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MELATONIN PERRIGO 3 mg TABLETS

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About the medicine

How to use MELATONIN PERRIGO 3 mg TABLETS

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Melatonin Perrigo 3 mg Tablets

Read this package leaflet carefully before you start taking this medicine, because it contains important information for you.

Follow exactly the administration instructions of this medicine contained in this package leaflet or as indicated by your doctor or pharmacist.

  • Keep this package leaflet, you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience side effects, consult your doctor or pharmacist, even if it is a side effect not listed in this package leaflet. See section 4.
  • You should consult a doctor if it worsens or does not improve after 6 days.

Contents of the Package Leaflet:

  1. What is Melatonin Perrigo and what is it used for
  2. What you need to know before taking Melatonin Perrigo
  3. How to take Melatonin Perrigo
  4. Possible side effects
  5. Storage of Melatonin Perrigo
  6. Contents of the pack and further information

1. What is Melatonin Perrigo and what is it used for

The active substance of Melatonin Perrigo is melatonin. Melatonin is a hormone that is also produced naturally by the body.

Melatonin is used for the treatment of jet-lag in adults. Jet-lag is a disruption of the sleep-wake rhythm that can occur after crossing several time zones during air travel.

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2. What you need to know before taking Melatonin Perrigo

Do not take Melatonin Perrigo

  • if you are allergic to melatonin or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions

Consult your doctor or pharmacist before taking this medicine in the following cases:

  • If you are so drowsy that it could pose a risk to your safety.
  • If you have a liver disease. There are no data available on the effect of Melatonin Perrigo in people with liver diseases, so the use of this medicine is not recommended in these cases.
  • If you have epilepsy, the use of melatonin may increase the number of epileptic seizures.
  • If you have an autoimmune disease. In patients with an autoimmune disease, rare cases of worsening symptoms have been reported after taking melatonin. Therefore, talk to your doctor if you want to take this medicine. The use of this medicine is not recommended in people with autoimmune diseases.
  • If your blood sugar level is too high or if you have diabetes. If you take melatonin during a meal rich in carbohydrates (e.g., bread, potatoes, pasta, sugar), this may alter blood sugar levels. Therefore, you should not use this product in the 2-hour period before to 3 hours after a meal. Always take this product at least 3 hours after a meal if you suffer from severely altered glucose tolerance or diabetes.
  • If you are a smoker. The effect of this medicine may not be as strong in people who smoke, as the components of tobacco smoke can accelerate the breakdown of melatonin in the liver.

Children and adolescents up to 18 years

Do not give this medicine to children. The use of this product has not been studied in children, and therefore, its safety and efficacy are not known.

Other medicines and Melatonin Perrigo

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicine at the same time as Melatonin Perrigo.

This is particularly important if you are taking sleeping pills, sedatives (such as zolpidem, imipramine, and thioridazine), antidepressants (such as fluvoxamine), estrogens (contraceptives or hormone replacement therapy), anticoagulants, medicines to prevent epileptic seizures, anti-inflammatory drugs, and medicines for skin problems.

Taking Melatonin Perrigo with food and drinks

Do not drink alcohol before, during, or after taking melatonin.

Food can increase the concentration of melatonin in the blood. The use of melatonin in combination with carbohydrate-rich meals (e.g., bread, potatoes, pasta, sugar) may affect blood sugar regulation for several hours. You should not eat in the 2-hour period before to 2 hours after taking melatonin. If your blood sugar levels are too high or you have diabetes, then you should not eat in the 2-hour period before to 3 hours after taking melatonin.

Pregnancy and breastfeeding

You should avoid using this medicine if you are pregnant, think you may be pregnant, want to become pregnant, or are breastfeeding.

Driving and using machines

Melatonin can cause drowsiness. You should not drive or use machines if you feel drowsy. Consult your doctor if symptoms of drowsiness persist.

Melatonin Perrigo contains lactose

Each Melatonin Perrigo 3 mg tablet contains 65.3 mg of lactose monohydrate.

