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KYTRIL 1 mg FILM-COATED TABLETS

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About the medicine

How to use KYTRIL 1 mg FILM-COATED TABLETS

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Kytril1mg film-coated tablets

Granisetron

<Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor, nurse or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack

  1. What is Kytril and what is it used for
  2. What you need to know before you take Kytril
  3. How to take Kytril
  4. Possible side effects
  5. Storage of Kytril
  6. Contents of the pack and other information

1. What is Kytril and what is it used for

Kytril contains the active substance granisetron. This belongs to a group of medicines called serotonin receptor antagonists, 5-HT3, or antiemetics, which means they prevent or stop nausea and vomiting. These tablets are only for use in adults.

Kytril is used to prevent and treat nausea and vomiting (feeling sick) caused by certain treatments, such as chemotherapy or radiotherapy in cancer therapy.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you take Kytril

Do not take Kytril tablets

if you are allergic (hypersensitive) to granisetron or any of the other ingredients of Kytril (listed in section 6: Further information and the section on Important information about some of the ingredients of Kytril).

If you are not sure, consult your doctor, nurse or pharmacist before taking these tablets.

Warnings and precautions

Consult your doctor or pharmacist before starting to take these tablets, especially if you:

have problems with constipation due to intestinal obstruction

have heart problems, are receiving anticancer medicines that can be harmful to your heart and/or have some disorder of the levels of salts such as potassium, sodium or calcium (electrolyte disturbances).

are taking another medicine from the group of “5-HT3 receptor antagonists”. This group includes dolasetron and ondansetron, used like Kytril, for the treatment and prevention of nausea and vomiting.

Serotonin Syndrome is a rare but potentially life-threatening reaction that can occur with granisetron (see section 4). It can cause serious changes in how your brain, muscles, and digestive system work. The reaction can occur if you take granisetron alone,butit is more likely to occur if you take granisetron with other medicines (in particular fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, escitalopram, venlafaxine, duloxetine). The risk of serotonin syndrome also increases if you are taking medicines that contain buprenorphine or other opioids. Make sure to tell your doctor, nurse or pharmacist about all the medicines you are taking.

Children

Children should not take these tablets.

Other medicines and Kytril

Tell your doctor, nurse or pharmacist if you are using or have recently used or might take other medicines, even those bought without a prescription. This is because Kytril can interact with some medicines. Also, some medicines can interact with these tablets.

Tell your doctor, nurse or pharmacist if you are taking or might take other medicines:

medicines used to treat irregular heartbeats, other “5-HT3 receptor antagonists” such as dolasetron or ondansetron (see “Warnings and precautions”)

phenobarbital, a medicine used to treat epilepsy

ketoconazole, a medicine used to treat fungal infections

erythromycin, an antibiotic used to treat bacterial infections

SSRIs (selective serotonin reuptake inhibitors) used to treat depression and/or anxiety. For example: fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, escitalopram

SNRIs (serotonin and noradrenaline reuptake inhibitors) used to treat depression and/or anxiety. For example: venlafaxine, duloxetine.

  • Medicines that contain buprenorphine or other opioids.

Pregnancy and breastfeeding

Do not take these tablets if you are pregnant, trying to become pregnant or are breastfeeding, unless your doctor has told you to.

If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor, nurse or pharmacist for advice before taking this medicine.

Driving and using machines

The effect of Kytril on the ability to drive and use machines is negligible or non-existent.

Kytril contains

Kytril contains lactose (a type of sugar). If your doctor has told you that you have an intolerance to some sugars, consult them before taking this medicine.

Kytril contains less than 23 mg (1mmol) of sodium per dose (1mg), so it is essentially “sodium-free”.

3. How to take Kytril

Follow exactly the administration instructions of this medicine given by your doctor. In case of doubt, consult your doctor, nurse or pharmacist again

The recommended dose of Kytril varies from one patient to another. This depends on age, weight, and whether you are taking other medicines to prevent or treat nausea and vomiting. Your doctor will decide how much you should take.

