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DESMOPRESSIN STADA 120 micrograms SUBLINGUAL TABLETS

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About the medicine

How to use DESMOPRESSIN STADA 120 micrograms SUBLINGUAL TABLETS

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the Patient

Desmopresina Stada 120 micrograms sublingual tablets EFG

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack

  1. What is Desmopresina Stada and what is it used for
  2. What you need to know before you take Desmopresina Stada
  3. How to take Desmopresina Stada
  4. Possible side effects
  5. Storage of Desmopresina Stada
  6. Contents of the pack and other information

1. What is Desmopresina Stada and what is it used for

Desmopressin, the active substance of Desmopresina Stada, is an analogue of the natural hormone vasopressin, which regulates the ability of the kidneys to concentrate urine.

Desmopressin is used for the treatment of:

  • Central diabetes insipidus (a disorder of the pituitary gland that leads to intense thirst and the production of a large amount of pale, watery urine).
  • Nocturnal enuresis in children from 5 years of age with normal ability to concentrate urine (involuntary urination at night during sleep).
  • Nocturia (a condition in which a person wakes up frequently during the night to urinate) in adults under 65 years of age.
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2. What you need to know before you take Desmopresina Stada

Do not take Desmopresina Stada:

  • if you are allergic to desmopressin or any of the other ingredients of this medicine (listed in section 6)
  • if you suffer from polydipsia (abnormally high fluid intake), heart failure, and other conditions that require treatment with diuretics
  • if you have moderately or severely reduced kidney function
  • if you have low sodium levels in the blood
  • if you cannot adhere to fluid restriction
  • if you have altered hormonal secretion (so-called SIADH)
  • if you are over 65 years of age and suffer from nocturia (see section 1)
  • if your child is under 5 years of age and suffers from nocturnal enuresis (see section 1)

Warnings and precautions

Control of nocturnal enuresis (involuntary urination at night) in children begins with lifestyle measures and a bedwetting alarm (a device that makes a sound or vibrates when it gets wet). If these measures fail or pharmacological therapy is needed, treatment with desmopressin can be initiated.

Consult your doctor before starting to take this medicine

  • if you have coronary artery disease (blood vessels that supply the heart) or high blood pressure
  • if you have a thyroid disease (gland in the neck) or adrenal gland disease (gland above the kidney).
  • if during treatment you have an illness that causes fever, vomiting, diarrhea.
  • if during your treatment you feel headache, lack of appetite, nausea, vomiting, weight gain, confusion (difficulty understanding words, difficulties with attention) or convulsions (violent and involuntary contractions of one or more limbs); these symptoms may be signs of a dangerous condition known as hyponatremia (low sodium level in the blood)
    • for the treatment of central diabetes insipidus: you should reduce water intake and consult your doctor immediately. Your doctor will reduce the dose or interrupt treatment for a few hours.
    • for the treatment of nocturnal enuresis or nocturia: you should stop treatment, reduce fluid intake, and consult your doctor immediately.
  • if you have a risk of increased pressure in the skull

When treating nocturnal enuresis and nocturia, fluid intake should be limited to the minimum possible to control thirst during the period between 1 hour before and 8 hours after taking this medicine.

Desmopressin should be used with caution in patients with fluid balance disorders. Talk to your doctor if, in relation to an acute illness, you have a hydroelectrolytic imbalance.

Children

In children, the use of this medicine should be under the supervision of an adult.

Do not give this medicine to children under 5 years of age.

Other medicines and Desmopresina Stada

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including those without a prescription.

The effect of this medicine may increase, with a greater risk of abnormal fluid accumulation in the body, if taken at the same time as certain medicines used to treat:

  • depression (such as tricyclic antidepressants, selective serotonin reuptake inhibitors)
  • psychosis (such as chlorpromazine)
  • epilepsy (such as carbamazepine)
  • diabetes (sulfonylureas, for example, chlorpropamide)
  • diarrhea (such as loperamide)
  • pain and inflammation (non-steroidal anti-inflammatory drugs)

The effect of this medicine may decrease if taken at the same time as certain medicines for:

  • stomach gas (such as dimethicone)

Use of Desmopresina Stada with beverages

If you are taking this medicine for enuresis or nocturia, you should limit fluid intake from 1 hour before taking the tablet to 8 hours after taking it.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Experience with use during pregnancy is limited.