Consult your doctor before taking this medicine if you know you cannot tolerate certain sugars.

Melatonin Perrigo contains sodium

This medicine contains less than 1 mmol of sodium (23 mg) per tablet; this is essentially "sodium-free".

3. How to take Melatonin Perrigo

Follow exactly the administration instructions of this medicine contained in this package leaflet or as indicated by your doctor or pharmacist. If in doubt, ask your doctor or pharmacist.

The recommended dose is 3 to 5 mg per day, for a period of 3 to 6 days.

The tablets should be swallowed whole with a little water. The score line is only to facilitate breaking the tablet if you find it difficult to swallow whole.

Take the tablets just before bedtime (local time) from the first day that the sleep rhythm is disrupted. It is recommended not to take the tablets before 8:00 PM or after 4:00 AM at the destination.

Also, see the section "Melatonin Perrigo with food and drinks".

If you take more Melatonin Perrigo than you should

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone 91 562 04 20, indicating the medicine and the amount taken.

Taking a daily dose higher than recommended may cause you to feel more drowsy and suffer from dizziness, headache, and nausea. No special treatment is required after an overdose.

If you forget to take Melatonin Perrigo

If you forget to take the tablet at bedtime and wake up during the night, you can take the missed dose. Do not take a double dose to make up for missed doses.

If you stop taking Melatonin Perrigo

You can stop using this medicine at any time. No harmful effects are known from stopping treatment or ending it prematurely. To date, no cases of withdrawal symptoms have been reported after stopping melatonin treatment.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

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4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

The following side effects have been reported after taking melatonin:

  • Abnormal dreams.
  • Abnormal behavior.
  • Abnormal sensation.
  • Abnormal stools.
  • Asthma.
  • Incontinence.
  • Pallor.
  • Nosebleeds.
  • Vomiting.
  • Abdominal pain.
  • Constipation.
  • Depression.
  • Depressed mood.
  • Disorientation.
  • Diarrhea.
  • Dizziness.
  • Hyperactivity.
  • Dizziness.
  • Epilepsy.
  • Lack of emotion.
  • Irritability.
  • Weight loss.
  • Weight gain.
  • Hallucinations.
  • Palpitations.
  • Cough.
  • Headache.
  • Skin irritation.
  • Rash.
  • Crying.
  • Hyperactivity.
  • Itching.
  • Breathing difficulties.
  • Feeling of cold.
  • Low blood pressure.
  • Slowness.
  • Migraine.
  • Nausea.
  • Difficulty swallowing.
  • Nightmares.
  • Eye disorder.
  • Ear, nose, and throat problems.
  • Belching.
  • Hypersensitivity.
  • Excessive sweating.
  • Excessive drowsiness.
  • Chest pain.
  • Restlessness.
  • Brown-red rounded marks on the skin.
  • Sleepwalking.
  • Insomnia.
  • Poor quality sleep.
  • Increased heart rate.
  • Mood changes.
  • Itchy bumps on the skin.
  • Increased epileptic seizures.
  • Tremor.
  • Changes in liver function values in the blood.
  • Decreased appetite.
  • Decreased visual acuity.
  • Fatigue.
  • Confusion.
  • Stained skin.
  • Feeling of heaviness in the head.

Reporting of side effects

If you experience any side effects, consult your doctor or pharmacist, even if it is a possible side effect not listed in this package leaflet. You can also report them directly through the Spanish Pharmacovigilance System for Human Use Medicines: www.notificaRAM.es.

By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Melatonin Perrigo

Keep this medicine out of the sight and reach of children.

Store below 25°C. Store in the original packaging to protect from light.

Do not use this medicine after the expiry date stated on the packaging after "EXP". The expiry date is the last day of the month indicated.

The expiry date of the packaging once opened is 1 month.

Do not take this product if you see that the tablets are discolored or damaged.

Medicines should not be disposed of via wastewater or household waste. Dispose of the packaging and any unused medicine in the pharmacy's SIGRE collection point. If in doubt, ask your pharmacist how to dispose of the packaging and any unused medicine. This will help protect the environment.