Prevention of nausea or vomiting (feeling sick)

The first dose of Kytril will usually be given one hour before your radio or chemotherapy. The dose should be taken as:

  • one 1 mg tablet twice a day or
  • two 1 mg tablets once a day or
  • one 2 mg tablet once a day

for up to a maximum of one week after your radio or chemotherapy.

Treatment of nausea or vomiting (feeling sick)

The dose will usually be:

  • one 1 mg tablet twice a day or
  • two 1 mg tablets once a day or
  • one 2 mg tablet once a day

If you take more Kytril than you should

If you think you have taken more tablets than you should, tell your doctor or nurse. You can also call the Toxicology Information Service on 91 562 04 20, stating the medicine and the amount taken.

Among the symptoms of overdose are included a mild headache (cephalea). You will be treated according to your symptoms.

If you forget to take Kytril

If you think you have forgotten to take your medicine, ask your doctor or nurse.

Do not take a double dose to make up for forgotten doses.

If you stop taking Kytril

Do not stop taking your medicine before you have finished the treatment. If you stop the treatment, your symptoms may come back.

If you have any other questions about the use of this medicine, ask your doctor, nurse or pharmacist

.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. If you notice any of the following side effects, you should see your doctor immediately:

  • allergic reactions (anaphylaxis). The signs can include swelling of the throat, or your face, lips and mouth becoming swollen, and difficulty breathing or swallowing
  • Serotonin Syndrome. The signs can include diarrhea, nausea, vomiting, high temperature and blood pressure, excessive sweating and rapid heartbeat, agitation, confusion, hallucination, shivering, muscle tremors, shaking or stiffness, loss of coordination and restlessness. This reaction can occur if you take Kytril alone or, more likely, with other medicines (see “Warnings and precautions”)

Other side effects that may occur while taking this medicine are:

Very common, may affect more than 1 in 10 people

headache

constipation. Your doctor will monitor your condition.

Common, may affect up to 1 in 10 people

difficulty sleeping (insomnia)

blood tests show changes in liver function

diarrhea

Uncommon, may affect up to 1 in 100 people

skin rash or an allergic reaction or hives. The signs can include red spots that itch.

changes in heartbeats (rhythm) and changes in the ECG (electrocardiogram)

abnormal involuntary movements, such as tremors, muscle stiffness and muscle contractions

  • Serotonin Syndrome. The signs can include diarrhea, nausea, vomiting, fever and high blood pressure, excessive sweating and rapid heartbeat, agitation, confusion, hallucinations, shivering, muscle spasms, shaking or stiffness, loss of coordination and restlessness.

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Spanish Pharmacovigilance System for human use medicines, https://www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Kytril

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the blister and carton after “EXP”. The expiry date is the last day of the month stated.

This medicine does not require any special storage conditions.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help protect the environment.

6. Contents of the pack and other information

Composition of Kytril

The active substance is granisetron

Each film-coated tablet contains 1 mg of granisetron (as granisetron hydrochloride).

The other ingredients are:

Lactose monohydrate

Hypromellose

Sodium starch glycolate

Microcrystalline cellulose

Magnesium stearate

Tablet coating:

Hypromellose

Titanium dioxide (E171)

Macrogol 400

Polysorbate 80

Appearance of Kytril and contents of the pack

The tablets are biconvex triangular, white to almost white and bear the inscription “K1” on one side. They are supplied in opaque PVC/Aluminum blister packs containing 2 or 10 tablets per pack.

Not all pack sizes may be marketed.

Other presentations:

Kytril 3 mg/3 ml solution for injection (for hospital use)

Kytril 1 mg/1 ml solution for injection (for hospital use)

Marketing authorisation holder and manufacturer

Marketing authorisation holder

Atnahs Pharma Netherlands B.V.

