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PANKREOFLAT 172 MG/80 MG FILM-COATED TABLETS

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About the medicine

How to use PANKREOFLAT 172 MG/80 MG FILM-COATED TABLETS

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Pankreoflat 172 mg/80 mg Coated Tablets

Pancreatin / Dimeticone

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

Follow exactly the administration instructions of the medicine contained in this leaflet or as indicated by your doctor or pharmacist.

  • Keep this leaflet, you may need to read it again.
  • If you need advice or more information, ask your pharmacist.
  • If you experience side effects, consult your doctor or pharmacist, even if it is a side effect not listed in this leaflet. See section 4.
  • You should consult a doctor if your symptoms worsen or do not improve after 10 days.

Contents of the Package Leaflet

  1. What is Pankreoflat and what is it used for
  2. What you need to know before taking Pankreoflat
  3. How to take Pankreoflat
  4. Possible side effects
  5. Storage of Pankreoflat
  6. Contents of the pack and further information
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1. What is Pankreoflat and what is it used for

Pankreoflat belongs to a group of medicines known as pancreatic enzymes and their combinations.

Thanks to its activity on fats, carbohydrates, and proteins, pancreatic enzymes facilitate digestion and promote the absorption of food in those individuals whose body is not able to produce these enzymes in sufficient quantity. Additionally, dimeticone acts on excess gases accumulated in the digestive tract, facilitating their elimination and relieving the discomfort they cause.

Pankreoflat is indicated for the relief of symptoms of digestive disorders in which aerophagia (swallowing of air), flatulence (accumulation of gases in the digestive system), such as stomach heaviness and slow digestion related to pancreatic enzyme insufficiency in adults and adolescents over 12 years old.

2. What you need to know before taking Pankreoflat

Do not take Pankreoflat

  • If you are allergic (hypersensitive) to pancreatin (lipase, amylase, protease) of porcine origin, dimeticone, cow's milk protein, or any of the other components of this medicine (listed in section 6).
  • If you have acute pancreatitis (acute inflammation of the pancreas).

Warnings and precautions

Consult your doctor or pharmacist before starting to take Pankreoflat.

Be particularly careful with Pankreoflat:

  • If your symptoms worsen or persist after 10 days, you should stop treatment and consult a doctor.
  • If allergy symptoms (hypersensitivity) appear, treatment should be stopped and your doctor informed.
  • If you have lactose intolerance or a milk protein allergy, do not use this medicine.
  • If you have or have a history of hyperuricemia (elevated uric acid in the blood), gout, or kidney failure, you should use Pankreoflat with caution.

In any case, immediately inform your doctor so that he can decide whether to continue or not with the treatment or adjust it to your specific case, for example, by changing the recommended dose.

Children

Pankreoflat is not recommended for the treatment of infant colic due to the lack of information in this patient population.

Taking Pankreoflat with other medicines

Inform your doctor or pharmacist if you are using, have recently used, or may need to use any other medicine, as it may be necessary to interrupt treatment or adjust the dose of one of them.

Antacids such as calcium carbonate or magnesium hydroxide may decrease the therapeutic effects of Pankreoflat.

If you are taking iron supplements, you should space their administration at least 2 hours apart from Pankreoflat.

Taking Pankreoflat with food, drinks, and alcohol

It is not recommended to consume alcoholic beverages while being treated with Pankreoflat, as they may decrease the activity of the medicine.

Intake of foods that increase gas formation and carbonated beverages should be avoided.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

The possible benefit/risk should be assessed in case of prescribing and/or dispensing this medicine to a woman during pregnancy or breastfeeding, consulting with your doctor and/or pharmacist.

Driving and using machines

Given the characteristics of this medicine, it is unlikely that its administration will affect the ability to drive and operate hazardous machinery.

Important information about some of the components of Pankreoflat

This medicine contains sucrose. If your doctor has told you that you have an intolerance to certain sugars, consult with them before taking this medicine.

This medicine contains lactose. If your doctor has told you that you have an intolerance to certain sugars, consult with them before taking this medicine.

This medicine may cause allergic reactions in patients with a cow's milk protein allergy.

This medicine may produce allergic reactions (possibly delayed) because it contains methyl parahydroxybenzoate (E-218) and propyl parahydroxybenzoate (E-216).

This medicine contains less than 23 mg of sodium (1 mmol) per tablet; that is, it is essentially "sodium-free".

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3. How to take Pankreoflat

Follow exactly the administration instructions of Pankreoflat contained in this leaflet or as indicated by your doctor or pharmacist.

In case of doubt, ask your doctor or pharmacist.

Adults and adolescents over 12 years old: the recommended dose is 1 to 2 coated tablets at each main meal. The dose should be adjusted individually according to symptoms and the fat content of the diet.

The tablets should be taken whole, without chewing or breaking, with sufficient liquid (water), during or after main meals.

Use in children

It should not be administered to children under 12 years old without medical supervision. Pankreoflat is not recommended in cases of infant colic.