Desmopressin passes into breast milk, but it is unlikely to affect breastfed babies.

Driving and using machines

Desmopressin has a negligible influence on the ability to drive and use machines.

Desmopresina Stada contains lactose and sodium

This medicine contains lactose. If your doctor has told you that you have an intolerance to some sugars, consult them before taking this medicine.

This medicine contains less than 1 mmol of sodium (23 mg) per sublingual tablet; this is essentially “sodium-free”.

3. How to take Desmopresina Stada

Always take this medicine exactly as your doctor has told you. If you are not sure, check with your doctor or pharmacist.

The dose will be determined by your doctor, who will adjust it individually for you.

This medicine should be taken at the same time every day.

The sublingual tablet should be placed under the tongue where it dissolves without water.

Diabetes insipidus:

The usual dose for adults and children is 1 to 2 tablets under the tongue (60 microgram tablet) 3 times a day.

Nocturnal enuresis:

The usual dose is 1-2 tablets (120 microgram tablet) under the tongue at bedtime. You should take this medicine at bedtime. Fluid intake should be limited.

Your doctor will check you every three months to see if treatment should be continued. Your doctor may set a treatment-free period of at least one week.

Nocturia in adults

The usual dose is 1 tablet (60 microgram tablet) under the tongue before bedtime.

Fluid intake should be limited.

Use in children

This medicine is used to treat diabetes insipidus and nocturnal enuresis (see above for the dose for the different treatment conditions). The dose is the same for children and adults only for diabetes insipidus.

If you take more Desmopresina Stada than you should

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, telephone (91) 562 04 20, indicating the medicine and the amount taken. It is recommended to take the packaging and the leaflet to the healthcare professional.

If you take more medicine than you should or if, for example, a child has accidentally ingested the medicine, contact a doctor, hospital, or pharmacist immediately for a risk assessment and advice.

Taking too much desmopressin can prolong the effect of this medicine and increase the risk of fluid retention in the body and low sodium levels in the blood. Symptoms of severe fluid retention include convulsions and loss of consciousness.

If you forget to take Desmopresina Stada

Do not take a double dose to make up for forgotten tablets.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

If you stop taking Desmopresina Stada

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Medicine questions

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4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

If fluid intake is not limited according to the above instructions, abnormal amounts of fluid can accumulate in your body, which can cause headaches, stomach pain, nausea/vomiting, weight gain, dizziness, confusion, general malaise, feeling of spinning, and, in severe cases, convulsions and coma.

These signs may reflect more or less significant water retention. They usually appear with high doses of this medicine and disappear when the dose is reduced.

Adults

Very common(may affect more than 1 in 10 people):

  • Headache

Common(may affect up to 1 in 10 people):

  • Low sodium levels in the blood
  • Dizziness
  • Hypertension
  • Stomach pain
  • Nausea
  • Diarrhea
  • Constipation
  • Vomiting
  • Bladder and urethra discomfort
  • Swelling of hands, arms, feet, or legs
  • Fatigue

Uncommon(may affect up to 1 in 100 people)

  • Sleep disorders
  • Somnolence
  • Paresthesia
  • Visual disturbances
  • Feeling of spinning (vertigo)
  • Feeling your heartbeat
  • Low blood pressure when standing up from a lying position
  • Breathing difficulties
  • Stomach discomfort (indigestion, flatulence, bloating)
  • Sweating
  • Itching
  • Rash
  • Urticaria
  • Muscle spasms
  • Muscle pain
  • Chest pain
  • Flu-like symptoms
  • Weight gain
  • Increased liver enzymes
  • Low potassium levels in the blood.

Rare(may affect up to 1 in 1,000 people)

  • Confusion
  • Allergic skin inflammation.

Frequency not known(frequency cannot be estimated from the available data)

  • Anaphylactic reaction (severe allergic reaction)
  • Dehydration
  • High sodium levels in the blood
  • Convulsions
  • Weakness
  • Coma.

Children

Common(may affect up to 1 in 10 people)

  • Headache.

Uncommon(may affect up to 1 in 100 people)

  • Rapidly changing emotions.
  • Aggression
  • Nausea
  • Stomach pain
  • Vomiting
  • Diarrhea
  • Bladder and urethra discomfort
  • Swollen hands and feet
  • Fatigue.