Copenhagen Towers

Ørestads Boulevard 108, 5.tv

DK-2300 København S

Denmark

Manufacturer

IL CSM Clinical Supplies Management

Marie-Curie-Strasse 8

Lörrach

Baden-Württemberg

79539, Germany

Or

Waymade Plc

Sovereign House

Miles Gray Road

Basildon

Essex SS14 3FR

United Kingdom

This medicine is authorised in the Member States of the European Economic Area and in the United Kingdom (Northern Ireland) under the following names:

Austria, Belgium, Czech Republic, Estonia, Finland, France, Ireland, Italy, Latvia, Netherlands, Slovakia, Slovenia, Spain, United Kingdom (Northern Ireland): Kytril

Germany: Kevatril

Date of last revision of this leaflet: March 2025

Other sources of information

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for KYTRIL 1 mg FILM-COATED TABLETS

Discuss questions about KYTRIL 1 mg FILM-COATED TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Sviatoslav Chekhun

Oncology 13 years exp.

Dr. Sviatoslav Chekhun is a medical oncologist with international clinical and research experience, specializing in modern medical oncology and a personalized approach to cancer treatment.

Currently (since 2025), he works as a Medical Oncologist at Institut Català d’Oncologia (Girona, Spain). Previously, he completed his residency in Medical Oncology and was involved in clinical research at Hospital Universitari Germans Trias i Pujol.

Dr. Chekhun has a strong academic and scientific background. He served as a lecturer in Internal Medicine at O.O. Bohomolets National Medical University and conducted research in experimental oncology at the R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology.

Earlier in his career, he worked as a medical oncologist at the Kyiv City Clinical Oncological Center and contributed to regulatory evaluation of medicinal products at the State Expert Center of the Ministry of Health of Ukraine.

When to consult Dr. Chekhun:

  •  for diagnosis or clarification of a cancer diagnosis
  •  to obtain a second opinion on an existing treatment plan 
  •  when you need a personalized treatment strategy 
  •  for interpretation of test results, CT, MRI, PET-CT, and biopsies 
  •  when choosing between treatment options (chemotherapy, targeted therapy, immunotherapy) 
  •  in case of doubts about treatment strategy or disease progression 

Consultation format

Dr. Chekhun provides online consultations, where you can receive:

  •  expert second opinion 
  •  detailed case review 
  •  recommendations based on current international treatment guidelines 
  •  personalized treatment and follow-up plan 

Important:
Prescription and monitoring of medications must be carried out by your treating physician in an in-person (offline) setting. An online consultation does not replace a face-to-face visit but helps you make more informed decisions about your treatment.

Dr. Sviatoslav Chekhun combines clinical practice, research, and international experience, enabling him to provide patients with modern, evidence-based approaches in oncology.

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General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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Alina Tsurkan

Family medicine 13 years exp.

Dr. Alina Tsurkan is a licensed family medicine physician based in Portugal, offering online consultations for adults and children. She provides professional primary care, with a focus on prevention, accurate diagnosis, and long-term management of acute and chronic conditions.

Dr. Tsurkan supports patients with a wide range of health issues, including:

  • Respiratory infections: cold, flu, bronchitis, pneumonia, and lingering coughs.
  • ENT conditions: sinusitis, tonsillitis, otitis (ear infections), sore throat, allergic rhinitis.
  • Eye conditions: allergic or infectious conjunctivitis, red eyes, irritation.
  • Digestive issues: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), constipation, bloating, nausea.
  • Urinary and reproductive health: urinary tract infections (UTIs), cystitis, prevention of recurrent infections.
  • Chronic diseases: hypertension, elevated cholesterol, weight management.
  • Neurological complaints: headaches, migraines, sleep disturbances, fatigue, general weakness.
  • Children’s health: fever, infections, digestive issues, follow-ups, vaccination guidance.

She also provides:

  • IMT medical certificates for driving licence exchange in Portugal.
  • Personalised preventive care and wellness consultations.
  • Interpretation of test results and medical reports.
  • Follow-up care and medication review.
  • Support in managing multiple coexisting conditions.
  • Remote prescription management and medical documentation.

Dr. Tsurkan’s approach is evidence-based and holistic. She works closely with each patient to develop an individualised care plan that addresses both symptoms and root causes. Her goal is to empower patients to take control of their health and maintain well-being through lifestyle adjustments, routine check-ups, and early intervention.

