxin
  3. How to take Spiraxin
  4. Possible side effects
  5. Storage of Spiraxin
  6. Contents of the pack and other information

1. What Spiraxin is and what it is used for

Spiraxin belongs to a group of medicines called intestinal anti-infectives, antibiotics.

Informative text about the correct use of antibiotics and their proper elimination after treatment

Spiraxin is indicated in:

  • Bacterial enterocolitis resistant to symptomatic treatment in patients at risk due to associated pathology, immunodepression, or advanced age.
  • Pseudomembranous colitis in patients resistant to vancomycin.
  • Acute diverticulitis.
  • Pre- and post-operative prophylaxis in gastrointestinal tract surgery.
  • Adjuvant therapy in hyperammonemia (excessive increase in blood ammonia concentration).
Doctor consultation

Not sure if this medicine is right for you?

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2. What you need to know before you take Spiraxin

Do not take Spiraxin:

  • If you are allergic to the active substance, rifamycin derivatives, or any of the other components of this medicine (listed in section 6).
  • If you have intestinal obstruction.
  • If you have severe intestinal ulcerative lesions.
  • If you have complicated diarrhea with fever or blood in the stool.

Warnings and precautions

  • Consult your doctor or pharmacist before starting to take Spiraxin.
  • If you have ever developed a severe skin rash or skin peeling, blisters, and/or sores in the mouth after taking rifaximin.
  • During prolonged treatments at high doses, or in cases of intestinal injury, a slight absorption of the product may occur, and when eliminated, it may cause a reddish coloration of the urine, which is of no significant relevance.
  • Rifaximin should be withdrawn if symptoms of diarrhea persist or worsen after 48 hours.
  • As with the use of most antibiotics, during treatment with rifaximin, cases of diarrhea associated with Clostridioidesdifficile(CDAD) have been reported; therefore, the potential association of rifaximin treatment with CDAD or pseudomembranous colitis cannot be ruled out.

Be particularly careful with rifaximin:

Severe skin reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis, have been reported in association with rifaximin treatment. Most cases were reported in patients with liver disease (such as cirrhosis or hepatitis). Stop using rifaximin and seek immediate medical attention if you notice any of the symptoms related to these severe skin reactions described in section 4.

Children

The safety and efficacy of rifaximin have not been established in children under 12 years of age.

Taking Spiraxin with other medicines

  • Tell your doctor or pharmacist if you are using, have recently used, or might use any other medicines.
  • In case of activated charcoal administration, Spiraxin should be taken at least 2 hours after that administration.
  • In case of liver failure, caution should be exercised when taking:
    • Warfarin (a medicine to prevent blood clotting)
    • Antiepileptics (medicines to treat epilepsy)
    • Antiarrhythmics (medicines to treat abnormal heart rhythm)
    • Cyclosporin (an immunosuppressant)
    • Oral contraceptives

Taking Spiraxin with food

Spiraxin can be administered with or without food.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

It is not known whether rifaximin can harm the fetus. Therefore, Spiraxin should not be used during pregnancy.

It is recommended to take additional contraceptive precautions if you are taking Spiraxin with oral contraceptives (see "Taking Spiraxin with other medicines"),

It is not known whether rifaximin is excreted in breast milk. Therefore, Spiraxin should not be used during breastfeeding.

Driving and using machines

Spiraxin has a negligible influence on the ability to drive and use machines, although some cases of dizziness or drowsiness have been reported.

Spiraxin contains sodium

This medicine contains less than 23 mg of sodium (1 mmol) per tablet; this is essentially "sodium-free".

3. How to take Spiraxin

Follow exactly the administration instructions of this medicine indicated by your doctor or pharmacist. In case of doubt, consult your doctor or pharmacist again.

Spiraxin is administered orally with a glass of water.

The recommended dose is 200 mg (1 tablet) every 6 hours, until symptoms subside. This dose may be increased to 400 mg in adults every 8 hours, in those cases that, due to their complexity, may require a dose increase and always under medical criteria. It is recommended not to exceed 7 days of treatment.

No dose adjustment is necessary in patients with liver or kidney failure. Although no dose changes are expected, caution should be exercised in patients with impaired renal function.

Use in children

The safety and efficacy of rifaximin have not been established in children under 12 years of age. No dosage recommendation can be made.

If you take more Spiraxin than you should

If you have taken more Spiraxin than you should, consult your doctor or pharmacist immediately, or call the Toxicology Information Service, phone 91-562 04 20, indicating the medicine and the amount taken.

If you forget to take Spiraxin

Do not take a double dose to make up for forgotten doses.

If you stop taking Spiraxin

If you have any other questions about the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Stop using rifaximin and seek immediate medical attention if you notice any of the following symptoms:

  • Reddish patches, not raised, in a target or circular shape on the trunk, often with central blisters, skin peeling, mouth ulcers, and/or sores in the mouth, throat, nose, genitals, and eyes.

These severe skin rashes can be preceded by fever and flu-like symptoms.

Similarly, many of the side effects, mainly related to the gastrointestinal tract, may be caused by the same disease that motivated the treatment.