Rare(may affect up to 1 in 1,000 people)

  • Anxiety
  • Nightmares
  • Mood changes
  • Somnolence
  • Hypertension
  • Irritability.

Frequency not known(frequency cannot be estimated from the available data)

  • Anaphylactic reaction (severe allergic reaction)
  • Low sodium levels in the blood
  • Abnormal behavior
  • Emotional disturbances
  • Depression
  • Hallucinations
  • Sleep disorders
  • Reduced attention
  • Increased muscle movements.
  • Cramp
  • Nosebleeds
  • Rash
  • Allergic skin inflammation.
  • Sweating
  • Urticaria.

Reporting of side effects:

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Spanish Medicines Agency's website: http://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Desmopresina Stada

Keep this medicine out of the sight and reach of children.

Store in the original packaging to protect from moisture.

This medicine does not require any special storage temperature.

Do not use this medicine after the expiry date which is stated on the carton, after EXP. The expiry date is the last day of the month shown.

Medicines should not be disposed of via wastewater or household waste. Return any unused medicine to your pharmacist. Ask your pharmacist how to dispose of medicines no longer required. This will help to protect the environment.

6. Contents of the pack and other information

Composition of Desmopresina Stada

  • The active substance is desmopressin

Each sublingual tablet contains 120 micrograms of desmopressin (as acetate).

  • The other ingredients are: lactose monohydrate, corn starch, citric acid, sodium croscarmellose, and magnesium stearate.

Appearance and packaging

Desmopresina Stada are white or almost white, octagonal, biconvex tablets engraved with 'II' on one face and smooth on the other, approximately 6.5 mm in length/width.

Desmopresina Stada is supplied in a cardboard box containing standard or unit-dose blister packs with an integrated desiccant layer of aluminum/aluminum with 10 tablets each, in packs of 10, 30, and 100 sublingual tablets.

Not all pack sizes may be marketed.

Marketing authorization holder and manufacturer

Marketing authorization holder

Laboratorio STADA, S.L.

Frederic Mompou 5

08960 Sant Just Desvern (Barcelona)

Spain

[email protected]

Manufacturer

Haupt Pharma Münster GmbH

Schleebrüggenkamp 15,

D-48159 Münster,

Germany

or

Adalvo Ltd.

Malta Life Sciences Park,

Building 1, Level 4, Sir Temi Zammit Buildings,

San Gwann, SGN 3000

Malta

or

STADA Arzneimittel AG

Stadastraße 2-18

61118 Bad Vilbel

Germany

Date of last revision of this leaflet:June 2024

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

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Frequently Asked Questions

Is a prescription required for DESMOPRESSIN STADA 120 micrograms SUBLINGUAL TABLETS?
DESMOPRESSIN STADA 120 micrograms SUBLINGUAL TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in DESMOPRESSIN STADA 120 micrograms SUBLINGUAL TABLETS?
The active ingredient in DESMOPRESSIN STADA 120 micrograms SUBLINGUAL TABLETS is desmopressin. This information helps identify medicines with the same composition but different brand names.
How much does DESMOPRESSIN STADA 120 micrograms SUBLINGUAL TABLETS cost in pharmacies?
The average pharmacy price for DESMOPRESSIN STADA 120 micrograms SUBLINGUAL TABLETS is around 34.16 EUR. Prices may vary depending on the manufacturer and dosage form.
Who manufactures DESMOPRESSIN STADA 120 micrograms SUBLINGUAL TABLETS?
DESMOPRESSIN STADA 120 micrograms SUBLINGUAL TABLETS is manufactured by Laboratorio Stada S.L.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of DESMOPRESSIN STADA 120 micrograms SUBLINGUAL TABLETS online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether DESMOPRESSIN STADA 120 micrograms SUBLINGUAL TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to DESMOPRESSIN STADA 120 micrograms SUBLINGUAL TABLETS?
Other medicines with the same active substance (desmopressin) include DESMIRIN 360 micrograms/ml ORAL SOLUTION, DESMOPRESSIN ARISTO 120 MICROGRAMS SUBLINGUAL TABLETS, DESMOPRESSIN ARISTO 240 MICROGRAMS SUBLINGUAL TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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