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Taisiia Proida

Family medicine 7 years exp.

Taisiia Proida is a general practitioner with a specialization in mental health and a cognitive behavioral therapist (CBT), a member of the European Psychiatric Association. She offers online consultations for adults aged 18 and over, combining evidence-based medicine with an individualised approach to mental health care. She specialises in consultations and ongoing support for a wide range of mental health concerns, including: 

  • Mood disorders: depression, bipolar disorder, postpartum depression.
  • Anxiety disorders: generalised anxiety, OCD, panic attacks, phobias.
  • Post-traumatic stress disorder (PTSD) and complex PTSD.
  • Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). Assessment is provided only after an initial psychiatric evaluation and during a follow-up appointment.
  • Personality disorders and emotional instability.
  • Cyclothymia and mood fluctuations.
  • Schizophrenia spectrum and related conditions.

Dr. Proida combines clinical expertise with an empathetic approach, offering structured support based on evidence-based practices. Her work integrates CBT techniques with medical management, with a focus on anxiety and depressive disorders. She works with clients from different countries and cultural backgrounds, adapting her communication style and recommendations to individual needs. With experience in international clinical trials (Pfizer, Merck), she values clarity, trust, and collaborative partnership in patient care.

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Alexander Nazarchuk

Allergology 7 years exp.

Dr. Alexander Nazarchuk is a physician specialising in allergology and internal medicine. He provides online consultations for adults, following the principles of evidence-based medicine — no outdated treatments or unnecessary tests, with clear explanations and a personalised approach. He helps patients with a wide range of allergic and therapeutic conditions, from common day-to-day complaints to complex cases involving allergies, gastrointestinal issues, cardiovascular concerns, respiratory symptoms, and more.

You can consult Dr. Nazarchuk for:

  • Test interpretation and guidance on diagnostic plans.
  • Allergic rhinitis, hay fever, bronchial asthma (including severe cases).
  • Food and drug allergies, skin rashes, angioedema.
  • Atopic dermatitis, urticaria, contact allergies.
  • Allergen-specific immunotherapy (AIT) – initiation and ongoing management.
  • Abdominal pain, bloating, changes in bowel habits, nausea, heartburn.
  • High blood pressure and adjustment of baseline antihypertensive therapy.
  • Hyperlipidaemia and elevated cholesterol.
  • Cough, nasal congestion, fever, sore throat.
  • Anaemia, including iron deficiency and related conditions.
  • Other issues related to allergology and internal medicine.

During consultations, Dr. Nazarchuk takes a thorough, structured approach — analysing symptoms, identifying potential causes, and helping patients make informed decisions. Whether treatment, further investigation, or monitoring is needed, he explains each step clearly so you understand your health and how best to manage it.

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Frequently Asked Questions

Is a prescription required for KYTRIL 1 mg FILM-COATED TABLETS?

KYTRIL 1 mg FILM-COATED TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in KYTRIL 1 mg FILM-COATED TABLETS?

The active ingredient in KYTRIL 1 mg FILM-COATED TABLETS is granisetron. This information helps identify medicines with the same composition but different brand names.

Who manufactures KYTRIL 1 mg FILM-COATED TABLETS?

KYTRIL 1 mg FILM-COATED TABLETS is manufactured by Atnahs Pharma Netherlands Bv.. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of KYTRIL 1 mg FILM-COATED TABLETS online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether KYTRIL 1 mg FILM-COATED TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy KYTRIL 1 mg FILM-COATED TABLETS in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy KYTRIL 1 mg FILM-COATED TABLETS in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to KYTRIL 1 mg FILM-COATED TABLETS?

Other medicines with the same active substance (granisetron) include GRANISETRON ALTAN 3 mg/50 ml SOLUTION FOR INFUSION, GRANISETRON AUROVITAS SPAIN 1 mg FILM-COATED TABLETS, GRANISETRON KABI 1 mg/ml CONCENTRATE FOR INJECTION SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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