If you take more Pankreoflat than you should

If you have taken more Pankreoflat than you should, consult your doctor immediately, go to the nearest hospital, or call the Toxicology Information Service. Phone: 91. 562.04.20, indicating the medicine and the amount ingested.

If you forget to take Pankreoflat:

In case you forget to take a dose, wait until the next meal and take the usual number of tablets. Do not take a double dose to make up for forgotten doses.

If you have any other doubts about the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects

The side effects observed are described below according to their frequency of occurrence:

Very common (occur in at least 1 in 10 patients), common (occur in between 1 and 10 in 100 patients), uncommon (occur in between 1 and 10 in 1,000 patients), rare (occur in between 1 and 10 in 10,000 patients), very rare (occur in less than 1 in 10,000 patients).

Like all medicines, this medicine can cause side effects, although not everyone gets them.

The side effects reported are usually mild.

The possible side effects described below are classified according to their frequency of occurrence:

Very common side effects(occur in at least 1 in 10 patients)

  • Abdominal pain, nausea, vomiting, diarrhea.

Uncommon side effects(occur in between 1 and 10 in 1,000 patients)

  • Constipation.

Very rare side effects(occur in less than 1 in 10,000 patients):

  • Weight loss.
  • Hyperuricemia (elevated uric acid levels in the blood), hyperuricosuria (elevated uric acid levels in urine).
  • Abdominal distension (feeling of bloating in the abdomen), colon stenosis (narrowing of the colon), intestinal obstruction, perianal irritation, dyspepsia (feeling of heavy digestion, abdominal bloating, early satiety),
  • Pruritus (itching sensation on the skin), skin rash, urticaria.
  • Edema, pain.

Side effects with unknown frequency:

  • Hypersensitivity reactions 1
  • Anaphylactic reactions (a type of allergic reaction that can manifest with the appearance of a skin rash, itching, and/or localized edema)
  • Angioedema (allergic reaction characterized by the appearance of skin and mucous membrane swelling)
  • Anaphylactic shock (severe allergic reaction that can manifest with difficulty breathing, or decreased blood pressure)
  • Mouth ulcers.
  1. The following hypersensitivity symptoms have been observed (urticaria, angioedema, anaphylactic shock, asthma in patients with a history of intolerance or allergy to milk proteins).

Reporting of side effects

If you experience any type of side effect, consult your doctor or pharmacist, even if it is a possible side effect not listed in this leaflet. You can also report them directly through the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es.

By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Pankreoflat

Store below 30°C.

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiration date stated on the packaging, after EXP. The expiration date is the last day of the month indicated.

Medicines should not be disposed of via wastewater or household waste. Deposit the packaging and medicines you no longer need at the SIGRE collection point in your pharmacy. In case of doubt, ask your pharmacist how to dispose of the packaging and medicines you no longer need. This way, you will help protect the environment.

6. Contents of the pack and further information

Composition of Pankreoflat

  • The active ingredients are pancreatin and dimeticone. Each coated tablet contains 80 mg of dimeticone and pancreatin in an amount equivalent to 6,000 Ph. Eur. units of amylase, 6,000 Ph. Eur. units of lipase, and 400 Ph. Eur. units of protease.
  • The other components are: skimmed milk powder containing lactose in its composition, hydroxypropyl methylcellulose (E464), gum arabic (E414), methyl parahydroxybenzoate (E218), propyl parahydroxybenzoate (E216), sorbic acid (E200), sucrose, hydroxypropyl cellulose (E463), magnesium stearate, polyvinylpyrrolidone/polyvinyl acetate copolymer, shellac (E904), acetylated monoglycerides, silicon dioxide (E551), talc (E553b), povidone (E1201), polyethylene glycol (E1521), sodium carmellose (E466), titanium dioxide (E171), and carnauba wax.

Appearance of the product and pack contents

Pankreoflat are white, oblong, coated tablets.

Pack sizes of 20 and 50 coated tablets.

Not all pack sizes may be marketed.

Marketing authorization holder

Faes Farma, S.A.

Autonomia Etorbidea, 10

48940 Leioa (Bizkaia)

Spain

Manufacturer

Faes Farma, S.A.

Maximo Agirre Kalea, 14

48940 Leioa (Bizkaia)

Spain

Date of the last revision of this leaflet: July 2019

Detailed information about this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for PANKREOFLAT 172 MG/80 MG FILM-COATED TABLETS

Discuss questions about PANKREOFLAT 172 MG/80 MG FILM-COATED TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
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Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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Bulat Garipov

General medicine 15 years exp.

Dr. Bulat Garipov is a radiologist with more than 15 years of experience, specializing in magnetic resonance imaging (MRI). Throughout his professional career, he has worked in leading diagnostic imaging centers, both in on-site practice and teleradiology, which has allowed him to develop a broad and versatile approach to radiology.

Over the years, he has gained solid experience in interpreting MRI studies in various areas, including:

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Additionally, Dr. Garipov is open to new collaboration opportunities in radiology and teleradiology projects. He offers his expertise in MRI, providing both first and second readings of studies, as well as advanced image interpretation, ensuring accurate and high-quality diagnostics.