Common side effects (at least 1 in 100 patients):

  • Dizziness, headache
  • Constipation, abdominal pain, abdominal distension, diarrhea, flatulence, feeling of needing to defecate, involuntary and painful or ineffective straining, nausea, vomiting
  • Fever

Uncommon side effects (at least 1 in 1,000 patients):

  • Increased blood pressure
  • Palpitations
  • Abnormal white blood cell count in the blood (increased lymphocytes and monocytes and decreased neutrophils)
  • Decreased sensitivity, migraine, forehead or one-sided headache, tingling sensation, drowsiness
  • Double vision
  • Ear pain, sensation of the room spinning (vertigo)
  • Difficulty breathing, nasal congestion, dry throat, sore throat, cough, runny nose
  • Fluid accumulation in the abdomen (ascites), heavy digestion, gastrointestinal motility disorders, upper abdominal pain, blood in the stool, mucous stools, hard stools, dry lips, taste disorders
  • Abnormal urine test results: glucose in the urine, increased urine output, increased frequency of urination, protein in the urine, blood in the urine
  • Skin rashes and eruptions that can be sudden, sunburn
  • Back pain, muscle weakness, generalized muscle pain, muscle cramps, neck pain
  • Loss of appetite, dehydration
  • Candidiasis (a type of fungal infection), inflammation or infection of the nose and/or throat, upper respiratory tract infection, cold sores
  • Hot flashes
  • Exhaustion, chills, cold sweat, pain and discomfort, swollen arm (peripheral edema), excessive sweating, flu-like symptoms
  • Abnormal liver test results (increased aspartate aminotransferase)
  • Prolonged and irregular menstrual periods
  • Insomnia, abnormal dreams, depressed mood, nervousness

Rare side effects (frequency not known):

  • Abnormal blood coagulation test results (International Normalized Ratio)
  • Decreased platelet count in the blood
  • Severe allergic reactions, hypersensitivity
  • Fainting sensation
  • Swelling of skin and mucous membranes, dermatitis, skin peeling dermatitis, eczema, erythemas, itching, red spots on the skin (purpura), hives
  • Clostridium difficileinfection
  • Liver function test abnormalities

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Medicines Surveillance System for human use, https://www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Spiraxin

No special storage conditions are required.

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiry date is the last day of the month indicated.

Medicines should not be disposed of via wastewater or household waste. Place the carton and any remaining medicine in the pharmacy's SIGRE collection point. If you have any doubts, ask your pharmacist how to dispose of the carton and any remaining medicine. This will help protect the environment.

6. Contents of the pack and other information

Composition of Spiraxin

  • The active substance is rifaximin. Each tablet contains 200 mg of rifaximin.
  • The other components (excipients) are sodium carboxymethyl starch (type A) (potato), glycerol distearate, anhydrous colloidal silica (E-551), talc (E-553b), microcrystalline cellulose (E-460), hypromellose (E-464), titanium dioxide (E-171), disodium edetate, propylene glycol (E-1520), and red iron oxide (E-172).

Appearance of the product and pack contents

Spiraxin is a film-coated tablet, biconvex, round, and pink in color. It is available in packs of 12 and 28 tablets.

Marketing authorization holder and manufacturer

Marketing authorization holder:

Alfasigma S.p.A

Via Ragazzi Del ’99, n.5

40133 Bologna. ITALY

Manufacturer:

Alfasigma, S.p.A.

Via Enrico Fermi, 1

65020 Alanno, Pescara. ITALY

or

Alfasigma S.p.A

Via Pontina km 30.400

00071 – Pomezia, Roma. ITALY

Local representative:

Alfasigma España, S.L.

C/ Aribau 195, 4º

08021 Barcelona. España

Date of the last revision of this leaflet:April 2024

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for SPIRAXIN 200 mg FILM-COATED TABLETS

Discuss questions about SPIRAXIN 200 mg FILM-COATED TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(11)

Anna Biriukova

Gastroenterology6 years of experience

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
Book a video appointment
€66
Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
Doctor
5.0(12)

Yevgen Yakovenko

General medicine12 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment
€72
Doctor
5.0(3)

Lina Travkina

General medicine13 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.

  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.

  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.

  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.

  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.

  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.

  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.

  • Medical advice and follow-up consultations.

  • Test interpretation and diagnostic guidance.

  • Structured support for undiagnosed complaints.

  • Second opinion on diagnoses and treatment plans.

  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.

  • Post-operative recovery support and pain management.

  • Preconception counselling and postpartum support.

  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Book a video appointment
€75
Doctor
5.0(21)

Nuno Tavares Lopes

General medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies

  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management

  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses

  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment

  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance

  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis

  • Pain management: acute and chronic pain, post-surgical care

  • Public health: prevention, health screenings, long-term monitoring

  • Sick leave (Baixa médica) connected to Segurança Social in Portugal

  • IMT medical certificates for driving licence exchange

Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Book a video appointment
€70

Get SPIRAXIN 200 mg FILM-COATED TABLETS Prescription Online

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Electronic prescription sent to your email — valid across Spain.

Frequently Asked Questions

SPIRAXIN 200 mg FILM-COATED TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

The active ingredient in SPIRAXIN 200 mg FILM-COATED TABLETS is rifaximin. This information helps identify medicines with the same composition but different brand names.

The average pharmacy price for SPIRAXIN 200 mg FILM-COATED TABLETS is around 9.21 EUR. Prices may vary depending on the manufacturer and dosage form.

SPIRAXIN 200 mg FILM-COATED TABLETS is manufactured by Alfasigma S.P.A.. Pharmacy brands and packaging may differ depending on the distributor.

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether SPIRAXIN 200 mg FILM-COATED TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy SPIRAXIN 200 mg FILM-COATED TABLETS in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

Other medicines with the same active substance (rifaximin) include TIXTAR 550 MG FILM-COATED TABLETS, TIXTELLER 550 MG FILM-COATED TABLETS, DIFICLIR 200 mg FILM-COATED TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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