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HEDETUS 5.4 mg/ml SYRUP

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About the medicine

How to use HEDETUS 5.4 mg/ml SYRUP

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the Patient

Hedetus, 5.4 mg/ml, Syrup

Dry Extract of Ivy Leaf

Read this package leaflet carefully before you start taking this medicine, because it contains important information for you.

Follow exactly the administration instructions of the medicine contained in this package leaflet or as indicated by your doctor or pharmacist.

  • Keep this package leaflet, as you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience side effects, consult your doctor or pharmacist, even if they are not listed in this package leaflet. See section 4.
  • You should consult a doctor if your symptoms worsen or do not improve after 5 days.

Contents of the Package Leaflet

  1. What is Hedetus and what is it used for
  2. What you need to know before taking Hedetus
  3. How to take Hedetus
  4. Possible side effects
  5. Storage of Hedetus
  6. Package Contents and Additional Information

1. What is Hedetus and what is it used for

Hedetus is a herbal medicine used as an expectorant in cases of productive cough. It contains the dry extract of ivy leaf (Hedera helixL., folium).

Hedetus is indicated in adults, adolescents, and children over 2 years of age.

You should consult a doctor if your symptoms worsen or do not improve after 5 days.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before taking Hedetus

Do not take this medicine:

  • if you are allergic to ivy, other members of the Araliaceaefamily, or to any of the other components of this medicine (listed in section 6.1).
  • in children under 2 years of age, as respiratory symptoms can generally worsen in this patient group.

Warnings and Precautions

Consult your doctor before taking this medicine:

  • if you have difficulty breathing, fever, or purulent sputum
  • if symptoms persist for more than 5 days, or if you are using opioid antitussives, such as codeine or dextromethorphan
  • if you have gastritis or gastric ulcer

Children

  • Do not use in children under 2 years of age. See the section "Do not take this medicine"
  • If children between 2 and 4 years of age have persistent or recurrent cough, a medical diagnosis will be required before starting treatment.

Taking Hedetus with Other Medicines

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.

Taking Hedetus with Food, Drinks, and Alcohol

No interactions with food, drinks, or alcohol are known.

Pregnancy, Breastfeeding, and Fertility

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

Pregnancy

Hedetus should not be taken during pregnancy.

Breastfeeding

Hedetus should not be used during breastfeeding.

Fertility

No data on fertility are available.

Driving and Using Machines

No studies have been conducted on the effects on the ability to drive and use machines.

Hedetus Contains:

  • 292.6 mg/ml sorbitol(E420). Sorbitol may have a mild laxative effect. Energy value 2.6 kcal/g sorbitol. If your doctor has told you that you have an intolerance to certain sugars, consult them before taking this medicine.
  • 2.3 mg/ml . If your doctor has told you that you have an intolerance to certain sugars, consult them before taking this medicine.

3. How to Take Hedetus

Follow exactly the administration instructions of the medicine contained in this package leaflet or as indicated by your doctor or pharmacist. In case of doubt, ask your doctor or pharmacist.

The recommended dose is:

Age

Dose

Adults, adolescents, and elderly

5 ml, 2 to 3 times a day

Children between 6 and 12 years of age

5 ml, 2 times a day

Children between 2 and 5 years of age

2.5 ml, 2 times a day

Hedetus should be taken orally. The package contains a measuring cup to measure the correct dose.

There are not enough data to make specific dosage recommendations in case of renal/hepatic insufficiency.

If symptoms persist for more than 5 days of using the medicine, you should consult a doctor.

If You Take More Hedetus Than You Should

If you have taken more medicine than you should, consult your doctor or pharmacist immediately. Overdose of ivy leaf extract may cause nausea, vomiting, diarrhea, and nervousness. In case of symptoms of poisoning or overdose, symptomatic treatment will be applied.

If You Forget to Take Hedetus

Do not take a double dose to make up for forgotten doses.

If You Stop Taking Hedetus

Not applicable

If you have any other questions about the use of this medicine, ask your doctor or pharmacist.

Medicine questions

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Discuss your symptoms and treatment with a doctor online.

4. Possible Side Effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. The following side effects have been reported (frequency unknown):

  • Gastrointestinal disorders such as nausea, vomiting, or diarrhea.
  • Hypersensitivity reactions, such as hives, skin rash, difficulty breathing

If you notice symptoms of hypersensitivity, stop taking Hedetus and consult your doctor.

Reporting Side Effects

If you experience any side effects, consult your doctor or pharmacist, even if they are not listed in this package leaflet. You can also report them directly through the Spanish Medicines Agency's website (www.notificaRAM.es). By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Hedetus

Keep this medicine out of the sight and reach of children.

Store below 25°C.

Once opened, the syrup expires after 28 days.

Do not use this medicine after the expiration date stated on the carton and bottle after "EXP". The expiration date is the last day of the month indicated.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Package Contents and Additional Information

Composition of Hedetus:

The active substance is:

Dry extract of ivy leaf (Hedera helixL., folium). 1 ml of syrup (equivalent to 1.1 g) contains 5.4 mg of extract (in the form of dry extract) of Hedera helixL., folium(ivy leaf) (5-7.5:1). Extraction solvent: Ethanol 30% (m/m).