You could consult Dr. Bulat Garipov in cases where accurate interpretation of MRI studies or a second expert opinion is required. His expertise is especially valuable in cases of suspected neurological conditions, back and joint pain, vascular disorders, as well as in the diagnosis of abdominal and pelvic diseases. The doctor also provides support in complex or unclear clinical situations, including the review of previously performed studies, which helps improve diagnostic accuracy and determine the optimal treatment strategy. A teleradiology format is available, allowing you to receive a professional opinion remotely.

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Alexander Nazarchuk

Allergology 7 years exp.

Dr. Alexander Nazarchuk is a physician specialising in allergology and internal medicine. He provides online consultations for adults, following the principles of evidence-based medicine — no outdated treatments or unnecessary tests, with clear explanations and a personalised approach. He helps patients with a wide range of allergic and therapeutic conditions, from common day-to-day complaints to complex cases involving allergies, gastrointestinal issues, cardiovascular concerns, respiratory symptoms, and more.

You can consult Dr. Nazarchuk for:

  • Test interpretation and guidance on diagnostic plans.
  • Allergic rhinitis, hay fever, bronchial asthma (including severe cases).
  • Food and drug allergies, skin rashes, angioedema.
  • Atopic dermatitis, urticaria, contact allergies.
  • Allergen-specific immunotherapy (AIT) – initiation and ongoing management.
  • Abdominal pain, bloating, changes in bowel habits, nausea, heartburn.
  • High blood pressure and adjustment of baseline antihypertensive therapy.
  • Hyperlipidaemia and elevated cholesterol.
  • Cough, nasal congestion, fever, sore throat.
  • Anaemia, including iron deficiency and related conditions.
  • Other issues related to allergology and internal medicine.

During consultations, Dr. Nazarchuk takes a thorough, structured approach — analysing symptoms, identifying potential causes, and helping patients make informed decisions. Whether treatment, further investigation, or monitoring is needed, he explains each step clearly so you understand your health and how best to manage it.

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Andrei Popov

General medicine 7 years exp.

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

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Sviatoslav Chekhun

Oncology 13 years exp.

Dr. Sviatoslav Chekhun is a medical oncologist with international clinical and research experience, specializing in modern medical oncology and a personalized approach to cancer treatment.

Currently (since 2025), he works as a Medical Oncologist at Institut Català d’Oncologia (Girona, Spain). Previously, he completed his residency in Medical Oncology and was involved in clinical research at Hospital Universitari Germans Trias i Pujol.

Dr. Chekhun has a strong academic and scientific background. He served as a lecturer in Internal Medicine at O.O. Bohomolets National Medical University and conducted research in experimental oncology at the R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology.

Earlier in his career, he worked as a medical oncologist at the Kyiv City Clinical Oncological Center and contributed to regulatory evaluation of medicinal products at the State Expert Center of the Ministry of Health of Ukraine.

When to consult Dr. Chekhun:

  •  for diagnosis or clarification of a cancer diagnosis
  •  to obtain a second opinion on an existing treatment plan 
  •  when you need a personalized treatment strategy 
  •  for interpretation of test results, CT, MRI, PET-CT, and biopsies 
  •  when choosing between treatment options (chemotherapy, targeted therapy, immunotherapy) 
  •  in case of doubts about treatment strategy or disease progression 

Consultation format

Dr. Chekhun provides online consultations, where you can receive:

  •  expert second opinion 
  •  detailed case review 
  •  recommendations based on current international treatment guidelines 
  •  personalized treatment and follow-up plan 

Important:
Prescription and monitoring of medications must be carried out by your treating physician in an in-person (offline) setting. An online consultation does not replace a face-to-face visit but helps you make more informed decisions about your treatment.

Dr. Sviatoslav Chekhun combines clinical practice, research, and international experience, enabling him to provide patients with modern, evidence-based approaches in oncology.

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Frequently Asked Questions

Is a prescription required for PANKREOFLAT 172 MG/80 MG FILM-COATED TABLETS?
PANKREOFLAT 172 MG/80 MG FILM-COATED TABLETS does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in PANKREOFLAT 172 MG/80 MG FILM-COATED TABLETS?
The active ingredient in PANKREOFLAT 172 MG/80 MG FILM-COATED TABLETS is Enzyme preparations. This information helps identify medicines with the same composition but different brand names.
Who manufactures PANKREOFLAT 172 MG/80 MG FILM-COATED TABLETS?
PANKREOFLAT 172 MG/80 MG FILM-COATED TABLETS is manufactured by Faes Farma S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of PANKREOFLAT 172 MG/80 MG FILM-COATED TABLETS online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether PANKREOFLAT 172 MG/80 MG FILM-COATED TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to PANKREOFLAT 172 MG/80 MG FILM-COATED TABLETS?
Other medicines with the same active substance (Enzyme preparations) include KREON 10,000 U HARD GASTRORESISTANT CAPSULES, KREON 25,000 U HARD GASTRO-RESISTANT CAPSULES, KREON 35,000 U HARD GASTRORESISTANT CAPSULES. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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