6. Contents of the pack and further information

Composition of Melatonin Perrigo

The active substance is melatonin.

The other ingredients (excipients) are silicified microcrystalline cellulose (anhydrous colloidal silica and microcrystalline cellulose), lactose monohydrate, sodium carboxymethylcellulose type A, talc, and magnesium stearate.

Appearance of the product and contents of the pack

Melatonin Perrigo 3mg tablets are white to off-white, oblong, with the inscription "MELA 3" on one side and a score line on the other side.

Pack sizes:

  • Carton boxes with 10, 15, 30 tablets in blisters.
  • Plastic containers with 30 tablets.

Not all pack sizes may be marketed.

Marketing authorization holder and manufacturer

Marketing authorization holder:

Perrigo España, S.A.

Pza. Xavier Cugat, 2 Edif. D Pl. 1ª.

08174 Sant Cugat del Vallès (Barcelona)

Spain

Manufacturer

Omega Pharma Manufacturing GmbH & Co. KG

Benzstrasse 25

71083 Herrenberg,

Germany

This medicine is authorized in the Member States of the European Economic Area under the following names:

Netherlands

Melatonin Omega Pharma 3 mg tablets

Spain

Melatonina Perrigo 3 mg tablets

Date of the last revision of this package leaflet: July 2022

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for MELATONIN PERRIGO 3 mg TABLETS

Discuss questions about MELATONIN PERRIGO 3 mg TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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Pedro Alvarez Guerrero

Psychiatry 8 years exp.

Dr. Alvarez Guerrero graduated in Medicine from the San Pablo CEU University in Madrid. He subsequently completed his specialization in Psychiatry in the Department of Psychiatry at Hospital Sant Joan de Deu in Manresa (Barcelona), where over the course of four years he acquired solid training in the bio-psycho-social model, developing his expertise across the different areas of mental health.

During his residency, he undertook training placements at Hospital Clínic de Barcelona, where he trained for several months in the psychiatric consultation-liaison unit. He also completed another placement at Hospital de Cruces in Bilbao, in the first-episode psychosis unit.

Throughout his professional career, Dr. Alvarez Guerrero has sought to complement his medical training with psychotherapeutic tools that allow him to address mental health disorders from a comprehensive perspective. For this reason, he specialized in Brief Strategic Psychotherapy through the Spanish Society of Psychosomatic Medicine and Psychotherapy, an approach focused on targeted and effective interventions.

With the aim of deepening his knowledge and promoting the rational use of treatments, he also completed a Master’s Degree in Psychopharmacology at the University of Valencia, which has enabled him to rigorously integrate the most up-to-date scientific evidence into the clinical management of psychopharmacological treatments.

He has also shown a particular interest in the field of legal psychiatry, completing an Official Master’s Degree in Legal, Forensic and Criminological Psychopathology at the Universitat Internacional de Catalunya. This training has allowed him to acquire the necessary competencies for the preparation of psychiatric expert reports in judicial and medico-legal contexts, thereby broadening the scope of his professional activity.

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Anastasiia Hladkykh

Psychiatry 15 years exp.

Dr Anastasiia Hladkykh is a physician-psychotherapist and psychologist with over 14 years of experience working with individuals struggling with various types of addictions and their families. She provides online consultations for adults, combining medical knowledge with deep psychological support and practical tools.

Key areas of expertise:

  • Addiction treatment: alcohol and drug dependence, gambling addiction, compulsive behaviours, codependent relationships.
  • Support for families of addicted individuals, behavioural correction within the family system, guidance for maintaining remission.
  • Mental health: depression, bipolar disorder, obsessive-compulsive disorder (OCD), anxiety disorders, phobias, PTSD, generalised anxiety, emotional trauma, and the psychological impact of loss or emigration.
  • Psychoeducation: explaining complex mental health concepts in simple language, helping patients and their families understand diagnoses and treatment steps.
Therapeutic approach:
  • Client-centred, straightforward, and empathetic – focused on practical outcomes and emotional stabilisation.
  • Prescribes medications when needed, but always aims to minimise unnecessary pharmaceutical use.
  • Certified in multiple evidence-based methods: CBT, NLP (Master Practitioner), Ericksonian hypnosis, symbol drama, art therapy, and systemic therapy.
  • Each consultation results in a clear, structured plan – patients leave knowing exactly what to do next.
Experience and background:
  • Member of the German association Gesundheitpraktikerin and the NGO “Mit dem Sonne in jedem Herzen.”
  • More than 18 publications in international peer-reviewed journals, translated into several languages.
  • Volunteer work with Ukrainian refugees and military personnel at the University Clinic of Regensburg.
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Daria Portnova