The other components are:

Lactose monohydrate, sorbitol (E420), benzoic acid (E210), xanthan gum, ammonium glycyrrhizate, essential oil of Eucalyptusradiata (Sieber ex DC), and purified water.

Appearance and Package Contents

Green, translucent liquid with a characteristic odor in a 200 ml amber glass bottle with a child-resistant plastic cap and measuring cup.

Marketing Authorization Holder and Manufacturer

Conforma NV

Zenderstraat 10

9070 Destelbergen

Belgium

This medicine is authorized in the Member States of the European Economic Area under the following names:

BE: Pulmocap Hedera, siroop

NL: Pulmocap Hedera, stroop

LU: Pulmocap Hedera, sirop

FR: Hedetus, sirop

DE: Pulmocap Hedera, Sirup

PL: Mituret

IT: Edera Conforma

ES: Hedetus, jarabe

PT: Pulmocap Hedera, xarope

AT: Pulmocap Hedera, Sirup

Date of Last Revision of this Package Leaflet: 12/2017

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for HEDETUS 5.4 mg/ml SYRUP

Discuss questions about HEDETUS 5.4 mg/ml SYRUP, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Tarek Agami

General medicine 11 years exp.

Dr. Tarek Agami is a general practitioner registered in both Portugal and Israel, with broad experience in family and preventive medicine. He offers online consultations for adults and children, providing personalised support for primary care needs, chronic disease management, and everyday health concerns.

Dr. Agami received clinical training and worked in leading medical institutions in Israel (Kaplan Medical Center, Barzilai Medical Center, Wolfson Medical Center) and Portugal (European Healthcare City, Viscura Internacional, Hospital Dr. José Maria Grande, Hospital Vila Franca de Xira). His approach combines international medical standards with individualised attention to each patient.

Main areas of consultation:

  • Diagnosis and treatment of acute and chronic conditions (high blood pressure, diabetes, respiratory infections, cardiovascular symptoms)
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  • Medical support during travel or after relocation
  • Treatment adjustments and lifestyle recommendations based on your personal history
Dr. Agami provides medical support for patients using GLP-1 medications (such as Ozempic or Mounjaro) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Portugal and Israel.

Dr. Agami is committed to evidence-based, patient-centred care, ensuring that each person receives trusted medical support tailored to their health goals.

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Nuno Tavares Lopes

Family medicine 18 years exp.

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
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  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

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Anastasiia Shalko

Family medicine 13 years exp.

Dr. Anastasiia Shalko is a general practitioner with a background in both paediatrics and general medicine. She graduated from Bogomolets National Medical University in Kyiv and completed her paediatric internship at the P.L. Shupyk National Medical Academy of Postgraduate Education. After working as a paediatrician in Kyiv, she relocated to Spain, where she has been practising general medicine since 2015, providing care for both adults and children.

Her work focuses on urgent, short-term medical concerns – situations where patients need quick guidance, symptom assessment and clear next steps. She helps people understand whether their symptoms require in-person evaluation, home management or a change in treatment. Common reasons for booking an online consultation include:

  • acute respiratory symptoms (cough, sore throat, runny nose, fever)
  • viral illnesses such as colds and seasonal infections
  • gastrointestinal complaints (nausea, diarrhoea, abdominal pain, gastroenteritis)
  • sudden changes in how a child or adult feels
  • questions about existing treatment and whether adjustments are needed
  • renewal of prescriptions when clinically appropriate
Dr. Shalko works specifically with urgent and short-term problems, providing practical recommendations and helping patients determine the safest next step. She explains symptoms clearly, guides patients through decision-making and offers straightforward medical advice for everyday acute issues.

She does not provide long-term management of chronic conditions, ongoing follow-up or comprehensive care plans for complex long-term illnesses. Her consultations are designed for acute symptoms, sudden concerns and situations where timely medical input is important.

With clinical experience in both paediatrics and general medicine, Dr. Shalko confidently supports adults and children. Her communication style is clear, simple and reassuring, helping patients feel informed and supported throughout the consultation.

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Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques.

For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance.

Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults.

In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions.

Patients commonly seek his care for:

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
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  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns
Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.
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Frequently Asked Questions

Is a prescription required for HEDETUS 5.4 mg/ml SYRUP?
HEDETUS 5.4 mg/ml SYRUP does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in HEDETUS 5.4 mg/ml SYRUP?
The active ingredient in HEDETUS 5.4 mg/ml SYRUP is Hederae helicis folium. This information helps identify medicines with the same composition but different brand names.
Who manufactures HEDETUS 5.4 mg/ml SYRUP?
HEDETUS 5.4 mg/ml SYRUP is manufactured by Conforma Nv. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of HEDETUS 5.4 mg/ml SYRUP online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether HEDETUS 5.4 mg/ml SYRUP is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to HEDETUS 5.4 mg/ml SYRUP?
Other medicines with the same active substance (Hederae helicis folium) include ABRILAR SYRUP, ACTUATOS 35 mg ORAL SOLUTION IN SACHETS, ACTUATOS 7 mg/ml SYRUP. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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