Psychiatry 31 years exp.

Dr Daria Portnova is a psychiatrist and psychotherapist with over 30 years of clinical experience. She works with adults and adolescents aged 14 and over, providing online psychiatric and psychotherapeutic consultations. In her practice, Dr Portnova supports patients facing the onset of mental health conditions, chronic psychiatric disorders, psychotic symptoms, trauma-related states, and complex emotional crises. Her work is structured and safety-focused, with an emphasis on stabilisation, accurate diagnosis, and long-term improvement in quality of life. Patients consult Dr Daria Portnova for the following concerns: 

  • existential crises and complex life situations;
  • loss, grief, and emotional exhaustion;
  • relationship difficulties, separation, and divorce;
  • psychological and psychiatric trauma, including complex PTSD (cPTSD);
  • anxiety disorders: generalised anxiety disorder and panic disorder;
  • social anxiety and social phobia;
  • obsessive-compulsive disorder (OCD);
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  • depressive disorders;
  • bipolar affective disorder;
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Dr Portnova combines psychiatric assessment with a psychotherapeutic approach. She works with evidence-based methods, including cognitive behavioural therapy (CBT) and third-wave approaches such as ACT, FACT, and CFT. Consultations are focused on clear clinical understanding, practical recommendations, and ongoing support over time.

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Maria Martelli

Anaesthesiology 12 years exp.

Dr Maria Martelli is a medical doctor specialising in anaesthesiology and pain medicine. She provides online consultations for adults, focusing on the assessment and management of acute, chronic, and complex pain conditions, as well as supportive care in serious illness. She graduated from the Medical University of Silesia in Katowice and completed her specialisation in Anaesthesiology and Intensive Care. Alongside hospital work, she has extensive experience in home and inpatient hospice care, supporting patients with severe pain and advanced disease. Since 2021, she has been a certified specialist and continues to work in anaesthesiology, intensive care, and pain treatment. Patients consult her for: 

  • Chronic pain lasting more than 3 months (musculoskeletal, neuropathic, mixed pain).
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Dr Martelli takes a structured, evidence-based approach, carefully analysing symptoms, previous treatments, and overall health status. Her consultations focus on realistic pain control goals, safety of therapy, and improving daily functioning. She is especially attentive to patients living with long-term pain or serious illness, providing clear explanations, compassionate guidance, and medically sound recommendations adapted to each individual situation.

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Frequently Asked Questions

Is a prescription required for MELATONIN PERRIGO 3 mg TABLETS?
MELATONIN PERRIGO 3 mg TABLETS does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in MELATONIN PERRIGO 3 mg TABLETS?
The active ingredient in MELATONIN PERRIGO 3 mg TABLETS is melatonin. This information helps identify medicines with the same composition but different brand names.
Who manufactures MELATONIN PERRIGO 3 mg TABLETS?
MELATONIN PERRIGO 3 mg TABLETS is manufactured by Perrigo Espana S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of MELATONIN PERRIGO 3 mg TABLETS online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether MELATONIN PERRIGO 3 mg TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to MELATONIN PERRIGO 3 mg TABLETS?
Other medicines with the same active substance (melatonin) include CIRCADIN 2 mg PROLONGED-RELEASE TABLETS (30 tablets), CIRCADIN 2 mg PROLONGED-RELEASE TABLETS, MELATONIN ARROTEX 2 mg PROLONGED-RELEASE TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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